
Santa Maria Vacations from $955
Book a Hotel + Flight or Car together to unlock savings
Your Santa Maria Vacation
Our Santa Maria vacation packages let you customize your own adventure. Tailor your getaway to your needs and interests and make every moment count in this wonderful city. Make your trip to Santa Maria even more fulfilling by including some sightseeing. Tonnarella, Piazza della Repubblica and Spiaggia di Città are some of the big attractions worth exploring. Expedia is here to help you escape your daily routine. Tailor your vacation to Santa Maria to suit your travel style, whatever that may be.
The Latest Santa Maria vacation packages
Price found within the past 48 hours. Click for updated prices.




Palazzo Sant'Agostino
Palermo Historical Center
Price was $1,216, price is now $1,130 per person
$1,130
per person
Jan 17 - Jan 22
found 19 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Palermo (PMO)
9.6/10 Exceptional! (298 reviews)
In addition to the very convenient location, the room is very clean. The breakfast is excellent. Staff are very warm and give very useful recommendations.
Reviewed on Oct 30, 2026

Bellaroto Suite & Spa - Charming Boutique Rooms
Palermo Historical Center
Price was $1,361, price is now $1,094 per person
$1,094
per person
Dec 16 - Dec 21
found 1 day ago
Roundtrip flight included
Boston (BOS) to Palermo (PMO)
9.6/10 Exceptional! (119 reviews)
Great welcome when we arrived. The room was beautiful with a little balcony.
Location was perfect.
Reviewed on Oct 30, 2026
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View all tripsWhat to do in Santa Maria

Marsala: Winery Tour with Wine Tasting and Local Products
$26
per adult
100% of travellers recommend

Discovering Marsala in the historic Pellegrino Cellars
$25
per adult

Tasting in the historic cellar of Marsala
$25
per adult
100% of travellers recommend
Santa Maria Hotel Deals

Villa Samantha, Luxury Villa less than 1km from the beach
Mazara del Vallo TP Sicily

SEAWATER HOTEL BIO & BEAUTY SPA
Via Trapani 330 Marsala TP
$55 nightly
The price is $60 total per night from Nov 21 to Nov 22
$60 total
Nov 21 - Nov 22
Total with taxes and fees

Mangia's Selinunte Resort
Contrada Belice di Mare 3 Castelvetrano TP
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa Maria Vacation Packages
Santa Maria Essential Information
Language | Italian |
|---|---|
Currency | Euros |
Local Welcome | Ciao |
Local Goodbye | Ciao |
Closest Airport | Vicenzo Florio Airport (TPS) |
Top Sights | Tonnarella, Spiaggia di Città and Garibaldi Theater |
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Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.


















