Top 10 Hotels in Lilbourn, MO (from $49) 2026 - Competitive Prices

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Our top choices for Lilbourn hotels

A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

A modern kitchen with a built-in microwave, a black refrigerator, and a wooden countertop.

A modern kitchen with a stone backsplash, a dining area with red chairs, and a red accent wall with a framed picture.

A hotel with a central entrance, multiple parking spaces, and a well-lit facade.

1. Super 8 By Wyndham Marston

Marston

Wendy

$56 nightly

$64 total

Oct 27 - Oct 28

Total with taxes and fees

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

2. Drury Inn & Suites Sikeston, MO

Sikeston

Tim

$94 nightly

$108 total

Nov 1 - Nov 2

Total with taxes and fees

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

A Hampton Inn hotel with a modern facade, a stone entrance, and a well-lit entrance area.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

3. Hampton Inn Sikeston

Sikeston

Deborah

$95 nightly

$108 total

Nov 22 - Nov 23

Total with taxes and fees

A buffet with various food items, including omelets and baked goods, served in metal containers.

An indoor swimming pool with a tiled floor, a lifeguard chair, and a pool ladder.

A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.

A reception area with a reception desk, a large wall-mounted sign, and a potted plant.

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

Melissa

$97 nightly

$110 total

Nov 1 - Nov 2

Total with taxes and fees

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

5. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Roslyn

$101 nightly

$115 total

Nov 8 - Nov 9

Total with taxes and fees

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

6. TownePlace Suites by Marriott Sikeston

Sikeston

Rubin

$109 nightly

$124 total

Nov 5 - Nov 6

Total with taxes and fees

A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

A reception area with a wooden reception desk, a large painting on the wall, and a potted plant.

A hotel with a covered entrance, a sign indicating a restaurant, and a well-lit parking area.

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and large windows providing natural light.

7. Best Western Plus Sikeston I-55

Sikeston

Shelley

$80 nightly

$91 total

Nov 8 - Nov 9

Total with taxes and fees

A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

A spacious lobby with a central atrium, a piano, and a reception desk.

A Days Inn hotel with a brick facade, large windows, and a sign above the entrance.

8. Days Inn and Suites by Wyndham Sikeston

Sikeston

David

$66 nightly

$76 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

A Travel Inn and Suites with a brick facade, a flat roof, and a welcoming entrance.

A reception area with a sign for 'Travel Inn and Suites' and a counter with a computer and a phone.

A living room with a sofa, two chairs, a coffee table, a television, and a window with blinds.

9. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Sikeston

Craig

$61 nightly

$70 total

Nov 8 - Nov 9

Total with taxes and fees

A hotel lobby with a glass table and checkered chairs, an exit door, and a vending machine.

A bathroom with a sink, mirror, and chair.

A hotel room with a bed, a desk, a television, and a seating area with a small table.

A hotel room with two beds, a television, a desk, and a mirror.

10. Travel Inn Marston I-55 by Hotel O

Marston

Frank

$43 nightly

$49 total

Nov 2 - Nov 3

Total with taxes and fees

A modern hotel lobby with a central dining area, a minibar, and a view of the outdoors.

A Hampton Inn hotel with a modern design, featuring a flat roof and a prominent signage.

A swimming pool with a clear view of the outdoors, surrounded by lounge chairs and a changing room.

A modern kitchen with a bar area, bar stools, wine bottles, and a large TV.

11. Hampton Inn By Hilton Dexter

Dexter

Bryan

$98 nightly

$111 total

Nov 1 - Nov 2

Total with taxes and fees

A spacious lobby with a modern design, featuring a seating area with patterned armchairs and a round table, a large window, and a fireplace with decorative wall art.

Two grey armchairs with green cushions, a small side table with a white lamp, and wall-mounted sconces.

A gym with treadmills, elliptical machines, and a mirrored wall.

An indoor swimming pool with multiple lanes, surrounded by seating areas and tables.

12. Drury Inn & Suites Hayti Caruthersville

Hayti

Philip

$98 nightly

$112 total

Nov 1 - Nov 2

Total with taxes and fees

A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

A hot tub area with a tiled floor, a wooden deck surrounding the tub, and a view of the sky through large windows.

A hotel room with a bed, a desk with a TV, a chair, a bathroom with a bathtub, and a window with curtains.

A hotel lobby with a reception desk, seating area, and large windows offering a view of the outdoors.

13. Comfort Inn & Suites Sikeston I-55

Sikeston

Fred

$87 nightly

$99 total

Nov 15 - Nov 16

Total with taxes and fees

A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

A hotel room with two beds, a sofa, a coffee table, and artwork on the walls.

