Santa Maria Vacation Rentals

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Check prices for these dates

In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

Our top choices for Santa Maria vacation rentals

A building with a staircase and a white awning.

1. SUD12 - Case vacanze

SUD12 - Case vacanze
Mazara del Vallo
8.8 out of 10, Excellent, (21 reviews)
"Place is equipped with most of what you gonna need ... eurospin and groceries are around..beach is nearby "
United Kingdom
MOAMEN
$33 nightly
The price is $36
Nov 16 - Nov 17
Total with taxes and fees
SUD12 - Case vacanze
A spacious living area with a sofa, armchairs, and a coffee table. There are two large potted plants and a painting on the wall.

2. Greta Rooms Hotel

Greta Rooms Hotel
3.0 star property
Mazara del Vallo
8.0 out of 10, Very good, (34 reviews)
"Staff were very nice, good location "
Canada
Frederick
$39 nightly
The price is $43
Nov 14 - Nov 15
Total with taxes and fees
Greta Rooms Hotel
A modern hotel room with a walk-in closet, a compact kitchenette, and a view of the hallway.

3. Serena Palace Superior Rooms

Serena Palace Superior Rooms
Mazara del Vallo
9.6 out of 10, Exceptional, (12 reviews)
"Beautiful and comfortable staying at Serena Palace! Room and bathroom with all amenities, soundproof windows, and a very comfortable bed. Easy check-in and prompt responses from the owner. Great location right next to the old city, kasba, lots of restaurants, and interesting art!"
United States
Luisa
$37 nightly
The price is $41
Nov 11 - Nov 12
Total with taxes and fees
Serena Palace Superior Rooms
A dining area with a table set for breakfast, including fruits, pastries, and beverages.

4. Volturno3 Suites & more

Volturno3 Suites & more
Mazara del Vallo
9.8 out of 10, Exceptional, (13 reviews)
"Nice Place with a very nice owner"
Germany
Johannes
$67 nightly
The price is $73
Dec 7 - Dec 8
Total with taxes and fees
Volturno3 Suites & more
A hotel room with a bed, a bench with a bag, a table with chairs, and a view of the outside.

5. Travini Hotel Residence

Travini Hotel Residence
4.0 star property
Marsala
9.0 out of 10, Wonderful, (52 reviews)
"Great parking and breakfast "
Australia
Louise
$77 nightly
The price is $92
Nov 8 - Nov 9
Total with taxes and fees
Travini Hotel Residence
A breakfast setup on a glass table with wicker chairs, featuring a coffee pot, cups, a jug, and orange juice.

6. B&B Il Tempio di Hera

B&B Il Tempio di Hera
Castelvetrano
9.6 out of 10, Exceptional, (120 reviews)
"We enjoyed our stay here. Our host was very helpful and the location was excellent for visiting the Temples and also walking to the beaches and restaurants. Breakfast was very nice as well and the free and safe onsite parking was appreciated. "
United Kingdom
Gary
$76 nightly
The price is $84
Nov 27 - Nov 28
Total with taxes and fees
B&B Il Tempio di Hera
A poolside area with lounge chairs, a swimming pool, and a sunset sky.

7. Signorino Resort & Spa

Signorino Resort & Spa
Marsala
9.4 out of 10, Exceptional, (66 reviews)
"Wonderful staff and a beautiful location. Will stay here again in the future."
United States
Christopher
$61 nightly
The price is $71
Nov 9 - Nov 10
Total with taxes and fees
Signorino Resort & Spa
A covered outdoor seating area with wicker furniture, a table, and chairs.

8. Holiday Home 'Da Mariano Apartment 2' with Shared Garden, Wi-Fi and Air Conditioning

Holiday Home 'Da Mariano Apartment 2' with Shared Garden, Wi-Fi and Air Conditioning
Mazara del Vallo
$98 nightly
The price is $101
Nov 14 - Nov 15
Total with taxes and fees
Holiday Home 'Da Mariano Apartment 2' with Shared Garden, Wi-Fi and Air Conditioning
A covered outdoor seating area with a table and chairs, a door, and a view of the city.

