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Upstate South Carolina Vacation Rentals

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Dec 5 - Dec 7
In two months
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Feb 13 - Feb 15
In four months
Mar 13 - Mar 15

Vacation Rentals in Upstate South Carolina

Two Bedroom Suite | 3 bedrooms, laptop workspace, iron/ironing board, free WiFi
Mint House Greenville - Downtown

Mint House Greenville - Downtown

4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (763)
"Excellent stay as always! "
United States
Elena
$123 nightly
The price is $134
Nov 30 - Dec 1
Total with taxes and fees
Mint House Greenville - Downtown
1 bedroom, individually furnished, desk, laptop workspace
stayAPT Suites Greenville-Haywood Mall

stayAPT Suites Greenville-Haywood Mall

3.0 star property
Greenville
9.2 out of 10, Wonderful, (192)
"Great place!"
United States
Daecia
$119 nightly
The price is $131
Dec 1 - Dec 2
Total with taxes and fees
stayAPT Suites Greenville-Haywood Mall
Cottage (1 Bedroom) | Front of property
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3.0 star property
Clemson
10.0 out of 10, Exceptional, (1)
Wooded Cottage - 3 Mi to Clemson University
Exterior
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

2.0 star property
Seneca
9.8 out of 10, Exceptional, (46)
"The place was absolutely magnificent."
United States
David
$129 nightly
The price is $142
Nov 20 - Nov 21
Total with taxes and fees
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2 bedrooms, free WiFi, bed sheets
Stylish Downtown Greenville Apartment 1 Block Off Main Street

Stylish Downtown Greenville Apartment 1 Block Off Main Street

2.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (4)
"Great place, great location. Short walk to downtown. "
United States
Lindsay R.
$139 nightly
The price is $153
Nov 23 - Nov 24
Total with taxes and fees
Stylish Downtown Greenville Apartment 1 Block Off Main Street
Apartment, 2 Bedrooms | Living area | 40-inch TV with digital channels
Park Place Apartments by Landing

Park Place Apartments by Landing

4.0 star property
Greenville
7.6 out of 10, Good, (41)
"Great place for a different experience Enjoyed the train "
United States
Edward
Park Place Apartments by Landing
Trailside Wedge Cottage | Terrace/patio
The Station by Compo Hotels

The Station by Compo Hotels

4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (13)
"great place perfect for more privacy vs. a standard hotel"
United States
John
$282 nightly
The price is $311
Dec 4 - Dec 5
Total with taxes and fees
The Station by Compo Hotels
Fridge, microwave, oven, stovetop
Stylish Downtown Greenville Apartment 1 Block Off Main Street

Stylish Downtown Greenville Apartment 1 Block Off Main Street

2.0 star property
Greenville Downtown
10.0 out of 10, Exceptional, (3)
"Very convenient and walkable to downtown restaurants and activities. Very clean and unique as a remodeled older home in a historic neighborhood."
United States
Brad P.
$131 nightly
The price is $144
Nov 20 - Nov 21
Total with taxes and fees
Stylish Downtown Greenville Apartment 1 Block Off Main Street
Smart TV
Lazy Bear Retreat by the Creek

Lazy Bear Retreat by the Creek

Pickens
10.0 out of 10, Exceptional, (42)
"Clean , rustic interior, nothing fancy. "
United States
Robert
$166 nightly
The price is $184
Nov 23 - Nov 24
Total with taxes and fees
Lazy Bear Retreat by the Creek
Outdoor dining
Riverwalk Falls-lovely one bedroom condo

Riverwalk Falls-lovely one bedroom condo

Greenville Downtown
10.0 out of 10, Exceptional, (171)
"An amazing location and great stay!"
United States
Amanda S.
$186 nightly
The price is $205
Nov 23 - Nov 24
Total with taxes and fees
Riverwalk Falls-lovely one bedroom condo
Fridge, microwave, oven, stovetop
Adorable & recently renovated condo within walking distance to downtown Clemson.

Adorable & recently renovated condo within walking distance to downtown Clemson.

