Santiago Este Vacations from $664

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The Latest Santiago Este vacation packages

Price found within the past 48 hours. Click for updated prices.
Residencial Cristina

Residencial Cristina

2.5 out of 5
per person
Sep 5 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
7.2/10 Good! (5 reviews)
Central Hotel Bocas del Toro

Central Hotel Bocas del Toro

3 out of 5
Save 100% on your flight
per person
Sep 5 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
No reviews
Villa Botero By Casa Mojito B&B

Villa Botero By Casa Mojito B&B

3 out of 5
per person
Sep 28 - Oct 3
found 17 hours ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
9.8/10 Exceptional! (60 reviews)
Host was excellent. Great communication and very helpful. The rooms were nice and great value.

Reviewed on Apr 18, 2025

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4 out of 5
Casco Viejo
Save 100% on your flight
per person
Aug 16 - Aug 22
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Panama City (PTY)
9/10 Wonderful! (925 reviews)
Love the location and the restaurant inside the hotel was phenomenal.

Reviewed on Jul 11, 2025

Hotel Paraiso Caribeño

Hotel Paraiso Caribeño

3 out of 5
per person
Sep 5 - Sep 10
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to Panama City (PTY)
7.4/10 Good! (3 reviews)
Excellent staff Galvin Edgar Yuri Azizi and owner Andrea the best!!! Close to restaurants and Nice. Galvin fue muy lindo y atento y ademas que consiguio mejor tour para playa Estrella Lo recomiendo . Regresamos pronto gracias Ingrid C journalist

Reviewed on Mar 20, 2025

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Santiago Este Hotel Deals

Hotel Gran David

Hotel Gran David

3.5 out of 5
Vía Interamericana, Santiago, Veraguas
Fully refundableReserve now, pay when you stay
8.4/10 Very Good! (310 reviews)
"I did not like the stale smell in the room when I entered it and the smell was persistent."

Reviewed on Jun 12, 2025

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Hotel Gran David
Hotel Mykonos Panama

Hotel Mykonos Panama

3.5 out of 5
Panamerican Highway, in front of Ruben Cantu Airport, Nuevo Santiago, Veraguas
Fully refundableReserve now, pay when you stay
$81 nightly
The price is $90 total per night from Aug 14 to Aug 15
$90 total
Aug 14 - Aug 15
Total includes taxes and fees
8.8/10 Excellent! (518 reviews)
"Great location and service."

Reviewed on Jun 28, 2025

Hotel Mykonos Panama
HOTEL VISTA LAGO

HOTEL VISTA LAGO

3 out of 5
Rincón Largo, La Pena, Santiago de Veraguas
Fully refundableReserve now, pay when you stay
$77 nightly
The price is $84 total per night from Jul 16 to Jul 17
$84 total
Jul 16 - Jul 17
Total includes taxes and fees
9.2/10 Wonderful! (60 reviews)
"Very clean, food was 10/10"

Reviewed on Jul 10, 2025

HOTEL VISTA LAGO
See all 13 properties in Santiago Este
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santiago Este Vacation Packages

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Frequently asked questions

How to find the best Santiago Este package deals?
Bagging a cheap Santiago Este package deal is a cinch with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your budget, apply a few filters and see what's available. You can personalize your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to discover the most economical Santiago Este package deals. Want a simple trick to get the biggest savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are usually lower.
When to book a vacation package to Santiago Este?
If you're planning a spontaneous Santiago Este vacation, check out our last-minute deals that can be booked up to a week before you go. Don't want to leave things to the last minute? You can find amazing deals on your flights and hotels by booking ahead.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.