A motel with a covered entrance, multiple rooms, and a parking lot.

A hotel room with a flat-screen TV, a microwave, a coffee maker, a dining table, and two sofas.

14. Super 8 by Wyndham Sikeston/Miner Area

Sikeston

Laura

$58 nightly

$66 total

Nov 5 - Nov 6

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

A reception area with a counter, a coffee machine, and seating.

15. Country Yard Inn and Suite

Sikeston

Marianne

$52 nightly

$59 total

Oct 27 - Oct 28

Total with taxes and fees

A hotel room with a dark wooden desk, a television, a lamp, a chair, and a mirror on the wall.

A building with multiple floors and a flat roof, surrounded by a grassy area with trees.

A parking lot with a grassy area and trees in the background.

A parking space marked with a wheelchair accessibility symbol.

16. Reelfoot Lake Inn

Tiptonville

Danny

$54 nightly

$62 total

Nov 7 - Nov 8

Total with taxes and fees

A hotel breakfast area with a buffet setup, including a refrigerator, coffee machine, and various food items.

A lobby with a reception desk, seating area, and a television mounted on the wall.

A hotel entrance with a covered driveway, stone pillars, and a sign indicating a clearance of 12 feet.

A lobby with a reception desk, a flat-screen TV, seating area with chairs and ottomans, and potted plants.

17. Quality Inn Hayti North

Hayti

Douglas

$61 nightly

$70 total

Nov 25 - Nov 26

Total with taxes and fees

A diner with booth seating, a checkered floor, and a counter with a cash register.

A reception area with a marble counter, potted plants, a clock, and a TV on the wall.

A lobby with a round rug, two potted plants, three framed artworks, and two black leather chairs.

A gym with multiple exercise machines, a clock on the wall, and a window with blinds.

18. Travelodge by Wyndham Dexter

Dexter

Steven

$83 nightly

$94 total

Nov 1 - Nov 2

Total with taxes and fees

A coffee shop with a coffee machine, espresso cups, a sink, and a trash bin.

A hotel hallway with patterned carpet, light green walls, and a ceiling with recessed lighting.

A kitchen with a white microwave, a fruit basket, a coffee maker, and a storage container.

A hotel lobby with a reception desk, a waiting area with a sofa and armchairs, and a patterned carpet.

19. Dexter Inn

Dexter

Edward

$61 nightly

$70 total

Nov 26 - Nov 27

Total with taxes and fees

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A hotel with a brick facade, multiple windows, and a covered entrance area.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

A living room with a sofa, a coffee table, a clock, and a painting on the wall.

20. Econo Lodge Dexter

Dexter

Herman

$51 nightly

$58 total

Nov 25 - Nov 26

Total with taxes and fees

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Top Lilbourn Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

10/10 Excellent

"Great stay. Highly recommended11 Only problem was getting there, which is not hotels fault!!"

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

10/10 Excellent

"Room was very clean and staff was kind and helpful"

For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier.

8/10 Good

"Host was great, inside of the house was clean but had some places in walls where looked like it had been hit or something and busted. Outside was not clean at all. If we were rating on a 5 star scale of clean, inside I’d give a 5 outside a 2-3 at best. We still had fun once got outside decent and host was great to respond. We’d most likely stay again and dock was nice and large. Awesome that they had games and some history of reelfoot lake stuff available to read as well. Nice firepit outside as well. Personally I loved how responsive the host was and how helpful if we had questions about the area."

Holiday Inn Express & Suites Sikeston Southwest by IHG

10/10 Excellent

"We had a nice overnight stay here. The sleeper/sofa was not comfortable, but very few are. It was a good selection of foods for the breakfast. We especially enjoyed the coffee machine that freshly grinds the coffee beans and brews it immediately. We also liked the style of the luggage carts. They were less bulky and easier to handle."

Super 8 By Wyndham Marston

8/10 Good

"It was good for an overnight stay - inexpensive, in a pretty spot - we enjoyed going for a walk."

Hampton Inn By Hilton Dexter

10/10 Excellent

"I loved this property! They had everything I look for. Indoor pool was spotless & stocked well with towels. We enjoyed the layout of the lobby, bar & eating area with multiple big screens & gift shop with frozen food & treats for those that get a little hungry. Our room & bathroom were spacious & well designed. We travel with our pup so we were very happy with the area on 2 sides with grassy areas & dog baggy collection to keep the yard clean for all dog walkers. It was the most area I’ve seen allocated for guest’s pets."

