Santa Cruz Vacations from $293

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The Latest Santa Cruz vacation packages

Price found within the past 48 hours. Click for updated prices.
Taki Tambo Lodge

Taki Tambo Lodge

4.5 out of 5
Price was $364, price is now $293 per person
$293
per person
Jul 29 - Aug 1
found 1 day ago
Roundtrip flight included
Lima (LIM) to Tarapoto (TPP)
10/10 Exceptional! (1 review)
El Resort de Yanashpa - Tarapoto

El Resort de Yanashpa - Tarapoto

4.5 out of 5
Price was $542, price is now $393 per person
$393
per person
Jul 29 - Aug 1
found 1 day ago
Roundtrip flight included
Lima (LIM) to Tarapoto (TPP)
9.4/10 Exceptional! (9 reviews)
“Un lugar que lo tiene todo” El Resort de Yanashpa es un destino único en sí mismo. No hace falta salir para disfrutar, la comida es deliciosa, las experiencias son únicas y el entorno es perfecto para desconectarse y relajarse. Todo está pensado para vivir unas vacaciones realmente increíbles. Definitavamente voy a regresar pronto!!

Reviewed on Oct 16, 2025

Bosque Guardian Lodge

Bosque Guardian Lodge

3.5 out of 5
Price was $842, price is now $634 per person
$634
per person
Jul 29 - Aug 1
found 1 day ago
Roundtrip flight included
Lima (LIM) to Tarapoto (TPP)
9.6/10 Exceptional! (4 reviews)
Hacienda Don Vicente Bungalows - Tarapoto

Hacienda Don Vicente Bungalows - Tarapoto

2.5 out of 5
Price was $397, price is now $318 per person
$318
per person
Jul 29 - Aug 1
found 1 day ago
Roundtrip flight included
Lima (LIM) to Tarapoto (TPP)
9.4/10 Exceptional! (15 reviews)
Tarapoto Wes all booked up so I took a chance on this property it was a nice surprise quite and away from town very clean and the staff was very good I will definitely stay there again the house chicken 🐔 pasta was amazing and on my list to eat again

Reviewed on Apr 30, 2022

Sachakuna Resort

Sachakuna Resort

3 out of 5
Price was $449, price is now $367 per person
$367
per person
Jul 29 - Aug 1
found 1 day ago
Roundtrip flight included
Lima (LIM) to Tarapoto (TPP)
10/10 Exceptional! (2 reviews)
We loved staying in Sachakuna, the cabins are super comfortable and beautiful, the staff are the best, all of them very friendly and always eager to help, if you want to experience peace and connection with nature, this is the place!

Reviewed on Jan 2, 2026

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Santa Cruz Hotel Deals

DoubleTree by Hilton Iquitos

DoubleTree by Hilton Iquitos

5 out of 5
Napo 258 Iquitos
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $119 total per night from Jun 9 to Jun 10
$119 total
Jun 9 - Jun 10
8.8/10 Excellent! (372 reviews)
"Beatiful place for stay in Iquitos"

Reviewed on May 2, 2026

DoubleTree by Hilton Iquitos
Victoria Regia Hotel

Victoria Regia Hotel

4 out of 5
Ricardo Palma 252 Iquitos Loreto
$61 nightly
The price is $61 total per night from May 24 to May 25
$61 total
May 24 - May 25
8.6/10 Excellent! (273 reviews)
"Restaurant is very good. Better than the hotel. Suit room doesnot have a proper window. Thus giving 4 star."

Reviewed on May 15, 2026

Victoria Regia Hotel
Hotel de Turistas Iquitos

Hotel de Turistas Iquitos

3 out of 5
Napo Iquitos Loreto
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $65 total per night from May 25 to May 26
$65 total
May 25 - May 26
8.8/10 Excellent! (39 reviews)
"Resonably priced, Hotel de Touristas is conveniently situated near the Plaza de Armas within walking distance. Our room was a suite overlooking the Malecon and the beautiful Rio beyond. On the fourth floor there is an open air restaurant which offers a panoramic view of a tributary of the Amazon ..."

Reviewed on May 18, 2026

Hotel de Turistas Iquitos
See all 212 properties in Loreto Region
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Cruz Vacation Packages

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Frequently asked questions

How much does a Santa Cruz vacation package cost?
You'll find cheap prices from $293 on Expedia for your Santa Cruz getaway. However, factors like the length of stay, hotel choice and season will influence how much your vacation to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
February, August and December are the best times to search for cheap Santa Cruz vacation packages. Choosing to travel in quieter months means you can generally find reduced prices on accommodations and flights.
How many days is enough for Santa Cruz?
Usually, a handful of days is enough to check out the major attractions during your Santa Cruz vacation. However, if you prefer to have more time to relax or take day tours, think about extending your trip.
How to find the best Santa Cruz package deals?
Bagging a cheap Santa Cruz package deal is easy with Expedia. After you've entered your trip dates and destination under our "Packages" tab, set your budget, add some filters and browse what's available. You can personalize your search by "Property class," "Number of bedrooms," "Traveler experience" and more. Order the results by "Price: low to high" to discover the most wallet-friendly Santa Cruz package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider traveling on a weekday, when prices are typically lower.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll usually land a better deal than booking each component individually. And you'll still get the flexibility to create a customized Santa Cruz vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Santa Cruz?
If you've got your Santa Cruz vacation dates confirmed, book as early as you can to bag some unbeatable deals. With Expedia, you can typically reserve some flights up to one year ahead of time. Prefer spur-of-the-moment adventures? Our last-minute deals are ideal for impromptu escapes.
Does Expedia offer Book Now, Pay Later Santa Cruz vacation packages?
If you're like us, you love traveling the world but don't love the big price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the overall cost of your Santa Cruz break across 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.