Santiago Vacations from $315

Book a Hotel + Flight or Car together to unlock savings

The Latest Santiago Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Capital O Hotel Emperadores Inn, Atlixco

$315

per person

Oct 29 - Nov 3

found 1 day ago

Roundtrip flight included

Monterrey (MTY) to Puebla (PBC)

7/10 Good! (235 reviews)

Habitación amplia, limpia, una cama suave, pero firme, agua caliente y servicio de tv

Reviewed on Aug 5, 2026

Casona María

Puebla Historic Center

Save 100% on your flight

$382

per person

Oct 29 - Nov 3

found 1 day ago

Roundtrip flight included

Monterrey (MTY) to Puebla (PBC)

9.4/10 Exceptional! (484 reviews)

Capital O Hotel Boutique Las Torres

Save 100% on your flight

$411

per person

Nov 3 - Nov 10

found 1 day ago

Roundtrip flight included

Tijuana (TIJ) to Puebla (PBC)

9.2/10 Wonderful! (86 reviews)

Friendly staff

Reviewed on Jul 11, 2026

OYO Hotel Trigos De Oro,San Luis Teolocholco Park

$352

per person

Nov 3 - Nov 10

found 1 day ago

Roundtrip flight included

Tijuana (TIJ) to Puebla (PBC)

8.8/10 Excellent! (11 reviews)

Great staff !! Clean And quiet place !! And close from Tlaxcala

Reviewed on Jun 21, 2025

Grand Fiesta Americana Puebla Angelópolis

Angelópolis

Save 100% on your flight

$780

per person

Oct 29 - Nov 3

found 13 hours ago

Roundtrip flight included

Monterrey (MTY) to Puebla (PBC)

9.6/10 Exceptional! (1,004 reviews)

Excelente servicio. El mejor hotel de Puebla

Reviewed on Aug 16, 2026

Where to stay in Santiago

Find the best Santiago areas and neighborhoods for the activities you enjoy most. Learn more about Santiago

A historic street with ornate buildings, a prominent dome, and a red building with balconies.

Puebla Historic Center

4 out of top 10 points of interest in this area

Discover a World Heritage Site filled with colonial buildings in the Historic Monuments Zone, where you can explore Barrio de los Sapos, Barrio del Artista, and the stunning Puebla Cathedral.

A cityscape with prominent historical architecture, including a cathedral with a golden dome and two tall towers.

Angelópolis

2 out of top 10 points of interest in this area

The neighborhood boasts luxurious residential developments, cultural spaces, and parks. Explore attractions like La Estrella de Puebla, The Art Park, and the Baroque Museum, or shop at Centro Comercial Angelópolis.

A church on a hill with a volcano in the background.

Cholula

1 out of top 10 points of interest in this area

Best known for its Great Pyramid and numerous churches, Cholula features the Iglesia de Nuestra Señora de los Remedios sanctuary atop the pyramid. Explore the city's eighteen distinct barrios, each with a patron saint.

A church with a mural of a robed figure and a cross, surrounded by stone buildings.

La Paz

While La Paz isn't home to many top sights, Galerías Serdán and Triangulo Las Animas Shopping Center are some notable places to visit nearby.

A series of arches with a patterned ceiling.

Cholula Centro

While visiting Cholula Centro, you might make a stop by sights like Plaza de la Concordia and San Gabriel Convent.

Santiago Hotel Deals

Holiday Inn Express Puebla by IHG

Blvd. Hermanos Serdan 45 Puebla PUE

$56 nightly

$67 total

Sep 21 - Sep 22

Total with taxes and fees

9.4/10 Exceptional! (2,053 reviews)

"Everything was super organized delicious breakfast, also smelly super clean."

Reviewed on Aug 19, 2026

Camino Real Puebla Angelopolis

Boulevard Atlixcayotl Km 5 San Andrés Cholula PUE

Fully refundableReserve now, pay when you stay

$69 nightly

$83 total

Sep 13 - Sep 14

Total with taxes and fees

Four Points By Sheraton Puebla

Boulevard Hermanos Serdssn No 102 Puebla PUE

$59 nightly

$70 total

Aug 30 - Aug 31

Total with taxes and fees

See all 740 properties in Santiago

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.