Santa María Vacations from $238

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Your Santa María Vacation

With plenty of highlights as well as some hidden gems, this city is best explored with a Santa María vacation package. Find a place to stay in El Arenal, which is good for walking, watersports and coastal beaches. If some sightseeing is on the agenda during your trip to Santa María, swing by leading attractions such as General Villamil Beach. No matter your travel plans or budget, putting together the ultimate tailored Santa María vacation is a cinch with Expedia.

The Latest Santa María vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Presidente Internacional

Hotel Presidente Internacional

3.5 out of 5
Downtown Guayaquil
Price was $329, price is now $238 per person
$238
per person
Apr 4 - Apr 8
found 21 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Guayaquil (GYE)
6/10 (27 reviews)
Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

3.5 out of 5
Puerto Santa Ana
Price was $425, price is now $306 per person
$306
per person
Apr 4 - Apr 8
found 21 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Guayaquil (GYE)
9.4/10 Exceptional! (99 reviews)
Everything was excellent, and very clean I give it a 10 out of 10 rating. Thank you.

Reviewed on Jan 8, 2026

Hotel del Parque

Hotel del Parque

4.5 out of 5
Save 100% on your flight
Price was $1,863, price is now $1,344 per person
$1,344
per person
Feb 12 - Feb 16
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Guayaquil (GYE)
9.8/10 Exceptional! (104 reviews)
Friendly staff. We arrived very early and they were ablemto accommodate an early check-in. The hotel is beautiful

Reviewed on Dec 16, 2025

Hotel Plaza Monte Carlo

Hotel Plaza Monte Carlo

3 out of 5
Garzota
Price was $460, price is now $352 per person
$352
per person
Apr 4 - Apr 8
found 21 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Guayaquil (GYE)
8.6/10 Excellent! (9 reviews)
Hotel Marcelius

Hotel Marcelius

3.5 out of 5
Kennedy
Price was $393, price is now $302 per person
$302
per person
Apr 4 - Apr 8
found 21 hours ago
Roundtrip flight included
Fort Lauderdale (FLL) to Guayaquil (GYE)
8.2/10 Very Good! (221 reviews)
All amenities ok good personal

Reviewed on Jan 2, 2026

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Santa María Hotel Deals

Hotel La Ría Playas

Hotel La Ría Playas

3 out of 5
Km 1.5 Vía a Data Playas Guayas
$84 nightly
The price is $84 total per night from Jan 10 to Jan 11
$84 total
Jan 10 - Jan 11
7.6/10 Good! (47 reviews)
Overall, it was an okay experience; we truly didn't even stay the full reservation. The one bad thing is that we couldn't cancel.

Reviewed on Oct 5, 2025

Hotel La Ría Playas
Hotel Presidente Beach Playas

Hotel Presidente Beach Playas

3 out of 5
C. 1 Playas Guayas
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $100 total per night from Jan 29 to Jan 30
$100 total
Jan 29 - Jan 30
8.8/10 Excellent! (33 reviews)
That's all ok

Reviewed on Oct 11, 2025

Hotel Presidente Beach Playas
Karibao Resort Town

Karibao Resort Town

4 out of 5
Km 7.5 Via a Playas Engabao Playas Guayas
Fully refundableReserve now, pay when you stay
$105 nightly
The price is $115 total per night from Jan 13 to Jan 14
$115 total
Jan 13 - Jan 14
9/10 Wonderful! (14 reviews)
Mejor atención

Reviewed on Aug 19, 2025

Karibao Resort Town
See all 54 properties in Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa María Vacation Packages

Santa Marían Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

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Frequently asked questions

How much does a Santa María vacation package cost?
You'll find cheap prices from $238 on Expedia for your Santa Marían escape. However, a range of factors like the length of stay, hotel choice and season will determine how much your vacation to Santa María costs.
What are the cheapest months to go to Santa María?
If you're hoping to score a cheap Santa María vacation package, consider traveling in December, January and February. You'll typically find better prices on hotels and airfares during these months — ideal for a budget-friendly getaway.
How many days is enough for Santa María?
With a well-organized travel plan, you can easily tick off the main Santa Marían attractions in a few days. But if you want to explore off the beaten track or go on day tours, think about booking your Santa María vacation for longer.
How to find the best Santa María package deals?
Use Expedia's filter tool to help you find some unbeatable Santa María package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your trip for midweek, or look for Santa María package deals in the off-season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as early as possible.
Is it cheaper to book a Santa María vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking hotels and flights individually. Better still, you can customize your Santa Marían escape to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Santa María?
If you've got your Santa María vacation dates finalized, book as soon as you can to snap up some awesome deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are perfect for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Santa María vacation packages?
Your Santa María getaway should be an escape from your daily routine, not a reason for money-related stress. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.