
South Roxana Vacations from $191
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Your South Roxana Vacation
Come and experience this wonderful city for yourself with a South Roxana vacation package. Think about staying in the neighborhood of Old Jamestown, which is great for nature and walking, and your time here is sure to be unforgettable. Make your trip to South Roxana even more fun by including some sightseeing. Edwardsville Arts Center, Lewis and Clark Interpretive Center and National Great Rivers Museum are among the major attractions you'll want to explore. Your South Roxana vacation is clicks away. Search accommodations, flights and more on Expedia for a trip that's tailored just for you.
The Latest South Roxana vacation packages

DoubleTree by Hilton Hotel St. Louis - Chesterfield
Reviewed on May 4, 2026


Hilton Garden Inn Chesterfield
Reviewed on May 4, 2026

Home2 Suites by Hilton St. Louis Downtown
Reviewed on May 7, 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Reviewed on May 4, 2026
Discover the most popular places to visit in South Roxana
CP Pinball
Enjoy an outing to CP Pinball during your stay in South Roxana. You can attend a sporting event while in the area.
South Roxana Hotel Deals

Hyatt Regency St. Louis at The Arch
Very clean
Reviewed on May 8, 2026

Clayton Plaza Hotel & Extended Stay
Wonderful hot breakfast! Very clean room. Friendly, attentive staff! Great price for what you get. Would stay there again.
Reviewed on May 8, 2026

21C Museum Hotel St Louis
Really cool hotel with great onsite bar/restaurant, gym, pool and art gallery.
Reviewed on May 6, 2026
Find the Best South Roxana Vacation Packages
South Roxana Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lambert-St. Louis Intl. Airport (STL) |
Population | 2,000 |
Top Sights | Splash City Family Waterpark, National Great Rivers Museum and Gateway Fun Park |



















