Title: Santa Isabel Vacation Packages 2026 from $720 | Expedia.com

[Santa Isabel Travel Guide](https://expedia.com/Santa-Isabel.dx6351992)[Hotels in Santa Isabel](https://expedia.com/Santa-Isabel-Hotels.d6351992.Travel-Guide-Hotels)[Vacation Rentals in Santa Isabel](https://expedia.com/Santa-Isabel-Vacation-Rentals.d6351992.Travel-Guide-VacationRentals)[Flights to Santa Isabel](https://expedia.com/Cheap-Flights-To-Santa-Isabel.d6351992.Travel-Guide-Flights)[Car Rentals in Santa Isabel](https://expedia.com/Car-Rentals-In-Santa-Isabel.d6351992.Car-Rental-Guide)

![](https://images.trvl-media.com/place/6351992/0b01a9a5-bdad-4efb-a397-7695cdf68922.jpg?impolicy=fcrop&w=1200&h=300&q=medium)

# Santa Isabel Vacations from $720

## Book a Hotel + Flight or Car together to unlock savings

- ##  
Plan, book, travel with confidence
- ###  
Better together  
Save up to $1,045 when you book a flight and hotel together\*
- ###  
Find the right fit  
With over 300,000 hotels worldwide, it's easy to create a perfect package
- ###  
Rest easy  
Plan, book, and manage your trip all in one place

## The Latest Santa Isabel vacation packages

Price found within the past 48 hours. Click for updated prices.

![Platina 220](https://images.trvl-media.com/lodging/110000000/109420000/109413300/109413264/52ccd896_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Platina 220

Tatuape

$720

per person

May 5 - May 12

found 6 hours ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to São Paulo (GRU)

9/10 Wonderful! (2 reviews)

![Intercity Tatuapé](https://images.trvl-media.com/lodging/88000000/87140000/87139000/87138965/b936d05d_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Intercity Tatuapé

Tatuape

$818

per person

May 5 - May 12

found 6 hours ago

Roundtrip non-stop flight included

Newark Liberty Intl. Airport (EWR) to São Paulo (GRU)

9.2/10 Wonderful! (563 reviews)

Very nice hotel and friendly staff. Great breakfast. Highly recommend.

Reviewed on Mar 2, 2026

![You Stay at Vila Olimpia - ITC](https://images.trvl-media.com/lodging/36000000/35740000/35733300/35733258/f16af325_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### You Stay at Vila Olimpia - ITC

Itaim Bibi

$1,029

per person

May 10 - May 16

found 1 day ago

Roundtrip non-stop flight included

Los Angeles (LAX) to São Paulo (GRU)

9.2/10 Wonderful! (194 reviews)

A dream stay for our family of four and such a steal! This property was truly a dream come true for our family of four two adults and two young girls. The space was spotless, beautifully arranged, and incredibly comfortable. The beds were cozy and gave us great rest after long days out. The amenities were outstanding: from the spacious layout to the stunning views and peaceful atmosphere. Even though we don’t speak Portuguese, the staff was exceptionally kind and helpful. We felt welcome, safe, and taken care of the entire time it was an absolute honor to stay here. There were great food options around, and we appreciated the local tips. And the price? Let me tell you a total bargain for the quality and experience. We would love to return and recommend it 100% to anyone traveling with kids or looking for comfort, beauty, and value.

Reviewed on Aug 5, 2025

![Grand Mercure Sao Paulo Ibirapuera](https://images.trvl-media.com/lodging/1000000/450000/444100/444043/a2c11785_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Grand Mercure Sao Paulo Ibirapuera

Vila Mariana

$1,152

per person

May 10 - May 16

found 1 day ago

Roundtrip non-stop flight included

Los Angeles (LAX) to São Paulo (GRU)

8.8/10 Excellent! (635 reviews)

The room was fantastic, the staff was amazing, the people that i went with really enjoyed the stay there. Breakfast was amazing there, the room service food was great.

