Title: Midsize Car Rentals in Santiago Island - Expedia.com ![](https://images.trvl-media.com/place/6336382/a64f32d4-e200-431c-89af-7a17c4de4f0e.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Midsize Car Rental Companies in Santiago Island Photo by Sarah Mack - ![protection illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__protection.svg) ### Change your mind Penalty-free cancellation on many/select car rentals - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Treat yourself One Key members save 10% or more on over 1 million car rentals [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![package illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__package.svg) ### Shop smart Compare car suppliers and package your flight, hotel, and car to save ## Find Cheap Midsize Car Deals for Santiago Island \* Price found within the past 6 days. Click for updated prices. ### Don't see what you're looking for? See all car rentals in Santiago Island [View all cars](https://expedia.com/carsearch?paandi=true&fdrp=1&styp=2&dagv=1&subm=1&locn=Santiago%20Island,%20Gal%C3%A1pagos,%20Ecuador&dpln=6336381&date1=2/14/2026&date2=2/16/2026&crfrr=defaultFlex&SearchType=Place&selCC=[%22midsize%22]) ## FAQs for Midsize Car Rentals in Santiago Island ### Where can I get Midsize car rentals in Santiago Island There are several locations and suppliers offering Midsize car rentals throughout Santiago Island, Galápagos. Click around to view the options in the area, compare and find the best deal that’s most convenient for you on Expedia.com. ### How do I get the best deals on Midsize car rentals in Santiago Island with Expedia.com? You can compare the top deals from providers in the area on Expedia.com. Prices may vary depending on travel dates, car type, and pick-up location. Head over to the main [car rentals in Santiago Island](https://www.expedia.com/Car-Rentals-In-Santiago Island.d6336381.Car-Rental-Guide) page to see all available offers and car types. ### What is the cancellation policy for car rentals in Santiago Island? Cancellation policies differ by deal type. There are lots of deals that are free to cancel within your cancellation deadline. A pre-paid Midsize car rental in Santiago Island will most likely be non-refundable. We recommend filtering by “free cancellation” to see the most flexible options. ### Why should I book my car rental on Expedia.com? Expedia.com is your one-stop-shop for all your travel needs. You’ll see a large selection and some of the best deals to find your Midsize rental in Santiago Island. Whether you’re traveling for business or pleasure, whether you’re looking for a short or [long term car rental](https://www.expedia.com/lp/b/car-rental/long-term) we’ve got you covered. Book your car with flights or [hotels in Santiago Island](https://www.expedia.com/Santiago Island-Hotels.d6336381.Travel-Guide-Hotels). We’ll bundle them into a [vacation package in Santiago Island](https://www.expedia.com/Santiago Island.d6336381.Destination-Travel-Guides) with even more discounts. ## Midsize Car Rental Information | Car type: | Midsize | | ------------------------------------------------- | ------------------------------------------------------------------------------------------------------- | | Price: | | | From the airport to your hotel: | [Airport Transportation](https://www.expedia.com/ground-transfers?rfrr=car.table.AirportTransportation) | | From popular domestic and international airports: | [Airport Car Rentals](https://www.expedia.com/lp/b/car-rental/airport) | ## Frequently asked questions ### How can I get a cheap midsize car rental in Santiago Island with Expedia? ### How much does it cost to rent a midsize car in Santiago Island? ### How old do you have to be to rent a midsize car in Santiago Island? ### Why should I rent a midsize car in Santiago Island? ### How can I rent a midsize car in Santiago Island? ### Why should I rent a midsize car through Expedia? ### What happens if I need to cancel my Santiago Island midsize car rental reservation? ## Explore a world of travel with Expedia - 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