Santa Cruz Vacations from $1,221

Book a Hotel + Flight or Car together to unlock savings

The Latest Santa Cruz vacation packages

Price found within the past 48 hours. Click for updated prices.
La Beliza Resort
Casa Al Mar, Belize
Bella Vista Resort Belize
Ka'ana Resort
Belize Dive Haven
Don't see what you're looking for?
See all available trips from Columbus to Santa Cruz
View all trips

Santa Cruz Hotel Deals

Maya Beach Hotel

Maya Beach Hotel

3 out of 5
Maya Beach Placencia Stan Creek
$116 nightly
The price is $125 total per night from Nov 8 to Nov 9
$125 total
Nov 8 - Nov 9
Total with taxes and fees
9.8/10 Exceptional! (369 reviews)
"It was a beautiful place. The rooms were very close to the ocean and had amazing views. The staff were helpful."

Reviewed on Oct 29, 2026

Maya Beach Hotel
Hopkins Bay Belize, a Muy'Ono Resort

Hopkins Bay Belize, a Muy'Ono Resort

3.5 out of 5
North End, Hopkins Village Hopkins
$186 nightly
The price is $200 total per night from Nov 8 to Nov 9
$200 total
Nov 8 - Nov 9
Total with taxes and fees
9.2/10 Wonderful! (566 reviews)
"Beautiful Pool and Resterant"

Reviewed on Nov 5, 2026

Hopkins Bay Belize, a Muy'Ono Resort
Brisa Oceano Resort

Brisa Oceano Resort

4 out of 5
Placencia Rd. Placencia Stann Creek District
$137 nightly
The price is $152 total per night from Nov 15 to Nov 16
$152 total
Nov 15 - Nov 16
Total with taxes and fees
Brisa Oceano Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Cruz Vacation Packages

More vacations you might like

Frequently asked questions

How to find the best Santa Cruz package deals?
Use Expedia's filter tool to help you find some great Santa Cruz package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your break for midweek, or look for Santa Cruz package deals in the off-peak season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's typically best to book your vacation package as early as possible.
When to book a vacation package to Santa Cruz?
Score amazing discounts by booking your flights early with Expedia. If spontaneity is more your thing, grab one of our last-minute deals for a spur-of-the-moment Santa Cruz break.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.