Reviewed on Feb 14, 2026

![Palacio Tangara, Oetker Hotels](https://images.trvl-media.com/lodging/16000000/15910000/15902900/15902804/b19e4325_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

### Palacio Tangara, Oetker Hotels

Vila Andrade

Save 100% on your flight

$2,453

per person

May 10 - May 16

found 1 day ago

Roundtrip non-stop flight included

Los Angeles (LAX) to São Paulo (GRU)

9.6/10 Exceptional! (1,002 reviews)

Wonderful experience

Reviewed on Nov 2, 2025

Don't see what you're looking for?

See all available trips from Columbus to Santa Isabel

[View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-03/2026-04-10/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=SAO&NumRoom=1&NumAdult=2&NumChild=0&paandie=true)

![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh)

## 

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

[Book now](https://expedia.com/deals?rfrr=PKG_SPRING_PROMO_6351992)

### Discover the most popular places to visit in Santa Isabel

![Paulista Avenue featuring heritage architecture](https://images.trvl-media.com/place/6158713/56fc178c-179e-4b67-a0e8-04d275c51404.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Paulista Avenue

4.5/5(188 reviews)

See the financial and cultural heart of one of South America’s busiest cities before unwinding in a bar full of local business people at the end of the day.

[](https://expedia.com/Paulista-Avenue-Jardim-Paulista.d6158713.Vacation-Attraction)

![Vista aérea do autódromo de Interlagos. São Paulo.](https://images.trvl-media.com/place/6161103/a14ac6a9-d609-4ee7-8c16-529606ba151b.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Interlagos Race Track

4.5/5(14 reviews)

Interlagos Race Track is one of the more well-known attractions to visit during your trip to São Paulo. Experience the art scene and museums in this culturally rich area. 

[](https://expedia.com/Interlagos-Race-Track-Interlagos.d6161103.Vacation-Attraction)

![SaoPaulo_AllianzPark_553248621561096527_07](https://images.trvl-media.com/place/553248621561096527/1a97f7b1-184c-44fb-8840-f58a75c5199d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Allianz Parque

4/5(29 reviews)

Catch an event at Allianz Parque during your trip to São Paulo. While in this culturally rich area, find time to visit its shops. 

[](https://expedia.com/Allianz-Parque-Barra-Funda.d553248621561096527.Vacation-Attraction)

### What to do in Santa Isabel

![São Paulo: Main City Sights in 7 Hours – Shared Group Tour](https://mediaim.expedia.com/localexpert/44547746/36a13134-9521-49bc-b525-214ffdd515b9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### São Paulo: Main City Sights in 7 Hours – Shared Group Tour

$83

per adult

**98%** of travellers recommend

[](https://expedia.com/things-to-do/sao-paulo-main-city-sights-in-7-hours-shared-group-tour.a44547746.activity-details)

![Downtown São Paulo's Epic History: A Self-Guided Audio Tour](https://mediaim.expedia.com/localexpert/4342169/e0e8c6de-155f-45a8-beda-b450a745f10e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Downtown São Paulo's Epic History: A Self-Guided Audio Tour

$6

per adult

**100%** of travellers recommend

[](https://expedia.com/things-to-do/downtown-sao-paulos-epic-history-a-self-guided-audio-tour.a4342169.activity-details)

![Sao Paulo: Downtown-Center Walking Tour | 2 Hours](https://mediaim.expedia.com/localexpert/4753384/27686aa0-0cb5-40aa-afb1-285da3bf5916.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh)

#### Sao Paulo: Downtown-Center Walking Tour | 2 Hours - English

$36

per adult

[](https://expedia.com/things-to-do/sao-paulo-downtown-center-walking-tour-2-hours-english.a4753384.activity-details)

[See all activities in Santa Isabel](https://expedia.com/things-to-do/search?rid=6351992)

## Santa Isabel Hotel Deals

![Hampton by Hilton Guarulhos Airport](https://images.trvl-media.com/lodging/2000000/1810000/1807500/1807453/89c5bad4_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Hampton by Hilton Guarulhos Airport

Rua Pedro De Toledo, 1000 Guarulhos 

Fully refundableReserve now, pay when you stay

$91 nightly

$96 total

Mar 7 - Mar 8

Total with taxes and fees

8.8/10 Excellent! (2,452 reviews)

The breakfast was excellent, the location waسs good, the staff were friendly, but the room was bad and the towels were in shabby condition.