Hampton Inn Sikeston

10/10 Excellent

"Great hotel, clean spacious room, good breakfast choice"

Quality Inn Hayti North

10/10 Excellent

"Parking"

The Dragonfly - Sleeps up to 8, Lake views.

10/10 Excellent

"This was the perfect place for us to stay when we were in town for the real foot art and craft show the house was clean. Nice size. We loved the views we had. A a fire that we sat around with and did some mores. It was just wonderful Kristi the host was awesome, very responsive and helpful. Hope to stay there again in the future!"

More cheap stays in Lilbourn

Super 8 by Wyndham Sikeston/Miner Area

2609 E Malone Ave Sikeston MO

$58 nightly

$66 total

Nov 5 - Nov 6

Total with taxes and fees

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

100 Matthews Lane Sikeston MO

$61 nightly

$70 total

Nov 8 - Nov 9

Total with taxes and fees

8.4/10 Very Good! (829 reviews)

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO

$66 nightly

$76 total

Nov 1 - Nov 2

Total with taxes and fees

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

$80 nightly

$91 total

Nov 8 - Nov 9

Total with taxes and fees

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

$95 nightly

$108 total

Nov 22 - Nov 23

Total with taxes and fees

9/10 Wonderful! (649 reviews)

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO

$97 nightly

$110 total

Nov 1 - Nov 2

Total with taxes and fees

8.8/10 Excellent! (519 reviews)

Hotels in Lilbourn with star-rating

Frequently asked questions

What is the best area to stay in Lilbourn?

The best area to stay in Lilbourn is near the intersection of US-61 and US-62, as this is where you'll find the most amenities and convenient access to the surrounding region.This central area of Lilbourn is primarily characterized by its easy access to major roadways, making it ideal for travelers passing through or using Lilbourn as a base for exploring southeastern Missouri. While it's a smaller town, this intersection offers the most concentration of services, including dining options and local businesses.For travelers seeking convenience, especially those on a road trip, this area is a practical choice. The proximity to US-61 and US-62 means less time navigating local streets and more time on your journey or at your destination.

When is the best time to go to Lilbourn?

The best time to go to Lilbourn is during the spring (April to May) and fall (September to October) months.These seasons offer pleasant weather, with moderate temperatures and lower humidity, making it comfortable for outdoor activities and exploring the local area. Spring brings blooming dogwood trees and azaleas, while fall showcases colorful foliage, providing a scenic backdrop for your visit.Families often find these times ideal for visiting, as the mild weather is superb for enjoying local parks or taking day trips to nearby natural attractions without the extreme heat of summer or the chill of winter.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Lilbourn.

How much is the nightly rate at a Lilbourn hotel?

Prices for hotels in Lilbourn often vary, but you can find a great deal from $49 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Find hotels in Lilbourn, MO from $49

Upfront pricing

Treat yourself

Be picky

Go beyond your typical stay in Lilbourn

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Lilbourn hotels

1. Super 8 By Wyndham Marston

2. Drury Inn & Suites Sikeston, MO

3. Hampton Inn Sikeston

4. Holiday Inn Express & Suites Sikeston Southwest by IHG

5. Fairfield Inn & Suites by Marriott Sikeston

6. TownePlace Suites by Marriott Sikeston

7. Best Western Plus Sikeston I-55

8. Days Inn and Suites by Wyndham Sikeston

9. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

10. Travel Inn Marston I-55 by Hotel O

11. Hampton Inn By Hilton Dexter

12. Drury Inn & Suites Hayti Caruthersville

13. Comfort Inn & Suites Sikeston I-55

14. Super 8 by Wyndham Sikeston/Miner Area

15. Country Yard Inn and Suite

16. Reelfoot Lake Inn

17. Quality Inn Hayti North

18. Travelodge by Wyndham Dexter

19. Dexter Inn

20. Econo Lodge Dexter

Top Lilbourn Hotel Reviews

Drury Inn & Suites Hayti Caruthersville

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier.

Holiday Inn Express & Suites Sikeston Southwest by IHG

Super 8 By Wyndham Marston

Hampton Inn By Hilton Dexter

Hampton Inn Sikeston

Quality Inn Hayti North

The Dragonfly - Sleeps up to 8, Lake views.

More cheap stays in Lilbourn

Super 8 by Wyndham Sikeston/Miner Area

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Days Inn and Suites by Wyndham Sikeston

Best Western Plus Sikeston I-55

Hampton Inn Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Hotels in Lilbourn with star-rating

Frequently asked questions

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