Title: Santa Isabel Xiloxoxtla Vacation Packages 2026 from $247 | Expedia.com

[Santa Isabel Xiloxoxtla Travel Guide](https://expedia.com/Santa-Isabel-Xiloxoxtla.dx553248635640641436)[Hotels in Santa Isabel Xiloxoxtla](https://expedia.com/Santa-Isabel-Xiloxoxtla-Hotels.d553248635640641436.Travel-Guide-Hotels)[Vacation Rentals in Santa Isabel Xiloxoxtla](https://expedia.com/Santa-Isabel-Xiloxoxtla-Vacation-Rentals.d553248635640641436.Travel-Guide-VacationRentals)[Car Rentals in Santa Isabel Xiloxoxtla](https://expedia.com/Car-Rentals-In-Santa-Isabel-Xiloxoxtla.d553248635640641436.Car-Rental-Guide)

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# Santa Isabel Xiloxoxtla Vacations from $247

## Book a Hotel + Flight or Car together to unlock savings

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## Your Santa Isabel Xiloxoxtla Vacation

Our vacation packages to Santa Isabel Xiloxoxtla provide countless opportunities to uncover new sights, sounds and smells. And with all the planning worked out, you can let go and enjoy your city adventure without a care in the world. Fill your days with visits to [Basilica of Ocotlan](https://www.expedia.com/Basilica-Of-Ocotlan-Tlaxcala.d553248621532629923.Vacation-Attraction), [Xicotencatl National Park](https://www.expedia.com/Xicotencatl-National-Park-Tlaxcala.d6113704.Vacation-Attraction) and [Government Palace](https://www.expedia.com/Government-Palace-Tlaxcala.d553248621532976759.Vacation-Attraction), some of the attractions you just have to see during a trip to Santa Isabel Xiloxoxtla. Don't put off your visit to this city any longer. Your perfect Santa Isabel Xiloxoxtla vacation is a couple of clicks away with Expedia.

## The Latest Santa Isabel Xiloxoxtla vacation packages

Price found within the past 48 hours. Click for updated prices.

![Capital O Hotel Emperadores Inn, Atlixco](https://images.trvl-media.com/lodging/44000000/43760000/43757900/43757836/a75f07b4_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Capital O Hotel Emperadores Inn, Atlixco

$247

per person

May 3 - May 6

found 10 hours ago

Roundtrip flight included

Tijuana (TIJ) to Puebla (PBC)

7/10 Good! (220 reviews)

Very clean room, the staff members were kind and helpful, a very nice walking distance from the main square. The only thing that I would suggest is to add a fan to the room, no A/C needed byt a fan would be great

Reviewed on Nov 3, 2025

![Grand Fiesta Americana Puebla Angelópolis](https://images.trvl-media.com/lodging/14000000/13210000/13205900/13205808/6f40138f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Grand Fiesta Americana Puebla Angelópolis

Angelópolis

$1,255

per person

Jun 4 - Jun 11

found 21 hours ago

Roundtrip non-stop flight included

Dallas (DFW) to Puebla (PBC)

9.6/10 Exceptional! (1,000 reviews)

Everything was great!

Reviewed on Apr 1, 2026

![Collection O Al otro lado del rio, Puebla](https://images.trvl-media.com/lodging/10000000/9590000/9583900/9583840/daf103bc_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Collection O Al otro lado del rio, Puebla

Puebla Historic Center

$698

per person

May 3 - May 10

found 23 hours ago

Roundtrip non-stop flight included

Chicago (CHI) to Puebla (PBC)

9/10 Wonderful! (220 reviews)

Not great for holiday, just fine for quick stay. Parking is not in the property, it is close but it is need it to the staff to open the gate, at night is not ideal. Hotel have several not hotel restaurantes inside the hotel and they are too loud. Again, not for holiday only for quick stay.

