South Main Vacations from $360

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Your South Main Vacation

Book your vacation package to South Main and get ready to explore its nightlife and plenty more. Whether you're looking for adventure or relaxation, you'll discover it in this sought-after neighborhood. Can't wait to head out and see the sights during your trip to South Main? Don't miss nearby attractions like Orpheum Theatre, Sun Studio and Stax Museum of American Soul Music. Expedia will help you turn your dream South Main vacation into reality, whatever your travel plans or budget.

The Latest South Main Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Home2 Suites by Hilton Memphis East Germantown

Home2 Suites by Hilton Memphis East Germantown

3 out of 5
per person
Sep 21 - Sep 24
found 20 hours ago
Roundtrip flight included
New York (NYC) to Memphis (MEM)
8.8/10 Excellent! (131 reviews)
The location is excellent and easy to find if you have the complete address. However, MapQuest was unable to locate the location given in my itinerary. Please check your website and ensure your partners, such as Expedia, have the correct information.

Reviewed on Jul 10, 2025

Hotel Napoleon Memphis

Hotel Napoleon Memphis

4 out of 5
Downtown Memphis
per person
Aug 14 - Aug 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Memphis (MEM)
8.6/10 Excellent! (915 reviews)
The pictures of this hotel are significantly better than how the hotel actually looks. It’s a nice hotel overall but some areas are dated and need fresh paint. When I stayed here I was told the bar/restaurant was being renovated so it would be only open for the continental breakfast. The “breakfast” consisted of stale danishes, muffins, juice, granola and yogurt. No serving utensils and an extremely limited amount. Once the single platefuls were gone, they stated that was all they had, regardless of how many guests they had. Parking was in a deck next door and was an inconvenience because you have to call or text the company to be let out of the gate each time you had to exit. Overall it’s a decent hotel and I would stay here again only for 1 or 2 days.

Reviewed on Jun 28, 2025

Barsala At The Nine @ Memphis

Barsala At The Nine @ Memphis

4 out of 5
East Memphis
per person
Sep 4 - Sep 7
found 10 hours ago
Roundtrip flight included
New York (NYC) to Memphis (MEM)
No reviews
River Inn of Harbor Town

River Inn of Harbor Town

4 out of 5
Mud Island
per person
Sep 21 - Sep 24
found 20 hours ago
Roundtrip flight included
New York (NYC) to Memphis (MEM)
9.6/10 Exceptional! (769 reviews)
Beautiful hotel and surrounding area. Staff were great. The food was delicious.

Reviewed on Jun 30, 2025

The Rambler

The Rambler

4 out of 5
Downtown Memphis
per person
Aug 14 - Aug 17
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Memphis (MEM)
9.2/10 Wonderful! (453 reviews)
Loved this property. So close to everything and street parking was pretty easy to find.

Reviewed on Jul 11, 2025

Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most. Learn more about South Main
Beale Street showing nightlife, night scenes and street scenes

Downtown Memphis

4 out of top 10 points of interest in this area
4/5(1,782 area reviews)

Home to the Memphis Redbirds and Grizzlies NBA team, this central business district offers entertainment, dining, and attractions like Beale Street, FedExForum, and AutoZone Park. Easily accessible via major highways and public transit options.

Find hotels in Downtown Memphis

South Main Hotel Deals

ARRIVE Memphis
ARRIVE Memphis
4 out of 5
477 S Main St, Memphis, TN
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $168 total per night from Jul 14 to Jul 15
$168 total
Jul 14 - Jul 15
Total includes taxes and fees
9.6/10 Exceptional! (1,008 reviews)
"The hotel was quaint and decorated in mid century. The staff was so accommodating and very nice. The have a restaurant in the hotel so it’s convenient if you want to grab coffee or a bite to eat. It’s a dog friendly hotel which is great if you want to bring your fur babies along. The rooms are comfortable. ..."

Reviewed on Jul 10, 2025

ARRIVE Memphis
The Central Station Memphis, Curio Collection by Hilton
The Central Station Memphis, Curio Collection by Hilton
4 out of 5
545 South Main, Memphis, TN
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $153 total per night from Jul 20 to Jul 21
$153 total
Jul 20 - Jul 21
Total includes taxes and fees
8.8/10 Excellent! (1,001 reviews)
Fun Themed Hotel
"We were in Memphis for two nights and enjoyed our stay at the Central Station. The hotel is beautiful with both music and train decor. It is an active Amtrak stop which is neat in itself. It is a bit of a walk to Beale from there we were able to manage it with kids. There is also a ton of great restaurants ..."

Reviewed on Jul 2, 2025

The Central Station Memphis, Curio Collection by Hilton
The Rambler
The Rambler
4 out of 5
400 S Main St, Memphis, TN
Fully refundableReserve now, pay when you stay
$130 nightly
The price is $154 total per night from Jul 27 to Jul 28
$154 total
Jul 27 - Jul 28
Total includes taxes and fees
9/10 Wonderful! (459 reviews)
"Loved this property. So close to everything and street parking was pretty easy to find."

Reviewed on Jul 11, 2025

The Rambler
See all 1,543 properties in South Main
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

All Inclusive Vacations

All Inclusive Vacations

Beach Vacations

Beach Vacations

Kid Friendly Vacations

Kid Friendly Vacations

Discover the most popular places to visit in South Main

Graceland showing a house and a pool

Graceland

4.5/5(1,408 reviews)

Step into the lavish mansion where Elvis relaxed, entertained guests and recorded music for a fascinating glimpse into his private life and career.

Graceland
Beale Street which includes nightlife, street scenes and a city

Beale Street

4/5(1,985 reviews)

With iconic landmarks, historic buildings and live music venues, Beale Street, "the Home of the Blues" is Memphis as it was at the turn of the 20th century.

Beale Street
University of Memphis

University of Memphis

4/5(391 reviews)

Explore the campus of University of Memphis during your stay in Memphis. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.

University of Memphis

Things to do

A Self Guided Walking Tour of Brews, Blues and BBQ in Memphis

A Self Guided Walking Tour of Brews, Blues and BBQ in Memphis

$12
per adult
A Self Guided Walking Tour of Brews, Blues and BBQ in Memphis
Downtown Memphis: History and Must-See Sites with Self-Guided Audio Tour

Downtown Memphis: History and Must-See Sites with Self-Guided Audio Tour

$10
per traveler
Downtown Memphis: History and Must-See Sites with Self-Guided Audio Tour
Memphis: Haunted Memphis Bus Tour

Memphis: Haunted Memphis Bus Tour

$33
per adult
Memphis: Haunted Memphis Bus Tour
See all activities in Memphis
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.