---
title: "Sanlucar de Guadiana Vacation Rentals from $49: Search Short-Term Rentals | Expedia.com"
description: "Find the best deals on Sanlucar de Guadiana vacation rentals with Expedia.com. We offer a huge selection of top vacation homes for rental in Andalusia. Book your next vacation with us!"
canonical: "https://www.expedia.com/Sanlucar-De-Guadiana-Vacation-Rentals.d6211352.Travel-Guide-VacationRentals"
language: en-US
market: US
currency: USD
prices_as_of: 2026-11-12T23:33:12Z
---

Plan your trip

- [Sanlucar de Guadiana Travel Guide](https://www.expedia.com/Sanlucar-De-Guadiana.dx6211352)
- [Hotels in Sanlucar de Guadiana](https://www.expedia.com/Sanlucar-De-Guadiana-Hotels.d6211352.Travel-Guide-Hotels)
- [Flights to Sanlucar de Guadiana](https://www.expedia.com/Cheap-Flights-To-Sanlucar-De-Guadiana.d6211352.Travel-Guide-Flights)
- [Car Rentals in Sanlucar de Guadiana](https://www.expedia.com/Car-Rentals-In-Sanlucar-De-Guadiana.d6211352.Car-Rental-Guide)
- [Sanlucar de Guadiana Vacation Packages](https://www.expedia.com/Sanlucar-De-Guadiana.d6211352.Destination-Travel-Guides)

# Sanlucar de Guadiana Vacation Rentals
![A coastal town with white buildings, a hilltop church, and boats in the foreground.](https://images.trvl-media.com/place/6211352/737dbbb2-fa0e-4705-9fd6-9beafd520d53.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

[Check prices for these dates, December 12 – 13, 2026](https://www.expedia.com/Hotel-Search?regionId=6211352&startDate=2026-12-12&endDate=2026-12-13&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&sort=VACATION%5FRENTAL)

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## Our top choices for Sanlucar de Guadiana vacation rentals

### [1\. Monte da Eirinha](https://www.expedia.com/Mertola-Hotels-Monte-Da-Eirinha.h105953348.Hotel-Information)

![A terrace with a glass table and chairs, a bowl of fruit, and a view of a landscape with trees and a distant hill.](https://images.trvl-media.com/lodging/106000000/105960000/105953400/105953348/febee31c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

- Location: Mertola
- Guest rating: 9.8/10 (Exceptional, 12 reviews)
- Price: $46 nightly, $49 total, Dec 13 - Dec 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals
- Review: Beautiful view!, by Rosario

### [2\. Monte Gordo Hotel Apartamentos & Spa](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Monte-Gordo-Hotel-Apartamentos-Spa.h9699519.Hotel-Information)

![An indoor swimming pool with a water fountain, adjacent to a building with large windows and a well-lit interior.](https://images.trvl-media.com/lodging/10000000/9700000/9699600/9699519/cf601c78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Guest rating: 8.6/10 (Excellent, 198 reviews)
- Price: $71 nightly, $78 total, Nov 14 - Nov 15, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals
- Review: Very well, staffed, friendly, checking great hotel very roomy great value just excellent excellent all over, by Taliman

### [3\. Praia da Lota Resort – Hotel & Apartments](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Praia-Da-Lota-Resort-Apartments.h4925018.Hotel-Information)

![A pathway leading to a pool area surrounded by palm trees and a clear view of the ocean.](https://images.trvl-media.com/lodging/5000000/4930000/4925100/4925018/43dd513a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Guest rating: 8.6/10 (Excellent, 82 reviews)
- Price: $81 nightly, $88 total, Dec 13 - Dec 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals
- Review: Clean comfortable apartment with friendly interactions with all the staff, cleaning staff so helpful, what a wonderful environment that we hope to return to for a longer stay another year, the small towns nearby offered the true Portugese experience and not the hectic tourist push that is unfortunately happening in other areas of the Algarve , by William

