Find hotels near OSF St. Mary Medical Center, Galesburg from $70

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Compare 62 hotels close to OSF St. Mary Medical Center with room rates, reviews, and availability. Most hotels are fully refundable.

Fairfield Inn & Suites Galesburg

2.5 star property
1.6 mi from OSF St. Mary Medical Center
8.6 out of 10, Excellent, (393)
"Super clean and attractive hotel with a full hot breakfast. "
United States
Kristin
$110 nightly
The price is $128
Dec 14 - Dec 15
Total with taxes and fees
Fairfield Inn & Suites Galesburg

Quality Inn Galesburg near US Highway 34 and I-74

2.5 star property
1.6 mi from OSF St. Mary Medical Center
7.2 out of 10, Good, (405)
"Clean and had a nice breakfast with los of options. Would stay again. "
United States
Cynthia
$72 nightly
The price is $84
Dec 27 - Dec 28
Total with taxes and fees
Quality Inn Galesburg near US Highway 34 and I-74

AmericInn by Wyndham Galesburg

2.5 star property
1.8 mi from OSF St. Mary Medical Center
8.2 out of 10, Very Good, (1000)
"Clean and nice location"
United States
Nancy
$71 nightly
The price is $82
Dec 7 - Dec 8
Total with taxes and fees
AmericInn by Wyndham Galesburg

Galesburg Extended Stay

2.0 star property
3.4 mi from OSF St. Mary Medical Center
5.0 out of 10, (14)
"Place was a dump"
United States
Kaiden
$65 nightly
The price is $76
Dec 5 - Dec 6
Total with taxes and fees
Galesburg Extended Stay

Holiday Inn Express & Suites Galesburg by IHG

2.5 star property
3 mi from OSF St. Mary Medical Center
9.4 out of 10, Exceptional, (440)
"Friendly staff, comfortable room, loved the free breakfast. "
United States
Larry
$147 nightly
The price is $172
Jan 1 - Jan 2, 2026
Total with taxes and fees
Holiday Inn Express & Suites Galesburg by IHG

Baymont by Wyndham Galesburg

2.5 star property
3.1 mi from OSF St. Mary Medical Center
8.2 out of 10, Very Good, (1000)
"We stay here a few times a year never disapointed. "
United States
Karl
$73 nightly
The price is $85
Jan 4 - Jan 5, 2026
Total with taxes and fees
Baymont by Wyndham Galesburg

Best Western Prairie Inn & Conference Center

3.0 star property
3.4 mi from OSF St. Mary Medical Center
7.8 out of 10, Good, (746)
"Decent hotel Rooms are clean Wish there was some closer restaurant options"
Canada
Jonathan
$78 nightly
The price is $91
Dec 23 - Dec 24
Total with taxes and fees
Best Western Prairie Inn & Conference Center

Super 8 by Wyndham Galesburg

2.0 star property
5.7 mi from OSF St. Mary Medical Center
7.6 out of 10, Good, (494)
"Our room was very clean, the bed comfortable, and the shower very nice. No housekeeping for our three-night stay, but a nice room."
United States
Eldon and Peggy
$63 nightly
The price is $70
Dec 10 - Dec 11
Total with taxes and fees
Super 8 by Wyndham Galesburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

What's the area like around OSF St. Mary Medical Center?
OSF St. Mary Medical Center is located in Galesburg. Travelers like the surrounding area for its shopping. You'll find 16 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to OSF St. Mary Medical Center?
Baymont by Wyndham Galesburg is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located 3.1 mi (4.9 km) from OSF St. Mary Medical Center. Other good choices within 5 miles include AmericInn by Wyndham Galesburg and Fairfield Inn & Suites Galesburg.
How many hotels will I find near OSF St. Mary Medical Center?
Expedia has 16 hotels and other accommodations a few miles from OSF St. Mary Medical Center.
If I need to cancel the hotel reservation for my stay near OSF St. Mary Medical Center, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to view the best deals near OSF St. Mary Medical Center.
Where can I learn more about changing or cancelling my trip in the area near OSF St. Mary Medical Center?
For additional details about changing or cancelling your stay near OSF St. Mary Medical Center, click here.
What can I see and do near OSF St. Mary Medical Center?
You might spend a leisurely day outdoors at Lakeside Water Park and Martin Park. Create some family memories at Discovery Depot Children's Museum and Galesburg Railroad Museum. Lake Storey, Carl Sandburg College, and Knox College are a few additional nearby sights.