Southern Indiana Vacations from $571

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Your Southern Indiana Vacation

Make planning your next big adventure a breeze with a Southern Indiana vacation package. Whether it's nature, history or something else that draws you here, our packages will help you discover it all. A trip to Southern Indiana wouldn't be complete without exploring some of its leading cities, starting with Louisville. A couple of the most popular attractions here include KFC Yum Center and Kentucky Kingdom. Evansville is another favorite with Southern Indiana travelers. Visitors to this destination enjoy Ford Center and Bally's Evansville Casino. When you're ready to stop daydreaming and start doing, Expedia will help turn your Southern Indiana vacation into a reality.

The Latest Southern Indiana vacation packages

Price found within the past 48 hours. Click for updated prices.
Caesars Southern Indiana
Galt House Hotel Trademark Collection by Wyndham
Hyatt Regency Louisville
Microtel Inn by Wyndham Louisville East
Super 8 by Wyndham Louisville/Expo Center
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Where to stay in Southern Indiana

Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana

Discover the most popular places to visit in Southern Indiana

What to do in Southern Indiana

Southern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive, Clarksville, IN
Fully refundable
$67 nightly
The price is $76 total per night from Jul 22 to Jul 23
$76 total
Jul 22 - Jul 23
Total includes taxes and fees
6.8/10 (2,211 reviews)
"Staff is accommodating and nice. Hotel is not the cleanest and could definitely use updates. There was some construction going on so maybe they were working on updates? Overall we had"

Reviewed on Jul 10, 2025

Radisson Hotel Louisville North
Hyatt Place Evansville

Hyatt Place Evansville

3 out of 5
202 Se 2nd St, Evansville, IN
Fully refundableReserve now, pay when you stay
$118 nightly
The price is $136 total per night from Jul 20 to Jul 21
$136 total
Jul 20 - Jul 21
Total includes taxes and fees
9.4/10 Exceptional! (1,004 reviews)
"Stayed 4th of July!"

Reviewed on Jul 12, 2025

Hyatt Place Evansville
Quality Inn & Suites

Quality Inn & Suites

2.5 out of 5
440 South Main St, Ferdinand, IN
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from Aug 4 to Aug 5
$110 total
Aug 4 - Aug 5
Total includes taxes and fees
7/10 Good! (574 reviews)
"Not enough staff working. Had to request additional breakfast items multiple times both days as trays were empty often. Leaky air conditioning never addressed."

Reviewed on Jul 13, 2025

Quality Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Southern Indiana Vacation Packages

Southern Indiana Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Cincinnati - Northern Kentucky Intl. Airport (CVG)

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.