Santa María Vacations from $197

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Your Santa María Vacation

With plenty of highlights as well as some hidden gems, this city is best explored with a Santa María vacation package. Find a place to stay in El Arenal, which is good for walking, watersports and coastal beaches. If some sightseeing is on the agenda during your trip to Santa María, swing by leading attractions such as General Villamil Beach. No matter your travel plans or budget, putting together the ultimate tailored Santa María vacation is a cinch with Expedia.

The Latest Santa María vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Chat Noir Cuenca

Hotel Chat Noir Cuenca

3 out of 5
Downtown Cuenca
Price was $276, price is now $197 per person
$197
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
7.8/10 Good! (11 reviews)

Hotel El Conquistador

Hotel El Conquistador

4 out of 5
Downtown Cuenca
Price was $394, price is now $214 per person
$214
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
7.8/10 Good! (148 reviews)
Toallas viejas y manchadas

Reviewed on Sep 18, 2026

Hotel Río Guayas by Art Hotels Ecuador

Hotel Río Guayas by Art Hotels Ecuador

4 out of 5
Las Peñas
Price was $2,431, price is now $1,481 per person
$1,481
per person
Dec 6 - Dec 11
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE)
10/10 Exceptional! (5 reviews)

Hotel Cruz del Vado by Art Hotels Ecuador

Hotel Cruz del Vado by Art Hotels Ecuador

4.5 out of 5
Price was $525, price is now $385 per person
$385
per person
Dec 24 - Dec 27
found 1 day ago
Roundtrip flight included
Quito (UIO) to Guayaquil (GYE)
9.4/10 Exceptional! (46 reviews)
Our room was unbearably hot. Imposible to sleep. Front desk’s response was that the city was unusually warm. Restaurant was very uneven, could be rated a 1 or a 5 depending on the day or meal.

Reviewed on Oct 24, 2026

Hospedaje Casa Aida Victoria

Hospedaje Casa Aida Victoria

1 out of 5
Downtown Cuenca
Price was $44,766, price is now $32,954 per person
$32,954
per person
Jan 22 - Jan 29
found 1 day ago
Roundtrip non-stop flight included
New York (JFK) to Guayaquil (GYE)
No reviews

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What to do in Santa María

Navigate through the mangroves and discover the magic of bottlenose dolphins in their natural habitat, just a short distance from Guayaquil

Full Day Dolphins Mangroves and Birdwatching Tour from Guayaquil

$231
per adult
Full Day Dolphins Mangroves and Birdwatching Tour from Guayaquil
See all activities in Santa María

Santa María Hotel Deals

Hotel La Ría Playas

Hotel La Ría Playas

3 out of 5
Km 1.5 Vía a Data Playas Guayas
$63 nightly
The price is $63 total per night from Nov 5 to Nov 6
$63 total
Nov 5 - Nov 6
Hotel La Ría Playas
Hotel Presidente Beach Playas

Hotel Presidente Beach Playas

3 out of 5
C. 1 Playas Guayas
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $94 total per night from Nov 29 to Nov 30
$94 total
Nov 29 - Nov 30
8.8/10 Excellent! (47 reviews)
"El personal es excelente. Todos, desde la recepcionista hasta la persona que retira la vajilla son muy amables y amistosos. El cuarto estuvo muy limpio y ordenado. La comida estuvo buena y la caída del sol espectacular."

Reviewed on Oct 19, 2026

Hotel Presidente Beach Playas
Karibao Resort Town

Karibao Resort Town

4 out of 5
Km 7.5 Via a Playas Engabao Playas Guayas
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $110 total per night from Dec 5 to Dec 6
$110 total
Dec 5 - Dec 6
Karibao Resort Town
See all 62 properties in Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa María Vacation Packages

Santa Marían Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

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Frequently asked questions

How much does a Santa María vacation package cost?
You'll find cheap prices from $197 on Expedia for your Santa Marían escape. However, a range of factors like the length of stay, hotel choice and season will determine how much your vacation to Santa María costs.
What are the cheapest months to go to Santa María?
If you're hoping to score a cheap Santa María vacation package, consider traveling in December, January and February. You'll typically find better prices on hotels and airfares during these months — ideal for a budget-friendly getaway.
How many days is enough for Santa María?
With a well-organized travel plan, you can easily tick off the main Santa Marían attractions in a few days. But if you want to explore off the beaten track or go on day tours, think about booking your Santa María vacation for longer.
How to find the best Santa María package deals?
Use Expedia's filter tool to help you find some unbeatable Santa María package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your trip for midweek, or look for Santa María package deals in the off-season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as early as possible.
Is it cheaper to book a Santa María vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking hotels and flights individually. Better still, you can customize your Santa Marían escape to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Santa María?
If you've got your Santa María vacation dates finalized, book as soon as you can to snap up some awesome deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are perfect for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Santa María vacation packages?
Your Santa María getaway should be an escape from your daily routine, not a reason for money-related stress. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.