Santa Maria Vacations from $1,146

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Your Santa Maria Vacation

Our Santa Maria vacation packages let you customize your own adventure. Tailor your getaway to your needs and interests and make every moment count in this wonderful city. Make your trip to Santa Maria even more fulfilling by including some sightseeing. Tonnarella, Piazza della Repubblica and Spiaggia di Città are some of the big attractions worth exploring. Expedia is here to help you escape your daily routine. Tailor your vacation to Santa Maria to suit your travel style, whatever that may be.

The Latest Santa Maria vacation packages

Price found within the past 48 hours. Click for updated prices.
Grand Palladium Sicilia Resort & Spa

Grand Palladium Sicilia Resort & Spa

5 out of 5
per person
Oct 15 - Oct 22
found 1 day ago
Roundtrip flight included
New York (JFK) to Palermo (PMO)
9/10 Wonderful! (105 reviews)
It’s your typical all inclusive resort, but I think they do it much better in the Caribbean. Although I’d say that the food was better here.

Reviewed on Jul 25, 2025

Baglio Oneto dei Principi di San Lorenzo - Luxury Wine Resort

Baglio Oneto dei Principi di San Lorenzo - Luxury Wine Resort

5 out of 5
Save 100% on your flight
per person
Oct 1 - Oct 7
found 13 hours ago
Roundtrip flight included
Miami (MIA) to Palermo (PMO)
9.2/10 Wonderful! (373 reviews)
A lovely place to stay with amazing sunset’s & views. Would highly recommend for a short getaway & produced some amazing wine. If you’re looking for a quality stay with good food & wine it’s well worth the stay. Staff were very friendly & has an amazing pool area. While we were there in early July it was quite quiet & we were able to enjoy the pool with hardly anybody else there. Nice wine tasting as well!

Reviewed on Jul 14, 2025

Terreforti Luxury Village

Terreforti Luxury Village

3 out of 5
Save 100% on your flight
per person
Aug 30 - Sep 5
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Palermo (PMO)
10/10 Exceptional! (3 reviews)
The property has all what you need to be comfortable, and the people are gorgeous and very kind. I highly recommend the hotel.

Reviewed on Oct 7, 2024

HOTIDAY Room Collection - San Vito Lo Capo

HOTIDAY Room Collection - San Vito Lo Capo

4 out of 5
Save 100% on your flight
per person
Oct 20 - Oct 26
found 1 day ago
Roundtrip flight included
New York (NYC) to Palermo (PMO)
10/10 Exceptional! (1 review)
We really enjoy the stay, we will come here next summer

Reviewed on Jul 18, 2025

Villa Diana

Villa Diana

3 out of 5
per person
Oct 1 - Oct 7
found 13 hours ago
Roundtrip flight included
Miami (MIA) to Palermo (PMO)
9.8/10 Exceptional! (227 reviews)
Fantastic B&B stay. Exceptional breakfast with freshly prepared bread and cake. Great location for visiting Valley of the Temples. Wonderful Hosts.

Reviewed on Jul 19, 2025

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Discover the most popular places to visit in Santa Maria

Royal Saint Nicholas

You can learn about the history of Mazara del Vallo with a trip to Royal Saint Nicholas. Discover the area's countryside and monuments.

Royal Saint Nicholas

St. Vitus on the Sea

Learn about the local history of Mazara del Vallo when you take a trip to St. Vitus on the Sea. Discover the area's countryside and monuments.

St. Vitus on the Sea

Piazza Plebiscito

Learn about the local history of Mazara del Vallo with a stop at Piazza Plebiscito. Discover the area's theater scene and monuments.

Piazza Plebiscito

What to do in Santa Maria

Daily tour in dinghy Favignana and Levanzo

Daily tour in dinghy Favignana and Levanzo

$106
per adult
Daily tour in dinghy Favignana and Levanzo
Tasting in a cellar in Marsala and tour of the Mothia lagoon

Winery tasting in Marsala and Mothia lagoon tour

$164
per adult
Winery tasting in Marsala and Mothia lagoon tour
Marsala: Winery Tour with Wine Tasting and Local Products

Marsala: Winery Tour with Wine Tasting and Local Products

$23
per adult
100% of travellers recommend
Marsala: Winery Tour with Wine Tasting and Local Products
See all activities in Santa Maria

Santa Maria Hotel Deals

Villa Carlo Resort

Villa Carlo Resort

3 out of 5
Contrada Gurgo 21m, Via Trieste, Marsala, TP
$113 nightly
The price is $132 total per night from Aug 28 to Aug 29
$132 total
Aug 28 - Aug 29
Total includes taxes and fees
8.8/10 Excellent! (75 reviews)
A trip around Sicily
"Lovely location, fantastic room, excellent breakfast and a really friendly welcome."

Reviewed on Oct 8, 2024

Villa Carlo Resort
Almar Giardino di Costanza Resort & Spa

Almar Giardino di Costanza Resort & Spa

5 out of 5
Via Salemi 100, Km 7, Mazara del Vallo, TP
Fully refundableReserve now, pay when you stay
$373 nightly
The price is $418 total per night from Aug 28 to Aug 29
$418 total
Aug 28 - Aug 29
Total includes taxes and fees
9.2/10 Wonderful! (136 reviews)
"We like the experience and the property"

Reviewed on Jul 28, 2025

Almar Giardino di Costanza Resort & Spa
Mangia's Selinunte Resort

Mangia's Selinunte Resort

4 out of 5
Contrada Belice di Mare 3, Castelvetrano, TP
$258 nightly
The price is $286 total per night from Aug 3 to Aug 4
$286 total
Aug 3 - Aug 4
Total includes taxes and fees
8/10 Very Good! (30 reviews)
stopover for a night near the beach
"enjoyable one night visit. Nice facilities."

Reviewed on Sep 5, 2023

Mangia's Selinunte Resort
See all 1,144 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Maria Vacation Packages

Santa Maria Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Vicenzo Florio Airport (TPS)
Top Sights
Tonnarella, Spiaggia di Città and Garibaldi Theater

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Frequently asked questions

How much does a Santa Maria vacation package cost?
You'll find cheap prices from $1,146 on Expedia for your Santa Maria getaway. However, factors like the season, length of stay and your choice of hotel will influence how much your vacation to Santa Maria costs.
What are the cheapest months to go to Santa Maria?
If you're looking to score a cheap Santa Maria vacation package, consider planning a trip in June, October and December. You'll generally find better rates on flights and accommodations during these quieter months — perfect for travelers wishing to save money.
How many days is enough for Santa Maria?
The ideal length for your Santa Maria vacation depends on what you'd like to see and do. Typically, a handful of days to a week will give you enough time to go to all the major sights and discover some hidden spots along the way.
How to find the best Santa Maria package deals?
Start your search for a Santa Maria package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Guest rating," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the perfect Santa Maria package deal straight away, simply change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santa Maria escape off to a flying start.
Is it cheaper to book a Santa Maria vacation as a package?
You can enjoy significant savings on your Santa Maria escape by booking a tailored vacation package. Click on the "Package" heading, then enter your travel dates and destination to browse the best hotel prices and airfares. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Santa Maria?
Secure amazing discounts by booking your flights in advance with Expedia. If spontaneity is more your thing, grab one of our last-minute deals for an impromptu Santa Maria getaway.
Does Expedia offer Book Now, Pay Later Santa Maria vacation packages?
Set off on your perfect trip to Santa Maria with help from our Book Now, Pay Later vacations. No need to save like crazy or wait for your next paycheck — we've partnered with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stick to your budget and snap up cheap deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.