Title: South Roxana Vacation Packages 2026 from $573 | Expedia.com [South Roxana Travel Guide](https://expedia.com/South-Roxana.dx553248634983470823)[Hotels in South Roxana](https://expedia.com/South-Roxana-Hotels.d553248634983470823.Travel-Guide-Hotels)[Vacation Rentals in South Roxana](https://expedia.com/South-Roxana-Vacation-Rentals.d553248634983470823.Travel-Guide-VacationRentals)[Car Rentals in South Roxana](https://expedia.com/Car-Rentals-In-South-Roxana.d553248634983470823.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # South Roxana Vacations from $573 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your South Roxana Vacation Come and experience this wonderful city for yourself with a South Roxana vacation package. Think about staying in the neighborhood of Old Jamestown, which is great for nature and walking, and your time here is sure to be unforgettable. Make your trip to South Roxana even more fun by including some sightseeing. [Edwardsville Arts Center](https://www.expedia.com/Edwardsville-Arts-Center-St-Louis.d553248621532655948.Vacation-Attraction), [Lewis and Clark Interpretive Center](https://www.expedia.com/Lewis-And-Clark-Interpretive-Center-St-Louis.d6285389.Vacation-Attraction) and [National Great Rivers Museum](https://www.expedia.com/National-Great-Rivers-Museum-Alton.d6142452.Vacation-Attraction) are among the major attractions you'll want to explore. Your South Roxana vacation is clicks away. Search accommodations, flights and more on Expedia for a trip that's tailored just for you. ## The Latest South Roxana vacation packages Price found within the past 48 hours. Click for updated prices. ![ White House at Grand Central](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/f3c125ad_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### White House at Grand Central Grand Center $573 per person Jun 16 - Jun 20 found 1 day ago Roundtrip flight included Los Angeles (LAX) to St. Louis (STL) 8.4/10 Very Good! (129 reviews) Very clean and very friendly people Reviewed on Nov 11, 2025 ![Ameristar Casino Resort and Spa](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/70b128db_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Ameristar Casino Resort and Spa $719 per person Jun 16 - Jun 20 found 1 day ago Roundtrip flight included Los Angeles (LAX) to St. Louis (STL) 8.4/10 Very Good! (1,000 reviews) Overall it was a positive experience but we were VERY disappointed when we found out our daughter couldn’t swim all weekend. We would not have booked it if we had known that. Reviewed on Mar 22, 2026 ![Angad Arts Hotel St. Louis, Tapestry Collection by Hilton](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton Grand Center $624 per person Jun 16 - Jun 20 found 1 day ago Roundtrip flight included Los Angeles (LAX) to St. Louis (STL) 8.8/10 Excellent! (1,065 reviews) Cleaning needs help in the rooms and bathrooms. Room 511 hopefully is the smallest of all the rooms. You couldn’t use the chair fully with the desk and had to take turns in areas it was so tight. The staff was wrong about times for the Terrance bar and restaurant causing us to wait for that and then miss the downstairs restaurant being open so we waited a few more hours to find a place to eat. Simple mistake but that’s their job. Reviewed on Mar 22, 2026 ![Home2 Suites by Hilton St. Louis Downtown](https://images.trvl-media.com/lodging/77000000/76520000/76510800/76510729/104b5741_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Home2 Suites by Hilton St. Louis Downtown Downtown West $672 per person Apr 27 - Apr 30 found 11 hours ago Roundtrip non-stop flight included Los Angeles (LAX) to St. Louis (STL) 8/10 Very Good! (696 reviews) Very convenient to Enterprise Arena. Only complaint is valet parking (which is necessary because no on street or other options) is expensive. Reviewed on Mar 22, 2026 ![21C Museum Hotel St Louis ](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bd7064dc_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### 21C Museum Hotel St Louis Downtown West $589 per person Jun 16 - Jun 20 found 1 day ago Roundtrip flight included Los Angeles (LAX) to St. Louis (STL) 9/10 Wonderful! (1,647 reviews) Just a beautiful hotel. It is our 3rd time visiting. And will keep going back. The valet parking is a lot too expensive. I should have asked. But what is one gonna do. My bad. Reviewed on Mar 23, 2026 Don't see what you're looking for? See all available trips from Columbus to South Roxana [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-24/2026-05-01/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=STL&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ### Discover the most popular places to visit in South Roxana #### CP Pinball Enjoy an outing to CP Pinball during your stay in South Roxana. You can attend a sporting event while in the area. [](https://expedia.com/CP-Pinball-South-Roxana.d553248621532648632.Vacation-Attraction) ## South Roxana Hotel Deals ![Drury Plaza Hotel St. Louis at the Arch](https://images.trvl-media.com/lodging/1000000/550000/546300/546271/e43b9580_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Plaza Hotel St. Louis at the Arch 2 South 4th Street St. Louis MO Fully refundableReserve now, pay when you stay $162 nightly $189 total Mar 29 - Mar 30 Total with taxes and fees 9.4/10 Exceptional! (3,358 reviews) Every was great. Reviewed on Mar 24, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F29%2F2026&endDate=3%2F30%2F2026&selected=546271&PinnedHotelID=546271&HadPinnedHotel=true®ionId=553248634983470823) ![Pear Tree Inn St. Louis Near Union Station](https://images.trvl-media.com/lodging/1000000/30000/26600/26572/3056142b_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Pear Tree Inn St. Louis Near Union Station 2211 Market Street St. Louis MO $106 nightly $124 total Apr 5 - Apr 6 Total with taxes and fees 8.8/10 Excellent! (1,886 reviews) Great location overlooking Energizer stadium. Easy walk to Market Square. Loved the free breakfast and happy hour drink. Reviewed on Mar 24, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=26572&PinnedHotelID=26572&HadPinnedHotel=true®ionId=553248634983470823) ![Clayton Plaza Hotel & Extended Stay](https://images.trvl-media.com/lodging/1000000/20000/18200/18144/5c61cbf8_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Clayton Plaza Hotel & Extended Stay 7750 Carondelet Avenue St. Louis MO Fully refundableReserve now, pay when you stay $94 nightly $110 total Apr 19 - Apr 20 Total with taxes and fees 8.8/10 Excellent! (3,129 reviews) Stay was wonderful. Would definitely recommend. Reviewed on Mar 23, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F19%2F2026&endDate=4%2F20%2F2026&selected=18144&PinnedHotelID=18144&HadPinnedHotel=true®ionId=553248634983470823) [See all 1,490 properties in South Roxana](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F25%2F2026&endDate=3%2F26%2F2026®ionId=553248634983470823) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best South Roxana Vacation Packages ## South Roxana Essential Information | Language | English | | --------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ | | Currency | U.S dollars | | Closest Airport | Lambert-St. Louis Intl. Airport (STL) | | Population | 2,000 | | Top Sights | [Splash City Family Waterpark](https://www.expedia.com/Splash-City-Family-Waterpark-Collinsville.d6211797.Vacation-Attraction), [National Great Rivers Museum](https://www.expedia.com/National-Great-Rivers-Museum-Alton.d6142452.Vacation-Attraction) and [Gateway Fun Park](https://www.expedia.com/Gateway-Fun-Park-Collinsville.d6142388.Vacation-Attraction) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) 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it cheaper to book a South Roxana vacation as a package? ### When to book a vacation package to South Roxana? ### Does Expedia offer Book Now, Pay Later South Roxana vacation packages? \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app