Santa Lucia Vacations from $650

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Your Santa Lucia Vacation

Take the stress and hassle out of planning your next break by booking a Santa Lucia vacation package. Immerse yourself in the sounds and sights of this wonderful neighborhood and enjoy everything it has to offer. Your trip to Santa Lucia wouldn't be complete without seeing popular attractions nearby such as Cathedral of Syracuse, Temple of Apollo and Museo Archeologico Regionale Paolo Orsi. Don't just dream it — take action! Secure your ideal Santa Lucia vacation with Expedia and enjoy traveling your way.

The Latest Santa Lucia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Bed and Breakfast Opera

Bed and Breakfast Opera

3 out of 5
Catania City Centre
Price was $830, price is now $650 per person
$650
per person
Jan 19 - Jan 24
found 1 day ago
Roundtrip flight included
Los Angeles (QLA) to Catania (CTA)
8/10 Very Good! (73 reviews)
This accommodation had a great location, central and close to great restaurants and sight seeing. The staff & service was excellent. I did not have the breakfast so I can't speak to that. The room quality was average. Needs an update/refresh. Street noise was very loud on busy street and difficult to sleep soundly.

Reviewed on Sep 25, 2025

Hotiday Taormina Mare

Hotiday Taormina Mare

4 out of 5
Spisone
Price was $2,052, price is now $1,552 per person
$1,552
per person
Jan 19 - Jan 24
found 1 day ago
Roundtrip flight included
Los Angeles (QLA) to Catania (CTA)
8.4/10 Very Good! (7 reviews)
It was a beautiful area, near the beach and cable car which takes you up to the city. The only issue I had was the mattress was really overly firm for my liking, but that was my preference. The breakfast was wonderful and sitting on the veranda and looking over the water completed the visit.

Reviewed on Sep 22, 2025

Palazzo Sangiorgio

Palazzo Sangiorgio

5 out of 5
Catania City Centre
Price was $1,160, price is now $946 per person
$946
per person
Jan 27 - Jan 30
found 1 day ago
Roundtrip flight included
Boston (BOS) to Catania (CTA)
9.8/10 Exceptional! (154 reviews)
Was a wonderful hotel. Nice gift upon check in. Beds are firm

Reviewed on Oct 11, 2025

Mareneve Resort

Mareneve Resort

4 out of 5
Price was $851, price is now $723 per person
$723
per person
Jan 27 - Jan 30
found 1 day ago
Roundtrip flight included
Boston (BOS) to Catania (CTA)
8.4/10 Very Good! (62 reviews)
Hotel was well located for our visit to Etna. It was comfortable and clean. Parking on site with a good restaurant.

Reviewed on Jun 25, 2025

Duomo Suites & Spa

Duomo Suites & Spa

4 out of 5
Catania City Centre
Price was $912, price is now $787 per person
$787
per person
Jan 27 - Jan 30
found 1 day ago
Roundtrip flight included
Boston (BOS) to Catania (CTA)
9.2/10 Wonderful! (417 reviews)
Excellent location to bus terminal area and sights. Friendly and helpful staff.

Reviewed on Nov 30, 2025

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most. Learn more about Santa Lucia
Temple of Apollo featuring a ruin and heritage elements

Ortigia

4 out of top 10 points of interest in this area
4.5/5(147 area reviews)

The historic heart of Syracuse is dotted with churches and atmospheric piazzas, where visitors enjoy sweeping sea views while dining at gourmet restaurants.

Find hotels in Ortigia

Santa Lucia Hotel Deals

Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri

4 out of 5
42 Via Malta Syracuse SR
Fully refundableReserve now, pay when you stay
$113 nightly
The price is $129 total per night from Dec 16 to Dec 17
$129 total
Dec 16 - Dec 17
Total with taxes and fees
8.8/10 Excellent! (38 reviews)
Excelente ubicación!!!

Reviewed on Oct 10, 2025

Hotel Palazzo Cavalieri
Grande Albergo Alfeo

Grande Albergo Alfeo

4 out of 5
Via Nino Bixio 5 Syracuse SR
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $106 total per night from Dec 18 to Dec 19
$106 total
Dec 18 - Dec 19
Total with taxes and fees
8.6/10 Excellent! (640 reviews)
Good front desk staff, welcoming breakfast staff, clean room and good area for walking to attractions.

Reviewed on Dec 2, 2025

Grande Albergo Alfeo
Caportigia Boutique Hotel

Caportigia Boutique Hotel

5 out of 5
Viale Montedoro 76 Syracuse SR
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $148 total per night from Dec 14 to Dec 15
$148 total
Dec 14 - Dec 15
Total with taxes and fees
9.2/10 Wonderful! (255 reviews)
Nothing standout, everything is expected as a four star place. However I was surprised breakfast is not included. It is $15 per person which is the only hotel in my trip that doesn’t provide free breakfast.

Reviewed on Oct 31, 2025

Caportigia Boutique Hotel
See all 3,865 properties in Santa Lucia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Santa Lucia

Porto Piccolo

4.5/5(11 reviews)

Explore the waterfront in Syracuse with a trip to Porto Piccolo. Wander the seaside in this culturally rich area.

Porto Piccolo

Syracuse Forum Ruins

You can learn about the history of Syracuse with a trip to Syracuse Forum Ruins. Wander the beautiful beaches and seaside in this culturally rich area.

Syracuse Forum Ruins

Madonna delle Lacrime

4/5(1 review)

You can study the exhibits at Madonna delle Lacrime, a museum with a story of its own, during your trip to Syracuse. Wander the seaside in this culturally rich area.

Madonna delle Lacrime

Things to do

Siracusa: Ortygia Island Boat Tour with Grotto Visit

Siracusa: Ortygia Island Boat Tour with Grotto Visit

$29
per adult
Siracusa: Ortygia Island Boat Tour with Grotto Visit
Syracuse: Boat Tour with Captain Mirko, Snorkeling & Caves

Syracuse: Boat Tour with Captain Mirko, Snorkeling & Caves

$35
per adult
Syracuse: Boat Tour with Captain Mirko, Snorkeling & Caves
Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat

Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat

$46
per adult
Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat
See all activities in Syracuse
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.