San Mateo Vacations from $516

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Your San Mateo Vacation

When a city break is calling, answer it with a San Mateo vacation package. The neighborhood of Santa Marianita, which is great for watersports, dining and views, makes a great base for your adventures. If some sightseeing is on the agenda during your trip to San Mateo, stop by popular attractions such as Universidad Laica Eloy Alfaro de Manabi. Whoever you're going away with and whether your budget is big or small, your ultimate San Mateo vacation is just a few clicks away with Expedia.

The Latest San Mateo vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Colón Salinas

Hotel Colón Salinas

4 out of 5
per person
Aug 14 - Aug 17
found 23 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Guayaquil (GYE)
7.4/10 Good! (187 reviews)
nice location, good meals and the hotel is clean , nice and the area is safe!

Reviewed on Feb 17, 2025

Hotel Rio Guayas

Hotel Rio Guayas

2.5 out of 5
Las Peñas
Save 100% on your flight
per person
Sep 20 - Sep 23
found 21 hours ago
Roundtrip non-stop flight included
Miami (MIA) to Guayaquil (GYE)
No reviews
Santa Ana Guayaquil Lux Coliving Ecuador

Santa Ana Guayaquil Lux Coliving Ecuador

3 out of 5
Puerto Santa Ana
per person
Aug 22 - Aug 25
found 21 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE)
5/10 (4 reviews)
Mantahost Hotel

Mantahost Hotel

4 out of 5
Barbasquillo
per person
Sep 3 - Sep 7
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
8.6/10 Excellent! (283 reviews)
Las habitaciones están muy viejas. Había un refrigerador que sonaba muy duro

Reviewed on Mar 21, 2025

Balandra Hotel

Balandra Hotel

4 out of 5
per person
Sep 3 - Sep 7
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Guayaquil (GYE)
9.2/10 Wonderful! (182 reviews)
Great hotel, fantastic staff.

Reviewed on Apr 27, 2025

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Discover the most popular places to visit in San Mateo

Universidad Laica Eloy Alfaro de Manabi

4.5/5(3 reviews)

Walk around the campus at Universidad Laica Eloy Alfaro de Manabi during your visit to Manta. Wander the seaside and beaches in the area.

Universidad Laica Eloy Alfaro de Manabi

Manta Port

4.5/5(11 reviews)

Explore the waterfront in Manta with a trip to Manta Port. Wander the beaches and seaside in the area.

Manta Port

Mall del Pacífico

You can search for that perfect souvenir at Mall del Pacífico during your trip to Manta. Wander the beaches and seaside in the area.

Mall del Pacífico

San Mateo Hotel Deals

WATCH & HEAR THE WAVES FROM BEAUTIFUL OCEAN FRONT CONDO
WATCH & HEAR THE WAVES FROM BEAUTIFUL OCEAN FRONT CONDO
SANTA MARIANITA
SELF ISOLATION IN MANTA ON THE BEACH DURING COVID 19
"Property very well maintained with total security. You see some activity on the weekends but during the week days you got the beach pretty much to yourself. Caretaker was quick to response and address minor details. I would definitely come back for another stay."

Reviewed on Mar 27, 2020

Get rates
WATCH & HEAR THE WAVES FROM BEAUTIFUL OCEAN FRONT CONDO
Wyndham Manta Sail Plaza Hotel & Convention Center
Wyndham Manta Sail Plaza Hotel & Convention Center
4.5 out of 5
Via Barbasquillo junto a Mykonos, Manta, Manabi
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from Jul 21 to Jul 22
$121 total
Jul 21 - Jul 22
7.8/10 Good! (335 reviews)
"The best hotel in manta"

Reviewed on Jul 6, 2025

Wyndham Manta Sail Plaza Hotel & Convention Center
Oro Verde Manta
Oro Verde Manta
4.5 out of 5
Calle 23, Av. Malecon, Manta, Manabi
$146 nightly
The price is $161 total per night from Jul 27 to Jul 28
$161 total
Jul 27 - Jul 28
8.8/10 Excellent! (598 reviews)
"perfect location"

Reviewed on Jun 12, 2025

Oro Verde Manta
See all 187 properties in San Mateo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best San Mateo Vacation Packages

San Mateo Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Eloy Alfaro Intl. Airport (MEC)
Top Sights
Central Bank Museum, Manabí Fisherman Statue and Universidad Laica Eloy Alfaro de Manabi

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Frequently asked questions

How much does a San Mateo vacation package cost?
Offering excellent value package deals from $516 on Expedia, you'll be pleasantly surprised at how much a vacation to San Mateo costs! Expedia's packages make travel planning easier and your savings go further.
What are the cheapest months to go to San Mateo?
November, December and January are great times to search for cheap San Mateo vacation packages. Traveling in quieter periods means you can generally find better prices on flights and accommodations.
How many days is enough for San Mateo?
The ideal duration for your San Mateo vacation depends on what you'd like to see. Usually, a handful of days to a week will give you plenty of time to tick off all the major sights and explore some hidden treasures along the way.
How to find the best San Mateo package deals?
Use Expedia's filter tool to help you find some tempting San Mateo package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your trip for midweek, or browse for San Mateo package deals in the off-season. Play around with your travel dates and you may score even bigger discounts. As a rule of thumb, it's typically best to lock in your vacation package well in advance.
Is it cheaper to book a San Mateo vacation as a package?
An Expedia vacation package could land you significant savings when compared to booking hotels and flights separately. Better still, you can personalize your San Mateo trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a vacation package to San Mateo?
Enjoy incredible discounts by booking your flights ahead of time with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for an impromptu San Mateo escape.
Does Expedia offer Book Now, Pay Later San Mateo vacation packages?
Your San Mateo getaway should be an escape from your busy life, not a reason for money worries. So to allow you a bit more flexibility, we've teamed up with online lender Affirm to offer our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and split up the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.