Santo Isidoro Vacations from $756

Book a Hotel + Flight or Car together to unlock savings

Photo by Joao Santana

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to $1,045 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Your Santo Isidoro Vacation

Lock in a Santo Isidoro vacation package that includes everything you need without any unnecessary extras. Good for nature, adventure sports and walking, think about basing yourself in the neighborhood of Terrujem. Make your trip to Santo Isidoro even more exciting by including some sightseeing. Mafra National Palace, Foz de Lizandro Beach and São Lourenço Beach are among the leading attractions worth exploring. A couple of clicks is all it takes to craft a tailored Santo Isidoro vacation on Expedia.

The Latest Santo Isidoro Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Les Deux Mariettes Apartments & Suites

Les Deux Mariettes Apartments & Suites

4 out of 5
Lisbon City Center
Price was $1,105, price is now $756 per person
$756
per person
Dec 7 - Dec 13
found 1 hour ago
Roundtrip non-stop flight included
New York (JFK) to Lisbon (LIS)
9.6/10 Exceptional! (105 reviews)
The hotel was conveniently located, the service was great, and the apartment was clean and modern.

Reviewed on Sep 8, 2025

ORIENTE DNA STUDIOS X

ORIENTE DNA STUDIOS X

3 out of 5
Moscavide
Price was $1,460, price is now $1,057 per person
$1,057
per person
Nov 9 - Nov 14
found 22 hours ago
Roundtrip non-stop flight included
New York (NYC) to Lisbon (LIS)
2/10 (1 review)
Longevity Senses - Cascais Boutique Hotel - Adults Only

Longevity Senses - Cascais Boutique Hotel - Adults Only

5 out of 5
Quinta da Marinha
Price was $1,421, price is now $1,032 per person
$1,032
per person
Nov 9 - Nov 15
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Lisbon (LIS)
9/10 Wonderful! (12 reviews)
Top notch, excellent service, gorgeous oceanfront property. I recommend this hotel to those with a very very very high expectations.

Reviewed on Sep 7, 2025

TURIM Boulevard Hotel – Adults Only

TURIM Boulevard Hotel – Adults Only

5 out of 5
Lisbon City Center
Price was $1,144, price is now $776 per person
$776
per person
Dec 8 - Dec 13
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Lisbon (LIS)
9/10 Wonderful! (377 reviews)
Friendly staff, good breakfast, excellent location

Reviewed on Sep 26, 2025

Casa Rosário : Three Bedroom Villa with Private Pool;

Casa Rosário : Three Bedroom Villa with Private Pool;

4 out of 5
Price was $1,290, price is now $885 per person
$885
per person
Nov 7 - Nov 10
just found
Roundtrip non-stop flight included
New York (NYC) to Lisbon (LIS)
4/10 (1 review)

Where to stay in Santo Isidoro

Find the best Santo Isidoro areas and neighborhoods for the activities you enjoy most. Learn more about Santo Isidoro
Lisbon showing views, chateau or palace and a city

Lisbon City Center

7 out of top 10 points of interest in this area

Travelers love Lisbon City Center for its popular shops, and you can see more of Lisbon by jumping on the metro at Saldanha Station or Sao Sebastiao Station. You might spend time checking out top sights like Avenida da Liberdade and Rossio Square.

Find hotels in Lisbon City Center

Santo Isidoro Hotel Deals

Immerso Hotel, a Member of Design Hotels

Immerso Hotel, a Member of Design Hotels

5 out of 5
Rua Bica da Figueira, Mafra
Fully refundableReserve now, pay when you stay
$245 nightly
The price is $262 total per night from Nov 6 to Nov 7
$262 total
Nov 6 - Nov 7
Total with taxes and fees
9.6/10 Exceptional! (44 reviews)
"Beautiful hotel in a peaceful location with amazing views of the sea"

Reviewed on Sep 11, 2025

Immerso Hotel, a Member of Design Hotels
B&B Hotel Lisboa Aeroporto

B&B Hotel Lisboa Aeroporto

3 out of 5
Rua Vasco da Gama 5, Portela, Loures, Lisbon
Fully refundableReserve now, pay when you stay
$65 nightly
The price is $73 total per night from Nov 2 to Nov 3
$73 total
Nov 2 - Nov 3
Total with taxes and fees
8.4/10 Very Good! (441 reviews)
"*"

Reviewed on Oct 5, 2025

B&B Hotel Lisboa Aeroporto
EVOLUTION Cascais-Estoril Hotel

EVOLUTION Cascais-Estoril Hotel

4 out of 5
Avenida Marginal 7034, Estoril, Cascais
Fully refundableReserve now, pay when you stay
$133 nightly
The price is $150 total per night from Nov 1 to Nov 2
$150 total
Nov 1 - Nov 2
Total with taxes and fees
9.4/10 Exceptional! (476 reviews)
"Excellent Food and Drinks. Rooftop pool and bar has amazing views. Room with a view was clean and comfortable! Included in the stay was the spa pool, sauna, steam shower and sensory shower for a relaxing break."

Reviewed on Oct 2, 2025

EVOLUTION Cascais-Estoril Hotel
See all 2,250 properties in Santo Isidoro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Santo Isidoro

Avenida da Liberdade featuring a city and a statue or sculpture

Avenida da Liberdade

You can browse for souvenirs when you visit Avenida da Liberdade, a popular shopping spot in Santo Antonio. Discover the charming cafes in this family-friendly area, or seek out the local tours.

Avenida da Liberdade
Belem Tower which includes a sunset, heritage architecture and a bridge

Belém Tower

4.5/5(1,337 reviews)

Lisbon constructed a fortification along a waterway to defend its riches. Now access the structure from the shore for lovely views.

Belém Tower
Lisbon City Center showing a monument and a statue or sculpture

Marquis of Pombal Square

4.5/5(254 reviews)

Crowned by a statue of a Portuguese reformer, this bustling traffic hub is a gateway to a lush city park and one of Lisbon’s chicest avenues.

Marquis of Pombal Square

Things to do

Hop-On Hop-Off Yellow Boat Tour

Hop-On Hop-Off Yellow Boat Tour

$28
per adult
72% of travellers recommend
Hop-On Hop-Off Yellow Boat Tour
Lisbon: Sunset on board with music & drinks

Lisbon: Sunset on board with music & drinks

$19
per adult
Lisbon: Sunset on board with music & drinks
Sunset tour in Lisbon

Sunset Boat Tour in Lisbon with Wine

$53
per adult
Sunset Boat Tour in Lisbon with Wine
See all activities in Lisbon District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.