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Prairie Home Vacation Rentals

Check prices for these dates

In two weeks
Sep 11 - Sep 13
In two months
Oct 23 - Oct 25
In three months
Nov 20 - Nov 22
In four months
Dec 18 - Dec 20

Our top choices for Prairie Home vacation rentals

An open refrigerator with multiple shelves and a water dispenser.

1. 3 Bed 1.5 Bath Pet Friendly Apt

3 Bed 1.5 Bath Pet Friendly Apt
Columbia
10.0 out of 10, Exceptional, (11 reviews)
"This was a perfect place to stay for our family while in town for a swim meet. Great communication from the owner. Clean and plenty of space for all of us! This is a great property!"
United States
Lacey S.
$206 nightly
The price is $206
Sep 1 - Sep 2
Total with taxes and fees
3 Bed 1.5 Bath Pet Friendly Apt
An old brick building with a sign reading "Lupus General Store."

2. Quiet Riverfront Cottage on Missouri River

Quiet Riverfront Cottage on Missouri River
Jamestown
9.2 out of 10, Wonderful, (15 reviews)
"The stay was a wonderful "
United States
PAUL S.
$173 nightly
The price is $184
Aug 26 - Aug 27
Total with taxes and fees
Quiet Riverfront Cottage on Missouri River
A two-story brick building with a sign reading "Lupus General Store".

3. Step Back in Time Near The Missouri River

Step Back in Time Near The Missouri River
Jamestown
9.8 out of 10, Exceptional, (23 reviews)
"Perfect spot!"
United States
Nicole
$263 nightly
The price is $279
Aug 26 - Aug 27
Total with taxes and fees
Step Back in Time Near The Missouri River
A narrow hallway with a wooden bench on the right, a rocking chair in the center, and a bed at the end.

4. The Katy Caboose in Hartsburg

The Katy Caboose in Hartsburg
Hartsburg
10.0 out of 10, Exceptional, (2 reviews)
"Fun little place right on the Katy Trail. Hosts were very responsive, and we enjoyed our stay. Know two things: 1) bathroom is in a separate building next door; 2) food choices, especially before the weekend, are almost non existent. But that's not the owners fault-they provided a great place to stay and we will do so again next time we are on the Katy. Thanks!"
United States
Mike G.
$198 nightly
The price is $209
Aug 30 - Aug 31
Total with taxes and fees
The Katy Caboose in Hartsburg
A kitchen with dark cabinets, a stainless steel refrigerator, a microwave, and a dishwasher.

5. ~A Home Away From Home~Sleeps 8~

~A Home Away From Home~Sleeps 8~
Columbia
9.6 out of 10, Exceptional, (8 reviews)
"VRBO was exactly as described. Check in was super easy, and communication with the host was seamless."
United States
Bryon L.
$271 nightly
The price is $286
Aug 29 - Aug 30
Total with taxes and fees
~A Home Away From Home~Sleeps 8~
A staircase with wooden steps and white railings, leading to a second floor.

6. Restored 2-bedroom cottage in beautiful California, MO

Restored 2-bedroom cottage in beautiful California, MO
California
10.0 out of 10, Exceptional, (1 review)
"The house was warm & cozy, bed super comfortable. Very cute historic home, we enjoyed our stay!"
United States
Shelley F.
$227 nightly
The price is $244
Aug 26 - Aug 27
Total with taxes and fees
Restored 2-bedroom cottage in beautiful California, MO
A bedroom with a fireplace, a TV mounted above it, a bed with a blue blanket, and a blue armchair with a patterned pillow.

7. Historic Cozy Apartment 1 Bedroom In Peaceful Boonville

Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
Boonville
9.6 out of 10, Exceptional, (24 reviews)
"Everything was clean and cozy!"
United States
Rhonda M.
$191 nightly
The price is $205
Sep 21 - Sep 22
Total with taxes and fees
Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
A stone-walled entrance with a white door, a number '3' sign, and a small outdoor light fixture.

