Santiago Vacations from $249

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The Latest Santiago Vacation Packages

Price found within the past 48 hours. Click for updated prices.

OYO Hotel Trigos De Oro,San Luis Teolocholco Park

$249

per person

Dec 3 - Dec 7

found 23 hours ago

Roundtrip flight included

Monterrey (MTY) to Puebla (PBC)

8.8/10 Excellent! (11 reviews)

Great staff !! Clean And quiet place !! And close from Tlaxcala

Reviewed on Jun 21, 2025

Xoxula by Inmense

Cholula

Save 100% on your flight

$431

per person

Dec 25 - Dec 28

found 21 hours ago

Roundtrip flight included

Monterrey (MTY) to Puebla (PBC)

9/10 Wonderful! (200 reviews)

La habitación era amplia y estaba limpia. El desayuno incluído es sencillo pero tienen buen sazón. El personal que atiende muy amable y servicial. La ubicación es excelente para visitar el centro histórico caminando. El hotel no cuenta con estacionamiento, pero hay cajones en la calle (con parquímetro) y un estacionamiento justo en la esquina. Hay varios restaurantes y otros hoteles en esa misma cuadra, por lo que pudiera resultar molesto para los que tienen el sueño muy ligero. Nosotros dormimos bastante bien.

Reviewed on Jul 28, 2026

Capital O Hotel Boutique Las Torres

Save 100% on your flight

$367

per person

Nov 16 - Nov 22

found 1 day ago

Roundtrip flight included

Tijuana (TIJ) to Puebla (PBC)

9.2/10 Wonderful! (89 reviews)

Friendly staff

Reviewed on Jul 11, 2026

Alquería de Carrión Hotel Boutique

Save 100% on your flight

$340

per person

Dec 25 - Dec 28

found 19 hours ago

Roundtrip flight included

Monterrey (MTY) to Puebla (PBC)

9.6/10 Exceptional! (95 reviews)

Capital O Hotel Emperadores Inn, Atlixco

$261

per person

Dec 3 - Dec 7

found 23 hours ago

Roundtrip flight included

Monterrey (MTY) to Puebla (PBC)

7/10 Good! (238 reviews)

Where to stay in Santiago

Find the best Santiago areas and neighborhoods for the activities you enjoy most. Learn more about Santiago

A historic street with ornate buildings, a prominent dome, and a red building with balconies.

Puebla Historic Center

5 out of top 10 points of interest in this area

Discover a World Heritage Site filled with colonial buildings in the Historic Monuments Zone, where you can explore Barrio de los Sapos, Barrio del Artista, and the stunning Puebla Cathedral.

A cityscape with prominent historical architecture, including a cathedral with a golden dome and two tall towers.

Angelópolis

1 out of top 10 points of interest in this area

The neighborhood boasts luxurious residential developments, cultural spaces, and parks. Explore attractions like La Estrella de Puebla, The Art Park, and the Baroque Museum, or shop at Centro Comercial Angelópolis.

A church on a hill with a volcano in the background.

Cholula

1 out of top 10 points of interest in this area

Best known for its Great Pyramid and numerous churches, Cholula features the Iglesia de Nuestra Señora de los Remedios sanctuary atop the pyramid. Explore the city's eighteen distinct barrios, each with a patron saint.

A series of arches with a patterned ceiling.

Cholula Centro

While visiting Cholula Centro, you might make a stop by sights like Plaza de la Concordia and San Gabriel Convent.

A snow-capped mountain with a forested foreground.

Chipilo

While Chipilo isn't home to many top sights, La Virgen de los Remedios Sanctuary and Plaza de la Concordia are some notable places to visit nearby.

Santiago Hotel Deals

Holiday Inn Express Puebla by IHG

Blvd. Hermanos Serdan 45 Puebla PUE

Fully refundableReserve now, pay when you stay

$65 nightly

$77 total

Oct 25 - Oct 26

Total with taxes and fees

Camino Real Puebla Angelopolis

Boulevard Atlixcayotl Km 5 San Andrés Cholula PUE

Fully refundableReserve now, pay when you stay

$67 nightly

$81 total

Oct 28 - Oct 29

Total with taxes and fees

Four Points By Sheraton Puebla

Boulevard Hermanos Serdssn No 102 Puebla PUE

Fully refundableReserve now, pay when you stay

$60 nightly

$71 total

Oct 26 - Oct 27

Total with taxes and fees

See all 773 properties in Santiago

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.