### [4\. Apartamentos Turisticos Algoa Praia](https://www.expedia.com/Castro-Marim-Hotels-Apartamentos-Turisticos-Algoa-Praia.h132917276.Hotel-Information)

![A swimming pool with sun loungers, a covered seating area, and a building with multiple balconies.](https://images.trvl-media.com/lodging/133000000/132920000/132917300/132917276/79a13e53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Altura Center
- Guest rating: 9/10 (Wonderful, 4 reviews)
- Price: $66 nightly, $70 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals
- Review: El conserje Tiago está siempre dispuesto a resolverte cualquier duda o contratiempo. La piscina es espectacular y el pueblo muy acogedor Está cerca de la playa., by José

### [5\. Villa Marquez Apartments](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Villa-Marquez-Apartments.h55325097.Hotel-Information)

![A rooftop terrace with white chairs and tables, a white wall with a macrame decoration, and a view of the sea and buildings in the background.](https://images.trvl-media.com/lodging/56000000/55330000/55325100/55325097/759f42bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Guest rating: 10/10 (Exceptional, 12 reviews)
- Price: $86 nightly, $93 total, Nov 16 - Nov 17, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals
- Review: Great!, by Tony

### [6\. El Rompido Resort - The Club by Sunday](https://www.expedia.com/Cartaya-Hotels-Precise-Resort-El-Rompido-The-Club.h1093189.Hotel-Information)

![A resort with a large swimming pool, palm trees, and a view of the ocean.](https://images.trvl-media.com/lodging/2000000/1100000/1093200/1093189/f79ec4be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: El Rompido
- Guest rating: 8.6/10 (Excellent, 526 reviews)
- Price: $99 nightly, $108 total, Dec 13 - Dec 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals
- Review: Room was not ready when we arrived (extra bed and cot). The hotel is call anda have a great pool to relax. Is to park, by Filipe

### [7\. PG - 2A - Studio Standard - Palacete do Guadiana](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-PG-2A-Studio-Standard-Palacete-Do-Guadiana.h132618266.Hotel-Information)

![A red building with a number 219 on the door, cobblestone street, and a tree on the sidewalk.](https://images.trvl-media.com/lodging/133000000/132620000/132618300/132618266/34a5aed9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $184 nightly, $198 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [8\. Algarve Manta Rota Beach by Homing](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Algarve-Manta-Rota-Beach-By-Homing.h95761199.Hotel-Information)

![A balcony with a table set for two, a metal bucket with a bottle, and a plate of grapes.](https://images.trvl-media.com/lodging/96000000/95770000/95761200/95761199/59a62a58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $139 nightly, $143 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [9\. PG - 1D - T2 Superior - Palacete do Guadiana](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Palacete-Do-Guadiana-1D.h118977427.Hotel-Information)

![A dining area with a round table, chairs, and a TV in the background.](https://images.trvl-media.com/lodging/119000000/118980000/118977500/118977427/c46de0db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $197 nightly, $211 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [10\. Monte Gordo Vila Verde by Homing](https://www.expedia.com/Castro-Marim-Hotels-Monte-Gordo-Vila-Verde-By-Homing.h119089504.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/120000000/119090000/119089600/119089504/2251b0f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Castro Marim
- Price: $204 nightly, $207 total, Nov 14 - Nov 15, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [11\. Monte Gordo Beach Ocean View 4 by Homing](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Monte-Gordo-Beach-Ocean-View-4-By-Homing.h112835830.Hotel-Information)

![A dining area with a table set for four, a sofa, and a TV on the wall.](https://images.trvl-media.com/lodging/113000000/112840000/112835900/112835830/79b2f7b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $150 nightly, $155 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [12\. Monte Gordo Beachview 2 by Homing](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Monte-Gordo-Beachview-2-By-Homing.h93171184.Hotel-Information)

