Upstate South Carolina Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Jun 19 - Jun 21
In two months
Jul 31 - Aug 2
In three months
Aug 28 - Aug 30
In four months
Sep 25 - Sep 27

Our top choices for Upstate South Carolina vacation rentals

Interior

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (76 reviews)
"Awesome place "
United States
Jason
$139 nightly
The price is $153
Jun 7 - Jun 8
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Premium bedding, in-room safe, individually furnished, laptop workspace

Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (3 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
$234 nightly
The price is $260
Jun 9 - Jun 10
Total with taxes and fees
Carolina Camp Cedar
Terrace/patio

Luxury modern container home in a rural setting! Pet friendly!

Luxury modern container home in a rural setting! Pet friendly!
Enoree
9.2 out of 10, Wonderful, (11 reviews)
"Great communication! "
United States
Susan F.
$163 nightly
The price is $180
Jun 6 - Jun 7
Total with taxes and fees
Luxury modern container home in a rural setting! Pet friendly!
Terrace/patio

Cozy cabin in the woods! Pets welcome!

Cozy cabin in the woods! Pets welcome!
Enoree
9.8 out of 10, Exceptional, (9 reviews)
"Location felt private, yet was close to the highway. Cute little cabin."
United States
Lindsay C.
$167 nightly
The price is $185
Jun 6 - Jun 7
Total with taxes and fees
Cozy cabin in the woods! Pets welcome!
Outdoor spa tub

Lazy Bear Retreat by the Creek

Lazy Bear Retreat by the Creek
Pickens
10.0 out of 10, Exceptional, (58 reviews)
"It was a very great cozy place to stay we visited Pretty Place Chapel and enjoyed the scenery it was a great trip. "
United States
Joseph
$166 nightly
The price is $184
Jun 8 - Jun 9
Total with taxes and fees
Lazy Bear Retreat by the Creek
Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
Clemson
9.6 out of 10, Exceptional, (10 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
$214 nightly
The price is $238
Jun 7 - Jun 8
Total with taxes and fees
Clemson Memorabilia House
Fridge, microwave, oven, stovetop

The Blue Bungalow by Unity Park - Newly Renovated

The Blue Bungalow by Unity Park - Newly Renovated
Woodside Cotton Mill Village Historic District
9.8 out of 10, Exceptional, (96 reviews)
"Clean, well-stocked, great hosts!"
United States
Alyssa R.
$203 nightly
The price is $223
Jun 29 - Jun 30
Total with taxes and fees
The Blue Bungalow by Unity Park - Newly Renovated
Exterior

Historic 19th Century Cabin in Greenville

Historic 19th Century Cabin in Greenville
Greenville
9.4 out of 10, Exceptional, (11 reviews)
"unique ,cozy cabin!"
United States
Martha G.
$146 nightly
The price is $161
Jun 7 - Jun 8
Total with taxes and fees
Historic 19th Century Cabin in Greenville
Trailside Wedge Cottage | Terrace/patio

The Station by Compo Hotels

The Station by Compo Hotels
4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (19 reviews)
"Swamp rabbit trail and restaurants very close "
United States
Martin
$327 nightly
The price is $360
Jun 8 - Jun 9
Total with taxes and fees
The Station by Compo Hotels
Exterior

Gnome Hill Cottage - A Rustic Pet-Friendly Cottage In The Woods

Gnome Hill Cottage - A Rustic Pet-Friendly Cottage In The Woods
Cleveland
9.8 out of 10, Exceptional, (124 reviews)
"Fun for a remote get away. "
United States
April
$130 nightly
The price is $144
Jun 17 - Jun 18
Total with taxes and fees
Gnome Hill Cottage - A Rustic Pet-Friendly Cottage In The Woods
1 bedroom, free WiFi, bed sheets

Modern cabin near Table Rock/Pretty Place

Modern cabin near Table Rock/Pretty Place
Cleveland
10.0 out of 10, Exceptional, (77 reviews)
"What a great stay! The property was immaculate, everything was precisely as presented, the process was absolutely seamless, and our host was the best! I only wish we would have had more time on this trip to enjoy the area and the property!"
United States
John L.
$203 nightly
The price is $223
Jun 8 - Jun 9
Total with taxes and fees
Modern cabin near Table Rock/Pretty Place
Property grounds

Cabin 1/LAKE HARTWELL/Green Pond&Broyles Lndgs/Clemson/Lockable Shelter w/power

Cabin 1/LAKE HARTWELL/Green Pond&Broyles Lndgs/Clemson/Lockable Shelter w/power
Townville
10.0 out of 10, Exceptional, (115 reviews)
"This is our second time staying at cast away cabins, and we love it. The cabin is perfect with a well equipped covered cooking area outside. They have a very nice fire pit and 3 boat storage bays with gates. Can’t wait to come back! "
United States
Justin C.
$183 nightly
The price is $203
Jun 7 - Jun 8
Total with taxes and fees
Cabin 1/LAKE HARTWELL/Green Pond&Broyles Lndgs/Clemson/Lockable Shelter w/power
Property grounds

Cottage by the lakeshore with a private hot tub!

