Santa Lucia Vacations from $1,007

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Your Santa Lucia Vacation

Take the stress and hassle out of planning your next break by booking a Santa Lucia vacation package. Immerse yourself in the sounds and sights of this wonderful neighborhood and enjoy everything it has to offer. Your trip to Santa Lucia wouldn't be complete without seeing popular attractions nearby such as Cathedral of Syracuse, Temple of Apollo and Museo Archeologico Regionale Paolo Orsi. Don't just dream it — take action! Secure your ideal Santa Lucia vacation with Expedia and enjoy traveling your way.

The Latest Santa Lucia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Elios

Hotel Elios

$1,007
per person
Dec 2 - Dec 8
found 21 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Catania (CTA)
7/10 Good! (30 reviews)
The room was comfortable as was the bed. The breakfast was wonderful with plenty of options and the view from the outdoor terrace was beautiful. We would stay here again.

Reviewed on Oct 9, 2026

Villa Conrad by Hotel Metropole Taormina

Villa Conrad by Hotel Metropole Taormina

Taormina City Centre
Save 100% on your flight
$1,625
per person
Dec 2 - Dec 8
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Catania (CTA)
9.4/10 Exceptional! (33 reviews)
Hotel Continental

Hotel Continental

Taormina City Centre
$1,053
per person
Dec 2 - Dec 8
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Catania (CTA)
9.2/10 Wonderful! (686 reviews)
Eurostars Monte Tauro

Eurostars Monte Tauro

$1,032
per person
Dec 2 - Dec 8
found 23 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Catania (CTA)
8.4/10 Very Good! (496 reviews)
The best thing about this place is the view. Totally incomparable. The facilities themselves could use some TLC - they are making the transition from “gently used” and slightly dingy to rundown. Also, the rooms are infested with ants.

Reviewed on Oct 12, 2026

Hotel Villa Paradiso

Hotel Villa Paradiso

Taormina City Centre
$1,951
per person
Jan 5 - Jan 9
found 8 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Catania (CTA)
9.6/10 Exceptional! (447 reviews)
Great location in the heart of the historical district, next door to a beautiful city park and walking distance to everything. Views from two balconies were spectacular. Older hotel, lots of antique furnishings and large rooms. I would recommend.

Reviewed on Oct 15, 2026

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most. Learn more about Santa Lucia
Ancient ruins with stone columns and a building with green shutters in the background.

Ortigia

4 out of top 10 points of interest in this area

The historic heart of Syracuse is dotted with churches and atmospheric piazzas, where visitors enjoy sweeping sea views while dining at gourmet restaurants.

Find hotels in Ortigia
Ancient ruins with stone steps and walls, surrounded by trees.

Neapolis

3 out of top 10 points of interest in this area

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Find hotels in Neapolis
An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Grottasanta

1 out of top 10 points of interest in this area

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Find hotels in Grottasanta
An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Find hotels in Tiche
An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Find hotels in Acradina

Santa Lucia Hotel Deals

Grande Albergo Alfeo

Grande Albergo Alfeo

Via Nino Bixio 5 Syracuse SR
$63 nightly
$72 total
Nov 16 - Nov 17
Total with taxes and fees
8.6/10 Excellent! (708 reviews)
"We enjoyed our stay"

Reviewed on Sep 29, 2026

Grande Albergo Alfeo
Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri

42 Via Malta Syracuse SR
Fully refundableReserve now, pay when you stay
$89 nightly
$101 total
Nov 2 - Nov 3
Total with taxes and fees
9/10 Wonderful! (49 reviews)
"Very responsive staff that helped me organize transportation to and from the airport, accommodation for my baby, and a surprise welcome for my wife’s birthday. Amazing location just outside Ortigia, I honestly preferred staying there than on the island. Highly recommended."

Reviewed on Oct 1, 2026

Hotel Palazzo Cavalieri
Caportigia Boutique Hotel

Caportigia Boutique Hotel

Viale Montedoro 76 Syracuse SR
Fully refundableReserve now, pay when you stay
$138 nightly
$163 total
Nov 16 - Nov 17
Total with taxes and fees
9.2/10 Wonderful! (300 reviews)
"Overall the hotel was very nice and in perfect location. We would definitely stay again. Some items they could improve. The reading lights above bed did not work and there was no other source of light except the huge lights for the entire room. The shower floor was super super super slippery. Both ..."

Reviewed on Sep 28, 2026

Caportigia Boutique Hotel
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Stay near popular Santa Lucia attractions

Porto Piccolo

8.8/10 (189 reviews)
Explore the waterfront in Syracuse with a trip to Porto Piccolo. Wander the seaside in this culturally rich area.
See properties

Syracuse Forum Ruins

You can learn about the history of Syracuse with a trip to Syracuse Forum Ruins. Wander the beautiful beaches and seaside in this culturally rich area.
See properties

Santa Lucia Bridge

8.8/10 (13 reviews)
Santa Lucia Bridge is just one of the places to see in Syracuse, so why not enjoy the other things to explore during your travels? Discover the museums and monuments in this walkable area.
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Madonna delle Lacrime

8.8/10 (16 reviews)
You can study the exhibits at Madonna delle Lacrime, a museum with a story of its own, during your trip to Syracuse. Wander the seaside in this culturally rich area.
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Santa Lucia al Sepolcro Basilica

Find out about the history of Syracuse when you take a trip to Santa Lucia al Sepolcro Basilica. Wander the seaside in this culturally rich area.
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Papyrus Museum

8.0/10 (1 review)
You can browse the exhibits at Papyrus Museum, a museum with a storied past, during your travels to Syracuse. Wander the seaside in this culturally rich area.
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Piazza Santa Lucia

8.0/10 (1 review)
You can find out about the history of Syracuse with a trip to Piazza Santa Lucia. Wander the beautiful beaches and seaside in this culturally rich area.
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Things to do

Siracusa: Ortygia Island Boat Tour with Grotto Visit

Siracusa: Ortygia Island Boat Tour with Grotto Visit

$29
per adult
Siracusa: Ortygia Island Boat Tour with Grotto Visit
Syracuse: Ortigia Island and Sea Caves Boat Tour

Syracuse: Ortigia Island and Sea Caves Boat Tour

$23
per adult
Syracuse: Ortigia Island and Sea Caves Boat Tour
Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat

Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat

$46
per adult
Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat
See all activities in Syracuse
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.