Santa Cruz Vacations from $333

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Santa Cruz Vacation

When a fun city getaway is calling, answer it with a Santa Cruz vacation package. The neighborhood of Callosa de Segura, which is great for walking, hiking and festivals, makes a fantastic base for your adventures. Want to explore? Murcia Cathedral, Murcia Bull Ring and Terra Natura are among the best places to visit during your trip to Santa Cruz. Your ultimate Santa Cruz vacation is just a few clicks away. Explore hotels, flights and more on Expedia for a trip that's tailored to suit your style.

The Latest Santa Cruz vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Rural el Molino de Felipe
 Ona Hacienda del Alamo Golf Resort
HOTEL MIRADOR DE ALEDO
Ribazos de la Sierra
 Hospedería Bajo el Cejo
Don't see what you're looking for?
See all available trips from Columbus to Santa Cruz
View all trips

What to do in Santa Cruz

Santa Cruz Hotel Deals

Hotel Nelva

Hotel Nelva

4 out of 5
Avenida Primero de Mayo, 5 Murcia Murcia
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $74 total per night from Jul 12 to Jul 13
$74 total
Jul 12 - Jul 13
Total with taxes and fees
9/10 Wonderful! (1,002 reviews)
"Quiet location but only 15 minutes walk into the Old Town and shopping. Great pool although we didn’t use it. Clean room and a very comfortable bed. Excellent breakfast with outside seating option. The onsite underground parking a bonus and cheaper than inner city car parks. If you are driving in ..."

Reviewed on Jun 23, 2026

Hotel Nelva
Barceló Murcia Siete Coronas

Barceló Murcia Siete Coronas

4 out of 5
Paseo de Garay, 5 Murcia Murcia
Fully refundableReserve now, pay when you stay
$79 nightly
The price is $87 total per night from Jul 5 to Jul 6
$87 total
Jul 5 - Jul 6
Total with taxes and fees
8.8/10 Excellent! (879 reviews)
"The room was very comfortable and spacious. Breakfast was delicious and many options."

Reviewed on Jun 30, 2026

Barceló Murcia Siete Coronas
Hotel Torrejoven

Hotel Torrejoven

3 out of 5
Calle Arrecife 7 Torrevieja Alicante
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $94 total per night from Jul 5 to Jul 6
$94 total
Jul 5 - Jul 6
Total with taxes and fees
7.4/10 Good! (218 reviews)
"Hotel is perfect for the budget traveller. Room was very clean, staff were friendly and it's in an ideal location."

Reviewed on Jun 17, 2026

Hotel Torrejoven
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Cruz Vacation Packages

Santa Cruz Essential Information

Language
Spanish
Currency
Euros
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Region de Murcia Intl. Airport (RMU)
Population
2,500
Top Sights
Murcia Cathedral, Terra Natura and Romea Theater

More vacations you might like

Frequently asked questions

How much does a Santa Cruz vacation package cost?
You can grab a vacation package to this popular destination from $333 on Expedia. But how much your vacation to Santa Cruz costs will depend on factors like your hotel choice, season and length of stay.
What are the cheapest months to go to Santa Cruz?
You can typically find lower prices and greater availability in January, March and December. Browse our cheap Santa Cruz vacation packages and you could get some excellent off-season deals.
How many days is enough for Santa Cruz?
The ideal length for your Santa Cruz vacation depends on what you'd like to see. Typically, a handful of days to a week will give you enough time to tick off all the top sights and discover some hidden treasures along the way.
How to find the best Santa Cruz package deals?
Start your search for a Santa Cruz package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Guest rating," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with huge savings. If you don't find the perfect Santa Cruz package deal right away, just play around with your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Santa Cruz adventure underway.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your car rental, flight and hotel into one great-value price and enjoy significant savings. You'll generally land a better deal than booking each component separately. And you'll still get the flexibility to create a personalized Santa Cruz vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Santa Cruz?
If you're planning an impromptu Santa Cruz trip, browse our last-minute deals that can be booked up to a week before you go. Prefer not to wait until the last minute? You can find incredible deals on your flights and hotels by booking ahead.
Does Expedia offer Book Now, Pay Later Santa Cruz vacation packages?
Your Santa Cruz getaway should be an escape from your busy life, not a source of money-related stress. So to allow you a bit more flexibility, we've joined up with online lender Affirm to offer our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and spread the total cost over 3, 6 or 12 months. Plus, there aren't any hidden costs or late payment fees to worry about.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.