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Discover Siesta Isle hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Deluxe Studio, 1 King Bed, Marina View | View from room
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2.5 star property
Siesta Isle
8.8 out of 10, Excellent, (1005)
"Great Place to Stay!"
United States
JUDY
$98 nightly
The price is $110
Nov 23 - Nov 24
Total with taxes and fees
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

4.0 star property
3.6 mi from Siesta Isle
8.4 out of 10, Very Good, (1010)
"This was thr best place that we have ever stayed at. "
United States
Matthew
$221 nightly
The price is $247
Nov 30 - Dec 1
Total with taxes and fees
Marriott Sanibel Harbour Resort & Spa
Interior entrance
Allure Suites

Allure Suites

3.0 star property
6.4 mi from Siesta Isle
7.6 out of 10, Good, (1007)
"Was clean staff was very nice"
United States
Richard J
$55 nightly
The price is $62
Nov 23 - Nov 24
Total with taxes and fees
Allure Suites
Terrace/patio
Hampton Inn Bonita Springs/Naples-North

Hampton Inn Bonita Springs/Naples-North

2.5 star property
13.6 mi from Siesta Isle
9.0 out of 10, Wonderful, (1002)
"Very nice hotel and staff."
United States
arthur
$103 nightly
The price is $115
Nov 30 - Dec 1
Total with taxes and fees
Hampton Inn Bonita Springs/Naples-North
Outdoor pool
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

3.0 star property
1.6 mi from Siesta Isle
8.6 out of 10, Excellent, (1003)
"Clean room, wonderful staff, and nice breakfast. "
United States
Danielle
$95 nightly
The price is $106
Dec 1 - Dec 2
Total with taxes and fees
Residence Inn by Marriott Fort Myers Sanibel
Lobby
Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites

2.5 star property
10.9 mi from Siesta Isle
8.8 out of 10, Excellent, (1080)
"Service was great, cleanliness was good ad well, really enjoyed breakfast"
United States
Tina
$71 nightly
The price is $79
Nov 23 - Nov 24
Total with taxes and fees
Best Western Fort Myers Inn & Suites
Property amenity
Comfort Suites Fort Myers East I-75

Comfort Suites Fort Myers East I-75

2.5 star property
15.8 mi from Siesta Isle
9.6 out of 10, Exceptional, (331)
"Friendly staff, great breakfast, clean room. "
United States
Shellie
$96 nightly
The price is $107
Nov 30 - Dec 1
Total with taxes and fees
Comfort Suites Fort Myers East I-75
Lobby
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

2.0 star property
11.4 mi from Siesta Isle
8.0 out of 10, Very Good, (1488)
"Clean, comfortable and quiet facility… I would stay here again!"
United States
John
$69 nightly
The price is $77
Nov 23 - Nov 24
Total with taxes and fees
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Property amenity
TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero

3.5 star property
10.7 mi from Siesta Isle
9.4 out of 10, Exceptional, (453)
"Perfect Stay!"
Brazil
Bruno
$125 nightly
The price is $139
Nov 29 - Nov 30
Total with taxes and fees
TownePlace Suites by Marriott Fort Myers Estero
View from room
Courtyard by Marriott Fort Myers Cape Coral

Courtyard by Marriott Fort Myers Cape Coral

3.0 star property
10.7 mi from Siesta Isle
8.2 out of 10, Very Good, (1004)
"Was a terrific stay and they went out of their way to accommodate my injured dog even giving us a late checkout "
United States
laura
$79 nightly
The price is $88
Dec 22 - Dec 23
Total with taxes and fees
Courtyard by Marriott Fort Myers Cape Coral
Outdoor pool
Hampton Inn & Suites Fort Myers - Colonial Blvd

Hampton Inn & Suites Fort Myers - Colonial Blvd

2.5 star property
11 mi from Siesta Isle
9.4 out of 10, Exceptional, (1001)
"Clean room, friendly staff, nice breakfast"
United States
Mercedes
$106 nightly
The price is $118
Nov 30 - Dec 1
Total with taxes and fees
Hampton Inn & Suites Fort Myers - Colonial Blvd
Exterior
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

3.0 star property
1.4 mi from Siesta Isle
8.0 out of 10, Very Good, (1005)
"Great place to stay and breakfast was delicious "
United States
Keishly
$93 nightly
The price is $103
Nov 24 - Nov 25
Total with taxes and fees
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
Exterior
Best Western Fort Myers Waterfront

