Title: Santa Isabel Xiloxoxtla Vacation Packages 2026 from $416 | Expedia.com

[Santa Isabel Xiloxoxtla Travel Guide](https://expedia.com/Santa-Isabel-Xiloxoxtla.dx553248635640641436)[Hotels in Santa Isabel Xiloxoxtla](https://expedia.com/Santa-Isabel-Xiloxoxtla-Hotels.d553248635640641436.Travel-Guide-Hotels)[Vacation Rentals in Santa Isabel Xiloxoxtla](https://expedia.com/Santa-Isabel-Xiloxoxtla-Vacation-Rentals.d553248635640641436.Travel-Guide-VacationRentals)[Car Rentals in Santa Isabel Xiloxoxtla](https://expedia.com/Car-Rentals-In-Santa-Isabel-Xiloxoxtla.d553248635640641436.Car-Rental-Guide)

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# Santa Isabel Xiloxoxtla Vacations from $416

## Book a Hotel + Flight or Car together to unlock savings

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## Your Santa Isabel Xiloxoxtla Vacation

Our vacation packages to Santa Isabel Xiloxoxtla provide countless opportunities to uncover new sights, sounds and smells. And with all the planning worked out, you can let go and enjoy your city adventure without a care in the world. Fill your days with visits to [Basilica of Ocotlan](https://www.expedia.com/Basilica-Of-Ocotlan-Tlaxcala.d553248621532629923.Vacation-Attraction), [Xicotencatl National Park](https://www.expedia.com/Xicotencatl-National-Park-Tlaxcala.d6113704.Vacation-Attraction) and [Government Palace](https://www.expedia.com/Government-Palace-Tlaxcala.d553248621532976759.Vacation-Attraction), some of the attractions you just have to see during a trip to Santa Isabel Xiloxoxtla. Don't put off your visit to this city any longer. Your perfect Santa Isabel Xiloxoxtla vacation is a couple of clicks away with Expedia.

## The Latest Santa Isabel Xiloxoxtla vacation packages

Price found within the past 48 hours. Click for updated prices.

![Xoxula by Inmense](https://images.trvl-media.com/lodging/13000000/12430000/12425500/12425496/7ce69349_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Xoxula by Inmense

Cholula

$416

per person

Mar 27 - Mar 30

found 1 day ago

Roundtrip non-stop flight included

Tijuana (TIJ) to Puebla (PBC)

9/10 Wonderful! (184 reviews)

Great and friendly staff.

Reviewed on Jan 19, 2026

![Molino de los Reyes ](https://images.trvl-media.com/lodging/82000000/81070000/81065700/81065697/c3f1d63f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Molino de los Reyes 

Save 100% on your flight

$820

per person

Apr 6 - Apr 11

found 1 day ago

Roundtrip non-stop flight included

Los Angeles (LAX) to Puebla (PBC)

8.8/10 Excellent! (8 reviews)

![Hotel Star Express Puebla - Central CAPU](https://images.trvl-media.com/lodging/17000000/16010000/16006900/16006816/b7897358_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Star Express Puebla - Central CAPU

Save 100% on your flight

$422

per person

Apr 13 - Apr 20

found 19 hours ago

Roundtrip flight included

Tijuana (TIJ) to Puebla (PBC)

8.2/10 Very Good! (321 reviews)

It wasn't first class ,But it was an affordable low cost hotel and i really appreciated the free breakfast evey morning. Just bring warm clothing and extra blankets if you are sensitive to the cold. I would stay there again

Reviewed on Jan 19, 2026

![JF Grand Puebla](https://images.trvl-media.com/lodging/37000000/36300000/36292100/36292091/624ea53c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### JF Grand Puebla

La Paz

Save 100% on your flight

$427

per person

Apr 13 - Apr 20

found 19 hours ago

Roundtrip flight included

Tijuana (TIJ) to Puebla (PBC)

9.2/10 Wonderful! (832 reviews)

Buen lugar y buena atención

Reviewed on Jan 24, 2026

![Hotel Marques Del Angel](https://images.trvl-media.com/lodging/22000000/21360000/21357800/21357749/11f3bdec_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Marques Del Angel

Puebla Historic Center

$744

per person

Apr 6 - Apr 11

found 1 day ago

Roundtrip non-stop flight included

Los Angeles (LAX) to Puebla (PBC)

9.4/10 Exceptional! (272 reviews)

Excelentes instalaciones, personal muy amable y el desayuno muy rico.

