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Our top choices for San Sisto hotels

The Monteleone

The Monteleone
Monteleone d'Orvieto
10.0 out of 10, Exceptional, (11 reviews)
"What a great find! A beautifully renovated property in a charming area of Umbria. There were many types of rooms to choose from. Our room was spacious and modern yet comfortable. Anna at reception was so friendly and helpful! The buffet breakfast included many choices of pastries, fruit, and hot and cold choices. I highly recommend a stay at the Monteleone!"
United States
Douglas
$130 nightly
The price is $143
May 24 - May 25
Total with taxes and fees
The Monteleone

Borgo Sante Country House

Borgo Sante Country House
Perugia
$127 nightly
The price is $143
Jun 4 - Jun 5
Total with taxes and fees
Borgo Sante Country House

Porsenna Resort

Porsenna Resort
Castiglione del Lago
9.4 out of 10, Exceptional, (46 reviews)
"Fantastic stay!"
United States
Lynn
$113 nightly
The price is $129
May 26 - May 27
Total with taxes and fees
Porsenna Resort

Relais Villa Monte Solare Wellness & SPA

Relais Villa Monte Solare Wellness & SPA
Panicale
9.4 out of 10, Exceptional, (107 reviews)
"Beautiful location! A little remote but perfect for returning to after a day of travel. Dinner at the restaurant was also delicious. "
Canada
Jane
$224 nightly
The price is $246
Jun 11 - Jun 12
Total with taxes and fees
Relais Villa Monte Solare Wellness & SPA

Castello di Monterone

Castello di Monterone
Perugia
9.8 out of 10, Exceptional, (310 reviews)
"Beautiful hotel in restored castle. Staff were kind and welcoming. "
United Kingdom
Stuart
$199 nightly
The price is $227
May 24 - May 25
Total with taxes and fees
Castello di Monterone

Portica 10

Portica 10
Assisi Historic Center
10.0 out of 10, Exceptional, (124 reviews)
"It was lovely to stay there and enjoy the friendly, and lovely services and delicious, fresh breakfast in the morning!! We enjoyed it very much!!!"
United States
ALI
$114 nightly
The price is $132
Jun 23 - Jun 24
Total with taxes and fees
Portica 10

Hotel Monastero Sant'Andrea

Hotel Monastero Sant'Andrea
Assisi Historic Center
9.6 out of 10, Exceptional, (69 reviews)
"Super nice little hotel. Staff was super nice and it’s minutes from cathedral. I will definitely stay there again"
United States
Florania
$100 nightly
The price is $117
May 24 - May 25
Total with taxes and fees
Hotel Monastero Sant'Andrea

Hotel Boutique Castiglione del Lago

Hotel Boutique Castiglione del Lago
4.0 star property
Contrada Castello
9.8 out of 10, Exceptional, (48 reviews)
"Very polite staff!"
Finland
Jari
$108 nightly
The price is $125
May 27 - May 28
Total with taxes and fees
Hotel Boutique Castiglione del Lago

Locanda Stella

Locanda Stella
2.0 star property
Perugia
9.8 out of 10, Exceptional, (35 reviews)
"Really helpful staff "
United Kingdom
Jay
$102 nightly
The price is $117
Jun 18 - Jun 19
Total with taxes and fees
Locanda Stella

Locanda del Molino

Locanda del Molino
4.0 star property
Cortona
9.6 out of 10, Exceptional, (36 reviews)
"family run business with great hospitality and excellent food"
United Kingdom
stefania
$103 nightly
The price is $122
Jun 16 - Jun 17
Total with taxes and fees
Locanda del Molino

Borgo Dei Conti Resort Relais & Chateaux

Borgo Dei Conti Resort Relais & Chateaux
5.0 star property
Perugia
9.4 out of 10, Exceptional, (13 reviews)
"Great place to relax and heal"
United States
Dean
$805 nightly
The price is $894
May 24 - May 25
Total with taxes and fees
Borgo Dei Conti Resort Relais & Chateaux

Hotel Cladan

Hotel Cladan
3.0 star property
Assisi
9.6 out of 10, Exceptional, (69 reviews)
"The staff was very accommodating providing us with wine glasses to enjoy a glass of wine outside. Restaurant Recommendations. Bed was very comfortable, parking provided and great breakfast."
Canada
Sherry
$86 nightly
The price is $102
Jun 7 - Jun 8
Total with taxes and fees
Hotel Cladan

