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Santana Vacation Rentals

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Check prices for these dates

In two weeks
Oct 23 - Oct 25
In two months
Dec 4 - Dec 6
In three months
Jan 1 - Jan 3
In four months
Jan 29 - Jan 31

Our top choices for Santana vacation rentals

A wooden table with a bottle of wine and two glasses on it, set against a white wall with green shutters.

1. Nature's Lodge Escape

Nature's Lodge Escape
Sabana Grande
8.0 out of 10, Very good, (7 reviews)
"Clean and organized, love the mountain view."
United States
Maria V.
$114 nightly
The price is $120
Oct 13 - Oct 14
Total with taxes and fees
Nature's Lodge Escape
A bedroom with a bed, bedside lamps, a sofa, a coffee table, and a door leading to a balcony.

2. Elegant 1-bedroom suite with pool and hot tub in historical Sabana Grande

Elegant 1-bedroom suite with pool and hot tub in historical Sabana Grande
Sabana Grande
$266 nightly
The price is $283
Oct 20 - Oct 21
Total with taxes and fees
Elegant 1-bedroom suite with pool and hot tub in historical Sabana Grande
A dining area with a wooden table, white chairs, and a ceiling fan.

3. Blue House Joyuda

Blue House Joyuda
3.5 star property
Cabo Rojo
9.6 out of 10, Exceptional, (54 reviews)
"Excelent place in front of the ocean, beautiful property"
United States
Samary
$121 nightly
The price is $130
Oct 12 - Oct 13
Total with taxes and fees
Blue House Joyuda
A covered outdoor area with a table and chairs, a hammock, and a view of greenery.

4. HighTide Guesthouse

HighTide Guesthouse
La Parguera
9.0 out of 10, Wonderful, (10 reviews)
"Nice, clean and exactly as pictured! Recommend -Will definitely visit again!"
United States
Aymee F.
$115 nightly
The price is $122
Oct 14 - Oct 15
Total with taxes and fees
HighTide Guesthouse
A beach with clear water, sandy shore, and trees.

5. Coastal Villa Arenas by Otium

Coastal Villa Arenas by Otium
2.0 star property
Boquerón
10.0 out of 10, Exceptional, (2 reviews)
"Loved everything about the property. Loved how cozy it was quiet location, etc. definitely will rent again. A bit hard to find it at night when we arrived but it was worth it."
United States
Melany
$175 nightly
The price is $191
Oct 15 - Oct 16
Total with taxes and fees
Coastal Villa Arenas by Otium
A wooden deck with a hot tub, a hammock, and a view of a town and hills.

6. Palmeras Beach Apartments

Palmeras Beach Apartments
3.0 star property
Guanica
10.0 out of 10, Exceptional, (21 reviews)
"Excellent location and place to stay for a relax and low key getaway… just need your belongings. "
United States
Sayra
$144 nightly
The price is $157
Oct 21 - Oct 22
Total with taxes and fees
Palmeras Beach Apartments
A modern bedroom with a bed, a TV on a dresser, a small plant, and a mirror.

7. High Tide Guesthouse PR

High Tide Guesthouse PR
Lajas
9.6 out of 10, Exceptional, (33 reviews)
"The room was clean and comfortable. Great place."
United States
SHIARA
$117 nightly
The price is $124
Oct 14 - Oct 15
Total with taxes and fees
High Tide Guesthouse PR
A covered outdoor area with a table and chairs, a hammock, and a view of greenery.

8. High Tide Guesthouse La Parguera, PR

High Tide Guesthouse La Parguera, PR
Lajas
8.6 out of 10, Excellent, (14 reviews)
"Is a very decent place to stay I gave 10 /10 and I recommend this to anybody you should give it a try your lover, especially for the surroundings"
United States
Luis
$116 nightly
The price is $123
Oct 12 - Oct 13
Total with taxes and fees
High Tide Guesthouse La Parguera, PR
A deck with wooden benches and tables, string lights, and a hot tub.

