Santa Maria Vacations from $908

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Your Santa Maria Vacation

Our Santa Maria vacation packages let you customize your own adventure. Tailor your getaway to your needs and interests and make every moment count in this wonderful city. Make your trip to Santa Maria even more fulfilling by including some sightseeing. Tonnarella, Piazza della Repubblica and Spiaggia di Città are some of the big attractions worth exploring. Expedia is here to help you escape your daily routine. Tailor your vacation to Santa Maria to suit your travel style, whatever that may be.

The Latest Santa Maria vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Plaza Opera

Hotel Plaza Opera

4 out of 5
Politeama
Price was $1,117, price is now $908 per person
$908
per person
Mar 23 - Mar 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Palermo (PMO)
8.6/10 Excellent! (590 reviews)
Excellent room, clean well taken care of. Excellent staff.

Reviewed on Dec 28, 2025

Boutique B&B Vintage

Boutique B&B Vintage

3 out of 5
Palermo Historical Center
Price was $2,155, price is now $1,103 per person
$1,103
per person
Mar 9 - Mar 15
found 11 hours ago
Roundtrip flight included
Detroit (DTW) to Palermo (PMO)
9.6/10 Exceptional! (495 reviews)
The room was comfortable and clean. Breakfast was tasty with great coffee. My only issue was the stairs up to the room. It would have been helpful if there was a luggage lift.

Reviewed on Oct 29, 2025

Hotiday Mondello Beach

Hotiday Mondello Beach

4 out of 5
Partanna - Mondello
Save 100% on your flight
Price was $3,574, price is now $2,470 per person
$2,470
per person
Mar 4 - Mar 9
found 8 hours ago
Roundtrip non-stop flight included
New York (JFK) to Palermo (PMO)
9/10 Wonderful! (7 reviews)
The Hotiday Room Collection in Mondello was very modern and clean. The staff were super friendly and the breakfast was amazing!

Reviewed on Sep 28, 2025

Tenute Baglio Passofondo

Tenute Baglio Passofondo

5 out of 5
Price was $1,347, price is now $962 per person
$962
per person
Mar 23 - Mar 27
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Palermo (PMO)
9.2/10 Wonderful! (9 reviews)
Beautiful boutique property with views of the rolling hills! We were traveling with two children and the suite was comfortable for us all. Smaller pool but perfect for cooling off. Breakfast was lovely!

Reviewed on Aug 12, 2025

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Discover the most popular places to visit in Santa Maria

Royal Saint Nicholas

You can learn about the history of Mazara del Vallo with a trip to Royal Saint Nicholas. Discover the area's countryside and monuments.

Royal Saint Nicholas

Museum Satiro

You can spend time studying the exhibits at Museum Satiro in Mazara del Vallo. Make time to visit the monuments and churches while you're in the area.

Museum Satiro

St. Vitus on the Sea

Learn about the local history of Mazara del Vallo when you take a trip to St. Vitus on the Sea. Discover the area's countryside and monuments.

St. Vitus on the Sea

What to do in Santa Maria

Discovering Marsala in the historic Pellegrino Cellars

Discovering Marsala in the historic Pellegrino Cellars

$24
per adult
Discovering Marsala in the historic Pellegrino Cellars
Marsala: Winery Tour with Wine Tasting and Local Products

Marsala: Winery Tour with Wine Tasting and Local Products

$24
per adult
100% of travellers recommend
Marsala: Winery Tour with Wine Tasting and Local Products
DonnaGiacoma Experience

DonnaGiacoma Experience

$21
per adult
DonnaGiacoma Experience
See all activities in Santa Maria

Santa Maria Hotel Deals

Baglio Sciacca for groups with private pool by Xenia Sicily Villas

Baglio Sciacca for groups with private pool by Xenia Sicily Villas

MAZARA DEL VALLO Sicily
Really nice villa, Francesco was an excellent host who gave us lots of good information
Our group of 14 had a great time, the pool was very good and clean. All in all a really nice place

Reviewed on Jun 3, 2018

Get rates
Baglio Sciacca for groups with private pool by Xenia Sicily Villas
Hotel Carmine

Hotel Carmine

Piazza Carmine 16 Marsala TP
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $85 total per night from Jan 26 to Jan 27
$85 total
Jan 26 - Jan 27
Total with taxes and fees
9.4/10 Exceptional! (231 reviews)
One of the nicest hotels I have ever stayed in. The staff was lovely and the property was gorgeous.

Reviewed on Dec 14, 2025

Hotel Carmine
Grand Hotel Palace

Grand Hotel Palace

5 out of 5
Via Lungomare Mediterraneo, 57 Marsala TP
Fully refundableReserve now, pay when you stay
$142 nightly
The price is $157 total per night from Jan 22 to Jan 23
$157 total
Jan 22 - Jan 23
Total with taxes and fees
8/10 Very Good! (287 reviews)
Hotel was a bit "tired" but a good value for the price

Reviewed on Oct 16, 2025

Grand Hotel Palace
See all 1,161 properties in Santa Maria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Maria Vacation Packages

Santa Maria Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Closest Airport
Vicenzo Florio Airport (TPS)
Top Sights
Tonnarella, Spiaggia di Città and Garibaldi Theater

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Frequently asked questions

How much does a Santa Maria vacation package cost?
You'll find cheap prices from $908 on Expedia for your Santa Maria getaway. However, factors like the season, length of stay and your choice of hotel will influence how much your vacation to Santa Maria costs.
What are the cheapest months to go to Santa Maria?
If you're looking to score a cheap Santa Maria vacation package, consider planning a trip in June, October and December. You'll generally find better rates on flights and accommodations during these quieter months — perfect for travelers wishing to save money.
How many days is enough for Santa Maria?
The ideal length for your Santa Maria vacation depends on what you'd like to see and do. Typically, a handful of days to a week will give you enough time to go to all the major sights and discover some hidden spots along the way.
How to find the best Santa Maria package deals?
Start your search for a Santa Maria package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select a few filters, like "Property type" and "Guest rating," to fine-tune the results to your exact style. You can also sort by "Package discount" and browse offers that come with irresistible savings. If you don't find the perfect Santa Maria package deal straight away, simply change your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santa Maria escape off to a flying start.
Is it cheaper to book a Santa Maria vacation as a package?
You can enjoy significant savings on your Santa Maria escape by booking a tailored vacation package. Click on the "Package" heading, then enter your travel dates and destination to browse the best hotel prices and airfares. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Santa Maria?
Secure amazing discounts by booking your flights in advance with Expedia. If spontaneity is more your thing, grab one of our last-minute deals for an impromptu Santa Maria getaway.
Does Expedia offer Book Now, Pay Later Santa Maria vacation packages?
Set off on your perfect trip to Santa Maria with help from our Book Now, Pay Later vacations. No need to save like crazy or wait for your next paycheck — we've partnered with online lender Affirm to give you more financial flexibility. Our vacation packages with payment plans allow you to spread the cost over 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stick to your budget and snap up cheap deals while they last.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.