Santa Pera Vacations from $788

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Your Santa Pera Vacation

Say goodbye to the stress of planning and hello to a Santa Pera vacation package. With your travel details organized before you go, you can focus on discovering the best of this city, starting with El Cangrejo, which is great for distilleries and craft breweries, bars and pubs and cafes. Metromall Panama is among the must-see attractions to check off your to-do list during a trip to Santa Pera. That dream Santa Pera vacation is just a few clicks away. Search accommodations, flights and more on Expedia for a trip that's tailored just for you.

The Latest Santa Pera vacation packages

Price found within the past 48 hours. Click for updated prices.
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4 out of 5
Price was $1,044, price is now $788 per person
$788
per person
Sep 22 - Sep 25
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.4/10 Very Good! (1,815 reviews)
The room was very tiny, the staff so kind

Reviewed on Jul 7, 2026

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Price was $1,551, price is now $992 per person
$992
per person
Aug 7 - Aug 10
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.2/10 Wonderful! (1,001 reviews)
Love the breakfast and the rooms were amazing

Reviewed on Jul 5, 2026

Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
San Francisco
Price was $1,359, price is now $898 per person
$898
per person
Sep 18 - Sep 22
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
8.4/10 Very Good! (1,574 reviews)
Always enjoy my stay at Megapolis Hotel. Rooms are clean, prestine and comfortable. The buffet breakfast is good.

Reviewed on Jul 8, 2026

Las Clementinas

Las Clementinas

3.5 out of 5
Casco Viejo
Price was $1,508, price is now $1,087 per person
$1,087
per person
Aug 7 - Aug 12
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9.4/10 Exceptional! (194 reviews)
The door handle broke and we got locked in the room, then that night a high pitched alarm went off and I had to call multiple times for someone to turn it off. They did after an hour or more and then it came back on a few hours later. No offer of apology or compensation for lost sleep. The staff is wonderful. Friendly and did their best, but I would not recommend.

Reviewed on Jul 5, 2026

Villa Marina Hotel

Villa Marina Hotel

3.5 out of 5
Price was $1,985, price is now $1,474 per person
$1,474
per person
Aug 15 - Aug 22
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (162 reviews)
staff helpful and very friendly, rooms super clean.

Reviewed on Jun 27, 2026

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What to do in Santa Pera

Panama City: POIN Swing Experience

Panama City: POIN Swing Experience

$32
per adult
100% of travellers recommend
Panama City: POIN Swing Experience
Panama Canal:Monkey Island,Sloth Safari, Natural Pool & Hike

Panama Canal:Monkey Island,Sloth Safari, Natural Pool & Hike

$48
per adult
94% of travellers recommend
Panama Canal:Monkey Island,Sloth Safari, Natural Pool & Hike
Panama City: Poin Full Package Experience

Panama City: Poin Full Package Experience

$155
per adult
98% of travellers recommend
Panama City: Poin Full Package Experience
See all activities in Santa Pera

Santa Pera Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
$126 nightly
The price is $139 total per night from Aug 4 to Aug 5
$139 total
Aug 4 - Aug 5
Total with taxes and fees
9/10 Wonderful! (5,707 reviews)
"Excellent"

Reviewed on Jul 8, 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
$137 nightly
The price is $151 total per night from Aug 6 to Aug 7
$151 total
Aug 6 - Aug 7
Total with taxes and fees
8.6/10 Excellent! (2,618 reviews)
"Todo estuvo bien"

Reviewed on Jul 8, 2026

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz Veracruz Panama
Fully refundableReserve now, pay when you stay
$319 nightly
The price is $319 total per night from Jul 9 to Jul 10
$319 total
Jul 9 - Jul 10
Total with taxes and fees
7.6/10 Good! (1,029 reviews)
"Very clean spacious rooms with views of the beach and resort. Breakfast was excellent!!! Staff was pleasant and willing to help!"

Reviewed on Jul 7, 2026

Dreams Playa Bonita Panama - All Inclusive
See all 1,768 properties in Santa Pera
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Pera Vacation Packages

Santa Pera Essential Information

Language
Spanish
Currency
Panamanian balboas
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Tocumen Intl. Airport (PTY)

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Frequently asked questions

How much does a Santa Pera vacation package cost?
Offering excellent value package deals from $788 on Expedia, you'll be thrilled with how little a vacation to Santa Pera costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Santa Pera?
January, July and December are great times to search for cheap Santa Pera vacation packages. Traveling in quieter months means you'll typically find better prices on flights and accommodations.
How many days is enough for Santa Pera?
With a well-organized itinerary, you can easily visit the most popular Santa Pera attractions in a few days. But if you prefer to venture off the beaten track or go on day trips, consider booking your Santa Pera vacation for longer.
How to find the best Santa Pera package deals?
Start your search for a Santa Pera package deal by entering your preferred trip dates and destination under our "Packages" tab. Then select some filters, like "Property type" and "Amenities," to fine-tune the results to your exact needs. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the ideal Santa Pera package deal right away, just tweak your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your Santa Pera escape off to a flying start.
Is it cheaper to book a Santa Pera vacation as a package?
An Expedia vacation package could land you great savings when compared to booking stays and flights separately. Better still, you can personalize your Santa Pera getaway to fit your exact style. Choose your preferred flight time, select the hotel type and add a car rental. Browse our great deals to see how much you can save.
When to book a vacation package to Santa Pera?
Land amazing discounts by booking your flights early with Expedia. If spontaneity is more your thing, take advantage of our last-minute deals for an impromptu Santa Pera getaway.
Does Expedia offer Book Now, Pay Later Santa Pera vacation packages?
Set off on your perfect escape to Santa Pera with help from Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or hold off until your next payday — we've teamed up with online lender Affirm to offer you flexibility and choice. Our vacation packages with payment plans mean you can spread the total cost across 3, 6 or 12 months. With no late payment fees or extra charges, you can easily stick to your budget and snag great deals before they sell out.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.