Top 10 Hotels in Lilbourn, MO (from $58) 2026 - Competitive Prices

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Our top choices for Lilbourn hotels

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

A hotel with a central entrance, multiple parking spaces, and a well-lit facade.

A modern kitchen with a stone backsplash, a dining area with red chairs, and a red accent wall with a framed picture.

A room with a brown leather sofa, a red chair, and a cityscape painting on the wall.

1. Super 8 By Wyndham Marston

Marston

Brenda

$56 nightly

$64 total

Oct 21 - Oct 22

Total with taxes and fees

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

2. Hampton Inn Sikeston

Sikeston

Lori

$102 nightly

$116 total

Oct 18 - Oct 19

Total with taxes and fees

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A kitchenette with a coffee machine, a kettle, and storage shelves.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

$93 nightly

$106 total

Oct 18 - Oct 19

Total with taxes and fees

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

4. Drury Inn & Suites Sikeston, MO

Sikeston

Tim

$94 nightly

$108 total

Oct 25 - Oct 26

Total with taxes and fees

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

5. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

$101 nightly

$115 total

Oct 25 - Oct 26

Total with taxes and fees

An outdoor bar area with a modern design, featuring a counter, bar stools, and a seating area with chairs.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

6. TownePlace Suites by Marriott Sikeston

Sikeston

Rubin

$109 nightly

$124 total

Oct 22 - Oct 23

Total with taxes and fees

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.

A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

A modern kitchen with stainless steel appliances, wooden cabinets, and a bright yellow accent wall.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Craig

$58 nightly

$66 total

Oct 19 - Oct 20

Total with taxes and fees

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

8. Best Western Plus Sikeston I-55

Sikeston

Shelley

$85 nightly

$97 total

Nov 1 - Nov 2

Total with taxes and fees

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A spacious room with a large dining table and chairs, a kitchenette area, and a television mounted on the wall.

A spacious lobby with a central atrium, a piano, and a reception desk.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

9. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

$66 nightly

$76 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

A motel with a covered entrance, multiple rooms, and a parking lot.

10. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

Laura

$57 nightly

$65 total

Oct 21 - Oct 22

Total with taxes and fees

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A living room with two sofas, a coffee table, a TV, and a cabinet.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

11. Comfort Inn & Suites Sikeston I-55

Sikeston

Kathryn

$79 nightly

$90 total

Nov 8 - Nov 9

Total with taxes and fees

A hotel room with two beds, a television, a desk, and a mirror.

A motel with a covered outdoor seating area and a parking lot.

A bathroom with a sink, mirror, and chair.

A hotel room with a bed, a desk, a television, and a seating area with a small table.

12. Travel Inn Marston I-55 by Hotel O

Marston

Frank

$54 nightly

$61 total

Oct 18 - Oct 19

Total with taxes and fees

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A swimming pool with clear blue water, surrounded by sun loungers and a lifeguard stand.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

13. Hampton Inn By Hilton Dexter

Dexter

Bryan

$98 nightly

$111 total

Oct 25 - Oct 26

Total with taxes and fees

A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.

An indoor swimming pool with multiple lanes, surrounded by seating areas and tables.

Two grey armchairs with green cushions, a small side table with a white lamp, and wall-mounted sconces.

A gym with treadmills, elliptical machines, and a mirrored wall.

14. Drury Inn & Suites Hayti Caruthersville

Hayti

Cynthia

$98 nightly

$112 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A reception area with a counter, a coffee machine, and seating.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

A bathroom with a bathtub, toilet, and shower curtain.

15. Country Yard Inn and Suite

Sikeston

William

$54 nightly

$61 total

Oct 20 - Oct 21

Total with taxes and fees

A hotel room with a dark wooden desk, a television, a lamp, a chair, and a mirror on the wall.

A bathroom with a bathtub, a toilet, and a sink.

A parking lot with a grassy area and trees in the background.

A parking space marked with a wheelchair accessibility symbol.

16. Reelfoot Lake Inn

Tiptonville

Danny

$54 nightly

$62 total

Nov 1 - Nov 2

Total with taxes and fees

A diner with booth seating, a checkered floor, and a counter with a cash register.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

A reception area with a marble counter, potted plants, a clock, and a TV on the wall.

A hotel room with a bed, a desk, a chair, a large mirror, a sink, and a trash bin.

17. Travelodge by Wyndham Dexter

Dexter

Steven

$86 nightly

$97 total

Nov 1 - Nov 2

Total with taxes and fees

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A hotel room with two beds, a desk with a lamp, a chair, a dresser, and a door with a handle.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

18. Dexter Inn

Dexter

Edward

$69 nightly

$78 total

Oct 16 - Oct 17

Total with taxes and fees

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

19. Econo Lodge Dexter

Dexter

Herman

$51 nightly

$58 total

Nov 14 - Nov 15

Total with taxes and fees

A hotel breakfast area with a buffet setup, including a refrigerator, coffee machine, and various food items.

A lobby with a reception desk, seating area, and a television mounted on the wall.

A hotel entrance with a covered driveway, stone pillars, and a sign indicating a clearance of 12 feet.

A lobby with a reception desk, a flat-screen TV, seating area with chairs and ottomans, and potted plants.

