Plan your trip
Photo by Visit Greenville, South Carolina
Check prices for these dates, December 15 – 16, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Greenville vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.
There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Greenville vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.
Whenever you want to travel, a warm welcome awaits you in Greenville. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Greenville in high season.
Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $108 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!
At Expedia, we put the best Greenville vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.
To find some top Greenville rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Greenville vacation.
If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Greenville. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.
Yes, we give you a choice of vacation rentals in Greenville close to The Peace Center, or you can select a more remote option if you'd like a relaxing place to stay. Visitors like the array of shops and scenic riverfront in Greenville. While you're here, you can also enjoy the top-notch restaurants and waterfalls.
Steps Away Downtown Douthit Greenville Getaway!: This Greenville vacation home rental is in the city center and equipped with air-conditioning and a Smart TV to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Some other homes for rent in Greenville include NEW Spacious 4-Story 4-bedroom Townhome Retreat in Greenville and 4 Mi to Dtwn: Home w/ Fire Pit in Greenville.
Expedia has 351 vacation rentals for your stay in Greenville.
The Children’s Museum of the Upstate and Greenville Zoo are a couple of family-friendly sights, whereas cultural attractions include The Peace Center and Roper Mountain Science Center. While here, Bon Secours Wellness Arena and Fluor Field at the West End are other places worth a visit.
Vacation rentals are private accommodations you can reserve for several days or more in Greenville. Vacation rentals provide amenities such as WiFi and washers and dryers so you'll have all the conveniences of home. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from shared hotel elevators and busy lobbies while still allowing you the excitement and enjoyment of travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental a popular option for a family trip or a small group gathering.