Reviewed on Mar 1, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F7%2F2026&endDate=3%2F8%2F2026&selected=1807453&PinnedHotelID=1807453&HadPinnedHotel=true&regionId=6351992)

![Comfort Hotel Guarulhos - Aeroporto](https://images.trvl-media.com/lodging/62000000/61610000/61608900/61608834/3d7b64a0_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Comfort Hotel Guarulhos - Aeroporto

R. Pedro de Toledo 977 Guarulhos SP

Fully refundableReserve now, pay when you stay

$99 nightly

$104 total

Mar 29 - Mar 30

Total with taxes and fees

8.6/10 Excellent! (1,505 reviews)

The room was really big and very clean, the staff was excellent. Well worth the price. We unfortunately only had 6 hours there as it was just because we landed in the evening and the next flight was in the morning. But they have everything you want there. Well worth the price

Reviewed on Mar 1, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F29%2F2026&endDate=3%2F30%2F2026&selected=61608834&PinnedHotelID=61608834&HadPinnedHotel=true&regionId=6351992)

![Bristol International Airport Hotel](https://images.trvl-media.com/lodging/1000000/800000/794200/794182/5a27133a_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Bristol International Airport Hotel

Rua José de Andrade, 63 Guarulhos SP

Fully refundableReserve now, pay when you stay

$80 nightly

$84 total

Mar 27 - Mar 28

Total with taxes and fees

9/10 Wonderful! (1,925 reviews)

Breakfast product quality

Reviewed on Feb 28, 2026

[](https://expedia.com/Hotel-Search?startDate=3%2F27%2F2026&endDate=3%2F28%2F2026&selected=794182&PinnedHotelID=794182&HadPinnedHotel=true&regionId=6351992)

[See all 788 properties in Santa Isabel](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F4%2F2026&endDate=3%2F5%2F2026&regionId=6351992)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Find the Best Santa Isabel Vacation Packages

## Santa Isabel Essential Information

| Language        | Portuguese                                                    |
| --------------- | ------------------------------------------------------------- |
| Currency        | Brazilian reals                                               |
| Local Welcome   | Olá                                                           |
| Local Goodbye   | Adeus                                                         |
| Closest Airport | Guarulhos - Governor Andre Franco Montoro Intl. Airport (GRU) |
| Population      | 33,700                                                        |
| Max Temp Winter | 70ºF                                                          |
| Max Temp Summer | 80ºF                                                          |

## More vacations you might like

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

All Inclusive Vacations

[](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Beach Vacations

[](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Kid Friendly Vacations

[](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Golf Vacations

[](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Luxury Vacations

[](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Romantic Vacations

[](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Ski Vacations

[](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click)

![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

LGBTQ Friendly Vacations

[](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adventure Vacations

[](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click)

![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Where to go when

[](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Honeymoon Vacations

[](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Mountain Vacations

[](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Fishing Vacations

[](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Adults Only Vacations

[](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Waterpark Vacations

[](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Scuba Diving Vacations

[](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Yoga Vacations

[](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Cheap Vacations

[](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click)

![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh)

Solo Vacations

[](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click)

## Frequently asked questions

### How much does a Santa Isabel vacation package cost?

### What are the cheapest months to go to Santa Isabel?

### How many days is enough for Santa Isabel?

### How to find the best Santa Isabel package deals?

### Is it cheaper to book a Santa Isabel vacation as a package?

### When to book a vacation package to Santa Isabel?

### Does Expedia offer Book Now, Pay Later Santa Isabel vacation packages?

\* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg)

## Go further with the Expedia app

Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app