St. Marys Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your St. Marys Vacation

The adventure-filled city of St. Marys is calling. Discover its hot spots and hidden treasures with a St. Marys vacation package that's customized to you. Imes Bridge is one of the big-ticket attractions to put on your sightseeing agenda during a trip to St. Marys. No matter your travel plans or the size of your budget, putting together a tailored St. Marys vacation is a breeze with Expedia.

St. Marys Hotel Deals

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $76 total per night from Nov 15 to Nov 16
$76 total
Nov 15 - Nov 16
Total with taxes and fees
Days Inn & Suites by Wyndham Des Moines Airport
AmericInn by Wyndham Des Moines Airport

AmericInn by Wyndham Des Moines Airport

3 out of 5
1920 Hackley Ave Des Moines IA
Fully refundableReserve now, pay when you stay
$64 nightly
The price is $71 total per night from Nov 19 to Nov 20
$71 total
Nov 19 - Nov 20
Total with taxes and fees
8/10 Very Good! (1,007 reviews)
"We won’t stay there again"

Reviewed on Nov 5, 2026

AmericInn by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $101 total per night from Nov 21 to Nov 22
$101 total
Nov 21 - Nov 22
Total with taxes and fees
8.8/10 Excellent! (1,001 reviews)
"The staff is always wonderful the toilet leaked in our room making carpet all wet"

Reviewed on Nov 5, 2026

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best St. Marys Vacation Packages

St. Marys Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Des Moines Intl. Airport (DSM)
Top Sights
Lake Ahquabi State Park, Indianola Pickard Sports Complex and Des Moines Metro Opera

More vacations you might like

Frequently asked questions

How much does a St. Marys vacation package cost?
Offering excellent value package deals on Expedia, you'll be pleasantly surprised at how much a vacation to St. Marys costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to St. Marys?
March, August and December are the best times to search for cheap St. Marys vacation packages. Traveling in quieter months means you can generally find reduced prices on flights and hotels.
How many days is enough for St. Marys?
The ideal length of your St. Marys vacation depends on what you'd like to see and do. Generally, a few days to a week will give you enough time to check out all the major sights and explore some hidden spots along the way.
How to find the best St. Marys package deals?
Begin your search for a St. Marys package deal by entering your destination and preferred trip dates under our "Packages" tab. Then select some filters, like "Property type" and "Guest rating," to tailor the results to your exact needs. You can also sort by "Package discount" and discover offers that come with irresistible savings. If you don't find the perfect St. Marys package deal right away, simply switch up your dates and search again. Keep in mind that deals are only available for a limited time, so book early and get your St. Marys getaway off to a flying start.
Is it cheaper to book a St. Marys vacation as a package?
You can enjoy significant savings on your St. Marys retreat by booking a personalized vacation package. Click on the "Package" heading, then enter your travel dates and destination to view the best hotel prices and airfares. Bundle everything into a neat package and you can save hundreds of dollars. Consider adding a rental car and you may land a better deal.
When to book a vacation package to St. Marys?
If you're planning an impromptu St. Marys vacation, browse our last-minute deals that can be booked up to a week before you go. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
Does Expedia offer Book Now, Pay Later St. Marys vacation packages?
If you're anything like us, you love traveling but don't love the big price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can spread the cost of your St. Marys vacation across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you spot them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.