8. Super Close to Mizzou Condo 2 Bed 1 Bath

Super Close to Mizzou Condo 2 Bed 1 Bath
Columbia
10.0 out of 10, Exceptional, (14 reviews)
"The stay was great. Clean, quiet, comfortable, well equipped. Also very convenient location"
United States
William
$191 nightly
The price is $191
Aug 31 - Sep 1
Total with taxes and fees
Super Close to Mizzou Condo 2 Bed 1 Bath
A white entertainment center with a flat-screen TV, decorative items, and a remote control.

9. 10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!

10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!
Columbia
9.8 out of 10, Exceptional, (47 reviews)
"Very comfortable and friendly host!"
United States
Troy V.
$174 nightly
The price is $186
Aug 26 - Aug 27
Total with taxes and fees
10min from MIZZOU/Univ Hospital/downtown! Family sized, CLEAN! Short term avail!
A hallway with a blue-lit wall-mounted light fixture, a door leading to another room, and a wooden table in the foreground.

10. Como's Finest- A Home Away From Home- Sleeps 10

Como's Finest- A Home Away From Home- Sleeps 10
Columbia
9.2 out of 10, Wonderful, (7 reviews)
"Great place for a weekend trip"
United States
Brandon W.
$277 nightly
The price is $291
Sep 1 - Sep 2
Total with taxes and fees
Como's Finest- A Home Away From Home- Sleeps 10
A living room with a flat-screen TV displaying a streaming service interface, a dark-colored sofa with a knitted throw pillow, a coffee table, and a rug.

11. Heying Essentials

Heying Essentials
Columbia
8.0 out of 10, Very Good, (2 reviews)
"House was clean and host was prompt and helpful. I recommend this property."
United States
Damian G.
$257 nightly
The price is $270
Aug 28 - Aug 29
Total with taxes and fees
Heying Essentials
A modern kitchen with dark cabinets, stainless steel appliances, and a wooden dining table.

12. 3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena

3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
Columbia
9.6 out of 10, Exceptional, (15 reviews)
"Great place to stay! "
United States
Stacy B.
$323 nightly
The price is $340
Aug 27 - Aug 28
Total with taxes and fees
3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
A cozy bedroom with a bed, a wooden table, a chair, and a staircase.

13. Cozy cabin getaway with hot-tub under stars!

Cozy cabin getaway with hot-tub under stars!
Ashland
9.6 out of 10, Exceptional, (30 reviews)
"This is our second time staying here and we love it. Such a peaceful relaxing place."
United States
Ryan L.
$240 nightly
The price is $253
Aug 26 - Aug 27
Total with taxes and fees
Cozy cabin getaway with hot-tub under stars!
A hallway with a dining area, a door, a wall-mounted sign, a potted plant, and a small table with a lamp.

14. Comfy Home~Teal Feel~ Sleeps 8

Comfy Home~Teal Feel~ Sleeps 8
Columbia
7.6 out of 10, Good, (5 reviews)
"Host was great. Communicated was awesome"
United States
marcus b.
$235 nightly
The price is $247
Aug 26 - Aug 27
Total with taxes and fees
Comfy Home~Teal Feel~ Sleeps 8
A spacious living room with a brown sofa, wooden chairs, a coffee table, and a ceiling fan.

15. Quaint cottage w/ direct access to Katy Trail!

Quaint cottage w/ direct access to Katy Trail!
Hartsburg
$211 nightly
The price is $223
Aug 30 - Aug 31
Total with taxes and fees
Quaint cottage w/ direct access to Katy Trail!
A kitchen counter with a framed Valentine's Day card, a bottle of wine, and chocolates.

16. Full House Just Steps Away from Missouri River, Katy Trail, Shopping & More!

Full House Just Steps Away from Missouri River, Katy Trail, Shopping & More!
Boonville
9.8 out of 10, Exceptional, (109 reviews)
"The owner was very responsive with questions, let us know about a problem that came up and when it was fixed. House was very well stocked with everything that we could have wanted to make ourselves at home. Very roomy. I would highly recommend this place and we are hoping to return in the future."
United States
Michelle
$200 nightly
The price is $223
Aug 30 - Aug 31
Total with taxes and fees
Full House Just Steps Away from Missouri River, Katy Trail, Shopping & More!
A room with three framed pictures on the wall, a radiator, a patterned sofa, and a window with blinds.

