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Check availability on Southern Indiana 4 Star Hotels

Tonight
Aug 31 - Sep 1
Tomorrow
Sep 1 - Sep 2
This weekend
Sep 4 - Sep 6
Next weekend
Sep 11 - Sep 13

Our top choices for Southern Indiana 4-star hotels

Dining
Room
Front of property - evening/night
Dining

1. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville
United States
Jacob
$156 nightly
$183 total
Sep 10 - Sep 11
Total with taxes and fees
Galt House Hotel Trademark Collection by Wyndham
Lobby lounge
Exterior detail
Interior detail
Pool

2. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville
United States
Kara
$199 nightly
$234 total
Sep 2 - Sep 3
Total with taxes and fees
Omni Louisville Hotel
Lobby
Lobby
Exterior
Suite (VIP)

3. Hyatt Regency Louisville

Hyatt Regency Louisville
Downtown Louisville
United States
Arnetta
$127 nightly
$150 total
Sep 3 - Sep 4
Total with taxes and fees
Hyatt Regency Louisville
Lobby
Interior
Lobby
Bar (on property)

4. The Brown Hotel

The Brown Hotel
Downtown Louisville
United States
Rachel
$176 nightly
$208 total
Sep 1 - Sep 2
Total with taxes and fees
The Brown Hotel
Reception
Suite, 1 King Bed, Non Smoking, Corner | Living area
Restaurant
Pool

5. Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
Downtown Louisville
United States
Spencer
$130 nightly
$153 total
Sep 7 - Sep 8
Total with taxes and fees
Embassy Suites Louisville Downtown
Front of property
Room (Asleep in the Cyclone)
Fountain
Room (Asleep in the Cyclone)

6. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville
United States
Candice
$183 nightly
$216 total
Sep 3 - Sep 4
Total with taxes and fees
21c Museum Hotel Louisville
Bar (on property)
Coffee shop
Room
Coffee shop

7. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
Downtown Louisville
United States
Rebekah
$135 nightly
$159 total
Sep 7 - Sep 8
Total with taxes and fees
Hotel Genevieve part of JdV by Hyatt
Lobby
Exterior
Deluxe Single Room, 1 King Bed, City View
Lobby

8. The Grady

The Grady
Downtown Louisville
United States
Garrett
$208 nightly
$244 total
Sep 6 - Sep 7
Total with taxes and fees
The Grady
Exterior
Restaurant
Reception
Lobby

9. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville
United States
Lisa
$169 nightly
$199 total
Sep 5 - Sep 6
Total with taxes and fees
Louisville Marriott Downtown
Terrace/patio
Living room
Terrace/patio
Exterior

10. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville
United States
Jasmine
$195 nightly
$229 total
Sep 6 - Sep 7
Total with taxes and fees
Hotel Distil, Autograph Collection
Terrace/patio
Reception
Lobby
Exterior

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville
United States
Breeana
$171 nightly
$202 total
Sep 7 - Sep 8
Total with taxes and fees
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Lobby
View from room
Point of interest
Terrace/patio

12. DoubleTree by Hilton Evansville

DoubleTree by Hilton Evansville
Downtown Evansville
United States
Jennifer
$98 nightly
$112 total
Sep 13 - Sep 14
Total with taxes and fees
DoubleTree by Hilton Evansville
Exterior
Deluxe Suite, 1 Queen Bed, Non Smoking | Living area
Breakfast buffet
Lobby

13. Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
Downtown Louisville
United States
Jennifer
$152 nightly
$179 total
Sep 6 - Sep 7
Total with taxes and fees
Seelbach Hilton Louisville Downtown
Property entrance
Reception
Interior entrance
Dining

14. The Pepin Mansion Historic B&B

The Pepin Mansion Historic B&B
New Albany
United States
Ronald
$89 nightly
$101 total
Sep 1 - Sep 2
Total with taxes and fees
The Pepin Mansion Historic B&B
Lounge
Basic Suite, 1 King Bed, Non Smoking
Lounge
Point of interest

15. Stellar Suites

Stellar Suites
Downtown Louisville
United States
Brad
$156 nightly
$181 total
Sep 2 - Sep 3
Total with taxes and fees
Stellar Suites
Pool
Gym
Apartment, 3 Bedrooms, Non Smoking | 2 Units | Dining room
Exterior

16. CozySuites at Nulu

CozySuites at Nulu
Downtown Louisville
United States
Roy
$175 nightly
$203 total
Sep 3 - Sep 4
Total with taxes and fees
CozySuites at Nulu
Exterior
Terrace/patio
Interior
Private kitchen

17. stayAPT Suites Louisville North-Clarksville

stayAPT Suites Louisville North-Clarksville
Clarksville
United States
Chauntel
stayAPT Suites Louisville North-Clarksville
Living area
Living area
Living area
Exterior

18. The Reserve on Main

The Reserve on Main
Downtown Louisville
United States
De'Carlon
The Reserve on Main
Exterior
Point of interest
Breakfast area
Interior detail

19. Bourbon Barrel Inn Bed & Breakfast

Bourbon Barrel Inn Bed & Breakfast
Old Louisville
United States
jonathan
Bourbon Barrel Inn Bed & Breakfast
Family House, Multiple Beds | Private kitchen
Private kitchen
Family House, Multiple Beds | Living area
Front of property

20. Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
Sellersburg
United States
Tammy
Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb
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Learn more about Southern Indiana

Hoosier traditions add a unique slant to your trip to the towns of this region, while the forest offers a serene spot for a picnic beside old buffalo grounds.

See all hotels in Southern Indiana
A riverboat with multiple decks and passengers, docked near a bridge.

Top Southern Indiana Hotel Reviews

Find out more about Southern Indiana

Southern Indiana Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Southern Indiana, United States of America are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Southern Indiana 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Southern Indiana. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Southern Indiana, United States of America, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Southern Indiana hotels offer everything your heart desires.

Frequently asked questions

What are the best 4-star hotels in Southern Indiana?
If your Southern Indiana vacation leads you to Louisville, consider Galt House Hotel Trademark Collection by Wyndham. With lots of amenities such as massage services and a swimming pool, it scores top marks from many Expedia customers. Another popular pick here is Hyatt Regency Louisville. It also has 4 stars and offers designer toiletries and a swimming pool.
How much does it cost to stay in a 4-star hotel in Southern Indiana?
To book a 4-star hotel in Southern Indiana that's within your budget, use Expedia's handy filter tool. Browse the availability during your chosen dates and use our pricing filter to set your limit. You can also sort your results by the cheapest option first.
  • Search for the lowest price from $101
What's the difference between 5-star and 4-star hotels in Southern Indiana?
Offering an inviting traveler experience and upscale décor, 4-star hotels are an excellent option for your Southern Indiana break. These kinds of accommodations generally feature loads of handy amenities that make it easy to unpack and recharge — think pillowtop mattresses, restaurants and pools. Or live in the lap of luxury at a 5-star hotel designed to spoil you with exclusive perks and amenities. 24-hour front desk, oversized bathrooms and gourmet dining are typically featured at these swanky properties.

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