Title: Santa Isabel Xiloxoxtla Vacation Packages 2026 from $350 | Expedia.com [Santa Isabel Xiloxoxtla Travel Guide](https://expedia.com/Santa-Isabel-Xiloxoxtla.dx553248635640641436)[Hotels in Santa Isabel Xiloxoxtla](https://expedia.com/Santa-Isabel-Xiloxoxtla-Hotels.d553248635640641436.Travel-Guide-Hotels)[Vacation Rentals in Santa Isabel Xiloxoxtla](https://expedia.com/Santa-Isabel-Xiloxoxtla-Vacation-Rentals.d553248635640641436.Travel-Guide-VacationRentals)[Car Rentals in Santa Isabel Xiloxoxtla](https://expedia.com/Car-Rentals-In-Santa-Isabel-Xiloxoxtla.d553248635640641436.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # Santa Isabel Xiloxoxtla Vacations from $350 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Santa Isabel Xiloxoxtla Vacation Our vacation packages to Santa Isabel Xiloxoxtla provide countless opportunities to uncover new sights, sounds and smells. And with all the planning worked out, you can let go and enjoy your city adventure without a care in the world. Fill your days with visits to [Basilica of Ocotlan](https://www.expedia.com/Basilica-Of-Ocotlan-Tlaxcala.d553248621532629923.Vacation-Attraction), [Xicotencatl National Park](https://www.expedia.com/Xicotencatl-National-Park-Tlaxcala.d6113704.Vacation-Attraction) and [Government Palace](https://www.expedia.com/Government-Palace-Tlaxcala.d553248621532976759.Vacation-Attraction), some of the attractions you just have to see during a trip to Santa Isabel Xiloxoxtla. Don't put off your visit to this city any longer. Your perfect Santa Isabel Xiloxoxtla vacation is a couple of clicks away with Expedia. ## The Latest Santa Isabel Xiloxoxtla vacation packages Price found within the past 48 hours. Click for updated prices. ![Capital O Hotel Boutique Las Torres](https://images.trvl-media.com/lodging/91000000/90160000/90151100/90151003/29e0a988_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Capital O Hotel Boutique Las Torres $350 per person Apr 9 - Apr 12 found 9 hours ago Roundtrip flight included Tijuana (TIJ) to Puebla (PBC) 9/10 Wonderful! (62 reviews) Clean room, staff very friendly, very close to attractions points. Reviewed on Feb 21, 2026 ![Casona María](https://images.trvl-media.com/lodging/12000000/11830000/11826400/11826394/10217ef2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Casona María Puebla Historic Center $414 per person Apr 9 - Apr 12 found 9 hours ago Roundtrip flight included Tijuana (TIJ) to Puebla (PBC) 9.4/10 Exceptional! (446 reviews) Clean and good service from the personnel. Recommended. Reviewed on Jan 21, 2025 ![Collection O Al otro lado del rio, Puebla](https://images.trvl-media.com/lodging/10000000/9590000/9583900/9583840/097717ba_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Collection O Al otro lado del rio, Puebla Puebla Historic Center $483 per person Apr 9 - Apr 12 found 9 hours ago Roundtrip flight included Tijuana (TIJ) to Puebla (PBC) 9/10 Wonderful! (199 reviews) Not great for holiday, just fine for quick stay. Parking is not in the property, it is close but it is need it to the staff to open the gate, at night is not ideal. Hotel have several not hotel restaurantes inside the hotel and they are too loud. Again, not for holiday only for quick stay. Reviewed on Oct 14, 2025 ![OYO Hotel Trigos De Oro,San Luis Teolocholco Park](https://images.trvl-media.com/lodging/54000000/53300000/53290600/53290550/676afb24_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### OYO Hotel Trigos De Oro,San Luis Teolocholco Park $353 per person Apr 9 - Apr 12 found 9 hours ago Roundtrip flight included Tijuana (TIJ) to Puebla (PBC) 8.8/10 Excellent! (10 reviews) ![Hotel del Angel, Apizaco](https://images.trvl-media.com/lodging/2000000/1680000/1674800/1674763/9e3e535e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel del Angel, Apizaco San Martin de Porres $459 per person Apr 9 - Apr 12 found 9 hours ago Roundtrip flight included Tijuana (TIJ) to Puebla (PBC) 8.8/10 Excellent! (270 reviews) Room wa a lean and they would come in everyday to make the beds and restock with water bottles. The staff was super nice and helpful and the staff in the restaurant were amazing super attentive and nice Reviewed on Dec 28, 2025 Don't see what you're looking for? See all available trips from Columbus to Santa Isabel Xiloxoxtla [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-27/2026-04-03/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PBC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_553248635640641436) ## Santa Isabel Xiloxoxtla Hotel Deals ![NH Puebla Centro Histórico](https://images.trvl-media.com/lodging/2000000/1280000/1277300/1277213/9811b629_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### NH Puebla Centro Histórico Calle 5 Sur #105, Col. Centro Puebla PUE Fully refundableReserve now, pay when you stay $59 nightly $70 total Mar 1 - Mar 2 Total with taxes and fees 8.6/10 Excellent! (1,542 reviews) This hotel is no longer managed by NH Group and the quality has worsened since last time we were here: - mini fridge in room does not work. We notified it both days but they did not do anything. - Tv is big and new but streaming services do not work - no hair drier - no safety box - no filtering ... Reviewed on Feb 22, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=1277213&PinnedHotelID=1277213&HadPinnedHotel=true®ionId=553248635640641436) ![Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG](https://images.trvl-media.com/lodging/8000000/7670000/7662000/7661913/a98b83a8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Holiday Inn Express Hotel & Suites Puebla Angelopolis by IHG Perseo N. 2502, Col.San Martinito San Andrés Cholula PUE Fully refundableReserve now, pay when you stay $56 nightly $66 total Mar 30 - Mar 31 Total with taxes and fees 9.4/10 Exceptional! (1,030 reviews) Rooms were clean, the breakfast had a good variety and the staff was courteous. Reviewed on Jan 26, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F30%2F2026&endDate=3%2F31%2F2026&selected=7661913&PinnedHotelID=7661913&HadPinnedHotel=true®ionId=553248635640641436) ![Fiesta Inn Puebla Las Animas](https://images.trvl-media.com/lodging/5000000/4960000/4956200/4956147/48ab4eb7_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Fiesta Inn Puebla Las Animas 39 Poniente 3515 Col Las Animas Puebla PUE Fully refundableReserve now, pay when you stay $70 nightly $83 total Mar 1 - Mar 2 Total with taxes and fees [](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=4956147&PinnedHotelID=4956147&HadPinnedHotel=true®ionId=553248635640641436) [See all 658 properties in Santa Isabel Xiloxoxtla](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F28%2F2026&endDate=3%2F1%2F2026®ionId=553248635640641436) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Santa Isabel Xiloxoxtla Vacation Packages ## Santa Isabel Xiloxoxtla Essential Information | Population | 4,400 | | ---------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Top Sights | [Xicotencatl National Park](https://www.expedia.com/Xicotencatl-National-Park-Tlaxcala.d6113704.Vacation-Attraction), [Xicotencatl Theater](https://www.expedia.com/Xicotencatl-Theater-Tlaxcala.d553248621556282381.Vacation-Attraction) and [Government Palace](https://www.expedia.com/Government-Palace-Tlaxcala.d553248621532976759.Vacation-Attraction) | ## More vacations you might like 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Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app