Santana Vacations from $364

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Photo by Norberto Moctezuma Gomez

Your Santana Vacation

When a getaway to the city is calling, answer it with a vacation package to Santana. The neighborhood of Barrio Pueblo, which is good for dining, families and fishing, makes an awesome base for your adventures. Church of Porta Coeli, Universidad Interamericana and Casa Morales are just a few of the sights worth exploring during your trip to Santana. Whatever your travel plans or the size of your budget, putting together a tailored Santana vacation is easy with Expedia.

The Latest Santana vacation packages

Price found within the past 48 hours. Click for updated prices.
San Agustin Apartments
Ola Boutique Hotel
The Oliver Hotel
Hotel Puerto Valdes
Urbana Hotel
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Santana Hotel Deals

Costa Bahia Hotel & Convention Center

Costa Bahia Hotel & Convention Center

3.5 out of 5
Exit 205 Road 127 Km 8.6 Guayanilla
$134 nightly
The price is $149 total per night from Dec 16 to Dec 17
$149 total
Dec 16 - Dec 17
Total with taxes and fees
8.8/10 Excellent! (1,858 reviews)
Great amenities, comfy rooms and great service over all. Loved the experience on this hotel. Hope to come back at some point.

Reviewed on Dec 9, 2025

Costa Bahia Hotel & Convention Center
Aquarius Vacation Club at Boqueron Beach Resort

Aquarius Vacation Club at Boqueron Beach Resort

3.5 out of 5
Carretera 101 Km 18.1 Cabo Rojo
$142 nightly
The price is $151 total per night from Dec 16 to Dec 17
$151 total
Dec 16 - Dec 17
Total with taxes and fees
9.2/10 Wonderful! (2,178 reviews)
The staff was great and hotel was in a good area, I just wish the hotel was more dated. They need some upgrades to the rooms and make them a little more modern along with the pool area, otherwise I had a good stay.

Reviewed on Dec 8, 2025

Aquarius Vacation Club at Boqueron Beach Resort
Holiday Inn Mayaguez and Tropical Casino by IHG

Holiday Inn Mayaguez and Tropical Casino by IHG

3.5 out of 5
2701 Highway #2 Hostos Avenue Mayagüez
Fully refundable
$135 nightly
The price is $150 total per night from Jan 11 to Jan 12
$150 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
9.4/10 Exceptional! (1,156 reviews)
Staff

Reviewed on Dec 11, 2025

Holiday Inn Mayaguez and Tropical Casino by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santana Vacation Packages

Santana Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Rafael Hernandez Airport (BQN)

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Frequently asked questions

How much does a Santana vacation package cost?
You'll find cheap prices from $364 on Expedia for your Santana break. However, factors like the length of stay, the season and your choice of hotel will determine how much your vacation to Santana costs.
What are the cheapest months to go to Santana?
If you're looking to book a cheap Santana vacation package, consider visiting in September, October and December. You're likely to find lower rates on flights and hotels during these months — perfect for a budget-friendly break.
How many days is enough for Santana?
Usually, a handful of days is enough to see the top attractions during your Santana vacation. However, if you'd like to have more time to rest or take day tours, think about extending your trip.
How to find the best Santana package deals?
Begin your search for a Santana package deal by entering your preferred trip dates and destination under our "Packages" tab. Then apply some filters, like "Guest rating" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the ideal Santana package deal straight away, just change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santana escape underway.
Is it cheaper to book a Santana vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and you could save hundreds of dollars. You'll usually snag a better deal than booking each component individually. And you'll still enjoy the flexibility to create a personalized Santana vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Santana?
If you're planning an impromptu Santana getaway, browse our last-minute deals that can be booked up to one week before you go. Don't want to leave things to the last minute? You can find amazing deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Santana vacation packages?
If you're anything like us, you love traveling the world but are not a fan of the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Santana trip across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.