Scenic view of Fountain Lakes Park, in St. Charles, MO with colorful Autumn foliage and a cloudy sky reflected in a lake

Find 4 Star Hotels in St. Charles, MO from $124

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Our top choices for St. Charles 4-star hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis
8.6 out of 10, Excellent, (4,120 reviews)
"This was one of the nicest hotels I have ever stayed at for a very affordable price. We would definitely stay here again."
United States
Elisha
$143 nightly
The price is $169
Jun 28 - Jun 29
Total with taxes and fees
Hyatt Regency St. Louis at The Arch

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley
8.4 out of 10, Very Good, (1,090 reviews)
"Great location to the airport and staff was very welcoming!"
United States
James
$135 nightly
The price is $158
Jul 9 - Jul 10
Total with taxes and fees
Renaissance St. Louis Airport Hotel

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Clayton
8.8 out of 10, Excellent, (731 reviews)
"Dinning and pool areas were enjoyable."
United States
Robert
$152 nightly
The price is $179
Jun 28 - Jun 29
Total with taxes and fees
Le Méridien St. Louis Clayton

The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End
9.0 out of 10, Wonderful, (1,001 reviews)
"Great hotel!"
United States
Terence Peter
$209 nightly
The price is $246
Jun 28 - Jun 29
Total with taxes and fees
The Royal Sonesta Chase Park Plaza St. Louis

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,916 reviews)
"Great stay!"
United States
Quentin
$148 nightly
The price is $173
Jul 19 - Jul 20
Total with taxes and fees
21C Museum Hotel St Louis

Marriott St. Louis Grand

Marriott St. Louis Grand
4.0 star property
Downtown St. Louis
8.2 out of 10, Very Good, (1,029 reviews)
"The room was nice and the staff was friendly. Perfect spot to stay if you’re going out on the town for the night."
United States
Jenna
$152 nightly
The price is $181
Jun 26 - Jun 27
Total with taxes and fees
Marriott St. Louis Grand

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,208 reviews)
"Hotel was stunning, breakfast was amazing and the location was perfect!"
United States
Julie
$156 nightly
The price is $186
Jul 5 - Jul 6
Total with taxes and fees
Live by Loews - St.Louis

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1,615 reviews)
"Would stay again in a heartbeat!"
United States
Austin
$106 nightly
The price is $124
Jul 5 - Jul 6
Total with taxes and fees
River City Casino & Hotel

Hilton St. Louis at the Ballpark

Hilton St. Louis at the Ballpark
4.0 star property
Downtown St. Louis
7.6 out of 10, Good, (1,169 reviews)
"Beautiful hotel"
United States
Zoobin
$171 nightly
The price is $204
Jun 28 - Jun 29
Total with taxes and fees
Hilton St. Louis at the Ballpark

The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,001 reviews)
"Great unique hotel."
United States
Michelle
$161 nightly
The price is $191
Jun 28 - Jun 29
Total with taxes and fees
The Cheshire

Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (1,968 reviews)
"Super convenient location, friendly staff, cool decor! Will definitely stay here again."
United States
Lindsay
$178 nightly
The price is $212
Jul 19 - Jul 20
Total with taxes and fees
Moonrise Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,310 reviews)
"The staff is wonderful, helpful, and friendly. Great bar and great location. I would definitely stay here again."
United States
Marlynn
$108 nightly
The price is $128
Jul 5 - Jul 6
Total with taxes and fees
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,003 reviews)
"Great stay!"
United States
Matiah
$189 nightly
The price is $221
Jul 5 - Jul 6
Total with taxes and fees
Ameristar Casino Resort and Spa

The Westin St. Louis

The Westin St. Louis
4.5 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,000 reviews)
"The staff was pleasant and the property was clean."
United States
Bayyan
$131 nightly
The price is $153
Jul 5 - Jul 6
Total with taxes and fees
The Westin St. Louis

Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,026 reviews)
"Great staff clean property nice location"
United States
Karen
$133 nightly
The price is $158
Jul 5 - Jul 6
Total with taxes and fees
Drury Plaza Hotel St. Louis Brentwood