9. Enjoy a cozy space in a RV Camper w/hot tub, near beaches.

Enjoy a cozy space in a RV Camper w/hot tub, near beaches.
Lajas
9.8 out of 10, Exceptional, (13 reviews)
"Clean No too much time to enjoy the area Other neighbors friendly"
United States
Ed
$176 nightly
The price is $186
Oct 20 - Oct 21
Total with taxes and fees
Enjoy a cozy space in a RV Camper w/hot tub, near beaches.
A modern bedroom with a bed, a ceiling fan, a wall-mounted air conditioner, and a painting of a coastal landscape.

10. High Tide Guesthouse, Parguera

High Tide Guesthouse, Parguera
Lajas
9.6 out of 10, Exceptional, (18 reviews)
"Convenient location to La Parguera, my son and I were able to walk there! Nice outdoor area"
United States
Suzy Q.
$118 nightly
The price is $125
Oct 12 - Oct 13
Total with taxes and fees
High Tide Guesthouse, Parguera
A woman reading a magazine in a modern room with a staircase and potted plants.

11. 5.2 Loft • Lobby • Generator • Parking • 2nd Floor

5.2 Loft • Lobby • Generator • Parking • 2nd Floor
Mayagüez
10.0 out of 10, Exceptional, (1 review)
"That’s the cleanest place I’ve ever been. 10 out of 10, highly recommend."
United States
Felipe
$104 nightly
The price is $107
Oct 13 - Oct 14
Total with taxes and fees
5.2 Loft • Lobby • Generator • Parking • 2nd Floor
A modern living room with a glass coffee table, blue armchairs, a white cabinet, and a flat-screen TV mounted on the wall.

12. Cozy Home Close to Beaches

Cozy Home Close to Beaches
Cabo Rojo
8.4 out of 10, Very good, (5 reviews)
"We had an amazing stay! The house was beautiful, clean, and had everything we needed to feel right at home. The location was perfect—safe, peaceful, and close to everything we wanted to do. We absolutely loved the area and enjoyed exploring the neighborhood. . We would definitely stay here again and highly recommend it to anyone looking for a great place to stay!"
United States
Cynthia
$150 nightly
The price is $159
Oct 25 - Oct 26
Total with taxes and fees
Cozy Home Close to Beaches
A wooden bench with towels, a sign reading "CASITA MARY," and a wooden wall with a plant.

13. Casita Mary w/relaxing hot tub

Casita Mary w/relaxing hot tub
Cabo Rojo
9.6 out of 10, Exceptional, (4 reviews)
"Excellent place..Awesome host. He was the best, always asking if we were ok. Will visit again"
United States
Glorybell
$186 nightly
The price is $198
Oct 12 - Oct 13
Total with taxes and fees
Casita Mary w/relaxing hot tub
A modern A-frame building with a swimming pool, outdoor seating, and a wooden deck.

14. Africa787 | A-Frame Wood House W/Pool @ Lajas

Africa787 | A-Frame Wood House W/Pool @ Lajas
Lajas
7.0 out of 10, Good, (2 reviews)
"The house was super cute but very dark and not a lot of lighting. There was 2 lizards and a dead roach in the house and the neighborhood/area was pretty sketch. The pool is more of a jacquzzi but still very nice, but the jets didn’t work. Otherwise, it was nice and cold and private. "
United States
Leanette G.
$184 nightly
The price is $195
Oct 12 - Oct 13
Total with taxes and fees
Africa787 | A-Frame Wood House W/Pool @ Lajas
A balcony with wicker furniture, a hanging chair, and a view of a house and greenery.

