Title: St. Marys Vacation Packages 2026 from $639 | Expedia.com [Hotels in St. Marys](https://expedia.com/St-Marys-Hotels.d553248634983299478.Travel-Guide-Hotels)[Vacation Rentals in St. Marys](https://expedia.com/St-Marys-Vacation-Rentals.d553248634983299478.Travel-Guide-VacationRentals)[Flights to St. Marys](https://expedia.com/Cheap-Flights-To-St-Marys.d553248634983299478.Travel-Guide-Flights)[Car Rentals in St. Marys](https://expedia.com/Car-Rentals-In-St-Marys.d553248634983299478.Car-Rental-Guide) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_packages.jpeg?impolicy=fcrop&w=1200&h=300&q=medium) # St. Marys Vacations from $639 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your St. Marys Vacation The adventure-filled city of St. Marys is calling. Discover its hot spots and hidden treasures with a St. Marys vacation package that's customized to you. [Imes Bridge](https://www.expedia.com/Imes-Bridge-Iowa.d6106006.Vacation-Attraction) is one of the big-ticket attractions to put on your sightseeing agenda during a trip to St. Marys. No matter your travel plans or the size of your budget, putting together a tailored St. Marys vacation is a breeze with Expedia. ## The Latest St. Marys vacation packages Price found within the past 48 hours. Click for updated prices. ![Holiday Inn Downtown - Mercy Area by IHG](https://images.trvl-media.com/lodging/1000000/20000/18900/18835/56a1214f_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Holiday Inn Downtown - Mercy Area by IHG Downtown Des Moines $639 per person Jun 18 - Jun 22 found 18 hours ago Roundtrip non-stop flight included Boston (BOS) to Des Moines (DSM) 7.8/10 Good! (1,006 reviews) I loved the pool, It was 8-9 feet. Which is very fun to swim in. The rooms were spacious and everything was neat and comfortable. We didn't really talk with staff but they seemed nice as we were checking-in. Reviewed on Mar 25, 2026 ![Hyatt Place West Des Moines Jordan Creek](https://images.trvl-media.com/lodging/17000000/16120000/16112600/16112546/018a0ab2_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Place West Des Moines Jordan Creek $750 per person Jun 18 - Jun 22 found 18 hours ago Roundtrip non-stop flight included Boston (BOS) to Des Moines (DSM) 9.2/10 Wonderful! (1,021 reviews) Clean room, pool was nice, plenty parking. Reviewed on Mar 22, 2026 ![Hotel Fort Des Moines, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/10000/9400/9375/72ac6d3b_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hotel Fort Des Moines, Curio Collection by Hilton Downtown Des Moines $904 per person May 15 - May 19 found 17 hours ago Roundtrip flight included Burbank (BUR) to Des Moines (DSM) 9.6/10 Exceptional! (1,094 reviews) Room was clean, we were by the elevator and didn't hear other guests so very quiet. We had breakfast delivered to the room and the order was right and food was great. Staff we encountered were all very polite and respectful. Reviewed on Mar 30, 2026 ![Hilton Des Moines Downtown](https://images.trvl-media.com/lodging/22000000/21330000/21321600/21321542/3d4c6021_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hilton Des Moines Downtown Downtown Des Moines $869 per person Jun 18 - Jun 22 found 18 hours ago Roundtrip non-stop flight included Boston (BOS) to Des Moines (DSM) 9/10 Wonderful! (999 reviews) A front receptionist was repeatedly rude to the customers she managed over the phone. She was argumentative and denigrated her customers on the phone….including me. She argued with how I made my reservation - a phone call to Hilton reservations- she stated was made through a third party. That sort of rudeness required a re-think of her people-facing role. She became frustrated, her voices was raised, argumentative and simply rude. Never should she have access to customers. Reviewed on Mar 26, 2026 ![Hampton Inn Des Moines-Airport](https://images.trvl-media.com/lodging/1000000/20000/17400/17394/9e02de50_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hampton Inn Des Moines-Airport Greater South Side $799 per person Jun 18 - Jun 22 found 18 hours ago Roundtrip non-stop flight included Boston (BOS) to Des Moines (DSM) 8.8/10 Excellent! (1,007 reviews) Shuttle at front door. Reviewed on Mar 23, 2026 Don't see what you're looking for? See all available trips from Columbus to St. Marys [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-04-30/2026-05-07/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=DSM&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## St. Marys Hotel Deals ![Days Inn & Suites by Wyndham Des Moines Airport](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/fcd8bd89_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Days Inn & Suites by Wyndham Des Moines Airport 1901 Hackley Ave Des Moines IA Fully refundableReserve now, pay when you stay $66 nightly $74 total Apr 6 - Apr 7 Total with taxes and fees 8.6/10 Excellent! (1,756 reviews) Hot breakfast and comfortable rooms! Reviewed on Mar 29, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F6%2F2026&endDate=4%2F7%2F2026&selected=49826&PinnedHotelID=49826&HadPinnedHotel=true®ionId=553248634983299478) ![Hyatt Place West Des Moines Jordan Creek](https://images.trvl-media.com/lodging/17000000/16120000/16112600/16112546/018a0ab2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hyatt Place West Des Moines Jordan Creek 295 South 64th st West Des Moines IA Fully refundableReserve now, pay when you stay $99 nightly $111 total Mar 31 - Apr 1 Total with taxes and fees 9.2/10 Wonderful! (1,004 reviews) Stayed 3 nights and had a great stay, hood location close to shopping and restaurants. Reviewed on Mar 26, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F31%2F2026&endDate=4%2F1%2F2026&selected=16112546&PinnedHotelID=16112546&HadPinnedHotel=true®ionId=553248634983299478) ![Drury Inn & Suites West Des Moines](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836184/a1ae2959_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Drury Inn & Suites West Des Moines 5505 Mills Civic Pkwy West Des Moines IA Fully refundableReserve now, pay when you stay $100 nightly $112 total Apr 4 - Apr 5 Total with taxes and fees 9.4/10 Exceptional! (1,008 reviews) Good location. Reviewed on Mar 29, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F4%2F2026&endDate=4%2F5%2F2026&selected=1836184&PinnedHotelID=1836184&HadPinnedHotel=true®ionId=553248634983299478) [See all 155 properties in St. Marys](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F31%2F2026&endDate=4%2F1%2F2026®ionId=553248634983299478) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best St. Marys Vacation Packages ## St. Marys Essential Information | Language | English | | --------------- | ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | | Currency | U.S dollars | | Closest Airport | Des Moines Intl. Airport (DSM) | | Top Sights | [Lake Ahquabi State Park](https://www.expedia.com/Lake-Ahquabi-State-Park-Indianola.d553248621532648992.Vacation-Attraction), [Indianola Pickard Sports Complex](https://www.expedia.com/Indianola-Pickard-Sports-Complex-Indianola.d553248635998106930.Vacation-Attraction) and [Des Moines Metro Opera](https://www.expedia.com/Des-Moines-Metro-Opera-Indianola.d553248635998111871.Vacation-Attraction) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations 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[](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ## Frequently asked questions ### How much does a St. Marys vacation package cost? ### What are the cheapest months to go to St. Marys? ### How many days is enough for St. Marys? ### How to find the best St. Marys package deals? ### Is it cheaper to book a St. Marys vacation as a package? ### When to book a vacation package to St. Marys? ### Does Expedia offer Book Now, Pay Later St. Marys vacation packages? \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save even more - get up to 20% on select hotels when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app