
South Main Vacations from $245
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Your South Main Vacation
Book your vacation package to South Main and get ready to explore its nightlife and plenty more. Whether you're looking for adventure or relaxation, you'll discover it in this sought-after neighborhood. Can't wait to head out and see the sights during your trip to South Main? Don't miss nearby attractions like Orpheum Theatre, Sun Studio and Stax Museum of American Soul Music. Expedia will help you turn your dream South Main vacation into reality, whatever your travel plans or budget.
The Latest South Main Vacation Packages

OYO Hotel Memphis TN I-40
Reviewed on Nov 22, 2025

River Inn of Harbor Town
Reviewed on Oct 18, 2025


Hu. Hotel
Reviewed on Nov 22, 2025

The Stallion
Reviewed on Nov 22, 2025
Where to stay in South Main

Downtown Memphis
Home to the Memphis Redbirds and Grizzlies NBA team, this central business district offers entertainment, dining, and attractions like Beale Street, FedExForum, and AutoZone Park. Easily accessible via major highways and public transit options.
Discover the most popular places to visit in South Main

Graceland
Step into the lavish mansion where Elvis relaxed, entertained guests and recorded music for a fascinating glimpse into his private life and career.

Beale Street
With iconic landmarks, historic buildings and live music venues, Beale Street, "the Home of the Blues" is Memphis as it was at the turn of the 20th century.

University of Memphis
Explore the campus of University of Memphis during your stay in Memphis. Make time to visit the area's shops, or simply enjoy its top-notch restaurants.
Things to do

Mobsters, Mayhem, & Murder of Memphis Ghost Tour

























