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Find hotels in Lilbourn, MO from $57

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    Check prices for these dates, December 14 – 15, 2026

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    Our top choices for Lilbourn hotels

    1. Super 8 By Wyndham Marston

    A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

    2. Holiday Inn Express & Suites Sikeston Southwest by IHG

    A buffet with various food items, including omelets and baked goods, served in metal containers.

    3. Drury Inn & Suites Sikeston, MO

    An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

    4. Hampton Inn Sikeston

    A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

    5. Fairfield Inn & Suites by Marriott Sikeston

    An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

    6. Best Western Plus Sikeston I-55

    A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

    7. TownePlace Suites by Marriott Sikeston

    Property amenity

    8. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

    A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

    9. Days Inn and Suites by Wyndham Sikeston

    A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

    10. Comfort Inn & Suites Sikeston I-55

    A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

    11. Travel Inn Marston I-55 by Hotel O

    A hotel lobby with a glass table and checkered chairs, an exit door, and a vending machine.

    12. Hampton Inn By Hilton Dexter

    A modern hotel lobby with a central dining area, a minibar, and a view of the outdoors.

    13. Drury Inn & Suites Hayti Caruthersville

    A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.

    14. Super 8 by Wyndham Sikeston/Miner Area

    A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

    15. Country Yard Inn and Suite

    A hotel room with two beds, a desk, a chair, a TV, and a mirror.

    16. Reelfoot Lake Inn

    A hotel room with a dark wooden desk, a television, a lamp, a chair, and a mirror on the wall.

    17. Quality Inn Hayti North

    A hotel breakfast area with a buffet setup, including a refrigerator, coffee machine, and various food items.

    18. Econo Lodge Dexter

    A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

    19. Travelodge by Wyndham Dexter

    A diner with booth seating, a checkered floor, and a counter with a cash register.

    20. Dexter Inn

    A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Top Lilbourn Hotel Reviews

    Drury Inn & Suites Sikeston, MO

    An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

    Hampton Inn Sikeston

    A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

    Holiday Inn Express & Suites Sikeston Southwest by IHG

    A buffet with various food items, including omelets and baked goods, served in metal containers.

    Drury Inn & Suites Hayti Caruthersville

    A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.

    Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

    A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

    Comfort Inn & Suites Sikeston I-55

    A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

    Days Inn and Suites by Wyndham Sikeston

    A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

    Reelfoot Lake Inn

    A hotel room with a dark wooden desk, a television, a lamp, a chair, and a mirror on the wall.

    Dexter Inn

    A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

    Frequently Asked Questions

    What is the best area to stay in Lilbourn?

    The best area to stay in Lilbourn is near the intersection of US-61 and US-62, as this is where you'll find the most amenities and convenient access to the surrounding region.

    This central area of Lilbourn is primarily characterized by its easy access to major roadways, making it ideal for travelers passing through or using Lilbourn as a base for exploring southeastern Missouri. While it's a smaller town, this intersection offers the most concentration of services, including dining options and local businesses.

    For travelers seeking convenience, especially those on a road trip, this area is a practical choice. The proximity to US-61 and US-62 means less time navigating local streets and more time on your journey or at your destination.

    When is the best time to go to Lilbourn?

    The best time to go to Lilbourn is during the spring (April to May) and fall (September to October) months.

    These seasons offer pleasant weather, with moderate temperatures and lower humidity, making it comfortable for outdoor activities and exploring the local area. Spring brings blooming dogwood trees and azaleas, while fall showcases colorful foliage, providing a scenic backdrop for your visit.

    Families often find these times ideal for visiting, as the mild weather is superb for enjoying local parks or taking day trips to nearby natural attractions without the extreme heat of summer or the chill of winter.

    Can I cancel my hotel reservation on Expedia?

    You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lilbourn.

    How much is the nightly rate at a Lilbourn hotel?

    Prices for hotels in Lilbourn often vary, but you can find a great deal from $57 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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