![A wooden boardwalk leading to a beach with umbrellas and a lifebuoy.](https://images.trvl-media.com/lodging/94000000/93180000/93171200/93171184/6ffe5671.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $183 nightly, $189 total, Nov 30 - Dec 1, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [13\. Algarve Manta Rota Terrace by Homing](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Algarve-Manta-Rota-Terrace-By-Homing.h112826749.Hotel-Information)

![An outdoor patio with a table set for dining, surrounded by greenery and a white wall.](https://images.trvl-media.com/lodging/113000000/112830000/112826800/112826749/8fa9eac1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $222 nightly, $228 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [14\. Altura Typical House by Homing](https://www.expedia.com/Castro-Marim-Hotels-Altura-Typical-House-By-Homing.h125539973.Hotel-Information)

![A dining table set with breakfast items, a sofa, and a fireplace in a well-lit room.](https://images.trvl-media.com/lodging/126000000/125540000/125540000/125539973/50a2e3ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Altura Center
- Price: $199 nightly, $203 total, Nov 15 - Nov 16, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [15\. PG - 1B - T2 Superior - Palacete do Guadiana](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Palacete-Do-Guadiana-1B.h118977425.Hotel-Information)

![Room](https://images.trvl-media.com/lodging/119000000/118980000/118977500/118977425/4dfd2090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $197 nightly, $211 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [16\. PG - 1EA - Studio Superior - Palacete do Guadiana](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-PG-1EA-Studio-Superior-Palacete-Do-Guadiana.h119269348.Hotel-Information)

![A bedroom with a large bed, a bedside table, a lamp, and a window.](https://images.trvl-media.com/lodging/120000000/119270000/119269400/119269348/31faadc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $158 nightly, $169 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [17\. PG - 1EB - Studio Superior - Palacete do Guadiana](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-PG-1EB-Studio-Superior-Palacete-Do-Guadiana.h119267368.Hotel-Information)

![A balcony with a table, chairs, a bottle of wine, and a book.](https://images.trvl-media.com/lodging/120000000/119270000/119267400/119267368/a3ec7390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $160 nightly, $172 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [18\. PG - 2B - T1 Superior - Palacete do Guadiana](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-PG-2B-T1-Superior-Palacete-Do-Guadiana.h119269345.Hotel-Information)

![A narrow hallway with a staircase leading to a second floor. A fire extinguisher is mounted on the wall.](https://images.trvl-media.com/lodging/120000000/119270000/119269400/119269345/80090102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $149 nightly, $160 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [19\. PG - 1A - T1 Superior - Palacete do Guadiana](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Palacete-Do-Guadiana-1A.h118977273.Hotel-Information)

![Room](https://images.trvl-media.com/lodging/119000000/118980000/118977300/118977273/c6a6c717.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $163 nightly, $176 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

### [20\. PG - 2C - T1 Duplex - Palacete do Guadiana](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-PG-2C-T1-Duplex-Palacete-Do-Guadiana.h119269344.Hotel-Information)

![A hotel room with a bed, a nightstand, a lamp, a window with curtains, and artwork on the wall.](https://images.trvl-media.com/lodging/120000000/119270000/119269400/119269344/88b43ef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Price: $163 nightly, $176 total, Nov 13 - Nov 14, Total with taxes and fees, for Our top choices for Sanlucar de Guadiana vacation rentals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Find vacation rentals that suit your style

[Apartments](https://www.expedia.com/Hotel-Search?destination=Sanlucar%20de%20Guadiana,%20Andalusia,%20Spain&regionId=6211352&latLong=37.473007,-7.466197&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=APARTMENT)

[Aparthotels](https://www.expedia.com/Hotel-Search?destination=Sanlucar%20de%20Guadiana,%20Andalusia,%20Spain&regionId=6211352&latLong=37.473007,-7.466197&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=APART%5FHOTEL)

[Condos](https://www.expedia.com/Hotel-Search?destination=Sanlucar%20de%20Guadiana,%20Andalusia,%20Spain&regionId=6211352&latLong=37.473007,-7.466197&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=CONDO)