Agriturismo con cucina Il Favaio

Agriturismo con cucina Il Favaio
Paciano
$173 nightly
The price is $192
May 24 - May 25
Total with taxes and fees
Agriturismo con cucina Il Favaio

Lo Spedalicchio

Lo Spedalicchio
3.0 star property
Bastia Umbra
8.8 out of 10, Excellent, (73 reviews)
"Very helpful staff. Would certainly recommend this hotel"
United Kingdom
John
$103 nightly
The price is $118
May 24 - May 25
Total with taxes and fees
Lo Spedalicchio

Le Tre Isole

Le Tre Isole
3.0 star property
Magione
8.0 out of 10, Very Good, (39 reviews)
"Wonderful place to stay. Very nice people, great rooms and facilities. Close to everything nearby: cities, restaurants, beach. Delicious breakfast is presented with kindness and care. We highly recommend staying at Le Tre Isole."
Italy
William
$91 nightly
The price is $105
Jun 15 - Jun 16
Total with taxes and fees
Le Tre Isole

Hotel Ristorante La Bastiglia

Hotel Ristorante La Bastiglia
4.0 star property
Spello
8.0 out of 10, Very Good, (84 reviews)
"Nice place to stay "
Australia
stuart
$94 nightly
The price is $111
May 24 - May 25
Total with taxes and fees
Hotel Ristorante La Bastiglia

Wine Resort La Ghirlanda

Wine Resort La Ghirlanda
Gualdo Cattaneo
9.6 out of 10, Exceptional, (24 reviews)
"Wine tour and view was incredible."
United Kingdom
Jon
$226 nightly
The price is $249
May 24 - May 25
Total with taxes and fees
Wine Resort La Ghirlanda

I Borghi dell'Eremo

I Borghi dell'Eremo
Piegaro
10.0 out of 10, Exceptional, (59 reviews)
"The stay was Amazing "
United States
Jose
$442 nightly
The price is $486
May 25 - May 26
Total with taxes and fees
I Borghi dell'Eremo

Il Castellaro Country House

Il Castellaro Country House
Perugia
9.6 out of 10, Exceptional, (12 reviews)
"Magnificent setting. The owners were very accommodating and make a great breakfast."
Italy
Gregory
$98 nightly
The price is $111
May 26 - May 27
Total with taxes and fees
Il Castellaro Country House

Aethos Hotel Saragano

Aethos Hotel Saragano
Gualdo Cattaneo
9.4 out of 10, Exceptional, (32 reviews)
"Excellent location with beautiful views"
Canada
Nancy
$264 nightly
The price is $290
Jun 21 - Jun 22
Total with taxes and fees
Aethos Hotel Saragano
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is the best area to stay in San Sisto?
For most visitors, the best area to stay in San Sisto is along Via Pievaiola, which is the main thoroughfare connecting the district to Perugia's historic center.

This area is the commercial heart of San Sisto, offering a mix of local shops, eateries, and practical amenities. It's well-connected by public transport to Perugia's main attractions, providing convenience without the higher costs of staying directly in the historic center. Families find this area suitable due to its access to various services and a generally relaxed environment.

Couples looking for a blend of convenience and a slightly more residential feel might consider accommodations a few blocks off Via Pievaiola.
When is the best time to go to San Sisto?
The best time to visit San Sisto is during the shoulder seasons of spring (April to June) and early autumn (September to October).

During these months, the weather is pleasantly mild, with comfortable temperatures ideal for exploring the Umbrian countryside and its historic towns. You'll find fewer crowds compared to the peak summer months, allowing for a more relaxed experience at popular attractions and local restaurants. The landscape is particularly beautiful in spring with blooming wildflowers or in autumn with the changing colors of the vineyards.

For those who enjoy warmer weather and don't mind more visitors, the summer months of July and August offer plenty of sunshine and a lively option. Many local festivals and outdoor events take place during this time, though temperatures can be quite warm, especially in August.

Travelers looking for a quieter, more introspective trip might consider late autumn or winter. While some attractions may have reduced hours, you'll experience a more authentic local pace and potentially find better value on accommodations.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in San Sisto.
How can I save on a San Sisto hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible San Sisto hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a San Sisto hotel?
Prices for hotels in San Sisto often vary, but you can find a great deal from $83 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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