Cottage by the lakeshore with a private hot tub!
Landrum
8.6 out of 10, Excellent, (21 reviews)
"Cottage was comfortable and relaxing. Just what we needed for the weekend. "
United States
David A.
$197 nightly
The price is $210
Jun 9 - Jun 10
Total with taxes and fees
Cottage by the lakeshore with a private hot tub!
Exterior detail

Cabin 6/Cozy A-frame/LAKE HARTWELL/Green Pond&Broyles Lndgs/Clemson/Anderson

Cabin 6/Cozy A-frame/LAKE HARTWELL/Green Pond&Broyles Lndgs/Clemson/Anderson
Townville
10.0 out of 10, Exceptional, (5 reviews)
"Everything was excellent. Perfect place my husband and I for a Clemson football weekend!"
United States
Joyce P.
$172 nightly
The price is $191
Jun 7 - Jun 8
Total with taxes and fees
Cabin 6/Cozy A-frame/LAKE HARTWELL/Green Pond&Broyles Lndgs/Clemson/Anderson
Exterior

Charming cabin with AC and WiFi in delightful Clinton

Charming cabin with AC and WiFi in delightful Clinton
Clinton
9.6 out of 10, Exceptional, (5 reviews)
"It was perfect for two. Clean, quiet and relaxing. Exactly as listed. Our host was easy to contact and quick to reply. We will definitely be coming back when we are in town. "
United States
Charles L.
$135 nightly
The price is $147
Jun 29 - Jun 30
Total with taxes and fees
Charming cabin with AC and WiFi in delightful Clinton
Outdoor dining

Rainyville - Emerald: Charming cottage with loft in Walhalla, South Carolina

Rainyville - Emerald: Charming cottage with loft in Walhalla, South Carolina
Walhalla
9.8 out of 10, Exceptional, (13 reviews)
"Perfect home away from home. "
United States
Christine
$259 nightly
The price is $285
Jun 7 - Jun 8
Total with taxes and fees
Rainyville - Emerald: Charming cottage with loft in Walhalla, South Carolina
Exterior

Private Apartment on Beautiful Grounds, Walking Distance to Landrum SC

Private Apartment on Beautiful Grounds, Walking Distance to Landrum SC
Landrum
9.8 out of 10, Exceptional, (37 reviews)
"Great stay"
United States
Jahaun A.
$116 nightly
The price is $129
Jul 6 - Jul 7
Total with taxes and fees
Private Apartment on Beautiful Grounds, Walking Distance to Landrum SC
Private kitchen

2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!

2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!
Greenville
9.6 out of 10, Exceptional, (30 reviews)
"The apartment was very clean, it also has a washer and dryer which is a plus for longer stays. There's a Keurig coffee maker, which we loved. Plenty of clean towels and all the major items. We loved the location within 10 minutes of all the main attractions. We also loved the fact that it's pet friendly. "
United States
M
$164 nightly
The price is $180
Jun 8 - Jun 9
Total with taxes and fees
2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!
Exterior

Romantic Cottage Getaway, tucked peacefully in the woods

Romantic Cottage Getaway, tucked peacefully in the woods
Pickens
10.0 out of 10, Exceptional, (19 reviews)
"Amazing secluded retreat!"
United States
Stephen N.
$182 nightly
The price is $202
Jun 8 - Jun 9
Total with taxes and fees
Romantic Cottage Getaway, tucked peacefully in the woods
Fridge, microwave, oven, stovetop

Modern 2BR • Great for Work & Family - 6 Min from Downtown Greenville

Modern 2BR • Great for Work & Family - 6 Min from Downtown Greenville
Greenville
10.0 out of 10, Exceptional, (6 reviews)
"We had a great stay in this super cute home! It was perfect for what we needed while attending a conference in town for a few days. We really appreciated the heads up about the construction in the neighborhood from the host."
United States
Anonymous traveler
$199 nightly
The price is $219
Jun 15 - Jun 16
Total with taxes and fees
Modern 2BR • Great for Work & Family - 6 Min from Downtown Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Upstate South Carolina Hotel Reviews

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

10/10 Excellent
"The hotel was very clean and the staff were courteous. The hotel is always well maintained"
Jimmie 1-night trip
Posted 1 hour ago
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

Find out more about Upstate South Carolina

Everything you need to know about Upstate South Carolina vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Upstate South Carolina vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $93 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Upstate South Carolina rentals

At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia