South Roxana Vacations from $277

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Your South Roxana Vacation

Come and experience this wonderful city for yourself with a South Roxana vacation package. Think about staying in the neighborhood of Old Jamestown, which is great for nature and walking, and your time here is sure to be unforgettable. Make your trip to South Roxana even more fun by including some sightseeing. Edwardsville Arts Center, Lewis and Clark Interpretive Center and National Great Rivers Museum are among the major attractions you'll want to explore. Your South Roxana vacation is clicks away. Search accommodations, flights and more on Expedia for a trip that's tailored just for you.

The Latest South Roxana vacation packages

Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Chesterfield

Hilton Garden Inn Chesterfield

3 out of 5
Save 100% on your flight
Price was $378, price is now $277 per person
$277
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.2/10 Very Good! (779 reviews)
Staff was informative during check-in. Room was clean and the TV even had WELCOME with my name on it. Would stay here again.

Reviewed on Dec 22, 2025

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was $712, price is now $353 per person
$353
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
9.2/10 Wonderful! (1,600 reviews)
Clean room and easy parking.

Reviewed on Feb 2, 2026

The Cheshire

The Cheshire

4 out of 5
Save 100% on your flight
Price was $495, price is now $362 per person
$362
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.6/10 Excellent! (1,002 reviews)
The Cheshire is in a class by itself. The halls and sitting areas are so full of history and there’s an ambiance that we just love. Our suite, Treasure Island, was amazing! Large, clean, luxurious and cozy with a beautiful fireplace and large jacuzzi. We had a delicious dinner at the Basso, relaxed in the very British, cozy Fox & Hound, enjoyed a coffee at the Tudor styled Starbucks and as always, enjoyed breakfast beside the fireplace. We loved our stay!

Reviewed on Jan 28, 2026

Hotel Saint Louis, Autograph Collection

Hotel Saint Louis, Autograph Collection

4 out of 5
Downtown St. Louis
Save 100% on your flight
Price was $573, price is now $420 per person
$420
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.8/10 Excellent! (458 reviews)
Property and room was really nice. I will be staying here in the future

Reviewed on Nov 25, 2025

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Save 100% on your flight
Price was $534, price is now $393 per person
$393
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to St. Louis (STL)
8.4/10 Very Good! (1,006 reviews)
The room was great. I enjoyed my stay.

Reviewed on Feb 3, 2026

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Discover the most popular places to visit in South Roxana

CP Pinball

Enjoy an outing to CP Pinball during your stay in South Roxana. You can attend a sporting event while in the area.

CP Pinball

South Roxana Hotel Deals

21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $162 total per night from Feb 22 to Feb 23
$162 total
Feb 22 - Feb 23
Total with taxes and fees
9/10 Wonderful! (1,594 reviews)
Everything was great i can’t wait to stay again

Reviewed on Feb 6, 2026

21C Museum Hotel St Louis
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $112 total per night from Feb 8 to Feb 9
$112 total
Feb 8 - Feb 9
Total with taxes and fees
8.8/10 Excellent! (3,081 reviews)
Lovely hotel. Great breakfast

Reviewed on Jan 29, 2026

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundableReserve now, pay when you stay
$129 nightly
The price is $152 total per night from Feb 28 to Mar 1
$152 total
Feb 28 - Mar 1
Total with taxes and fees
8.4/10 Very Good! (4,017 reviews)
Nice room & friendly staff!

Reviewed on Jan 28, 2026

Hyatt Regency St. Louis at The Arch
See all 1,452 properties in South Roxana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best South Roxana Vacation Packages

South Roxana Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Lambert-St. Louis Intl. Airport (STL)
Population
2,000
Top Sights
Splash City Family Waterpark, National Great Rivers Museum and Gateway Fun Park

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Frequently asked questions

How much does a South Roxana vacation package cost?
You can grab a vacation package to this popular destination from $277 on Expedia. However, how much your vacation to South Roxana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to South Roxana?
If you're looking to book a cheap South Roxana vacation package, consider visiting in December, January and February. You'll usually find lower rates on accommodations and flights during these quieter months — ideal for travelers wishing to save money.
How many days is enough for South Roxana?
With a well-organized travel plan, you can easily visit the main South Roxana sights in a handful of days. But if you'd like to discover hidden spots or go on day trips, consider booking your South Roxana vacation for longer.
How to find the best South Roxana package deals?
Use Expedia's filter tool to find some tempting South Roxana package deals. When you start your search, just set your maximum budget and then order the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or browse for South Roxana package deals in the off-peak season. Switch up your travel dates and you may score even better discounts. As a rule of thumb, it's usually best to book your vacation package well in advance.
Is it cheaper to book a South Roxana vacation as a package?
An Expedia vacation package could land you significant savings when compared to arranging flights and accommodations separately. Better still, you can customize your South Roxana trip to match your exact style. Pick your preferred flight time, select the hotel type and add a car rental. Browse our bundle deals and find out how much you can save.
When to book a vacation package to South Roxana?
If you've got your South Roxana travel dates finalized, book as soon as you can to score some terrific deals. With Expedia, you can typically reserve some flights up to a year in advance. Prefer spontaneous adventures? Our last-minute deals are ideal for setting off on a whim.
Does Expedia offer Book Now, Pay Later South Roxana vacation packages?
Set off on your perfect escape to South Roxana with help from Expedia's Book Now, Pay Later vacations. There's no need to scrimp and save or wait until the next payday — we've teamed up with online lender Affirm to give you more flexibility with your finances. Our vacation packages with payment plans mean you can spread the total cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's a breeze to budget for your trip and snap up bargains before they sell out.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.