Sant' Ambrogio Vacations
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Your Sant Ambrogio Vacation
Make travel planning simple by locking in a vacation package to Sant Ambrogio. We'll take care of the finer points, so you can concentrate on discovering everything this neighborhood can offer. Your trip to Sant Ambrogio wouldn't be complete without seeing leading attractions nearby such as Cathedral of Santa Maria del Fiore, Ponte Vecchio and Uffizi Gallery. Expedia will help turn your dream Sant Ambrogio vacation into reality, whatever your budget or travel plans.
Price found within the past 48 hours. Click for updated prices.
- Aurum Uffizi
Aug 24 - Aug 30Aurum Uffizi + Flight
Historic Centre of Florence5 nights7.6/10 - Good (1,006 reviews)"Clean and long lasting hot water for shower!"Reviewed May 30, 2026Roundtrip • Boston (BOS) - Florence (FLR)BOS - FLR • 1 stop FLR - BOS • 1 stop$1,468$1,040found 20 hours agoper traveler - Precise Tale Poggio Alla Sala
Jul 1 - Jul 13Precise Tale Poggio Alla Sala + Flight
Montepulciano10 nights9.6/10 - Exceptional (141 reviews)"Beautiful stay for our honeymoon. This is definitely a place to go and feel at peace in the Tuscan countryside. 15 min away from some wineries and 20 min away from Montepulciano. Great balance of feeling relaxed by the spa and pool with some quick getaways. Lastly, the restaurant was beyond excellent. Expensive but well worth it."Reviewed May 23, 2026Roundtrip • New York (JFK) - Ancona (AOI)JFK - AOI • 2 stops AOI - JFK • 2 stops - Park Hotel Villa Ariston
Jul 8 - Jul 15Park Hotel Villa Ariston + Flight
Camaiore6 nights8.8/10 - Excellent (131 reviews)"Highly recommend the Park Villa Ariston! The property is very clean and the staff are amazing. High praise for the breakfast and pool. We hope to return soon"Reviewed May 14, 2026Roundtrip • New York (JFK) - Florence (FLR)JFK - FLR • 1 stop FLR - JFK • 1 stop - L'Andana
Jul 17 - Jul 23L'Andana + Flight
Castiglione della Pescaia5 nights9.4/10 - Exceptional (89 reviews)"This is such a beautiful place in every way and we always love it here. Everything is very special and it is wonderful to spend time in this tranquil setting. "Reviewed October 4, 2025Roundtrip • Boston (BOS) - Rome (FCO)BOS - FCO • 1 stop FCO - BOS • 1 stop$3,065$2,192found 1 day agoper traveler - Aurum Firenze
Jul 23 - Jul 30Aurum Firenze + Flight
Historic Centre of Florence6 nights7.6/10 - Good (1,009 reviews)"The only positive thing about this hotel was location and AC (that we didn't use much, since it wasn't too hot but it worked) Condition is worse than bad; outlet in the bathrooms loose, mold, no shower gel and shampoo, no hand towels, broken closet's door. Don't count on breakfast: disgusting coffe (it should be a crime in Italy), not enough seats; microwaved bacon. My daughter wanted a tee and she was told to boil the water in the microwave. Hostel standard (no offense to any hostel) I looked..."Reviewed May 31, 2026Roundtrip • Boston (BOS) - Florence (FLR)BOS - FLR • 1 stop FLR - BOS • 1 stop$1,765$1,270found 1 day agoper traveler
Where to stay in Sant' Ambrogio
Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
Historic Centre of Florence
10 out of top 10 points of interest in this area
Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.
Sant' Ambrogio Hotel Deals
Hotel Bodoni
Via Martiri del Popolo, 27 Florence FI
$99 nightly
The price is $120 total per night from Jun 28 to Jun 29
$120 total
Jun 28 - Jun 29
Total with taxes and fees
8.2/10 Very Good! (832 reviews)
"Great location, clean and welcoming. It’s easy to get in, just click labeled button and they’ll let you in. Lovely rooftop, breakfast, etc."
Reviewed on May 31, 2026
Hotel Regency
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
$572 nightly
The price is $648 total per night from Jun 7 to Jun 8
$648 total
Jun 7 - Jun 8
Total with taxes and fees
9.4/10 Exceptional! (450 reviews)
"The breakfast was delicious, a wide variety. Service was excellent, quite responsive and attentive staff."
Reviewed on Apr 12, 2026
Hotel Bavaria
Borgo Albizi 26 Florence FI
$105 nightly
The price is $124 total per night from Jul 2 to Jul 3
$124 total
Jul 2 - Jul 3
Total with taxes and fees
8.2/10 Very Good! (438 reviews)
"Je ne me souviens pas que dans la description on parlait d’une salle de bain partagée, à l’extérieur de la chambre. Ceci dit, ce fut très bien. Personnel courtois, hébergement bien entretenu. À savoir: pas d’ascenseur et de quand même pas mal de marches à monter. Une fois sur place, tout est ..."
Reviewed on May 31, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Sant' Ambrogio
Great Synagogue of Florence
Great Synagogue of Florence is just one of the places to see in Florence, so why not enjoy the other things to explore during your travels? Experience the fascinating museums and acclaimed art scene in this vibrant area.
Piazza Massimo D'Azeglio
Find out about the history of Florence when you take a trip to Piazza Massimo D'Azeglio. Stroll along the riverfront or visit the churches in this vibrant area.
Mercato di Sant'Ambrogio
You can browse for the perfect souvenirs at Mercato di Sant'Ambrogio during your trip to Florence. Discover the acclaimed art scene and notable monuments in this vibrant area.
Things to do
City Sightseeing Florence Hop-on Hop-off Bus Tour
$34
per adult
76% of travellers recommend
Small-Group Wine Tasting Experience in the Tuscan Countryside
$105
per adult
98% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
$27
per adult
80% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.