[Cottages](https://www.expedia.com/Hotel-Search?destination=Sanlucar%20de%20Guadiana,%20Andalusia,%20Spain&regionId=6211352&latLong=37.473007,-7.466197&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=COTTAGE)

[Villas](https://www.expedia.com/Hotel-Search?destination=Sanlucar%20de%20Guadiana,%20Andalusia,%20Spain&regionId=6211352&latLong=37.473007,-7.466197&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=VILLA)

[Chalets](https://www.expedia.com/Hotel-Search?destination=Sanlucar%20de%20Guadiana,%20Andalusia,%20Spain&regionId=6211352&latLong=37.473007,-7.466197&adults=2&startDate=2026-11-19&d1=2026-11-19&endDate=2026-11-21&d2=2026-11-21&lodging=CHALET)

## Top Sanlucar de Guadiana Hotel Reviews

### [Hotel D'Alcoutim](https://www.expedia.com/Alcoutim-Hotels-Hotel-DAlcoutim.h11963078.Hotel-Information)

![A breakfast table with fruits, a coffee pot, and a view of trees and mountains.](https://images.trvl-media.com/lodging/12000000/11970000/11963100/11963078/2bed68e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Alcoutim
- Review: Muito bom, by mario, September 5, 2025, rated 10/10 Excellent

### [Monte da Eirinha](https://www.expedia.com/Mertola-Hotels-Monte-Da-Eirinha.h105953348.Hotel-Information)

![A terrace with a glass table and chairs, a bowl of fruit, and a view of a landscape with trees and a distant hill.](https://images.trvl-media.com/lodging/106000000/105960000/105953400/105953348/febee31c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: Monte da Eirinha, Mertola, Beja, 7750-212, PT
- Location: Mertola
- Star rating: 3/5
- Guest rating: 9.8/10 (12 reviews)
- Review: Stopping in this house was one of the best experience in our two week trip. I wish we stayed here longer, but we had to return our car next morning in Lisbon. You feel submerged into the Portuguese rural cultural environment. Awesome views around the place, clean air, super quiet, and there's a nice big pool. Better than any 5 star hotel. When we were leaving, some people with Swiss plates came. We'll stop there again for sure!, by VITALI, July 23, 2024, rated 10/10 Excellent

### [Bordoy Grand House Algarve](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Grand-House-Relais-Chateaux.h20358896.Hotel-Information)

![A dining area with wicker chairs and a table set for two, overlooking a body of water.](https://images.trvl-media.com/lodging/21000000/20360000/20358900/20358896/99ce4192.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Review: Everything was 5 star, by sherry, November 8, 2026, rated 10/10 Excellent

### [Beira Rio](https://www.expedia.com/Mertola-Hotels-Beira-Rio.h4739377.Hotel-Information)

![A swimming pool with lounge chairs and an umbrella, surrounded by a fence, with a view of hills in the background.](https://images.trvl-media.com/lodging/5000000/4740000/4739400/4739377/9162d5ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Mertola
- Review: Very large, clean room. Wonderful balcony overlooking a river and ruined medieval fortress. Large bathroom. Difficult on-street parking on a steep road (drag your bags into the hotel). No refrigerator or microwave, but very comfortable and well air-conditioned. Very friend staff. Affordably priced. In a cute little town and well-located. Would happily do it again., by Charles, July 3, 2026, rated 10/10 Excellent

### [Hotel Museu](https://www.expedia.com/Mertola-Hotels-Hotel-Museu.h4761885.Hotel-Information)

![A poolside view with two glasses of a beverage, a tray with a bowl of nuts, and a pair of sunglasses on a chair.](https://images.trvl-media.com/lodging/5000000/4770000/4761900/4761885/e2001027.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Mertola
- Review: The hotel was quiet, clean and perfectly located to enjoy Mertola. Parking was super easy. And the staff were all helpful and pleasant., by Katina, June 30, 2026, rated 10/10 Excellent

### [Villa Marquez](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Villa-Marquez.h36285738.Hotel-Information)

![A balcony with white chairs and a table, potted plants, and a view of buildings and the sea.](https://images.trvl-media.com/lodging/37000000/36290000/36285800/36285738/8c94a58d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Review: Nice clean place with very responsive staff. They were extremely helpful via WhatsApp as I was arriving with a late check in. Cute location, free packing down the block, no issues. Clean room with good working AC. Bathroom was a little run down but completely adequate condition for the price of the room. very nice view from the top balcony off the communal kitchen, you can see the lighthouse. Great value stay, would come again if stopping in the area., by Andrea, May 2, 2026, rated 10/10 Excellent

### [HOTEL DON DIEGO by Ĥ](https://www.expedia.com/Ayamonte-Hotels-HOTEL-DON-DIEGO-By-H.h111522306.Hotel-Information)

![A hotel with a modern facade, multiple flags, and a clear sky.](https://images.trvl-media.com/lodging/112000000/111530000/111522400/111522306/f9ccdf27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Ayamonte
- Review: 👍, by Hafid, October 2, 2026, rated 10/10 Excellent

### [Hotel Apolo](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Hotel-Apolo.h4688392.Hotel-Information)

![A poolside area with sun loungers, umbrellas, and a pool.](https://images.trvl-media.com/lodging/5000000/4690000/4688400/4688392/27f18009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Review: Perfect location when leaving/entering Portugal. Central location with very friendly and helpful staff. Excellent breakfast and spacious clean rooms, by Hermann, October 28, 2026, rated 10/10 Excellent

### [Villa Marquez Apartments](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Villa-Marquez-Apartments.h55325097.Hotel-Information)

![A rooftop terrace with white chairs and tables, a white wall with a macrame decoration, and a view of the sea and buildings in the background.](https://images.trvl-media.com/lodging/56000000/55330000/55325100/55325097/759f42bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: Rua José Barão 68, Vila Real Santo Antonio, Faro, 8900-316, PT
- Location: Vila Real Santo Antonio
- Star rating: 3/5
- Guest rating: 10/10 (12 reviews)
- Review: Great!, by Tony, March 19, 2026, rated 10/10 Excellent

### [The Prime Energize Hotel & Spa](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-The-Prime-Energize.h19809290.Hotel-Information)

![A poolside area with lounge chairs and umbrellas, a clear blue sky, and a building in the background.](https://images.trvl-media.com/lodging/20000000/19810000/19809300/19809290/1cf1a53f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Review: The staff was excellent! The room was large & clean. The pool was clean but awkward to get to. The elevator/lift was very small. Room service was good but slow. Would definitely stay again!!, by Cindy, October 13, 2025, rated 10/10 Excellent

### [Parador de Ayamonte](https://www.expedia.com/Ayamonte-Hotels-Parador-De-Ayamonte.h2525107.Hotel-Information)

![A modern bar area with wooden ceiling, a bar counter, and seating.](https://images.trvl-media.com/lodging/3000000/2530000/2525200/2525107/af0a6092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Ayamonte
- Review: All was good, by Oliver, November 3, 2026, rated 10/10 Excellent

### [Ozadi Altura Beach Resort](https://www.expedia.com/Castro-Marim-Hotels-Eurotel-Altura.h1175090.Hotel-Information)

![A pool with clear water, surrounded by lounge chairs and a pergola with draped fabric.](https://images.trvl-media.com/lodging/2000000/1180000/1175100/1175090/4395a66f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Altura Center
- Review: This hotel is right on the beach and in a delightful seaside village. Every room has a direct view of the ocean. The grounds are nice and private with plenty of room around the pool to relax and not feel crowded. There is a wide variety of restaurants within walking distance of the hotel. The hotel gym, free for guests, helps you enjoy these with less guilt., by Kevin, June 5, 2014, rated 10/10 Excellent

### [Pousada Vila Real Santo Antonio](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Pousada-Vila-Real-Santo-Antonio.h44794756.Hotel-Information)