Best Western Fort Myers Waterfront

3.0 star property
13.4 mi from Siesta Isle
7.4 out of 10, Good, (1005)
"Great hospitality. Perfect view on the water. Great restaurant on site and IHOP next door. "
United States
Carol
$101 nightly
The price is $113
Nov 23 - Nov 24
Total with taxes and fees
Best Western Fort Myers Waterfront
Outdoor pool
Homewood Suites by Hilton Bonita Springs

Homewood Suites by Hilton Bonita Springs

3.0 star property
12.6 mi from Siesta Isle
9.0 out of 10, Wonderful, (1012)
"The staff was great and the hotel was amazing "
United States
Jeanice
$103 nightly
The price is $115
Nov 30 - Dec 1
Total with taxes and fees
Homewood Suites by Hilton Bonita Springs
Pool
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

3.5 star property
12.7 mi from Siesta Isle
8.6 out of 10, Excellent, (832)
"Staff was friendly. "
United States
Jennifer
$139 nightly
The price is $155
Dec 1 - Dec 2
Total with taxes and fees
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
Interior entrance
Candlewood Suites Ft Myers I-75 by IHG

Candlewood Suites Ft Myers I-75 by IHG

2.5 star property
13.5 mi from Siesta Isle
8.0 out of 10, Very Good, (741)
"The suite is equipped with everything you need."
United States
Elizabet
$69 nightly
The price is $77
Nov 30 - Dec 1
Total with taxes and fees
Candlewood Suites Ft Myers I-75 by IHG
Exterior
Hyatt Place Fort Myers/at The Forum

Hyatt Place Fort Myers/at The Forum

3.0 star property
14.4 mi from Siesta Isle
8.2 out of 10, Very Good, (1008)
"Goodlocation"
United States
Mary Michael
$93 nightly
The price is $103
Nov 25 - Nov 26
Total with taxes and fees
Hyatt Place Fort Myers/at The Forum
Exterior
Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs

3.0 star property
12.7 mi from Siesta Isle
8.8 out of 10, Excellent, (684)
"We enjoyed our stay. The accommodations were great!"
United States
Conny
$109 nightly
The price is $121
Nov 24 - Nov 25
Total with taxes and fees
Latitude 26 Waterfront Boutique Resort - Bonita Springs
Garden
Travelodge by Wyndham Fort Myers North

Travelodge by Wyndham Fort Myers North

2.0 star property
13.6 mi from Siesta Isle
5.8 out of 10, (1001)
"Great place to stay "
United States
Blaine
$48 nightly
The price is $54
Nov 30 - Dec 1
Total with taxes and fees
Travelodge by Wyndham Fort Myers North
Property amenity
MainStay Suites Fort Myers East I-75

MainStay Suites Fort Myers East I-75

2.5 star property
15.8 mi from Siesta Isle
9.6 out of 10, Exceptional, (203)
"Overall good hotel for a reasonable price "
United States
Carolyn
$94 nightly
The price is $104
Nov 29 - Nov 30
Total with taxes and fees
MainStay Suites Fort Myers East I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Siesta Isle

Find the best Siesta Isle areas and neighborhoods for the activities you enjoy most.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

Laguna Shores

Though Laguna Shores might not have many top sights, you can venture to the surrounding area to see attractions like Lover's Key Beach and Santini Marina Shopping Plaza.

Top Siesta Isle Hotel Reviews

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

10/10 Excellent
"Great and clean room. The front desk people were very nice friendly and helpful the restaurant was good and the coffee shop and the beach maintenance was superb."
Rebecca 3-night trip
Posted 16 hours ago
Lani Kai Beachfront Resort

Frequently asked questions

What are the best family hotels in Siesta Isle?
Latitude 26 Waterfront Boutique Resort in Fort Myers Beach is a fantastic choice for families seeking a relaxing getaway filled with adventure. This charming hotel boasts a inviting space and offers an impressive array of amenities designed with both comfort and fun in mind.
What hotels in Siesta Isle offer free breakfast?
Latitude 26 Waterfront Boutique Resort in Fort Myers Beach is a charming option for travelers seeking a delightful getaway. This hotel, boasting an impressive 8.8 review score, offers guests the convenience of a complimentary continental breakfast, great for fueling up before a day of adventure.
What are the best budget hotels in Siesta Isle?
Latitude 26 Waterfront Boutique Resort in Fort Myers Beach is an inviting option for families and budget-conscious travelers alike. Guests appreciate the charming ambiance, complete with a beautiful outdoor pool area great for a day of relaxation. The resort offers a variety of amenities designed to enhance your stay, including free Wi-Fi, complimentary breakfast, and free self-parking, ensuring both convenience and comfort.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Siesta Isle.
How can I save on a Siesta Isle hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Siesta Isle hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Siesta Isle hotel?
Hotel prices in Siesta Isle often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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