Southern Indiana

Travel Guide

Kentucky Center for the Performing Arts featuring modern architecture
Belle of Louisville featuring a bay or harbor and a ferry as well as a small group of people
Louisville Slugger Museum showing interior views
Belle of Louisville showing a bay or harbor and a ferry as well as a small group of people
Frazier International History Museum which includes interior views
Hoosier traditions add a unique slant to your trip to the towns of this region, while the forest offers a serene spot for a picnic beside old buffalo grounds.

Visit Southern Indiana to discover a region with proud traditions and a varied topography. Its cities are known for the famous Hoosier culture, while Hoosier National Forest is among the leafy preserves that show off the area’s scenic hills and valleys. Travel through the southern part of this Midwestern state for insights into its exceptional culture and terrain.

Arrive in the largest city in the region, Evansville, for a sense of local culture. Bring the kids to the Mesker Park Zoo & Botanic Garden, before watching a game of baseball at Bosse Field. This is one of the oldest baseball arenas in the U.S., having been inaugurated in 1915. Check out the USS LST Ship Memorial docked along the Ohio River, taking a look around what is the last fully operational World War II Landing Ship in the country.

For less urban activities, explore Hoosier National Forest. Set out on trails meandering up and down the park’s hills or try horseback riding, fishing or camping.

Follow the Buffalo Trace route across the southern part of the state. Long before major settlements, buffalo and Native American people lived in these areas. Find information at the Falls of the Ohio State Park in Clarksville. Marengo Cave and Patoka Lake State Park offer other outdoor adventures.

Plan an eclectic family trip to French Lick, with casinos and spas for adults and the French Lick Scenic Railway for kids of any age. Purchase candy from one of the country’s oldest family-owned candy companies in Jeffersonville and visit an Amish village in Montgomery.

Southern Indiana is separated from Kentucky by the Ohio River. Arrive at Indianapolis International Airport and drive south for 165 miles (265 kilometers) to reach Evansville in less than 3 hours. Louisville, Kentucky, is just across the river. Explore the surroundings for nearby cities such as Cincinnati, Lexington and Nashville across state borders. The region has a distinctive Hoosier culture, as well as a varied and picturesque topography.

Where to stay in Southern Indiana

Louisville Science Center featuring outdoor art

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

West Main Historic District
Cloudy Summer Aerial of Evansville’s Historic Courthouse

Downtown Evansville

Dive into the cultural hub of Evansville, where you can catch a performance by the Evansville Philharmonic Orchestra at Victory Theatre or explore the Children's Museum of Evansville. Don't miss the LST-325 Museum and Ford Center nearby!

Downtown Evansville
The Sherman Minton Bridge is a double-deck through arch bridge spanning the Ohio River, carrying I-64 and US 150 over the river between Kentucky and Indiana. The bridge connects the west side of Louisville, Kentucky to downtown New Albany, Indiana.

Portland

While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.

Portland
Whiteside Bakery built in 1908, later incorporated into the General Baking Co produced Bond Bread, a favorite of Hopalong Cassidy.

California

If you're spending some time in California, Ohio River Valley and Union Station are top sights worth seeing.

California
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Russell

If you're spending some time in Russell, Ohio River Valley and I. Willis Cole Residence are top sights worth seeing.

Russell
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Downtown French Lick

While Downtown French Lick might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like French Lick Springs Hotel and French Lick Casino.

Downtown French Lick
Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
$59 nightly
The price is $67 total per night from Apr 21 to Apr 22
$67 total
Apr 21 - Apr 22
Total with taxes and fees
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
7/10 Good! (2,854 reviews)
I was double charged for the hotel room, as I paid through Expedia the hotel thought it would be nice of themselves to help themselves with my bank card and charge an extra $150 and put two separate $100 holds on my account in a $50 hold.

Reviewed on Mar 20, 2026

Radisson Hotel Louisville North
Fairfield Inn By Marriott Evansville East

Fairfield Inn By Marriott Evansville East

3 out of 5
7879 Eagle Crest Blvd Evansville IN
$84 nightly
The price is $97 total per night from Mar 29 to Mar 30
$97 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (474 reviews)
Great people when we visited and room was nice. Only concern was I contacted them over a matter after we left they just shrugged it off and acted like it was no big deal

Reviewed on Mar 20, 2026

Fairfield Inn By Marriott Evansville East
Derby Hotel & Suites

Derby Hotel & Suites

2 out of 5
505 K Marriot Dr Clarksville IN
$57 nightly
The price is $65 total per night from Mar 29 to Mar 30
$65 total
Mar 29 - Mar 30
Total with taxes and fees
Stay at this hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Louisville Slugger Museum and KFC Yum Center are located ...
5/10 (9 reviews)
Have someone on staff at hotel for assistance clean rooms better

Reviewed on Mar 20, 2026

Derby Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Villas at French Lick Springs

The Villas at French Lick Springs

3 out of 5
8718 W State Road 56 French Lick IN
Stay at this condo in French Lick. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (294 reviews)
Our family spring break here was near prefect. Liked villa and French Lick hotel pools. Clean condo. Well stocked for cooking, laundry and relaxing in jacuzzi. One night out at Chicago Pizza was great and happy with bowling at FL Hotel. Did not like the steep walk from parking area and unloading ...

Reviewed on Mar 20, 2026

The Villas at French Lick Springs
Charming totally updated 3-bedroom, 2 bathroom house full of character

Charming totally updated 3-bedroom, 2 bathroom house full of character

Evansville IN
Stay at this vacation home in Evansville. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions Ford Center and Moutoux Park are located ...
10/10 Exceptional! (1 review)
Comfortable, quiet, close to everything, and the host responds quickly to requests. I will be staying here again.

Reviewed on Mar 15, 2026

Charming totally updated 3-bedroom, 2 bathroom house full of character
Charming 4-bedroom house with WiFi and AC in French Lick with country setting

Charming 4-bedroom house with WiFi and AC in French Lick with country setting

French Lick IN
Book a stay at this golf vacation home in French Lick. Enjoy free WiFi, private pools, and a garden. Popular attractions Big Splash Adventure and French Lick ...
9.8/10 Exceptional! (26 reviews)
Our family had an amazing time at Crew Holler. Rodney was a great host who was extremely gracious. You could tell that a tremendous amount of thought and effort was poured into this property. Our two families have never stayed anywhere that had so many amenities. Every cabinet, pantry, and closet ...

Reviewed on Mar 19, 2026

Charming 4-bedroom house with WiFi and AC in French Lick with country setting
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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