South Main Vacations from $245

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Your South Main Vacation

Book your vacation package to South Main and get ready to explore its nightlife and plenty more. Whether you're looking for adventure or relaxation, you'll discover it in this sought-after neighborhood. Can't wait to head out and see the sights during your trip to South Main? Don't miss nearby attractions like Orpheum Theatre, Sun Studio and Stax Museum of American Soul Music. Expedia will help you turn your dream South Main vacation into reality, whatever your travel plans or budget.

The Latest South Main Vacation Packages

Price found within the past 48 hours. Click for updated prices.
OYO Hotel Memphis TN I-40

OYO Hotel Memphis TN I-40

2.5 out of 5
Price was $325, price is now $245 per person
$245
per person
Jan 26 - Jan 30
found 11 hours ago
Roundtrip non-stop flight included
New York (NYC) to Memphis (MEM)
8.4/10 Very Good! (1,002 reviews)
Lovely ambiance around the reception brought a positive feeling. The room maintained a fresh look with clean surfaces. Lighting contributed to a cozy environment. Service quality met expectations well.

Reviewed on Nov 22, 2025

River Inn of Harbor Town

River Inn of Harbor Town

4 out of 5
Mud Island
Price was $823, price is now $596 per person
$596
per person
Jan 16 - Jan 18
found 1 day ago
Roundtrip non-stop flight included
Charlotte (CLT) to Memphis (MEM)
19.2/10 Exceptional! (783 reviews)
Very nice clean, quiet property. Breakfast was great.

Reviewed on Oct 18, 2025

The Westin Memphis Beale Street

The Westin Memphis Beale Street

4 out of 5
Downtown Memphis
Price was $711, price is now $540 per person
$540
per person
Jan 16 - Jan 19
found 2 days ago
Roundtrip non-stop flight included
Charlotte (CLT) to Memphis (MEM)
17.2/10 Exceptional! (1,005 reviews)
Very clean and perfect location

Reviewed on Nov 16, 2025

Hu. Hotel

Hu. Hotel

3.5 out of 5
Downtown Memphis
Price was $647, price is now $501 per person
$501
per person
Jan 16 - Jan 19
found 2 days ago
Roundtrip non-stop flight included
Charlotte (CLT) to Memphis (MEM)
16.8/10 Exceptional! (1,556 reviews)
Deadrick was amazing, he made the stay worth it. Carpet in room was a lil out dated and the the breakfast could have changed. Maybe switch to bacon some days. But Deadrick made the stay worth the lil things, so attentive to the guess and always had a smile on his face. The clerk that wore the orange glasses was great also. Sorry couldn't remember her name, but she was great also. The roof top view was amazing at night. Very convenient to everything. Will book here again. (if Deadrick still work there lol)

Reviewed on Nov 22, 2025

The Stallion

The Stallion

4 out of 5
Downtown Memphis
Price was $729, price is now $571 per person
$571
per person
Jan 16 - Jan 19
found 2 days ago
Roundtrip non-stop flight included
Charlotte (CLT) to Memphis (MEM)
19.6/10 Exceptional! (149 reviews)
Really pleasant stay. Plenty of secure parking in the basement, and the accommodation was clean and well presented. We were impressed with the communication from the host. Highly recommend.

Reviewed on Nov 22, 2025

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Where to stay in South Main

Find the best South Main areas and neighborhoods for the activities you enjoy most. Learn more about South Main
Beale Street showing nightlife, night scenes and street scenes

Downtown Memphis

3 out of top 10 points of interest in this area
4/5(1,782 area reviews)

Home to the Memphis Redbirds and Grizzlies NBA team, this central business district offers entertainment, dining, and attractions like Beale Street, FedExForum, and AutoZone Park. Easily accessible via major highways and public transit options.

Find hotels in Downtown Memphis
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in South Main

Graceland showing a house and a pool

Graceland

Step into the lavish mansion where Elvis relaxed, entertained guests and recorded music for a fascinating glimpse into his private life and career.

Graceland
Beale Street which includes nightlife, street scenes and a city

Beale Street

With iconic landmarks, historic buildings and live music venues, Beale Street, "the Home of the Blues" is Memphis as it was at the turn of the 20th century.

Beale Street
University of Memphis

University of Memphis

Explore the campus of University of Memphis during your stay in Memphis. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.

University of Memphis

Things to do

Come to be told the true crime history of these haunted stops.

Mobsters, Mayhem, & Murder of Memphis Ghost Tour

$26
per adult
Mobsters, Mayhem, & Murder of Memphis Ghost Tour
Memphis: City Discovery Bus Tour

Memphis: City Discovery Bus Tour

$38
per adult
98% of travellers recommend
Memphis: City Discovery Bus Tour
Memphis Discovery Tour

Memphis Discovery Tour

$38
per adult
96% of travellers recommend
Memphis Discovery Tour
See all activities in Memphis
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