![A modern outdoor lounge area with stone walls, wicker furniture, and a large vase.](https://images.trvl-media.com/lodging/45000000/44800000/44794800/44794756/2fbdae6e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Review: Beautiful room with warmth and charm great service, wish there was a way to drive up to drop off your luggage., by Antonio, October 20, 2025, rated 10/10 Excellent

### [Monte Rei Golf & Country Club](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Monte-Rei-Golf-Country-Club.h4147985.Hotel-Information)

![A two-story house with a swimming pool in front, surrounded by well-maintained lawns and palm trees.](https://images.trvl-media.com/lodging/5000000/4150000/4148000/4147985/b6247fc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Review: Excellent property in deserted area, by Neville, February 14, 2024, rated 8/10 Good

### [Casas da Quinta de Cima](https://www.expedia.com/Vila-Real-Santo-Antonio-Hotels-Casas-Da-Quinta-De-Cima.h102106749.Hotel-Information)

![A rectangular swimming pool with a tiled edge, surrounded by a grassy lawn and various shrubs.](https://images.trvl-media.com/lodging/103000000/102110000/102106800/102106749/000aa312.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Vila Real Santo Antonio
- Review: Extended our stay in the Algarve region by spending a night here. It was quickly obvious that one night was far too short for this wonderful property. The staff is incredibly attentive, friendly, and helpful. You can’t beat the location. Snacks and breakfast were very tasty. The ultimate place to relax. We hope to be back soon!, by Saundra, October 6, 2026, rated 10/10 Excellent

### [Pensão Agrícola](https://www.expedia.com/Tavira-Hotels-Pensao-Agricola.h101440790.Hotel-Information)

![A modern outdoor seating area with a blue chair and a green rug, a glass door leading to a bedroom with a bed and a nightstand, and a large plant in the background.](https://images.trvl-media.com/lodging/102000000/101450000/101440800/101440790/b894b7a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Tavira
- Review: It was a wonderful experience, we loved every aspect of it! The Service was amazing, the breakfast was fantastic and the staff were very friendly!, by Anas, August 24, 2026, rated 10/10 Excellent

## Find out more about Sanlucar de Guadiana

### Everything you need to know about Sanlucar de Guadiana vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Sanlucar de Guadiana vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Sanlucar de Guadiana vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

### Sanlucar de Guadiana vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Sanlucar de Guadiana. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Sanlucar de Guadiana in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $49 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

### How to find incredible deals on Sanlucar de Guadiana rentals

At Expedia, we put the best Sanlucar de Guadiana vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Sanlucar de Guadiana rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Sanlucar de Guadiana vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Sanlucar de Guadiana. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Frequently Asked Questions

### Can I find a vacation rental in Sanlucar de Guadiana?

Yes, we offer vacation rentals close to the most popular local attractions in Sanlucar de Guadiana, or you can select a secluded option if you want a relaxing place to stay.

### What are some of the best vacation rentals that Sanlucar de Guadiana has to offer?

[This is your dream home](https://www.expedia.com/Ayamonte-Hotels-This-Is-Your-Dream-Home.h46992245.Hotel-Information): This vacation home rental near Sanlucar de Guadiana is located by the ocean and has an outdoor pool, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Make the most of the selection of games in this rental home to help you unwind.

### How many vacation rentals will I find in Sanlucar de Guadiana?

Choose from 4 Expedia vacation rentals in Sanlucar de Guadiana for a memorable vacation.

### What can I see and do in Sanlucar de Guadiana?

While exploring the area, visit family-friendly sights like Parque Zoo Municipal Prudencio Navarro, or get outside and enjoy nature at Molino de El Pintado. In the larger area, you’ll find Iglesia de Sanlucar de Guadiana and Quinta do Vale Golf.

### What are vacation rentals like in Sanlucar de Guadiana?

Vacation rentals are private accommodations you can book for a few days or a quick weekend in Sanlucar de Guadiana. Vacation rentals provide amenities such as patios, hot tubs, and fire pits so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a popular choice for a family getaway.

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