Clemson
10.0 out of 10, Exceptional, (27)
"Clean, quiet, newly renovated. Exactly what we needed for a relaxing weekend. "
United States
Daniel
Adorable & recently renovated condo within walking distance to downtown Clemson.
Property grounds
Location, Location! Five Forks area: Simpsonville, Greenville, Greer, Mauldin

Location, Location! Five Forks area: Simpsonville, Greenville, Greer, Mauldin

Simpsonville
10.0 out of 10, Exceptional, (10)
"Just a beautiful — and beautifully decorated — little home in a fantastic location. Had everything we needed and the owners were super-kind. Loved it!"
United States
Katherine J.
Location, Location! Five Forks area: Simpsonville, Greenville, Greer, Mauldin
Property grounds
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.

Seneca
9.8 out of 10, Exceptional, (154)
"My group had a very nice stay. Everything was very well-kept and the various amenities were excellent. Thank you!"
United States
Henry W.
6 Bedrooms and 3 docks on a Lake Hartwell cove, 3 miles from Clemson by water.
Fridge, microwave, oven, stovetop
Great Getaway

Great Getaway

Clemson
10.0 out of 10, Exceptional, (22)
"Lovely, quiet and spacious yet still walkable to campus."
United States
amy
Great Getaway
Outdoor dining
Rainyville - Emerald: Charming cottage with loft in Walhalla, South Carolina

Rainyville - Emerald: Charming cottage with loft in Walhalla, South Carolina

Walhalla
9.8 out of 10, Exceptional, (10)
"Perfect home away from home. "
United States
Christine
$260 nightly
The price is $286
Nov 20 - Nov 21
Total with taxes and fees
Rainyville - Emerald: Charming cottage with loft in Walhalla, South Carolina
Fridge, microwave, oven, stovetop
Beautiful Home Close To Everything

Beautiful Home Close To Everything

Greenville
9.6 out of 10, Exceptional, (169)
"Loved the house! Great location. Fun back yard. Has everything you need for a family to have a great time. Owner is very communicative which makes the experience so much better. "
United States
Nik S.
$265 nightly
The price is $291
Nov 23 - Nov 24
Total with taxes and fees
Beautiful Home Close To Everything
Fridge, microwave, oven, stovetop
Walk to Patrick Square for dining and shopping;Spacious house,Perfect for groups

Walk to Patrick Square for dining and shopping;Spacious house,Perfect for groups

Clemson
10.0 out of 10, Exceptional, (18)
"Check-in was seamless and the house was very cozy."
United States
Amy M.
Walk to Patrick Square for dining and shopping;Spacious house,Perfect for groups
Terrace/patio
4 Bedroom Bungalow Minutes from Downtown Greenville

4 Bedroom Bungalow Minutes from Downtown Greenville

Overbrook Historic District
10.0 out of 10, Exceptional, (34)
"Property was beautifully appointed and host was super easy to work with!"
United States
Mary W.
4 Bedroom Bungalow Minutes from Downtown Greenville
Exterior
Historic 19th Century Cabin in Greenville

Historic 19th Century Cabin in Greenville

Greenville
10.0 out of 10, Exceptional, (4)
"Great cabin in the perfect location. Hosts have thought of everything. Will definitely stay here again! "
United States
David R.
$146 nightly
The price is $161
Nov 20 - Nov 21
Total with taxes and fees
Historic 19th Century Cabin in Greenville
Fridge, microwave, oven, stovetop
YELLOW DOOR 2 BEDROOM COTTAGE

YELLOW DOOR 2 BEDROOM COTTAGE

Simpsonville
9.6 out of 10, Exceptional, (60)
"It was the perfect place for me and my two kids and little Pom. We enjoyed our stay! "
United States
Bianca T.
YELLOW DOOR 2 BEDROOM COTTAGE
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

10/10 Excellent
"everything seemed brand new at this hotel. book a room with confidence "
Chris 1-night trip
Posted 1 day ago
ECHO Suites Extended Stay by Wyndham Spartanburg

Find out more about Upstate South Carolina

Everything you need to know about Upstate South Carolina vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Upstate South Carolina vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $131 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Upstate South Carolina rentals

At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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