Santa Cruz Vacations

Book a Hotel + Flight or Car together to unlock savings

Santa Cruz Hotel Deals

DoubleTree by Hilton Iquitos

DoubleTree by Hilton Iquitos

5 out of 5
Napo 258, Iquitos
Fully refundableReserve now, pay when you stay
$134 nightly
The price is $134 total per night from Oct 8 to Oct 9
$134 total
Oct 8 - Oct 9
8.6/10 Excellent! (350 reviews)
"The hotel is lovely and well-appointed Ted. Like most hiltons I have stayed at this year, this is construction going on. The pool area is nice."

Reviewed on Sep 13, 2025

DoubleTree by Hilton Iquitos
El Dorado Classic Hotel

El Dorado Classic Hotel

3 out of 5
Napo 362, Iquitos, Loreto
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $57 total per night from Oct 5 to Oct 6
$57 total
Oct 5 - Oct 6
8/10 Very Good! (108 reviews)
"Overall a very convenient and clean facility with good service. Great value"

Reviewed on Sep 14, 2025

El Dorado Classic Hotel
Victoria Regia Hotel

Victoria Regia Hotel

3 out of 5
Ricardo Palma 252, Iquitos, Loreto
$65 nightly
The price is $65 total per night from Sep 30 to Oct 1
$65 total
Sep 30 - Oct 1
8.4/10 Very Good! (241 reviews)
"It’s gorgeous"

Reviewed on Sep 18, 2025

Victoria Regia Hotel
See all 212 properties in Loreto Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Santa Cruz vacation package cost?
You'll find cheap prices on Expedia for your Santa Cruz getaway. However, factors like the length of stay, hotel choice and season will influence how much your vacation to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
February, August and December are the best times to search for cheap Santa Cruz vacation packages. Choosing to travel in quieter months means you can generally find reduced prices on accommodations and flights.
How many days is enough for Santa Cruz?
Usually, a handful of days is enough to check out the major attractions during your Santa Cruz vacation. However, if you prefer to have more time to relax or take day tours, think about extending your trip.
How to find the best Santa Cruz package deals?
Bagging a cheap Santa Cruz package deal is easy with Expedia. After you've entered your trip dates and destination under our "Packages" tab, set your budget, add some filters and browse what's available. You can personalize your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Santa Cruz package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll usually land a better deal than booking each component individually. And you'll still get the flexibility to create a customized Santa Cruz vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Santa Cruz?
If you've got your Santa Cruz vacation dates confirmed, book as early as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are ideal for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santa Cruz vacation packages?
If you're like us, you love traveling the world but don't love the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your Santa Cruz break across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.