South Main Vacations from $359
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Your South Main Vacation
Book your vacation package to South Main and get ready to explore its nightlife and plenty more. Whether you're looking for adventure or relaxation, you'll discover it in this sought-after neighborhood. Can't wait to head out and see the sights during your trip to South Main? Don't miss nearby attractions like Orpheum Theatre, Sun Studio and Stax Museum of American Soul Music. Expedia will help you turn your dream South Main vacation into reality, whatever your travel plans or budget.
The Latest South Main Vacation Packages
The Stallion
Reviewed on Dec 8, 2025
Hampton Inn & Suites Memphis-Beale Street
Reviewed on Dec 10, 2025
Where to stay in South Main
Downtown Memphis
Home to the Memphis Redbirds and Grizzlies NBA team, this central business district offers entertainment, dining, and attractions like Beale Street, FedExForum, and AutoZone Park. Easily accessible via major highways and public transit options.
South Main Hotel Deals
The Central Station Memphis, Curio Collection by Hilton
STAFF was helpful, cheerful and knowledgeable about the facilities and town. Made for a delightful visit. Kudos to Ron at check in. His supervisory position was well deserved.
Reviewed on Dec 7, 2025
ARRIVE Memphis
The whole vibe was amazing! From the lobby, to the staff, to the room, and the valet, everything was incredible. The hotel is situated within walking distance of Beale St. We would definitely stay here again.
Reviewed on Dec 9, 2025
The Rambler
OMG this place was a dream! Already looking to book again with friends and family. Clean, spacious, and very secure. We booked the penthouse with 6br/5ba and had more than enough space for all of us with two large living areas. Noise from other guest wasn’t an issue and we parked right outside the ...
Reviewed on Dec 2, 2025
Discover the most popular places to visit in South Main
Graceland
Step into the lavish mansion where Elvis relaxed, entertained guests and recorded music for a fascinating glimpse into his private life and career.
Beale Street
With iconic landmarks, historic buildings and live music venues, Beale Street, "the Home of the Blues" is Memphis as it was at the turn of the 20th century.
University of Memphis
Explore the campus of University of Memphis during your stay in Memphis. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.
Things to do
Mobsters, Mayhem, & Murder of Memphis Ghost Tour