Reviewed on Oct 14, 2025

![Capital O Hotel Boutique Las Torres](https://images.trvl-media.com/lodging/91000000/90160000/90151100/90151003/29e0a988_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Capital O Hotel Boutique Las Torres

$671

per person

May 19 - May 26

found 1 day ago

Roundtrip non-stop flight included

Chicago (CHI) to Puebla (PBC)

9.2/10 Wonderful! (73 reviews)

Clean rooms, really good staff very friendly

Reviewed on Mar 3, 2026

![Hotel Andante](https://images.trvl-media.com/lodging/9000000/8170000/8165800/8165755/ae7cc667_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Hotel Andante

Puebla Historic Center

$775

per person

May 3 - May 10

found 23 hours ago

Roundtrip non-stop flight included

Chicago (CHI) to Puebla (PBC)

9.2/10 Wonderful! (258 reviews)

Cleanliness great staff

Reviewed on Oct 10, 2025

Don't see what you're looking for?

See all available trips from Columbus to Santa Isabel Xiloxoxtla

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-03/2026-05-10/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=PBC&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

## Santa Isabel Xiloxoxtla Hotel Deals

![Holiday Inn Express Puebla by IHG](https://images.trvl-media.com/lodging/1000000/1000000/990300/990253/1c0b91c4_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Holiday Inn Express Puebla by IHG

Blvd. Hermanos Serdan 45 Puebla PUE

Fully refundable

$58 nightly

$68 total

Apr 5 - Apr 6

Total with taxes and fees

9.4/10 Exceptional! (1,761 reviews)

Everything perfect

Reviewed on Mar 22, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=990253&PinnedHotelID=990253&HadPinnedHotel=true&regionId=553248635640641436)

![Camino Real Puebla Angelopolis](https://images.trvl-media.com/lodging/4000000/3200000/3192000/3191907/474516f8_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Camino Real Puebla Angelopolis

Boulevard Atlixcayotl Km 5 San Andrés Cholula PUE

Fully refundableReserve now, pay when you stay

$52 nightly

$62 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=3191907&PinnedHotelID=3191907&HadPinnedHotel=true&regionId=553248635640641436)

![InterContinental Presidente Puebla by IHG](https://images.trvl-media.com/lodging/1000000/50000/46300/46231/1967178c_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

InterContinental Presidente Puebla by IHG

Blvd Hermanos Serdan 141 Puebla PUE

Fully refundable

$93 nightly

$110 total

Apr 5 - Apr 6

Total with taxes and fees

9/10 Wonderful! (1,001 reviews)

Clean room, beautiful pool, attentive staff

Reviewed on Mar 16, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=46231&PinnedHotelID=46231&HadPinnedHotel=true&regionId=553248635640641436)

[See all 658 properties in Santa Isabel Xiloxoxtla](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=4%2F4%2F2026&endDate=4%2F5%2F2026&regionId=553248635640641436)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best Santa Isabel Xiloxoxtla Vacation Packages

## Santa Isabel Xiloxoxtla Essential Information

| Population | 4,400                                                                                                                                                                                                                                                                                                                                                         |
| ---------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- |
| Top Sights | [Xicotencatl National Park](https://www.expedia.com/Xicotencatl-National-Park-Tlaxcala.d6113704.Vacation-Attraction), [Xicotencatl Theater](https://www.expedia.com/Xicotencatl-Theater-Tlaxcala.d553248621556282381.Vacation-Attraction) and [Government Palace](https://www.expedia.com/Government-Palace-Tlaxcala.d553248621532976759.Vacation-Attraction) |

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## Frequently asked questions

### How much does a Santa Isabel Xiloxoxtla vacation package cost?

### What are the cheapest months to go to Santa Isabel Xiloxoxtla?

### How many days is enough for Santa Isabel Xiloxoxtla?

### How to find the best Santa Isabel Xiloxoxtla package deals?

### Is it cheaper to book a Santa Isabel Xiloxoxtla vacation as a package?

### When to book a vacation package to Santa Isabel Xiloxoxtla?

### Does Expedia offer Book Now, Pay Later Santa Isabel Xiloxoxtla vacation packages?

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

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