20. Quality Inn Hayti North

Hayti

Winston

$59 nightly

$67 total

Nov 1 - Nov 2

Total with taxes and fees

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Top Lilbourn Hotel Reviews

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Very friendly & professional staff. Trustworthy room attendants, with attention to details. Beds comfortable. Everyone enjoyed the morning breakfast, with a good menu. Cocktail hour widely attended. Would definitely stay here again!"

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent

"We have visited the area many times in the past few years and have had terrible luck at hotels all around the area. This was such a breath of fresh air. The property was beautiful, the room was super clean, the staff was so pleasant and helpful. Breakfast was tasty and the bed was super comfortable. We have found out hotel when we come to town."

Hampton Inn Sikeston

10/10 Excellent

"Everyone was so nice. The rooms were clean and the breakfast had a good variety ."

Hampton Inn By Hilton Dexter

8/10 Good

"I was disappointed that there was no Bible in my room. I would hope they would consider putting Bibles in each room."

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent

"good, clean, affordable :)"

Reelfoot Lake Inn

8/10 Good

"Dated but descent."

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8/10 Good

"Easy parking, our bathroom sink was leaning forward and we had to place our soap in the sink so it didn't slide on the floor."

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent

"Clean, comfortable room. Nice staff and good breakfast choices."

The Dragonfly - Sleeps up to 8, Lake views.

10/10 Excellent

"This was the perfect place for us to stay when we were in town for the real foot art and craft show the house was clean. Nice size. We loved the views we had. A a fire that we sat around with and did some mores. It was just wonderful Kristi the host was awesome, very responsive and helpful. Hope to stay there again in the future!"

More cheap stays in Lilbourn

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

$57 nightly

$65 total

Oct 21 - Oct 22

Total with taxes and fees

7/10 Good! (687 reviews)

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

$66 nightly

$76 total

Nov 1 - Nov 2

Total with taxes and fees

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

$85 nightly

$97 total

Nov 1 - Nov 2

Total with taxes and fees

8.4/10 Very Good! (1,000 reviews)

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO

$93 nightly

$106 total

Oct 18 - Oct 19

Total with taxes and fees

8.8/10 Excellent! (517 reviews)

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

$102 nightly

$116 total

Oct 18 - Oct 19

Total with taxes and fees

9/10 Wonderful! (638 reviews)

New Orleans Inn Portageville

600 US-61 Portageville MO

Get rates

8/10 Very Good! (798 reviews)

Hotels in Lilbourn with star-rating

Frequently asked questions

What is the best area to stay in Lilbourn?

The best area to stay in Lilbourn is near the intersection of US-61 and US-62, as this is where you'll find the most amenities and convenient access to the surrounding region.This central area of Lilbourn is primarily characterized by its easy access to major roadways, making it ideal for travelers passing through or using Lilbourn as a base for exploring southeastern Missouri. While it's a smaller town, this intersection offers the most concentration of services, including dining options and local businesses.For travelers seeking convenience, especially those on a road trip, this area is a practical choice. The proximity to US-61 and US-62 means less time navigating local streets and more time on your journey or at your destination.

When is the best time to go to Lilbourn?

The best time to go to Lilbourn is during the spring (April to May) and fall (September to October) months.These seasons offer pleasant weather, with moderate temperatures and lower humidity, making it comfortable for outdoor activities and exploring the local area. Spring brings blooming dogwood trees and azaleas, while fall showcases colorful foliage, providing a scenic backdrop for your visit.Families often find these times ideal for visiting, as the mild weather is superb for enjoying local parks or taking day trips to nearby natural attractions without the extreme heat of summer or the chill of winter.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lilbourn.

How much is the nightly rate at a Lilbourn hotel?

Prices for hotels in Lilbourn often vary, but you can find a great deal from $58 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Find hotels in Lilbourn, MO from $58

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Lilbourn

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lilbourn hotels

1. Super 8 By Wyndham Marston

2. Hampton Inn Sikeston

3. Holiday Inn Express & Suites Sikeston Southwest by IHG

4. Drury Inn & Suites Sikeston, MO

5. Fairfield Inn & Suites by Marriott Sikeston

6. TownePlace Suites by Marriott Sikeston

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

8. Best Western Plus Sikeston I-55

9. Days Inn and Suites by Wyndham Sikeston

10. Super 8 by Wyndham Sikeston/Miner Area

11. Comfort Inn & Suites Sikeston I-55

12. Travel Inn Marston I-55 by Hotel O

13. Hampton Inn By Hilton Dexter

14. Drury Inn & Suites Hayti Caruthersville

15. Country Yard Inn and Suite

16. Reelfoot Lake Inn

17. Travelodge by Wyndham Dexter

18. Dexter Inn

19. Econo Lodge Dexter

20. Quality Inn Hayti North

Top Lilbourn Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Hayti Caruthersville

Hampton Inn Sikeston

Hampton Inn By Hilton Dexter

Super 8 by Wyndham Sikeston/Miner Area

Reelfoot Lake Inn

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Holiday Inn Express & Suites Sikeston Southwest by IHG

The Dragonfly - Sleeps up to 8, Lake views.

More cheap stays in Lilbourn

Super 8 by Wyndham Sikeston/Miner Area

Days Inn and Suites by Wyndham Sikeston

Best Western Plus Sikeston I-55

Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn Sikeston

New Orleans Inn Portageville

Hotels in Lilbourn with star-rating

Frequently asked questions

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