Santa Cruz Vacations from $674

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Your Santa Cruz Vacation

Come and discover this interesting city for yourself with a Santa Cruz vacation package. Think about staying in the neighborhood of Downtown Querétaro, which is good for history and culture, and your time here will be nothing short of unforgettable. Santa Rosa de Viterbo Temple, Corregidora Stadium and Aqueduct of Santiago de Querétaro are just some of the many sights you'll want to check out during your trip to Santa Cruz. Stop dreaming and start traveling. Explore the wide range of options on Expedia today and finally put your Santa Cruz vacation plans into motion!

The Latest Santa Cruz Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Matian Hotel Boutique

Matian Hotel Boutique

3.5 out of 5
Downtown Tequisquiapan
Save 100% on your flight
per person
Aug 17 - Aug 24
found 15 hours ago
Roundtrip non-stop flight included
Tijuana (TIJ) to Querétaro (QRO)
9.4/10 Exceptional! (247 reviews)
This hotel was a wonderful surprise. We booked it because of the price and location, but it far exceeded our expectations. It has a cozy, familiar atmosphere that makes you feel right at home. With only 13 rooms, each one is exceptionally comfortable and inviting. The pool and dining areas aren't large, but they’re thoughtfully designed and very relaxing. The service was outstanding, and the food was absolutely delicious. I would definitely stay here again! The only downside is that the parking lot has limited space, accommodating only about six cars.

Reviewed on Jun 11, 2025

Pueblo Bonito Vantage San Miguel de Allende

Pueblo Bonito Vantage San Miguel de Allende

4.5 out of 5
Save 100% on your flight
per person
Sep 18 - Sep 23
found 18 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Querétaro (QRO)
No reviews
Casa No Name

Casa No Name

3.5 out of 5
Zona Centro
Save 100% on your flight
per person
Sep 18 - Sep 23
found 1 day ago
Roundtrip non-stop flight included
Denver (DEN) to Querétaro (QRO)
8.6/10 Excellent! (36 reviews)
Really beautiful, friendly staff. I would definitely stay again. Thank you.

Reviewed on Jul 7, 2025

Hacienda El Santuario San Miguel de Allende

Hacienda El Santuario San Miguel de Allende

4 out of 5
Zona Centro
Save 100% on your flight
per person
Sep 18 - Sep 23
found 1 day ago
Roundtrip non-stop flight included
Denver (DEN) to Querétaro (QRO)
9/10 Wonderful! (888 reviews)
Great location, it’s the best street for pictures as the church will be in your background. The rooms are nice and the restaurant had a delicious dinner. The only reason I gave them a 4 instead of 5 is because they arranged my transportation from airport which cost 1900 pesos. On the way back to the airport when I did it myself, it was only 1200 pesos. I can infer they take a cut and that’s not necessary when I’m already paying for my room.

Reviewed on Jul 16, 2025

Live Aqua San Miguel de Allende

Live Aqua San Miguel de Allende

5 out of 5
Colonia Azteca
Save 100% on your flight
per person
Sep 18 - Sep 23
found 18 hours ago
Roundtrip non-stop flight included
Denver (DEN) to Querétaro (QRO)
9.2/10 Wonderful! (785 reviews)
Excellent experience!

Reviewed on Apr 28, 2025

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Mexico which includes mountains and heritage elements

Downtown Querétaro

3 out of top 10 points of interest in this area
4.5/5(362 area reviews)

Downtown Querétaro is known for its abundant dining options, and you can plan a trip to Zenea Garden and Plaza de Armas while you're in town.

Find hotels in Downtown Querétaro

Santa Cruz Hotel Deals

Cinco de Mayo Hotel

Cinco de Mayo Hotel

2.5 out of 5
Calle 5 de Mayo 106, Colonia Centro, Querétaro, QUE
Fully refundableReserve now, pay when you stay
$32 nightly
The price is $38 total per night from Jul 19 to Jul 20
$38 total
Jul 19 - Jul 20
Total includes taxes and fees
7.4/10 Good! (278 reviews)
"Kind of an unbeatable location in the historic center of Queretaro. Simple, clean, decent value."

Reviewed on Jun 20, 2025

Cinco de Mayo Hotel
Casa Brunella Hotel Boutique

Casa Brunella Hotel Boutique

3.5 out of 5
Calle Venustiano Carranza No. 37, Colonia Centro, Querétaro, QUE
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $68 total per night from Jul 22 to Jul 23
$68 total
Jul 22 - Jul 23
Total includes taxes and fees
9.2/10 Wonderful! (202 reviews)
Absolutely amazing Hotel!
"We absolutely love this hotel! From the friendliness of the people working there, to the amazing comfort and size and cleanliness of the rooms, to the amazing free breakfast every morning, it was all wonderful! We loved every second, and will stay there again. Thank you, thank you thank you! Highly ..."

Reviewed on Jul 3, 2025

Casa Brunella Hotel Boutique
HOTEL & SPA DOÑA URRACA QUERETARO

HOTEL & SPA DOÑA URRACA QUERETARO

3 out of 5
117 C. 5 de Mayo La Cruz, Querétaro, QUE
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (51 reviews)
"Centrally located within walking distance to the City Center. The property is nice and the staff very attentive."

Reviewed on Jun 23, 2025

Get rates
HOTEL & SPA DOÑA URRACA QUERETARO
See all 638 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Discover the most popular places to visit in Santa Cruz

Templo y Convento de la Santa Cruz

4.5/5(9 reviews)

Learn about the local history of Querétaro with a stop at Templo y Convento de la Santa Cruz. Visit the churches and shops in this culturally rich area.

Templo y Convento de la Santa Cruz

Arches Viewpoint

You can learn about the history of Querétaro when you stop by Arches Viewpoint. While you're here, you can savor the top-notch restaurants.

Arches Viewpoint

Querétaro Contemporary Art Museum

You can spend time studying the exhibits at Querétaro Contemporary Art Museum in Querétaro. While you're here, you can savor the top-notch restaurants.

Querétaro Contemporary Art Museum

Things to do

Thematic Tour of the Center of Querétaro

Great tour in a vintage Ford-T electric car (replica)

$11
per adult
Great tour in a vintage Ford-T electric car (replica)
Querétaro: Ecological Electric Vehicle Tour

Querétaro: Ecological Electric Vehicle Tour

$15
per adult
Querétaro: Ecological Electric Vehicle Tour
Breakfast in Centro Like the Locals Do

Breakfast in Centro Like the Locals Do

$72
per adult
Breakfast in Centro Like the Locals Do
See all activities in Querétaro
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.