
Southern Indiana Pet-friendly Vacations
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Top Pet-friendly vacation packages in Southern Indiana
Price found within the past 48 hours. Click for updated prices.

21c Museum Hotel Louisville
Downtown Louisville
$894
per person
Oct 8 - Oct 11
found 12 hours ago
Roundtrip flight included
Dallas (DFW) to Louisville (SDF)
9.4/10 Exceptional! (1,003 reviews)
This is meant to be the flagship 21C and it was at one time, but it has started to fray at the edges noticably.. having stayed at the Lexington location recently I was saddened by the fallen state of the flagship. Even the gift shop was ramshackle. The peguins have all faded.. the room decor was tatty.. what was the meaning of what looked to landuary netting stappled over the beds? It felt like some charity shop try hard highschool art project. The bathroom lights were gloomy.. its simply a sad state of affairs. and considering the boom of small chic hotels in nearby hipper locations .. the 21c Louisville needs to step back into what they started as and bring it. They were the first.. let it not be on its last leg
Reviewed on Aug 6, 2026


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View all trips3 Night Pet-friendly vacations in Southern Indiana
Price found within the past 48 hours. Click for updated prices.

21c Museum Hotel Louisville
Downtown Louisville
$894
per person
Oct 8 - Oct 11
found 12 hours ago
Roundtrip flight included
Dallas (DFW) to Louisville (SDF)
9.4/10 Exceptional! (1,003 reviews)
This is meant to be the flagship 21C and it was at one time, but it has started to fray at the edges noticably.. having stayed at the Lexington location recently I was saddened by the fallen state of the flagship. Even the gift shop was ramshackle. The peguins have all faded.. the room decor was tatty.. what was the meaning of what looked to landuary netting stappled over the beds? It felt like some charity shop try hard highschool art project. The bathroom lights were gloomy.. its simply a sad state of affairs. and considering the boom of small chic hotels in nearby hipper locations .. the 21c Louisville needs to step back into what they started as and bring it. They were the first.. let it not be on its last leg
Reviewed on Aug 6, 2026

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See all available trips from Columbus to Southern Indiana
View all trips4 Night Pet-friendly vacations in Southern Indiana
Price found within the past 48 hours. Click for updated prices.


Aloft by Marriott Louisville Downtown
Downtown Louisville
$978
per person
Sep 13 - Sep 17
found 7 hours ago
Roundtrip non-stop flight included
Charlotte (CLT) to Louisville (SDF)
9/10 Wonderful! (1,006 reviews)
I love this hotel. It's my preferred stay when in Louisville. The staff, the rooms the lobby bar. The place is great
Reviewed on Aug 6, 2026

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View all tripsTop Pet-friendly Southern Indiana Hotels

Galt House Hotel Trademark Collection by Wyndham
140 North Fourth Street Louisville KY
- 3 hours drive from Holiday World and Splashin' Safari
This pet-friendly, city-center hotel welcomes dogs for an additional fee. Nearby Riverfront Plaza Belvedere is a good place to stretch your legs if you need ...

Omni Louisville Hotel
400 S. 2nd Street Louisville KY
- 3 hours drive from Holiday World and Splashin' Safari
Dogs and cats are welcome (fees apply) and can enjoy pet-friendly amenities, like food and water bowls, at this city-center hotel. Take a stroll at Riverfront ...

Holiday Inn Louisville Downtown by IHG
101 W. Muhammad Ali Blvd Louisville KY
- 3 hours drive from Holiday World and Splashin' Safari
Your four-legged friend can come along to this pet-friendly hotel (fees apply for pets). If you need a walk, try nearby Louisville Waterfront Park.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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