Reviewed on Nov 19, 2025

Don't see what you're looking for?

See all available trips from Columbus to Santa Isabel Xiloxoxtla

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-03-22/2026-03-29/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PBC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

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## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_553248635640641436)

## Santa Isabel Xiloxoxtla Hotel Deals

![InterContinental Presidente Puebla by IHG](https://images.trvl-media.com/lodging/1000000/50000/46300/46231/78f73717_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

InterContinental Presidente Puebla by IHG

Blvd Hermanos Serdan 141 Puebla PUE

Fully refundable

$87 nightly

$104 total

Mar 1 - Mar 2

Total with taxes and fees

9/10 Wonderful! (1,005 reviews)

\-

Reviewed on Jan 28, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=46231&PinnedHotelID=46231&HadPinnedHotel=true&regionId=553248635640641436)

![NH Puebla Centro Histórico](https://images.trvl-media.com/lodging/2000000/1280000/1277300/1277213/9811b629_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

NH Puebla Centro Histórico

Calle 5 Sur #105, Col. Centro Puebla PUE

Fully refundableReserve now, pay when you stay

$62 nightly

$74 total

Mar 1 - Mar 2

Total with taxes and fees

8.4/10 Very Good! (1,537 reviews)

Clean rooms, great food, awesome staff and nice facilities

Reviewed on Jan 11, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F1%2F2026&endDate=3%2F2%2F2026&selected=1277213&PinnedHotelID=1277213&HadPinnedHotel=true&regionId=553248635640641436)

![Camino Real Puebla Angelopolis](https://images.trvl-media.com/lodging/4000000/3200000/3192000/3191907/b9d7f344_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Camino Real Puebla Angelopolis

Boulevard Atlixcayotl Km 5 San Andrés Cholula PUE

Fully refundableReserve now, pay when you stay

$70 nightly

$84 total

Mar 15 - Mar 16

Total with taxes and fees

8.2/10 Very Good! (2,181 reviews)

Great people, food is good, building is dated. People there are very hepful.

Reviewed on Feb 12, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F15%2F2026&endDate=3%2F16%2F2026&selected=3191907&PinnedHotelID=3191907&HadPinnedHotel=true&regionId=553248635640641436)

[See all 658 properties in Santa Isabel Xiloxoxtla](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=2%2F23%2F2026&endDate=2%2F24%2F2026&regionId=553248635640641436)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best Santa Isabel Xiloxoxtla Vacation Packages

## Santa Isabel Xiloxoxtla Essential Information

| Population | 4,400                                                                                                                                                                                                                                                                                                                                                         |
| ---------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
| Top Sights | [Xicotencatl National Park](https://www.expedia.com/Xicotencatl-National-Park-Tlaxcala.d6113704.Vacation-Attraction), [Xicotencatl Theater](https://www.expedia.com/Xicotencatl-Theater-Tlaxcala.d553248621556282381.Vacation-Attraction) and [Government Palace](https://www.expedia.com/Government-Palace-Tlaxcala.d553248621532976759.Vacation-Attraction) |

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## Frequently asked questions

### How much does a Santa Isabel Xiloxoxtla vacation package cost?

### What are the cheapest months to go to Santa Isabel Xiloxoxtla?

### How many days is enough for Santa Isabel Xiloxoxtla?

### How to find the best Santa Isabel Xiloxoxtla package deals?

### Is it cheaper to book a Santa Isabel Xiloxoxtla vacation as a package?

### When to book a vacation package to Santa Isabel Xiloxoxtla?

### Does Expedia offer Book Now, Pay Later Santa Isabel Xiloxoxtla vacation packages?

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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