9. Holiday Home 'Da Mariano Apartment' with Shared Garden, Wi-Fi and Air Conditioning

Holiday Home 'Da Mariano Apartment' with Shared Garden, Wi-Fi and Air Conditioning
Mazara del Vallo
$111 nightly
The price is $115
Dec 6 - Dec 7
Total with taxes and fees
Holiday Home 'Da Mariano Apartment' with Shared Garden, Wi-Fi and Air Conditioning
A gated entrance to Villa Sermoni casa vacanze with a clear sky above.

10. Vacation Home with Pool and Grill in Mazara del Vallo

Vacation Home with Pool and Grill in Mazara del Vallo
Mazara del Vallo
$91 nightly
The price is $94
Nov 8 - Nov 9
Total with taxes and fees
Vacation Home with Pool and Grill in Mazara del Vallo
A modern hotel room with a large bed, a bedside table with a lamp, and a view of the adjacent room.

11. SHoruq

SHoruq
3.0 star property
Marsala
9.8 out of 10, Exceptional, (19 reviews)
"Great hotel, very new and clean."
United States
Jens
$94 nightly
The price is $103
Nov 17 - Nov 18
Total with taxes and fees
SHoruq
A swimming pool surrounded by palm trees and rocks, with a white wall and a building in the background.

12. TORTUGA3 APARTMENT WITH SHARED POOL USABLE AT NIGHT

TORTUGA3 APARTMENT WITH SHARED POOL USABLE AT NIGHT
Mazara del Vallo
$191 nightly
The price is $194
Nov 14 - Nov 15
Total with taxes and fees
TORTUGA3 APARTMENT WITH SHARED POOL USABLE AT NIGHT
A balcony with a view of the sea, potted plants, and a railing.

13. Sunset Terrace Mazara - One bedroom flat with stunning sea view rooftop

Sunset Terrace Mazara - One bedroom flat with stunning sea view rooftop
Mazara del Vallo
$188 nightly
The price is $192
Dec 1 - Dec 2
Total with taxes and fees
Sunset Terrace Mazara - One bedroom flat with stunning sea view rooftop
A swimming pool with lounge chairs and umbrellas.

14. Lilybeo Village - Camping & Residence

Lilybeo Village - Camping & Residence
Marsala
8.8 out of 10, Excellent, (18 reviews)
"Lo consiglio "
Italy
carlo
$69 nightly
The price is $78
Nov 14 - Nov 15
Total with taxes and fees
Lilybeo Village - Camping & Residence
A swimming pool with a curved design, surrounded by a tiled patio and potted plants.

15. "FORTUNA" Luxurious double room in a prestigious villa with a shared pool.

"FORTUNA" Luxurious double room in a prestigious villa with a shared pool.
Mazara del Vallo
10.0 out of 10, Exceptional, (1 review)
"Accueil du propriétaire chaleureux même s'il était très tard dans la nuit. Petit cadeau gastronomique lors du séjour très apprécié. Maison magnifique très très bien entretenue avec une bellepiscine accessible à tout moment. Très bien conseillé par notre propriétaire Roberto qui parle très bien anglais. Bref un endroit agréable où se poser pour des vacances dans la partie ouest de la Sicile"
France
sebastien p.
$191 nightly
The price is $194
Nov 14 - Nov 15
Total with taxes and fees
"FORTUNA" Luxurious double room in a prestigious villa with a shared pool.
A hot tub in a covered outdoor area with a stone wall and wooden beams.

16. Appartamento con Angolo Cottura a due Passi Dalla Spiaggia con Jacuzzi e bbq

Appartamento con Angolo Cottura a due Passi Dalla Spiaggia con Jacuzzi e bbq
Mazara del Vallo
$154 nightly
The price is $157
Nov 9 - Nov 10
Total with taxes and fees
Appartamento con Angolo Cottura a due Passi Dalla Spiaggia con Jacuzzi e bbq
A silver sedan parked in a driveway with a swimming pool in the background.

