Santa María Vacations from $795
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Your Santa María Vacation
With plenty of highlights as well as some hidden gems, this city is best explored with a Santa María vacation package. Find a place to stay in El Arenal, which is good for walking, watersports and coastal beaches. If some sightseeing is on the agenda during your trip to Santa María, swing by leading attractions such as General Villamil Beach. No matter your travel plans or budget, putting together the ultimate tailored Santa María vacation is a cinch with Expedia.
The Latest Santa María vacation packages
Price found within the past 48 hours. Click for updated prices.
Luxury Suites Riverfront GYE
Puerto Santa Ana
$795
per person
Sep 21 - Sep 28
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE)
9.4/10 Exceptional! (107 reviews)
So clean and very nice people. I really recommend this facility, nice environment. My next trip lm booking in this apartment
Reviewed on Aug 10, 2026
Hotel Río Guayas by Art Hotels Ecuador
Tarqui
$2,072
per person
Sep 21 - Sep 28
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE)
10/10 Exceptional! (3 reviews)
The staff was very friendly and helpful. The hotel is new and modern, it is a good place to relax and work.
Reviewed on Oct 25, 2025
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View all tripsWhat to do in Santa María
Full Day Dolphins Mangroves and Birdwatching Tour from Guayaquil
$231
per adult
Santa María Hotel Deals
Hotel Presidente Beach Playas
C. 1 Playas Guayas
Fully refundableReserve now, pay when you stay
$89 nightly
$89 total
Aug 30 - Aug 31
8.8/10 Excellent! (44 reviews)
"Staff is pretty good 👍"
Reviewed on Jun 28, 2026
Hotel La Ría Playas
Km 1.5 Vía a Data Playas Guayas
$60 nightly
$60 total
Aug 12 - Aug 13
7.8/10 Good! (59 reviews)
"Gracias"
Reviewed on Aug 9, 2026
Karibao Resort Town
Km 7.5 Via a Playas Engabao Playas Guayas
Fully refundableReserve now, pay when you stay
$104 nightly
$114 total
Aug 12 - Aug 13
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Santa María Vacation Packages
Santa Marían Essential Information
Language | Spanish |
|---|---|
Currency | U.S dollars |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
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Frequently asked questions
How much does a Santa María vacation package cost?
You'll find cheap prices from $795 on Expedia for your Santa Marían escape. However, a range of factors like the length of stay, hotel choice and season will determine how much your vacation to Santa María costs.
What are the cheapest months to go to Santa María?
If you're hoping to score a cheap Santa María vacation package, consider traveling in December, January and February. You'll typically find better prices on hotels and airfares during these months — ideal for a budget-friendly getaway.
How many days is enough for Santa María?
With a well-organized travel plan, you can easily tick off the main Santa Marían attractions in a few days. But if you want to explore off the beaten track or go on day tours, think about booking your Santa María vacation for longer.
How to find the best Santa María package deals?
Use Expedia's filter tool to help you find some unbeatable Santa María package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your trip for midweek, or look for Santa María package deals in the off-season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as early as possible.
Is it cheaper to book a Santa María vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking hotels and flights individually. Better still, you can customize your Santa Marían escape to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Santa María?
If you've got your Santa María vacation dates finalized, book as soon as you can to snap up some awesome deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are perfect for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Santa María vacation packages?
Your Santa María getaway should be an escape from your daily routine, not a reason for money-related stress. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
