Santopadre Vacations from $719

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Santopadre Vacation

Build a custom vacation package to Santopadre and start looking forward to your next epic adventure. Base yourself in the neighborhood of Colle Carino, which is good for nature and views, for a real taste of this exciting city. Make your trip to Santopadre even more exciting by including some sightseeing. Castello dei Conti dAquino, Cascata Grande and Parco Archeologico di Fregellae are some of the leading attractions you'll want to explore. Check out Expedia's extensive range of travel options and begin planning your dream vacation to Santopadre now.

The Latest Santopadre vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Delle Civette

Hotel Delle Civette

3 out of 5
Nomentano
Price was $1,137, price is now $719 per person
$719
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.6/10 Exceptional! (267 reviews)
Excelente lugar en una area muy tranquila y cerca de lugares para ir a comer o cenar, su personal muy amable elvis, Diego todo si personal .🙏🙏🙏

Reviewed on Jan 17, 2026

Albergo Etico Roma

Albergo Etico Roma

3 out of 5
Flaminio
Save 100% on your flight
Price was $1,363, price is now $895 per person
$895
per person
Mar 13 - Mar 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.6/10 Exceptional! (335 reviews)
Wonderful stay, would be back

Reviewed on Dec 16, 2025

Relais Trevi 95 Boutique Hotel

Relais Trevi 95 Boutique Hotel

4 out of 5
Rome City Centre
Price was $1,459, price is now $1,099 per person
$1,099
per person
Mar 13 - Mar 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Rome (FCO)
9.4/10 Exceptional! (1,000 reviews)
Loation, location, location.

Reviewed on Jan 4, 2026

Relais de la Poste

Relais de la Poste

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,619, price is now $1,429 per person
$1,429
per person
Apr 1 - Apr 6
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to Rome (FCO)
9.2/10 Wonderful! (612 reviews)
Couldn't ask for a better location! Delicious breakfast, beautiful room and friendly staff.

Reviewed on Jan 19, 2026

Charme Spagna Boutique Hotel

Charme Spagna Boutique Hotel

3 out of 5
Rome City Centre
Save 100% on your flight
Price was $2,585, price is now $1,715 per person
$1,715
per person
Mar 27 - Apr 2
found 12 hours ago
Roundtrip non-stop flight included
Los Angeles (LAX) to Rome (FCO)
9.2/10 Wonderful! (208 reviews)
Annexed Room came with a balcony, comfy bed, and a nice bathroom. Fairly quiet and peaceful to relax in after walking around Rome all day.

Reviewed on Jan 8, 2026

Don't see what you're looking for?
See all available trips from Columbus to Santopadre
View all trips

Santopadre Hotel Deals

Hotel Orso Bianco

Hotel Orso Bianco

3 out of 5
Via Collacchi 1 Pescasseroli AQ
8.6/10 Excellent! (78 reviews)
Perfect Peaceful Panoramic Place! Two minutes drive from town, five minutes by bike or a 25 minute walk. Simple breakfast sweet or savoury. Options to have lunch/dinner or enjoy a delightful Aperol on the terrace! Helpful, kind and friendly staff. Super clean! Ideal getaway for resetting your mind ...

Reviewed on Jul 8, 2025

Get rates
Hotel Orso Bianco
Edra Palace

Edra Palace

4 out of 5
Via Ausonia angolo via Cerro Cassino FR
Fully refundableReserve now, pay when you stay
9/10 Wonderful! (166 reviews)
The staff was incredibly sweet and accommodating to our kids. Everything was clean and as it should be if a little outdated. The Christmas decorations in the lobby and garden were a real plus for the kids. Our waiter was especially wonderful at dinner and breakfast I wish i remembered his name. Great ...

Reviewed on Nov 29, 2025

Get rates
Edra Palace
LH Hotel il Picchio

LH Hotel il Picchio

4 out of 5
Via Valle dell'Oro 2 Pescasseroli AQ
$77 nightly
The price is $87 total per night from Feb 10 to Feb 11
$87 total
Feb 10 - Feb 11
Total with taxes and fees
6.4/10 (5 reviews)
Struttura spaziosa, personale cortese, unica pecca è che non funzionava il frigobar ed era presente un problema alla fogna che non dava problemi evidenti ma se scaricavi l'acqua fuoriusciva leggermente dalla doccia.

Reviewed on Sep 19, 2025

LH Hotel il Picchio
See all 328 properties in Santopadre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santopadre Vacation Packages

Santopadre Essential Information

Language
Italian
Currency
Euros
Local Welcome
Ciao
Local Goodbye
Ciao
Population
400
Top Sights
Cascata Grande, Pastena Caves and Castello dei Conti dAquino

More vacations you might like

All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Frequently asked questions

How much does a Santopadre vacation package cost?
Offering excellent value package deals from $719 on Expedia, you'll be pleasantly surprised at how much a vacation to Santopadre costs! Our packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Santopadre?
You can generally find reduced prices and better availability in November, December and January. Take a look at our cheap Santopadre vacation packages and you could get some great off-season deals.
How many days is enough for Santopadre?
Usually, a handful of days is enough to see the top sights during your Santopadre vacation. However, if you want to have more time to relax or go on day tours, think about extending your itinerary.
How to find the best Santopadre package deals?
Use Expedia's handy filters to find some great Santopadre package deals. When you begin your search, simply set your maximum budget and then sort the results by "Price: low to high." If you want to save, plan your adventure for midweek, or search for Santopadre package deals in the low season. Play around with your travel dates and you may score even better discounts. As a rule of thumb, it's typically best to book your vacation package as soon as possible.
Is it cheaper to book a Santopadre vacation as a package?
You can enjoy significant savings on your Santopadre retreat by booking a customized vacation package. Check the "Package" heading, then select your travel dates and destination to browse some great hotel and flight prices. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to Santopadre?
If you've got your Santopadre travel dates finalized, book as early as you can to bag some incredible deals. With Expedia, you can often reserve some flights up to a year in advance. Prefer spontaneous adventures? Our last-minute deals are perfect for setting off on a whim.
Does Expedia offer Book Now, Pay Later Santopadre vacation packages?
Set off on your dream trip to Santopadre with Expedia's Book Now, Pay Later vacations. There's no need to save like crazy or hold off until your next payday — we've partnered with online lender Affirm to give you flexibility and choice. Our vacation packages with payment plans allow you to split the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, you can easily budget for your trip and snag great deals before they sell out.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.