Santa María Vacations from $549

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Your Santa María Vacation

With plenty of highlights as well as some hidden gems, this city is best explored with a Santa María vacation package. Find a place to stay in El Arenal, which is good for walking, watersports and coastal beaches. If some sightseeing is on the agenda during your trip to Santa María, swing by leading attractions such as General Villamil Beach. No matter your travel plans or budget, putting together the ultimate tailored Santa María vacation is a cinch with Expedia.

The Latest Santa María vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel El Conquistador

Hotel El Conquistador

4 out of 5
Downtown Cuenca
Price was $801, price is now $549 per person
$549
per person
May 7 - May 14
found 1 day ago
Roundtrip flight included
New York (JFK) to Guayaquil (GYE)
7.8/10 Good! (134 reviews)
La atención y habitación estuvieron bien pero en especificación pone que tienen Parqueo incluido pero el Parqueo está a dos cuadras y cobran $12,50 por día adicional

Reviewed on Dec 4, 2025

Hotel Cruz del Vado by Art Hotels Ecuador

Hotel Cruz del Vado by Art Hotels Ecuador

4.5 out of 5
Save 100% on your flight
Price was $1,497, price is now $898 per person
$898
per person
May 7 - May 14
found 1 day ago
Roundtrip flight included
New York (JFK) to Guayaquil (GYE)
9.4/10 Exceptional! (41 reviews)
Excellent service. I was pregnant and the wokers were very attentive. If you want to have a beautiful experience, It’s worth staying here.

Reviewed on Sep 26, 2025

Hotel Boutique Santa Lucia

Hotel Boutique Santa Lucia

4 out of 5
Downtown Cuenca
Save 100% on your flight
Price was $1,331, price is now $801 per person
$801
per person
May 7 - May 14
found 1 day ago
Roundtrip flight included
New York (JFK) to Guayaquil (GYE)
9.2/10 Wonderful! (376 reviews)
Una experiencia fabulosa, me hospedé dos noches en el Hotel. Cristina de recepción nos ayudó en todo, el transfer desde el aeropuerto, checkin, recomendaciones de lugares a visitar, taxis seguros, hasta el checkout. las habitaciones limpias y bien abastecidas.

Reviewed on Feb 3, 2026

Sanchz Aqua Lounge Hotel by Chat Noir

Sanchz Aqua Lounge Hotel by Chat Noir

3 out of 5
San Sebastián
Save 100% on your flight
Price was $1,377, price is now $875 per person
$875
per person
May 7 - May 14
found 1 day ago
Roundtrip flight included
New York (JFK) to Guayaquil (GYE)
7.8/10 Good! (19 reviews)
Awesome people and space.

Reviewed on Sep 15, 2025

Mantahost Hotel

Mantahost Hotel

4 out of 5
Barbasquillo
Price was $1,637, price is now $1,141 per person
$1,141
per person
Apr 4 - Apr 11
found 1 day ago
Roundtrip flight included
New York (JFK) to Guayaquil (GYE)
8.6/10 Excellent! (297 reviews)
Property is under going heavy renovation work

Reviewed on Nov 28, 2025

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Santa María Hotel Deals

Hotel La Ría Playas

Hotel La Ría Playas

3 out of 5
Km 1.5 Vía a Data Playas Guayas
$81 nightly
The price is $81 total per night from Apr 3 to Apr 4
$81 total
Apr 3 - Apr 4
Hotel La Ría Playas
Hotel Presidente Beach Playas

Hotel Presidente Beach Playas

3 out of 5
C. 1 Playas Guayas
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $98 total per night from Mar 26 to Mar 27
$98 total
Mar 26 - Mar 27
8.8/10 Excellent! (35 reviews)
Very clean well kept place, great facilities, direct access to the beach in the perfect area not too crowded but not isolated either. The property felt very secure, was a great place to relax and unwind. The parking lot is secured too. Staff were attentive and friendly. 10 out of 10, would highly ...

Reviewed on Jan 26, 2026

Hotel Presidente Beach Playas
Karibao Resort Town

Karibao Resort Town

4 out of 5
Km 7.5 Via a Playas Engabao Playas Guayas
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $149 total per night from Mar 4 to Mar 5
$149 total
Mar 4 - Mar 5
9/10 Wonderful! (14 reviews)
Mejor atención

Reviewed on Aug 19, 2025

Karibao Resort Town
See all 52 properties in Santa María
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa María Vacation Packages

Santa Marían Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós

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Frequently asked questions

How much does a Santa María vacation package cost?
You'll find cheap prices from $549 on Expedia for your Santa Marían escape. However, a range of factors like the length of stay, hotel choice and season will determine how much your vacation to Santa María costs.
What are the cheapest months to go to Santa María?
If you're hoping to score a cheap Santa María vacation package, consider traveling in December, January and February. You'll typically find better prices on hotels and airfares during these months — ideal for a budget-friendly getaway.
How many days is enough for Santa María?
With a well-organized travel plan, you can easily tick off the main Santa Marían attractions in a few days. But if you want to explore off the beaten track or go on day tours, think about booking your Santa María vacation for longer.
How to find the best Santa María package deals?
Use Expedia's filter tool to help you find some unbeatable Santa María package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your trip for midweek, or look for Santa María package deals in the off-season. Play around with your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package as early as possible.
Is it cheaper to book a Santa María vacation as a package?
An Expedia vacation package could score you significant savings when compared to booking hotels and flights individually. Better still, you can customize your Santa Marían escape to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Explore our bundles to see how much you can save.
When to book a vacation package to Santa María?
If you've got your Santa María vacation dates finalized, book as soon as you can to snap up some awesome deals. With Expedia, you can often reserve some flights up to one year in advance. Prefer spontaneous trips? Our last-minute deals are perfect for jetting off on a whim.
Does Expedia offer Book Now, Pay Later Santa María vacation packages?
Your Santa María getaway should be an escape from your daily routine, not a reason for money-related stress. So to give you more flexibility, we've teamed up with online lender Affirm to offer you our Book Now, Pay Later vacations. Pick one of our vacation packages with payment plans and break down the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.