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End
8.2 out of 10, Very Good, (1,002 reviews)
"Beautiful hotel in a convenient locations. Walking distance to great restaurants and coffee shops."
United States
Gary
$130 nightly
The price is $154
Jul 2 - Jul 3
Total with taxes and fees
DoubleTree by Hilton St. Louis Forest Park

St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West
8.6 out of 10, Excellent, (1,018 reviews)
"Great stay and so much to do close by!"
United States
Rachel
$159 nightly
The price is $189
Jul 1 - Jul 2
Total with taxes and fees
St. Louis Union Station Hotel, Curio Collection by Hilton

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,087 reviews)
$130 nightly
The price is $154
Jul 5 - Jul 6
Total with taxes and fees
Hilton Pennywell St. Louis at the Arch

Marriott St. Louis Airport

Marriott St. Louis Airport
4.0 star property
Edmundson
8.0 out of 10, Very Good, (1,002 reviews)
"Lovely"
United States
Yvonne
$140 nightly
The price is $167
Jul 4 - Jul 5
Total with taxes and fees
Marriott St. Louis Airport

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1,316 reviews)
"Definitely would stay again."
United States
Travis
$122 nightly
The price is $145
Jun 28 - Jun 29
Total with taxes and fees
Embassy Suites by Hilton St. Louis Downtown
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Explore similar 5-star hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

Stroll down Historic Main Street, where 1812-era charm meets modern boutiques and eateries. Bike the scenic Katy Trail or try your luck at Ameristar Casino before exploring the Lewis & Clark Boathouse.

Dramatic sunrise panoramic view of the Veterans Memorial Bridge over the Missouri River at St. Charles, MO

Top St. Charles Hotel Reviews

Find out more about St. Charles

The get-go of any well-deserved trip gets started with selecting a splendid destination. St. Charles has become a popular destination with guests because of everything it offers. However, "location, location, location" applies to more than just your destination. When you want a trip that is amazing from start to finish, you need the ideal hotel.

Accommodations as Gorgeous as the City

St. Charles saw its fair share of visitors this past year. Expedia's review section contains comments to help you decide which hotel is the perfect fit for your vacation. When you reserve a 4-star room you can breathe easy knowing that these properties aim to meet your every need. You'll never have to search long for a tasty breakfast, to sustain your workout routine, or a refreshing spa treatment during your stay, thanks to all these hotels offer. They aim to make the grounds and facilities welcoming from the minute you step onto the property and with every step across their floors. St. Charles has several wonderful hotels that create the absolute perfect vacation.

Rooms have been fashioned to keep you as comfortable as possible, with amenities like in-room coffee or tea, designer bathroom products, and, premium bedding. So, sit back and unwind. Moreover, if you find yourself in need of something more, you can trust the staff will work their best to ensure you continue to be satisfied during your stay. These hotels are so nice that you'll regret the day you have to check-out.

Reserve a 4-Star Hotel in St. Charles Today!

Your getaway to St. Charles should be a break from your daily routine. Make sure to book soon. With so few hotels, and a lot of people wanting to vacation in St. Charles, you may miss the chance to snag the perfect place.

Frequently asked questions

What are the best 4-star hotels in St. Charles?
If you're seeking high-quality comfort and lots of amenities during your St. Charles retreat, check in to Ameristar Casino Resort and Spa. This sought-after 4-star hotel comes with premium bedding and concierge services. DoubleTree by Hilton St. Louis - Westport also gets stellar reviews from Expedia guests. Concierge services and a swimming pool are among its conveniences.
How much does it cost to stay in a 4-star hotel in St. Charles?
To find a 4-star hotel in St. Charles that fits your budget, take advantage of Expedia's search and sort filters. Take a look at the availability during your chosen dates and use our pricing filter to set your limit. You can also sort your results by the most affordable option first.

  • Search for the lowest price from $415

What's the difference between 5-star and 4-star hotels in St. Charles?
If you choose to stay at a 4-star hotel in St. Charles, you'll usually find plenty of amenities to make sure you're relaxed, such as a gym, pool and restaurant. You can look forward to top-quality service and deluxe accommodations. Choose a 5-star hotel and you'll get a few more perks — think around-the-clock concierge, on-site spas and opulent turndown services. You're likely to get extra amenities and first-rate services at a 5-star retreat, though both are superb options for luxury guests.

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