Southern Indiana

Travel Guide

Kentucky Center for the Performing Arts featuring modern architecture
Belle of Louisville featuring a bay or harbor and a ferry as well as a small group of people
Louisville Slugger Museum showing interior views
Belle of Louisville showing a ferry and a bay or harbor as well as a small group of people
Frazier International History Museum which includes interior views
Hoosier traditions add a unique slant to your trip to the towns of this region, while the forest offers a serene spot for a picnic beside old buffalo grounds.

Visit Southern Indiana to discover a region with proud traditions and a varied topography. Its cities are known for the famous Hoosier culture, while Hoosier National Forest is among the leafy preserves that show off the area’s scenic hills and valleys. Travel through the southern part of this Midwestern state for insights into its exceptional culture and terrain.

Arrive in the largest city in the region, Evansville, for a sense of local culture. Bring the kids to the Mesker Park Zoo & Botanic Garden, before watching a game of baseball at Bosse Field. This is one of the oldest baseball arenas in the U.S., having been inaugurated in 1915. Check out the USS LST Ship Memorial docked along the Ohio River, taking a look around what is the last fully operational World War II Landing Ship in the country.

For less urban activities, explore Hoosier National Forest. Set out on trails meandering up and down the park’s hills or try horseback riding, fishing or camping.

Follow the Buffalo Trace route across the southern part of the state. Long before major settlements, buffalo and Native American people lived in these areas. Find information at the Falls of the Ohio State Park in Clarksville. Marengo Cave and Patoka Lake State Park offer other outdoor adventures.

Plan an eclectic family trip to French Lick, with casinos and spas for adults and the French Lick Scenic Railway for kids of any age. Purchase candy from one of the country’s oldest family-owned candy companies in Jeffersonville and visit an Amish village in Montgomery.

Southern Indiana is separated from Kentucky by the Ohio River. Arrive at Indianapolis International Airport and drive south for 165 miles (265 kilometers) to reach Evansville in less than 3 hours. Louisville, Kentucky, is just across the river. Explore the surroundings for nearby cities such as Cincinnati, Lexington and Nashville across state borders. The region has a distinctive Hoosier culture, as well as a varied and picturesque topography.

Where to stay in Southern Indiana

Louisville Science Center featuring outdoor art

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

West Main Historic District
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Downtown Evansville

Dive into the cultural hub of Evansville, where you can catch a performance by the Evansville Philharmonic Orchestra at Victory Theatre or explore the Children's Museum of Evansville. Don't miss the LST-325 Museum and Ford Center nearby!

Downtown Evansville
Cute Gastropub in downtown Louisville. The Burger had a pickled tomator on the bottom, I could have eaten a whole plate of those! #FoodieFinds

Portland

While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.

Portland
Whiteside Bakery built in 1908, later incorporated into the General Baking Co produced Bond Bread, a favorite of Hopalong Cassidy.

California

If you're spending some time in California, Ohio River Valley and Union Station are top sights worth seeing.

California
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Shawnee

Though Shawnee might not have many top sights, you can venture to the surrounding area to see attractions like Mansion Row Historic District and Frazier International History Museum.

Shawnee
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Russell

If you're spending some time in Russell, Ohio River Valley and I. Willis Cole Residence are top sights worth seeing.

Russell
Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
The price is $51 total per night from Nov 27 to Nov 28
$51 total
per night
Nov 27 - Nov 28
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
6.8/10 (2,533 reviews)
No i thought breakfast was free

Reviewed on Nov 17, 2025

Radisson Hotel Louisville North
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3 out of 5
4900 Water Tower Road Jeffersonville IN
The price is $84 total per night from Nov 28 to Nov 29
$84 total
per night
Nov 28 - Nov 29
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free parking, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
9.4/10 Exceptional! (382 reviews)
Very clean and quiet. We were short 1 set of towels as 4 guests. A free breakfast accommodation would be appreciated But great stay overall

Reviewed on Nov 17, 2025

Hilton Garden Inn Jeffersonville Louisville North
Comfort Inn & Suites Clarksville - Louisville North

Comfort Inn & Suites Clarksville - Louisville North

2.5 out of 5
1485 Broadway St Clarksville IN
The price is $111 total per night from Nov 29 to Nov 30
$111 total
per night
Nov 29 - Nov 30
Book a stay at this business-friendly hotel in Clarksville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,007 reviews)
The room was great. The parking leaves much to be desired.

Reviewed on Nov 19, 2025

Comfort Inn & Suites Clarksville - Louisville North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Villas at French Lick Springs

The Villas at French Lick Springs

3 out of 5
8718 W State Road 56 French Lick IN
Stay at this condo in French Lick. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (272 reviews)
Villa was clean, but outdated. It was very quiet with no noise from adjoining villas. Location is good and area excellent. Good value and would stop there again

Reviewed on Nov 18, 2025

The Villas at French Lick Springs
John's cabin

John's cabin

French Lick IN
Stay at this cabin in French Lick. Enjoy free WiFi, a garden, and an in-room coffeemaker. Popular attractions French Lick Springs Hotel and French Lick Casino ...
9.8/10 Exceptional! (59 reviews)
Had a fantastic overnight at John’s Cabin.

Reviewed on Oct 29, 2025

John's cabin
Two Furnished cabins minutes from Patoka Lake and French Lick. Book 1 or 2

Two Furnished cabins minutes from Patoka Lake and French Lick. Book 1 or 2

2 out of 5
Taswell IN
Stay at this cabin in Taswell. Enjoy free breakfast, a water park, and a garden.
10/10 Exceptional! (13 reviews)
The owners are amazing welcoming people. Made us feel at home! Everything was wonderful. We had a good time! We wil definitely bw going back!

Reviewed on Nov 9, 2025

Two Furnished cabins minutes from Patoka Lake and French Lick. Book 1 or 2
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Cities near Southern Indiana

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