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Find Adults Only Resorts & Hotels in Southwest, MS from $90

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Check availability on Southwest Adults Only Resorts & Hotels

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Dec 5 - Dec 6
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Dec 6 - Dec 7
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Dec 5 - Dec 7
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Dec 12 - Dec 14

Top Southwest Adults Only Resorts & Hotels

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WaterView Casino & Hotel, Trademark Collection by Wyndham

WaterView Casino & Hotel, Trademark Collection by Wyndham

3.5 star property
Vicksburg
8.0 out of 10, Very Good, (1000)
"Great place"
United States
Sue
$82 nightly
The price is $90
Dec 7 - Dec 8
Total with taxes and fees
WaterView Casino & Hotel, Trademark Collection by Wyndham
Exterior detail
Stone House Musical B&B

Stone House Musical B&B

3.5 star property
Natchez
9.8 out of 10, Exceptional, (29)
"Mr. Joe was a delight. I was in the area for a friend’s doctoral celebration and decided to book. I’m glad I did. I enjoyed the hospitality and conversations. "
United States
Samuel D
$164 nightly
The price is $182
Dec 6 - Dec 7
Total with taxes and fees
Stone House Musical B&B
Front of property
Riverboat Bed & Breakfast

Riverboat Bed & Breakfast

3.0 star property
Natchez
9.8 out of 10, Exceptional, (17)
"Awesome place"
United States
Christopher
$205 nightly
The price is $228
Jan 1 - Jan 2, 2026
Total with taxes and fees
Riverboat Bed & Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Find out more about Southwest

Discover top Southwest attractions

The Southwest region of the United States is a paradise of natural wonders and cultural experiences that will captivate adventurous travelers. Begin your journey at the awe-inspiring Grand Canyon, where you can hike along the scenic Rim Trail or take a thrilling helicopter tour for breathtaking aerial views. Just a short drive away, the vibrant city of Sedona offers stunning red rock formations, perfect for hiking, mountain biking, or indulging in a rejuvenating spa day at one of its top-rated resorts. Don’t miss a visit to Monument Valley, where you can explore the iconic sandstone buttes on a guided tour led by Navajo guides, who share their rich cultural heritage and stories. For families, a stop at the interactive Arizona Science Center in Phoenix offers a fun and educational experience for children of all ages. End your adventure in Santa Fe, known for its Pueblo-style architecture and thriving arts scene, where you can browse local galleries and enjoy authentic Southwestern cuisine. Consider staying in upscale accommodations in Sedona or Santa Fe, where you’ll find hotels that provide attentive service and luxurious amenities, ensuring a pampered experience that caters to your high expectations.

Top Southwest Hotel Reviews

Frequently asked questions

How much do adults-only hotels in Southwest cost?
Prices for adults-only hotels in Southwest may change due to, among other perks, the star rating and amenities provided by the hotel. Whatever your budget, you'll find a grown-up getaway where you'll be able to breathe easy and relax with Expedia.
Are there any adult-only all-inclusive resorts in Southwest?
Although you won't find any adults-only all-inclusive hotels or resorts in Southwest, don't let that stop you from treating your sweetheart (and yourself!) to a romantic weekend away. Secure a room in Jackson at Fairview Inn. Amenities including premium bedding and beauty services and an atmosphere that's made for couples make it a great choice. Love is also on the menu at Old Capitol Inn. This romantic retreat in Jackson comes with wedding services, a rooftop terrace and more.
What is there to do in Southwest near my adults-only hotel?
You'll discover tons of things to keep you on the go in Southwest. If you're visiting Jackson, stop by Mississippi Children's Museum, Mississippi Civil Rights Museum and Jackson Zoological Park. Planning an escape in Natchez? Natchez Museum of African American History and Culture, Rosalie Mansion and Stanton Hall are among the best sights in this city.
How can I find cheap adults-only hotels in Southwest?
An excellent way to locate cheap adults-only hotels in Southwest is with Expedia's easy-to-use filter tool. Refine your search by amenities, star rating and budget to snag unbeatable rates in a few clicks. You can also sort the price from lowest to highest to find the most affordable stay.
From what age can you stay in an adult-only hotel in Southwest?
Adult-only resorts and hotels in Southwest usually have an age restriction of 16, 18 or 21. As regulations may differ, be sure to check the rules of the property you're interested in for accurate information. Whether you're planning a catch-up with friends or a romantic weekend getaway with your honey, Expedia can help you find an ideal adult-only stay.
Are all adult-only resorts all-inclusive in Southwest?
If you only intend to vacation at a hotel or resort where the majority of what you need is included in the room rate, make use of our "all-inclusive" filter. This will show you all the suitable adult-only all-inclusive retreats in Southwest that generally include your room, food and drinks, a variety of on-site activities and entertainment. Click on the hotel you have your eye on to discover what's included in the cost.
Why book your adults-only hotel in Southwest with Expedia?
Expedia has an excellent range of adults-only hotels at competitive rates in Southwest. Simply use our search filters to choose how much you want to spend and then sort the results by price. Whether you're planning a couples escape or want to party with pals, we'll help you find the ideal space.
When is the best time to stay at an adult-only all-inclusive resort in Southwest?
The best time to book an adult-only all-inclusive resort or hotel in Southwest depends on a few factors, one of which is the weather. Also consider whether you prefer to experience the excitement of peak season, when demand for hotels and flights is high, or the low season, when things are a bit less hectic. Weigh up your budget and travel style before booking your dream adult-only getaway that comes with all the bells and whistles!
Can I cancel or change my adult-only resort booking?
Of course. Depending on the type of booking you made and how close you are to check in, there may not be any charge. Rules can vary among our adult-only resorts and hotels, so read the fine print in your itinerary or visit Expedia's Trips portal for more information. If you'd like to make your vacation in Southwest as stress-free as possible, select adult-only accommodations that are fully refundable.

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