Find 5 Star Hotels in St. Charles, MO from $149

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Check availability on St. Charles 5 Star Hotels

Tonight
Aug 31 - Sep 1
Tomorrow
Sep 1 - Sep 2
Next weekend
Sep 5 - Sep 7
In two weeks
Sep 12 - Sep 14

Compare St. Charles 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (546)
"Room was very spacious. The property was immaculate and the service was attentive without be over bearing."
$519 nightly
The price is $605
Sep 21 - Sep 22
Total with taxes and fees
The Ritz-Carlton, St. Louis
Four Seasons Hotel St Louis
Rooftop bar

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1004)
"We’ve stayed at this hotel several times and keep coming back. Great hotel staff and property. "
$425 nightly
The price is $497
Sep 2 - Sep 3
Total with taxes and fees
Four Seasons Hotel St Louis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Charles.
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road, St. Louis, MO
$127 nightly
The price is $149 total per night from Sep 14 to Sep 15
$149 total
Sep 14 - Sep 15
Total with taxes and fees
8.4/10 Very Good! (1,009 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

See all hotels in St. Charles

Top St. Charles Hotel Reviews

Find out more about St. Charles

Find out more about St. Charles

Why not demand the best of accommodations during your holiday to St. Charles? After all, you love the finer things in life, both at home and when you book a getaway. You'll join the multitudes of vacationers who have made St. Charles so popular in the last year. There's no reason to delay a getaway to St. Charles any longer. We should also mention, the hotels in this area are known for guest services, so you know you'll be looked after during your getaway. Reserve one of our 5-star hotels in St. Charles and indulge in the finer things in life for a while. Don't wait any longer!

Get a Great Deal on 5-Star Hotels in St. Charles

Don't be afraid to request the best service from your hotel, along with pristine rooms. Spa treatments, delicious meals, and attentive guest service are all waiting for you. You're sure to find exactly the accommodation you need. Additionally, the hotels in this area receive high marks for customer satisfaction, so you know you'll be well cared for during your getaway. What creature comforts do you want in your lodging? A full-body massage to help your cares fall away? A concierge to help you suggest the next attraction to visit? Plush carpeting, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will astonish you. Want to see for yourself? Then explore the 353 reviews various guests have left on Expedia and get to know these places.

But you aren't going to spend your entire vacation in your room, of course. We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in St. Charles are the perfect place to rest up after an exciting day.

Your Getaway Starts Today

The results are in, and St. Charles 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. Your great getaway is just a mouse-click away. Opt for one of our St. Charles 5-star hotels today and relax in luxe surroundings tomorrow.

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Frequently asked questions

How much does it cost to stay in a 5-star hotel in St. Charles?
The amount you pay for a 5-star hotel in St. Charles depends on factors such as when you plan to go and the length of your getaway. Our top tip for bagging an awesome deal? Use our pricing filters to check out the available accommodations for your chosen dates.

  • Search for the lowest price per night from $149

What makes a hotel 5 stars in St. Charles?
From fine dining venues and 24-hour fitness centers to pools and the finest bedding, the 5-star experience in St. Charles is all about relaxation and luxury. But it calls for more than just top-notch amenities to earn a 5-star rating. Hotels also have to offer extraordinary guest-centric services like in-room massage treatments, dry cleaning and laundry and 24/7 room service.
Are there any 5-star all-inclusive resorts in St. Charles?
Use our handy filters to find a luxury retreat in St. Charles where most of what you need is included in the price. Next, refine your results for accommodations that have a rating of 5 stars and are described as "All inclusive." The most important thing on the schedule at these stays? Pure enjoyment and indulgence.