Santa Cruz Vacations from $291

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Santa Cruz Vacation

When you book a Santa Cruz vacation package, you can really enjoy your adventure to the fullest. Discover the best things about this lively city knowing that all the travel planning has been worked out in advance. In the mood to see the sights but not sure where to start? Every trip to Santa Cruz should include Nossa Senhora da Conceicao Church. Check out Expedia's extensive range of travel options and begin planning your ultimate vacation to Santa Cruz today.

The Latest Santa Cruz vacation packages

Price found within the past 48 hours. Click for updated prices.
Residence Vespucci
SERHS Experience Suites
Serhs Natal Grand Hotel & Resort
Casa
Anfitrya - Cobertura Premium 1002
Don't see what you're looking for?
See all available trips from Columbus to Santa Cruz
View all trips

Santa Cruz Hotel Deals

Pousada Pedra Grande

Pousada Pedra Grande

3 out of 5
Alameda Bambu, 25 Vila Rural Holandesa, Zona Rural, Serra de Sao Bento, RN
$99 nightly
The price is $104 total per night from Sep 2 to Sep 3
$104 total
Sep 2 - Sep 3
Total includes taxes and fees
9.2/10 Wonderful! (35 reviews)
Nosso lugar preferido no interior do RN
"Sensacional!!! Energia surreal!!! Nosso lugar preferido no interior do RN. A equipe é nota 10."

Reviewed on Jul 9, 2025

Pousada Pedra Grande
Pousada Vale Encantado

Pousada Vale Encantado

3 out of 5
Sitio Cacimba 15, Monte das Gameleiras, RN
"Foi excelente"

Reviewed on Apr 9, 2022

Pousada Vale Encantado
Pousada Villas da Serra

Pousada Villas da Serra

3 out of 5
Rodovia RN-269, KM83, Serra de Sao Bento, CEP
Excelente estadia!
"O hotel é fantástico. A vista dos quartos é magnífica e faz valer a pena os quilômetros até a chegada ao local. Os quartos são amplos, limpos e muito agradáveis. O banheiro também não foge à regra... A água demora um pouco a esquentar, mas logo depois fica maravilhosa e oferece um banho revigorante... ..."

Reviewed on Mar 5, 2017

Pousada Villas da Serra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More vacations you might like

Frequently asked questions

How much does a Santa Cruz vacation package cost?
You'll find cheap prices from $291 on Expedia for your Santa Cruz break. However, a range of factors like the length of stay, the season and your choice of hotel will influence how much your vacation to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
If you'd like to book a cheap Santa Cruz vacation package, consider planning a trip in February, April and December. You'll usually find better rates on airfares and hotels during these quieter months — perfect for a budget-friendly getaway.
How many days is enough for Santa Cruz?
The ideal duration of your Santa Cruz vacation depends on what you'd like to see. Typically, a handful of days to a week will give you enough time to hit all the leading sights and discover some hidden gems along the way.
How to find the best Santa Cruz package deals?
Start your search for a Santa Cruz package deal by entering your preferred travel dates and destination under our "Packages" tab. Then apply some filters, like "Guest rating" and "Property type," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the ideal Santa Cruz package deal straight away, just tweak your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Santa Cruz adventure off to a flying start.
Is it cheaper to book a Santa Cruz vacation as a package?
Expedia vacation packages are designed to make your money go further. Bundle your flight, car rental and hotel into one great-value price and you could save hundreds of dollars. You'll usually get a better deal than booking each component individually. And you'll still get the flexibility to create a tailored Santa Cruz vacation by choosing your favorite airline, accommodation type and car class.
When to book a vacation package to Santa Cruz?
If you have your Santa Cruz vacation dates confirmed, book early to snap up some outstanding deals. With Expedia, you can often reserve some flights up to one year ahead of time. Prefer spontaneous adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Santa Cruz vacation packages?
If you're anything like us, you love traveling the world but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the overall cost of your Santa Cruz vacation across 3, 6 or 12 months. There are also no late payment fees or hidden costs, so you can snap up great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.