17. DOUBLE ROOM WITH KITCHEN AND PRIVATE SPACE IN LUXURY VILLA WITH POOL

DOUBLE ROOM WITH KITCHEN AND PRIVATE SPACE IN LUXURY VILLA WITH POOL
MAZARA DEL VALLO
$191 nightly
The price is $194
Nov 14 - Nov 15
Total with taxes and fees
DOUBLE ROOM WITH KITCHEN AND PRIVATE SPACE IN LUXURY VILLA WITH POOL
A balcony with two wooden chairs and a small table, overlooking a river with boats and buildings in the background.

18. Apartment 'Tramonto Mediterraneo' with Sea View, Wi-Fi and Air Conditioning

Apartment 'Tramonto Mediterraneo' with Sea View, Wi-Fi and Air Conditioning
Mazara del Vallo Historic Center
8.0 out of 10, Very good, (1 review)
"Pros: Der Gastgeber war sehr freundlich und zuvorkommend. Die Lage war ebenfalls top. Cons: Leider war die Küche nicht so gut ausgestattet"
Germany
Anonymous traveler
$124 nightly
The price is $127
Nov 10 - Nov 11
Total with taxes and fees
Apartment 'Tramonto Mediterraneo' with Sea View, Wi-Fi and Air Conditioning
An outdoor lounge area with white umbrellas, lounge chairs, and potted plants.

19. Sunset Terrace Mazara, studio apartment with access to shared sea view rooftop

Sunset Terrace Mazara, studio apartment with access to shared sea view rooftop
Mazara del Vallo
10.0 out of 10, Exceptional, (1 review)
"Appartamento molto confortevole ed assistenza al Check in e Check Out in autonomia bnene organizzata."
Italy
Anonymous traveler
$242 nightly
The price is $242
Nov 14 - Nov 15
Total with taxes and fees
Sunset Terrace Mazara, studio apartment with access to shared sea view rooftop
A cozy interior with wicker furniture, a stone wall, and a wooden cabinet with decorative items.

20. Holiday Home 'Il Ficus' with Private Terrace, Wi-Fi and Air Conditioning

Holiday Home 'Il Ficus' with Private Terrace, Wi-Fi and Air Conditioning
Mazara Del Vallo
10.0 out of 10, Exceptional, (3 reviews)
"Mazara is an undiscovered gem. Il Ficus is a 5 star property that reflects Mazara’s rich Moorish history"
Canada
Palma L.
$170 nightly
The price is $174
Nov 9 - Nov 10
Total with taxes and fees
Holiday Home 'Il Ficus' with Private Terrace, Wi-Fi and Air Conditioning
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Maria Hotel Reviews

A dining area with a table set for breakfast, including fruits, pastries, and beverages.
Volturno3 Suites & more

Volturno3 Suites & more

Volturno3 Suites & more
Mazara del Vallo

10/10 Excellent

Excellent stay at Volturno3. Room very spacious, well furnished and very clean. Conveniently located near the city center. The owners are very nice and always go above and beyond. I highly recommend it
United States
Francesco
Reviewed May 20, 2025
Volturno3 Suites & more

Find out more about Santa Maria

Everything you need to know about Santa Maria vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Maria vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Maria vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Maria vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Maria. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Maria in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $36 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Maria rentals

At Expedia, we put the best Santa Maria vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Maria rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Maria vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Maria. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Can I find vacation rentals in Santa Maria?

Yes, we have vacation rentals near well known sights in Santa Maria, or you can go with a secluded option if you're looking for relaxation.

What are some of the best vacation rentals that Santa Maria has to offer?

Dimora San Girolamo: This vacation home rental near Santa Maria is located in the city center and offers a terrace, daily housekeeping, and free WiFi to help you feel perfectly comfortable in your new surroundings.

What’s there to see and do in Santa Maria?

Explore the area and family-friendly sights such as ASD Reef Puzziteddu, or get out into nature at a spot like Tonnarella. In the larger area, you’ll find Piazza della Repubblica and Marco De Bartoli - Samperi.

What’s a vacation rental in Santa Maria like?

Vacation rentals are privately owned properties where you can stay for a long or short time in Santa Maria. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, a vacation rental can provide a sense of security away from public hotel elevators and lobbies packed with people while still allowing you the experience of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular option for a small group gathering.