17. Carriage House by CMU - Lower Condo - Kitchen, King Bed, 70" TV Fast WiFi & AC

Carriage House by CMU - Lower Condo - Kitchen, King Bed, 70" TV Fast WiFi & AC
Fayette
9.8 out of 10, Exceptional, (28 reviews)
"Love the location close to CMUComfortable surrounds and this is always my first choice when I come to visit my daughter!"
United States
Ann B.
$214 nightly
The price is $230
Aug 26 - Aug 27
Total with taxes and fees
Carriage House by CMU - Lower Condo - Kitchen, King Bed, 70" TV Fast WiFi & AC

18. Relax Enjoy Country Living-Hot Tub & Seasonal Pool

Relax Enjoy Country Living-Hot Tub & Seasonal Pool
New Franklin
10.0 out of 10, Exceptional, (11 reviews)
"We really enjoyed our stay. It is such a tranquil property and Jill was an amazing host. "
United States
Mike P.
$393 nightly
The price is $405
Aug 30 - Aug 31
Total with taxes and fees
Relax Enjoy Country Living-Hot Tub & Seasonal Pool
A spacious living area with a sofa, a patterned ottoman, and a fireplace.

19. Whispering Woods Hideaway ~ Large Home ~ 85 in TV

Whispering Woods Hideaway ~ Large Home ~ 85 in TV
Columbia
10.0 out of 10, Exceptional, (4 reviews)
"Clean house. Very responsive"
United States
Gary B.
$453 nightly
The price is $476
Aug 30 - Aug 31
Total with taxes and fees
Whispering Woods Hideaway ~ Large Home ~ 85 in TV

20. Relax Enjoy Mid-Missouri with Fenced in Back Yard

Relax Enjoy Mid-Missouri with Fenced in Back Yard
Boonville
10.0 out of 10, Exceptional, (16 reviews)
"It was a nice place to stay.m"
United States
Dallas A.
$368 nightly
The price is $375
Aug 26 - Aug 27
Total with taxes and fees
Relax Enjoy Mid-Missouri with Fenced in Back Yard
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Prairie Home Hotel Reviews

The Broadway Columbia - a DoubleTree by Hilton

The Broadway Columbia - a DoubleTree by Hilton

10/10 Excellent
"Lovely, clean place!!"
Courtney 1-night trip
Posted 12 hours ago
The Broadway Columbia - a DoubleTree by Hilton

Find out more about Prairie Home

Everything you need to know about Prairie Home vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Prairie Home vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Prairie Home vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Prairie Home vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Prairie Home. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Prairie Home in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $157 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Prairie Home rentals

At Expedia, we put the best Prairie Home vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Prairie Home rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Prairie Home vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Prairie Home. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Can I find a vacation rental in Prairie Home?

Yes, you can find vacation rentals close to well known attractions in Prairie Home, or you can select a secluded option if you're looking for relaxation.

What's the top vacation rental that Prairie Home has to offer?

Quiet 3 min to campus! Back porch/decks & firepit, w/ 5 car parking. YourPlace!: This vacation home rental near Prairie Home offers a patio, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family.

What can I see and do in Prairie Home?

While exploring the area, visit family-friendly sights like Warm Springs Ranch, or get outside and enjoy nature at Shelter Gardens. Isle of Capri Casino and Rock Bridge Memorial State Park are a couple of places you'll find in the larger area.

What are vacation rentals like in Prairie Home?

Vacation rentals are private properties you can stay in for a few days or a quick weekend in Prairie Home. Vacation rentals feature amenities such as hot tubs, fire pits, and patios so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can provide a sense of seclusion away from public hotel elevators and lobbies packed with people while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for a small group gathering.