Santa Maria Vacations from $880

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Your Santa Maria Vacation

Our Santa Maria vacation packages let you customize your own adventure. Tailor your getaway to your needs and interests and make every moment count in this wonderful city. Make your trip to Santa Maria even more fulfilling by including some sightseeing. Tonnarella, Piazza della Repubblica and Spiaggia di Città are some of the big attractions worth exploring. Expedia is here to help you escape your daily routine. Tailor your vacation to Santa Maria to suit your travel style, whatever that may be.

The Latest Santa Maria vacation packages

Price found within the past 48 hours. Click for updated prices.
Eurostars Centrale Palace

Eurostars Centrale Palace

4 out of 5
Palermo Historical Center
Price was $1,129, price is now $880 per person
$880
per person
Feb 12 - Feb 18
found 5 hours ago
Roundtrip flight included
New York (JFK) to Palermo (PMO)
16.8/10 Exceptional! (1,001 reviews)
very courteous and friendly staff.

Reviewed on Nov 15, 2025

Porta di Castro Hotel & Pool

Porta di Castro Hotel & Pool

1 out of 5
Palermo Historical Center
Price was $1,268, price is now $1,007 per person
$1,007
per person
Feb 12 - Feb 18
found 5 hours ago
Roundtrip flight included
New York (JFK) to Palermo (PMO)
18.8/10 Exceptional! (401 reviews)
Staff was helpful, generous and friendly. Accommodated early and late checkout. Took time to serve us a sweet and orient us with a map/list of restaurants. Breakfast was served at table with platters of pastry, meat, cheeses, fresh fruit, eggs, yogurt-very good!! The room was a little run down (we had Junior suite)-but for that it would have been excellent!!

Reviewed on Nov 13, 2025

Hotel Plaza Opera

Hotel Plaza Opera

4 out of 5
Politeama
Price was $1,105, price is now $883 per person
$883
per person
Feb 12 - Feb 18
found 5 hours ago
Roundtrip flight included
New York (JFK) to Palermo (PMO)
17.2/10 Exceptional! (590 reviews)
The only problem was that the jacuzzi was booked the entire weekend and we were not able to use it which sucks. After that was the main reason to book the hotel. None of the spa services were available because over booked. They should alert when you make the reservation.

Reviewed on Nov 15, 2025

B&B Essenze

B&B Essenze

3 out of 5
Politeama
Price was $1,124, price is now $919 per person
$919
per person
Feb 7 - Feb 13
found 1 day ago
Roundtrip flight included
Philadelphia (PHL) to Palermo (PMO)
16.4/10 Exceptional! (20 reviews)
Tutto perfetto, ospiti gentilissimi che ti fanno sentire a casa. Torneremo!

Reviewed on Sep 8, 2024

Hotel Principe di Villafranca

Hotel Principe di Villafranca

4 out of 5
Politeama
Price was $1,208, price is now $1,008 per person
$1,008
per person
Feb 12 - Feb 18
found 5 hours ago
Roundtrip flight included
New York (JFK) to Palermo (PMO)
16.8/10 Exceptional! (345 reviews)
The overall review is good. But VIP treatment was to provide.

Reviewed on Oct 20, 2025

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Discover the most popular places to visit in Santa Maria

St. Vitus on the Sea

Learn about the local history of Mazara del Vallo when you take a trip to St. Vitus on the Sea. Discover the area's countryside and monuments.

St. Vitus on the Sea

Royal Saint Nicholas

You can learn about the history of Mazara del Vallo with a trip to Royal Saint Nicholas. Discover the area's countryside and monuments.

Royal Saint Nicholas

Museum Satiro

You can spend time studying the exhibits at Museum Satiro in Mazara del Vallo. Make time to visit the monuments and churches while you're in the area.

Museum Satiro

What to do in Santa Maria

Discovering Marsala in the historic Pellegrino Cellars

Discovering Marsala in the historic Pellegrino Cellars

$23
per adult
Discovering Marsala in the historic Pellegrino Cellars
Marsala: Winery Tour with Wine Tasting and Local Products

Marsala: Winery Tour with Wine Tasting and Local Products

$23
per adult
100% of travellers recommend
Marsala: Winery Tour with Wine Tasting and Local Products
Tasting in the historic cellar of Marsala

Tasting in the historic cellar of Marsala

$24
per adult
100% of travellers recommend
Tasting in the historic cellar of Marsala
See all activities in Santa Maria

Santa Maria Hotel Deals

Grand Hotel Palace

Grand Hotel Palace

5 out of 5
Via Lungomare Mediterraneo, 57 Marsala TP
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $108 total per night from Nov 23 to Nov 24
$108 total
Nov 23 - Nov 24
Total with taxes and fees
8/10 Very Good! (284 reviews)
Hotel was a bit "tired" but a good value for the price

Reviewed on Oct 16, 2025

Grand Hotel Palace
Baglio Oneto dei Principi di San Lorenzo - Luxury Wine Resort

Baglio Oneto dei Principi di San Lorenzo - Luxury Wine Resort

5 out of 5
Contrada Baronazzo Amafi, 8 Marsala TP
9.2/10 Wonderful! (381 reviews)
.

Reviewed on Nov 6, 2025

Get rates
Baglio Oneto dei Principi di San Lorenzo - Luxury Wine Resort
Hotel D'Angelo Palace

Hotel D'Angelo Palace

3 out of 5
Via Michelangelo Buonarroti 43 Mazara del Vallo TP
Fully refundableReserve now, pay when you stay
$54 nightly
The price is $60 total per night from Nov 23 to Nov 24
$60 total
Nov 23 - Nov 24
Total with taxes and fees
7.8/10 Good! (121 reviews)
The staff went out of their way to make us feel welcome

Reviewed on Mar 5, 2025

Hotel D'Angelo Palace
See all 1,190 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Maria Vacation Packages

Santa Maria Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Vicenzo Florio Airport (TPS)
Top Sights
Tonnarella, Spiaggia di Città and Garibaldi Theater

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Frequently asked questions

How much does a Santa Maria vacation package cost?
You'll find cheap prices from $880 on Expedia for your Santa Maria getaway. However, factors like the season, length of stay and your choice of hotel will influence how much your vacation to Santa Maria costs.
What are the cheapest months to go to Santa Maria?
If you're looking to score a cheap Santa Maria vacation package, consider planning a trip in June, October and December. You'll generally find better rates on flights and accommodations during these quieter months — perfect for travelers wishing to save money.
How many days is enough for Santa Maria?
The ideal length for your Santa Maria vacation depends on what you'd like to see and do. Typically, a handful of days to a week will give you enough time to go to all the major sights and discover some hidden spots along the way.
How to find the best Santa Maria package deals?
Start your search for a Santa Maria package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Guest rating," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the perfect Santa Maria package deal straight away, simply change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santa Maria escape off to a flying start.
Is it cheaper to book a Santa Maria vacation as a package?
You can enjoy significant savings on your Santa Maria escape by booking a tailored vacation package. Click on the "Package" heading, then enter your travel dates and destination to browse the best hotel prices and airfares. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Santa Maria?
Secure amazing discounts by booking your flights in advance with Expedia. If spontaneity is more your thing, grab one of our last-minute deals for an impromptu Santa Maria getaway.
Does Expedia offer Book Now, Pay Later Santa Maria vacation packages?
Set off on your perfect trip to Santa Maria with help from our Book Now, Pay Later vacations. No need to save like crazy or wait for your next paycheck — we've partnered with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stick to your budget and snap up cheap deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.