Santana Vacations from $404

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Your Santana Vacation

When a getaway to the city is calling, answer it with a vacation package to Santana. The neighborhood of Barrio Pueblo, which is good for dining, families and fishing, makes an awesome base for your adventures. Church of Porta Coeli, Universidad Interamericana and Casa Morales are just a few of the sights worth exploring during your trip to Santana. Whatever your travel plans or the size of your budget, putting together a tailored Santana vacation is easy with Expedia.

The Latest Santana vacation packages

Price found within the past 48 hours. Click for updated prices.
Fortaleza Suites
Urbana Hotel
El Colonial - Adults Only
Romeo Gay Hotel
 Ciqala Suites Hotel
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Santana Hotel Deals

Aquarius Vacation Club at Boqueron Beach Resort
Aquarius Vacation Club at Boqueron Beach Resort
3.5 out of 5
Carretera 101 Km 18.1, Acceso Balneario de Boqueron, Cabo Rojo
$156 nightly
The price is $167 total per night from Jun 29 to Jun 30
$167 total
Jun 29 - Jun 30
Total includes taxes and fees
9.2/10 Wonderful! (1,803 reviews)
Surprisingly Exceptional Service
"This hotel may be simple, but the front desk service is truly five-star. Warm, attentive, and genuinely kind, they made me feel more welcome than many luxury hotels ever have. It’s the kind of hospitality that stays with you. I’d come back just for that."

Reviewed on Jun 23, 2025

Aquarius Vacation Club at Boqueron Beach Resort
Costa Bahia Hotel & Convention Center
Costa Bahia Hotel & Convention Center
3.5 out of 5
Exit 205 Road 127 Km 8.6, Guayanilla
$140 nightly
The price is $156 total per night from Jun 29 to Jun 30
$156 total
Jun 29 - Jun 30
Total includes taxes and fees
8.8/10 Excellent! (1,625 reviews)
"Love it"

Reviewed on Jun 25, 2025

Costa Bahia Hotel & Convention Center
Holiday Inn Mayaguez and Tropical Casino by IHG
Holiday Inn Mayaguez and Tropical Casino by IHG
3.5 out of 5
2701 Highway #2 Hostos Avenue, Mayagüez
Fully refundable
$173 nightly
The price is $192 total per night from Jul 20 to Jul 21
$192 total
Jul 20 - Jul 21
Total includes taxes and fees
9.2/10 Wonderful! (1,068 reviews)
"Nice hotel, clean, quiet,nice pool"

Reviewed on Jun 23, 2025

Holiday Inn Mayaguez and Tropical Casino by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santana Vacation Packages

Santana Essential Information

Language
Spanish
Currency
U.S dollars
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Rafael Hernandez Airport (BQN)

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Frequently asked questions

How much does a Santana vacation package cost?
You'll find cheap prices from $404 on Expedia for your Santana break. However, factors like the length of stay, the season and your choice of hotel will determine how much your vacation to Santana costs.
What are the cheapest months to go to Santana?
If you're looking to book a cheap Santana vacation package, consider visiting in September, October and December. You're likely to find lower rates on flights and hotels during these months --- perfect for a budget-friendly break.
How many days is enough for Santana?
Usually, a handful of days is enough to see the top attractions during your Santana vacation. However, if you'd like to have more time to rest or take day tours, think about extending your trip.
How to find the best Santana package deals?
Begin your search for a Santana package deal by entering your preferred trip dates and destination under our "Packages" tab. Then apply some filters, like "Guest rating" and "Property type," to fine-tune the results to your exact needs. You can also sort by "Package discount" and browse offers that come with unbeatable savings. If you don't find the ideal Santana package deal straight away, just change your dates and search again. Remember that deals are only available for a limited time, so book early and get your Santana escape underway.
Is it cheaper to book a Santana vacation as a package?
Expedia vacation packages are designed to help you keep more cash in your pocket. Bundle your car rental, flight and hotel into one great-value price and you could save hundreds of dollars. You'll usually snag a better deal than booking each component individually. And you'll still enjoy the flexibility to create a personalized Santana vacation by choosing your preferred accommodation type, airline and car class.
When to book a vacation package to Santana?
If you're planning an impromptu Santana getaway, browse our last-minute deals that can be booked up to one week before you go. Don't want to leave things to the last minute? You can find amazing deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Santana vacation packages?
If you're anything like us, you love traveling the world but are not a fan of the price tag that can come with it. That's why we offer Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Santana trip across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.