Santa Catarina Vacations from $1,917
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $2,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
The Latest Santa Catarina vacation packages
Price found within the past 48 hours. Click for updated prices.
Don't see what you're looking for?
See all available trips from Columbus to Santa Catarina
View all tripsStay near popular Santa Catarina attractions
Pico São Tomé
9.0/10 (4 reviews)
Commune with nature and explore the great outdoors at Pico São Tomé during your travels in Santa Catarina. Wander the rainforest or discover the area's mountain views.
Santa Catarina Hotel Deals
Pestana São Tomé
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
$213 nightly
$245 total
Nov 1 - Nov 2
Total with taxes and fees
Omali São Tomé – Principe Collection
Praia Lagarto São Tomé
$168 nightly
$199 total
Nov 2 - Nov 3
Total with taxes and fees
9.4/10 Exceptional! (67 reviews)
"Clean and beautiful grounds, but the customer service is lacking!"
Reviewed on Oct 9, 2026
Hotel Central
Rua de Angola São Tomé São Tomé
$47 nightly
$55 total
Nov 15 - Nov 16
Total with taxes and fees
8/10 Very Good! (28 reviews)
"Hotel was good. Walking distance from everything in the city. The staff is helpful. The Wi-Fi is OK but for the money and cleanliness this is the best option in the city."
Reviewed on Aug 29, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Catarina Vacation Packages
More vacations you might like
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
