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Prairie Home Vacation Rentals

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Check prices for these dates

In two weeks
Nov 13 - Nov 15
In two months
Dec 25 - Dec 27
In three months
Jan 22 - Jan 24
In four months
Feb 19 - Feb 21

Our top choices for Prairie Home vacation rentals

An open refrigerator with multiple shelves and a water dispenser.

1. 3 Bed 1.5 Bath Pet Friendly Apt

3 Bed 1.5 Bath Pet Friendly Apt
Columbia
10.0 out of 10, Exceptional, (13 reviews)
"Property was clean and comfortable and host was attentive."
United States
Stephanie A.
$181 nightly
The price is $181
Nov 1 - Nov 2
Total with taxes and fees
3 Bed 1.5 Bath Pet Friendly Apt
An old brick building with a sign reading "Lupus General Store."

2. Quiet Riverfront Cottage on Missouri River

Quiet Riverfront Cottage on Missouri River
Jamestown
8.8 out of 10, Excellent, (17 reviews)
"It is a beautiful, quiet country setting and you can walk to the riverbank from the place."
United States
Patti M.
$189 nightly
The price is $201
Nov 9 - Nov 10
Total with taxes and fees
Quiet Riverfront Cottage on Missouri River
A staircase with wooden steps and white railings, leading to a second floor.

3. Restored 2-bedroom cottage in beautiful California, MO

Restored 2-bedroom cottage in beautiful California, MO
California
10.0 out of 10, Exceptional, (1 review)
"The house was warm & cozy, bed super comfortable. Very cute historic home, we enjoyed our stay!"
United States
Shelley F.
$200 nightly
The price is $216
Nov 1 - Nov 2
Total with taxes and fees
Restored 2-bedroom cottage in beautiful California, MO
A bedroom with a fireplace, a TV mounted above it, a bed with a blue blanket, and a blue armchair with a patterned pillow.

4. Historic Cozy Apartment 1 Bedroom In Peaceful Boonville

Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
Boonville
9.6 out of 10, Exceptional, (26 reviews)
"Apartment was clean and adequate for our stay. A bit tight for four people but would be fine for a couple."
United States
Bradley O.
$180 nightly
The price is $194
Nov 2 - Nov 3
Total with taxes and fees
Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
A two-story brick building with a sign reading "Lupus General Store".

5. Step Back in Time Near The Missouri River

Step Back in Time Near The Missouri River
Jamestown
9.8 out of 10, Exceptional, (24 reviews)
"Perfect spot!"
United States
Nicole
$286 nightly
The price is $303
Nov 9 - Nov 10
Total with taxes and fees
Step Back in Time Near The Missouri River
A narrow hallway with a wooden bench on the right, a rocking chair in the center, and a bed at the end.

6. The Katy Caboose in Hartsburg

The Katy Caboose in Hartsburg
Hartsburg
10.0 out of 10, Exceptional, (3 reviews)
"We had an amazing time on the trip! The host was amazing with communication and answering any questions that came up. The caboose itself was super comfortable and spacious. We really appreciated the pet friendly aspect and our dog had a wonderful time on the property!"
United States
Veronica R.
$187 nightly
The price is $198
Nov 1 - Nov 2
Total with taxes and fees
The Katy Caboose in Hartsburg
A single-story house with a garage, a front porch with red chairs, and a well-maintained lawn.

7. Relax Enjoy Mid-Missouri with Fenced in Back Yard

Relax Enjoy Mid-Missouri with Fenced in Back Yard
Boonville
10.0 out of 10, Exceptional, (19 reviews)
"It was a nice place to stay.m"
United States
Dallas A.
$349 nightly
The price is $358
Nov 13 - Nov 14
Total with taxes and fees
Relax Enjoy Mid-Missouri with Fenced in Back Yard
A kitchen counter with a framed Valentine's Day card, a bottle of wine, and chocolate gifts.

