Siesta Isle Vacations from $238

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Your Siesta Isle Vacation

Immerse yourself in the best that Siesta Isle has to offer with a Siesta Isle vacation package. From its nature to every other thing that sets it apart, this neighborhood will captivate you from start to finish. Some leading nearby attractions to see during your trip to Siesta Isle include Fishing Pier Fort Myers Beach, Bunche Beach and Jungle Golf Ft. Myers. Stop daydreaming and start doing. When you're ready to book your ideal vacation to Siesta Isle, Expedia is here to help.

The Latest Siesta Isle Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hyatt Place Fort Myers/at The Forum
Hilton Garden Inn Ft Myers
LaPlaya Beach & Golf Resort - A Noble House Resort
Edison Beach House
The Perry Hotel Naples

Where to stay in Siesta Isle

Find the best Siesta Isle areas and neighborhoods for the activities you enjoy most. Learn more about Siesta Isle

Siesta Isle Hotel Deals

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 out of 5
17990 San Carlos Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $113 total per night from Jul 13 to Jul 14
$113 total
Jul 13 - Jul 14
Total includes taxes and fees
8.6/10 Excellent! (1,001 reviews)
"Conveniente"

Reviewed on Jul 7, 2025

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Lani Kai Beachfront Resort
Lani Kai Beachfront Resort
3.5 out of 5
1400 Estero Blvd, Fort Myers Beach, FL
Fully refundableReserve now, pay when you stay
$229 nightly
The price is $256 total per night from Jul 13 to Jul 14
$256 total
Jul 13 - Jul 14
Total includes taxes and fees
8.4/10 Very Good! (1,027 reviews)
Enjoyable beach stay
"Room was very clean and spacious. Comfortable king size bed, nice balcony and great ocean view. Entertainment each evening with music. Price of milk shake a bit high, but I guess that’s expected at the beach. Breakfast was good and service was awesome."

Reviewed on Jul 9, 2025

Lani Kai Beachfront Resort
Sanibel Island Beach Resort
Sanibel Island Beach Resort
3 out of 5
1231 Middle Gulf Dr, Sanibel, FL
Fully refundableReserve now, pay when you stay
$231 nightly
The price is $255 total per night from Aug 10 to Aug 11
$255 total
Aug 10 - Aug 11
Total includes taxes and fees
8.8/10 Excellent! (1,190 reviews)
"Excellent location"

Reviewed on Jul 7, 2025

Sanibel Island Beach Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Siesta Isle

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.