Find 4 Star Hotels in St. Charles, MO from $121

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Our top choices for St. Charles 4-star hotels

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,223 reviews)
"Wonderful stay"
United States
David
$116 nightly
The price is $138
Feb 8 - Feb 9
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.4 out of 10, Very Good, (4,011 reviews)
"Nice room & friendly staff!"
United States
Cynthia
$149 nightly
The price is $176
Feb 5 - Feb 6
Total with taxes and fees
Hyatt Regency St. Louis at The Arch

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,000 reviews)
"Great staff"
United States
irene
$130 nightly
The price is $152
Mar 1 - Mar 2
Total with taxes and fees
Hilton St. Louis Frontenac

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,592 reviews)
"Clean room and the hotel itself is just gorgeous."
United States
anthony
$138 nightly
The price is $162
Feb 12 - Feb 13
Total with taxes and fees
21C Museum Hotel St Louis

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.6 out of 10, Excellent, (1,000 reviews)
"The place is beautiful, the room is very cozy and comfortable, the hotel well located with good breakfast. "
United States
Maria
$153 nightly
The price is $182
Feb 8 - Feb 9
Total with taxes and fees
The Cheshire

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very Good, (1,071 reviews)
"Our check in was flawless as always and the staff was very friendly"
United States
Amanda
$122 nightly
The price is $143
Feb 20 - Feb 21
Total with taxes and fees
Renaissance St. Louis Airport Hotel

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1,054 reviews)
"Clean room and great staff"
United States
Chenier
$119 nightly
The price is $141
Feb 22 - Feb 23
Total with taxes and fees
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,116 reviews)
"Very nice hotel! Amazing staff and lovely rooms!"
United States
Stephanie
$149 nightly
The price is $177
Feb 12 - Feb 13
Total with taxes and fees
Live by Loews - St.Louis

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.6 out of 10, Excellent, (1,006 reviews)
"Great location "
United States
Gregory
$127 nightly
The price is $148
Feb 8 - Feb 9
Total with taxes and fees
The Westin St. Louis

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very Good, (1,000 reviews)
"What an incredible experience! The property was beautiful! Very impressive room,restaurants were top shelf and the casino was great! Definitely Recommend!"
United States
David
$193 nightly
The price is $226
Feb 8 - Feb 9
Total with taxes and fees
Ameristar Casino Resort and Spa

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very Good, (1,000 reviews)
"Good breakfast and perfect location. "
United States
Chaquita
$122 nightly
The price is $144
Feb 22 - Feb 23
Total with taxes and fees
DoubleTree by Hilton St. Louis Forest Park

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,475 reviews)
"Clean and comfy great food "
United States
Theresa A
$104 nightly
The price is $121
Feb 25 - Feb 26
Total with taxes and fees
River City Casino & Hotel

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.6 out of 10, Excellent, (1,004 reviews)
"Beautiful historic hotel with great service."
United States
Rebecca
$193 nightly
The price is $229
Feb 12 - Feb 13
Total with taxes and fees
St. Louis Union Station Hotel, Curio Collection by Hilton

Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.2 out of 10, Very Good, (1,002 reviews)
"Large room, very clean, centrally located!"
United States
David James
$152 nightly
The price is $181
Feb 12 - Feb 13
Total with taxes and fees
Marriott St. Louis Grand

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,917 reviews)
"The staff was wonderful. Very unique hotel it was awesome."
United States
Jaden
$164 nightly
The price is $195
Feb 10 - Feb 11
Total with taxes and fees
Moonrise Hotel

Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very Good, (1,001 reviews)
"The staff was great and the hotel was beautiful for location. It looked well maintained."
United States
Helen
$145 nightly
The price is $173
Feb 20 - Feb 21
Total with taxes and fees
Marriott St. Louis Airport

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,034 reviews)
"Always a pleasure to stay there it’s one of my favorite places in St. Louis. "
United States
Dorris
$111 nightly
The price is $131
Feb 12 - Feb 13
Total with taxes and fees
Hilton Pennywell St. Louis at the Arch

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (692 reviews)
"The gym was amazing! "
United States
Hannah
$135 nightly
The price is $159
Feb 22 - Feb 23
Total with taxes and fees
Le Méridien St. Louis Clayton

DoubleTree by Hilton St. Louis - Westport

DoubleTree by Hilton St. Louis - Westport
4.0 star property
Maryland Heights
8.2 out of 10, Very Good, (1,002 reviews)
"Stayed one night felt very safe here"
United States
William
$116 nightly
The price is $135
Feb 27 - Feb 28
Total with taxes and fees
DoubleTree by Hilton St. Louis - Westport

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,279 reviews)
"Room was very nice and clean, staff was excellent, breakfast was a 10!"
United States
Michael
$116 nightly
The price is $138
Feb 22 - Feb 23
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in St. Charles.
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

Urban Tree Canopy in historic Saint Charles Missouri

Top St. Charles Hotel Reviews

Find out more about St. Charles

The get-go of any well-deserved trip gets started with selecting a splendid destination. St. Charles has become a popular destination with guests because of everything it offers. However, "location, location, location" applies to more than just your destination. When you want a trip that is amazing from start to finish, you need the ideal hotel.

Accommodations as Gorgeous as the City

St. Charles saw its fair share of visitors this past year. Expedia's review section contains comments to help you decide which hotel is the perfect fit for your vacation. When you reserve a 4-star room you can breathe easy knowing that these properties aim to meet your every need. You'll never have to search long for a tasty breakfast, to sustain your workout routine, or a refreshing spa treatment during your stay, thanks to all these hotels offer. They aim to make the grounds and facilities welcoming from the minute you step onto the property and with every step across their floors. St. Charles has several wonderful hotels that create the absolute perfect vacation.

Rooms have been fashioned to keep you as comfortable as possible, with amenities like in-room coffee or tea, designer bathroom products, and, premium bedding. So, sit back and unwind. Moreover, if you find yourself in need of something more, you can trust the staff will work their best to ensure you continue to be satisfied during your stay. These hotels are so nice that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in St. Charles Today!

Your getaway to St. Charles should be a break from your daily routine. Make sure to book soon. With so few hotels, and a lot of people wanting to vacation in St. Charles, you may miss the chance to snag the perfect place.

Frequently asked questions

What are the best 4-star hotels in St. Charles?
If you're seeking high-quality comfort and lots of amenities during your St. Charles retreat, check in to Ameristar Casino Resort and Spa. This sought-after 4-star hotel comes with premium bedding and concierge services. DoubleTree by Hilton St. Louis - Westport also gets stellar reviews from Expedia guests. Concierge services and a swimming pool are among its conveniences.
How much does it cost to stay in a 4-star hotel in St. Charles?
To find a 4-star hotel in St. Charles that fits your budget, take advantage of Expedia's search and sort filters. Take a look at the availability during your chosen dates and use our pricing filter to set your limit. You can also sort your results by the most affordable option first.

  • Search for the lowest price from $485

What's the difference between 5-star and 4-star hotels in St. Charles?
If you choose to stay at a 4-star hotel in St. Charles, you'll usually find plenty of amenities to make sure you're relaxed, such as a gym, pool and restaurant. You can look forward to top-quality service and deluxe accommodations. Choose a 5-star hotel and you'll get a few more perks — think around-the-clock concierge, on-site spas and opulent turndown services. You're likely to get extra amenities and first-rate services at a 5-star retreat, though both are superb options for luxury guests.

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