8. Full House Just Steps Away from Missouri River, Katy Trail, Shopping & More!

Full House Just Steps Away from Missouri River, Katy Trail, Shopping & More!
Boonville
9.6 out of 10, Exceptional, (116 reviews)
"Convenient location, prompt communication, all the comforts of home. Great beds. Lots of space. Better than a hotel in many ways."
United States
Susan
Full House Just Steps Away from Missouri River, Katy Trail, Shopping & More!
A kitchen with dark cabinets, a stainless steel refrigerator, a microwave, and a dishwasher.

9. ~A Home Away From Home~Sleeps 8~

~A Home Away From Home~Sleeps 8~
Columbia
9.6 out of 10, Exceptional, (8 reviews)
"VRBO was exactly as described. Check in was super easy, and communication with the host was seamless."
United States
Bryon L.
$268 nightly
The price is $283
Nov 1 - Nov 2
Total with taxes and fees
~A Home Away From Home~Sleeps 8~
A white entertainment center with a flat-screen TV, decorative items, and a remote control.

10. 10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!

10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!
Columbia
9.6 out of 10, Exceptional, (52 reviews)
"Very comfortable and friendly host!"
United States
Troy V.
$177 nightly
The price is $190
Nov 1 - Nov 2
Total with taxes and fees
10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!
A spacious living area with a sofa, a patterned ottoman, and a fireplace.

11. Whispering Woods Hideaway ~ Large Home ~ 85 in TV

Whispering Woods Hideaway ~ Large Home ~ 85 in TV
Columbia
9.8 out of 10, Exceptional, (6 reviews)
"Clean house. Very responsive"
United States
Gary B.
$453 nightly
The price is $476
Oct 31 - Nov 1
Total with taxes and fees
Whispering Woods Hideaway ~ Large Home ~ 85 in TV
A hallway with a blue-lit wall-mounted light fixture, a door leading to another room, and a wooden table in the foreground.

12. Como's Finest- A Home Away From Home- Sleeps 10

Como's Finest- A Home Away From Home- Sleeps 10
Columbia
9.4 out of 10, Exceptional, (8 reviews)
"Great place for a weekend trip"
United States
Brandon W.
$271 nightly
The price is $285
Nov 1 - Nov 2
Total with taxes and fees
Como's Finest- A Home Away From Home- Sleeps 10
A hallway with a geometric black and white tiled floor, a white door at the end, and a small bench with a plant beside it.

13. Relaxing Three Bedroom Getaway in Boonville

Relaxing Three Bedroom Getaway in Boonville
Boonville
9.6 out of 10, Exceptional, (38 reviews)
"Great host who cares about the guests"
United States
Trevor M.
$223 nightly
The price is $241
Nov 9 - Nov 10
Total with taxes and fees
Relaxing Three Bedroom Getaway in Boonville
An outdoor patio with a sofa set, a coffee table, and a patterned rug.

14. Relax Enjoy Country Living-Hot Tub & Seasonal Pool

Relax Enjoy Country Living-Hot Tub & Seasonal Pool
New Franklin
10.0 out of 10, Exceptional, (12 reviews)
"We really enjoyed our stay. It is such a tranquil property and Jill was an amazing host. "
United States
Mike P.
$397 nightly
The price is $410
Nov 22 - Nov 23
Total with taxes and fees
Relax Enjoy Country Living-Hot Tub & Seasonal Pool
A stone-walled entrance with a white door, a number '3' sign, and a small outdoor light fixture.

15. Super Close to Mizzou Condo 2 Bed 1 Bath

Super Close to Mizzou Condo 2 Bed 1 Bath
Columbia
10.0 out of 10, Exceptional, (19 reviews)
"The stay was great. Clean, quiet, comfortable, well equipped. Also very convenient location"
United States
William
$200 nightly
The price is $200
Nov 8 - Nov 9
Total with taxes and fees
Super Close to Mizzou Condo 2 Bed 1 Bath
A modern kitchen with dark cabinets, stainless steel appliances, and a wooden dining table.

