Santa Cruz Vacations from $854

Book a Hotel + Flight or Car together to unlock savings

Your Santa Cruz Vacation

Come and discover this interesting city for yourself with a Santa Cruz vacation package. Think about staying in the neighborhood of Downtown Querétaro, which is good for history and culture, and your time here will be nothing short of unforgettable. Santa Rosa de Viterbo Temple, Corregidora Stadium and Aqueduct of Santiago de Querétaro are just some of the many sights you'll want to check out during your trip to Santa Cruz. Stop dreaming and start traveling. Explore the wide range of options on Expedia today and finally put your Santa Cruz vacation plans into motion!

The Latest Santa Cruz Vacation Packages

Price found within the past 48 hours. Click for updated prices.
LA SEÑORIA
La Valise San Miguel de Allende, member of Small Luxury Hotels
Hacienda El Santuario San Miguel de Allende
Casa No Name
Live Aqua San Miguel de Allende

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz

Santa Cruz Hotel Deals

Cinco de Mayo Hotel

Cinco de Mayo Hotel

2.5 out of 5
Calle 5 de Mayo 106 Querétaro QUE
Fully refundableReserve now, pay when you stay
7.4/10 Good! (304 reviews)
great room for the price.

Reviewed on Oct 5, 2025

Cinco de Mayo Hotel
Casa Brunella Hotel Boutique

Casa Brunella Hotel Boutique

3.5 out of 5
Calle Venustiano Carranza No. 37 Querétaro QUE
Fully refundableReserve now, pay when you stay
$67 nightly
The price is $80 total per night from Nov 19 to Nov 20
$80 total
Nov 19 - Nov 20
Total with taxes and fees
9.2/10 Wonderful! (226 reviews)
Unique boutique hotel with eccentric decor and spacious room. Centrally located

Reviewed on Nov 11, 2025

Casa Brunella Hotel Boutique
Hotel Boutique Casa Altamira

Hotel Boutique Casa Altamira

3.5 out of 5
Altamirano No. 9 Interior 1-2 Querétaro QUE
Fully refundableReserve now, pay when you stay
$44 nightly
The price is $53 total per night from Nov 20 to Nov 21
$53 total
Nov 20 - Nov 21
Total with taxes and fees
8.8/10 Excellent! (349 reviews)
Very pretty, nice and comfortable hotel. Very clean and staff very friendly. The only thing what the sewer smell from the shower drain. I put a towel to cover it. Staff very friendly. Very close to everything.

Reviewed on Nov 6, 2025

Hotel Boutique Casa Altamira
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santa Cruz

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.