15. 3.5 Near Beach • Generator • Hammock • 2nd floor

3.5 Near Beach • Generator • Hammock • 2nd floor
Miradero
8.0 out of 10, Very good, (1 review)
"Then properly was excellent for some reason my phone didn’t let me give the 5 ⭐️, excelente location and quite, Brangie was very attentive to our questions and request during our stay, the location is accessible to other areas within short distances, the only thing I would recommend is to have hot water since that was the only thing we didn’t had, from the rest everything was excellent. I would come back in a future"
United States
Marisol
$111 nightly
The price is $114
Nov 9 - Nov 10
Total with taxes and fees
3.5 Near Beach • Generator • Hammock • 2nd floor
A room with a green bed, a hammock, and a hanging light fixture.

16. 1.4 • Generator • 1st Floor • Parking • 238sf

1.4 • Generator • 1st Floor • Parking • 238sf
Mayagüez
10.0 out of 10, Exceptional, (1 review)
"Todo muy limpio, organizado, espectacular. Tiene todo lo que dice el anuncio, la verdad un 200% muy recomendada."
United States
Delyris
1.4 • Generator • 1st Floor • Parking • 238sf
A neatly arranged bedroom with a bed, a bedside table with a lamp, and a chair.

17. Boricua 3 | Cozy Eco-Stay w/ WiFi + A/C

Boricua 3 | Cozy Eco-Stay w/ WiFi + A/C
Rio Pietro
$199 nightly
The price is $219
Oct 12 - Oct 13
Total with taxes and fees
Boricua 3 | Cozy Eco-Stay w/ WiFi + A/C
A neatly made bed with white bedding, a dark headboard, and a bedside table with a lamp and a digital clock.

18. Cozy Yauco Studio | A/C + WiFi · Boricua 2

Cozy Yauco Studio | A/C + WiFi · Boricua 2
Yauco
$205 nightly
The price is $225
Oct 12 - Oct 13
Total with taxes and fees
Cozy Yauco Studio | A/C + WiFi · Boricua 2
A two-story building with a sign reading "LA PARROQUIA".

19. Cayo Laurel at Guayacan Guest House

Cayo Laurel at Guayacan Guest House
Lajas
10.0 out of 10, Exceptional, (23 reviews)
"Love my stay will stay again. "
United States
Nalany
$199 nightly
The price is $211
Oct 12 - Oct 13
Total with taxes and fees
Cayo Laurel at Guayacan Guest House
A clear turquoise sea with a sandy beach and mangrove trees on both sides.

20. Cayo Collado at Guayacán Guest House

Cayo Collado at Guayacán Guest House
Lajas
9.2 out of 10, Wonderful, (33 reviews)
"Host clean room oet firendly"
United States
Lucero R.
$130 nightly
The price is $138
Oct 15 - Oct 16
Total with taxes and fees
Cayo Collado at Guayacán Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santana Hotel Reviews

Parador Villa Parguera

Parador Villa Parguera

10/10 Excellent
"Clean room, excellent staff"
Gisselle 3-night trip
Posted 5 hours ago
Parador Villa Parguera

Find out more about Santana

Everything you need to know about Santana vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santana vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santana vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santana vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santana. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santana in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $120 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santana rentals

At Expedia, we put the best Santana vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santana rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santana vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santana. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santana?

Yes, we give you a choice of vacation rentals near popular points of interest in Santana, or you can go with a more remote option if you want a relaxing place to stay.

What's the top vacation rental that Santana has to offer?

Blue House Joyuda: This vacation home rental near Santana is located near the beach and has an outdoor pool, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a microwave, and a coffee maker.

What can I see and do in Santana?

While exploring the area, visit family-friendly sights like Surf 'N Fun Water Park, or get outside and enjoy nature at Bosque Estatal de Maricao. In the larger area, you’ll find Casa Morales and Church of Porta Coeli.

What are vacation rentals like in Santana?

Vacation rentals are privately owned accommodations you can stay in for a couple days or more in Santana. Vacation rentals feature amenities such as kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from shared hotel elevators and busy concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a great choice for family trips or small group gatherings.