16. 3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena

3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
Columbia
9.6 out of 10, Exceptional, (16 reviews)
"Great place to stay! "
United States
Stacy B.
$324 nightly
The price is $341
Nov 1 - Nov 2
Total with taxes and fees
3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
Interior

17. Spacious Boonville Retreat with Full Kitchen and Laundry

Spacious Boonville Retreat with Full Kitchen and Laundry
Boonville
$248 nightly
The price is $269
Nov 1 - Nov 2
Total with taxes and fees
Spacious Boonville Retreat with Full Kitchen and Laundry
A hallway with a dining area, a door, a wall-mounted sign, a potted plant, and a small table with a lamp.

18. Comfy Home~Teal Feel~ Sleeps 8

Comfy Home~Teal Feel~ Sleeps 8
Columbia
8.4 out of 10, Very good, (8 reviews)
"Went there for work. Great place to stay. Loved the beds, very comfortable. I will stay there again when I come back."
United States
Kevin G.
$234 nightly
The price is $246
Nov 9 - Nov 10
Total with taxes and fees
Comfy Home~Teal Feel~ Sleeps 8
An outdoor patio area with wicker furniture, a fire pit, and a covered seating area.

19. Accessible Studio Suite w/ Breakfast Included, Near Mizzou

Accessible Studio Suite w/ Breakfast Included, Near Mizzou
Columbia
$166 nightly
The price is $185
Nov 8 - Nov 9
Total with taxes and fees
Accessible Studio Suite w/ Breakfast Included, Near Mizzou
A compact kitchen with a refrigerator, sink, and stove, a dining table with chairs, and a view through a sliding glass door.

20. Cozy, well appointed 3-bedroom, 1.5-bath house 10 min from Mizzou

Cozy, well appointed 3-bedroom, 1.5-bath house 10 min from Mizzou
Columbia
10.0 out of 10, Exceptional, (5 reviews)
"The space was VERY clean. We walked about in bare feet, and our feet stayed clean. It really helped us to relax and enjoy the place. The kitchen was well stocked. We cooked a few times, and found all the utensils/pots and pans we needed. Beds were quite comfortable. While we could not walk to any thing, it was a very short drive to anything we wanted or needed (by short we mean less than 15 minutes). The neighborhood was quiet at night (even though it was during the 4th of July). The...
United States
Matt K.
$291 nightly
The price is $311
Nov 8 - Nov 9
Total with taxes and fees
Cozy, well appointed 3-bedroom, 1.5-bath house 10 min from Mizzou
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Prairie Home Hotel Reviews

Quality Inn & Suites Columbia I-70

Quality Inn & Suites Columbia I-70

8/10 Good
"They took care of my son and watched after him."
McHale 1-night trip
Posted 1 hour ago
Quality Inn & Suites Columbia I-70

Find out more about Prairie Home

Everything you need to know about Prairie Home vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Prairie Home vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Prairie Home vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Prairie Home vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Prairie Home. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Prairie Home in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $193 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Prairie Home rentals

At Expedia, we put the best Prairie Home vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Prairie Home rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Prairie Home vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Prairie Home. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Prairie Home?

Yes, you can find vacation rentals close to well known attractions in Prairie Home, or you can select a secluded option if you're looking for relaxation.

What's the top vacation rental that Prairie Home has to offer?

The Stone & Bridge: Close to MKT Trail & Dog Park, Dining, Groceries & I-70: This vacation home rental near Prairie Home offers a patio, a barbecue grill, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What can I see and do in Prairie Home?

While exploring the area, visit family-friendly sights like Warm Springs Ranch, or get outside and enjoy nature at Shelter Gardens. Isle of Capri Casino and Rock Bridge Memorial State Park are a couple of places you'll find in the larger area.

What are vacation rentals like in Prairie Home?

Vacation rentals are private properties you can stay in for a few days or a quick weekend in Prairie Home. Vacation rentals feature amenities such as hot tubs, fire pits, and patios so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can provide a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for a small group gathering.