A coastal landscape with clear turquoise waters, rocky hills, and a distant mountain range.
Photo by Erica Previtali
Open Photo by Erica Previtali

Samos Prefecture Vacations from $954

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Your Samos Prefecture Vacation

With a Samos Prefecture vacation package, you can forget about the hassle of planning and put all your energy into experiencing all this lively destination has on offer. Not sure where to stay? Potokaki is one of the leading cities to visit during your trip to Samos Prefecture. Expedia is a one-stop shop for planning your Samos Prefecture vacation. From flights and hotels, to rental cars and more, we know how to create a travel experience like no other.

The Latest Samos Prefecture Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • A narrow cobblestone path leading to a patio area with outdoor seating and potted plants.
    Dec 11 - Dec 17

    Anthemis Hotel + Flight

    Ikaria
    5 nights
    2.0 star property
    8.8/10 - Excellent (39 reviews)
    "Breakfast was great value. Host was very accommodating."
    Reviewed October 3, 2026
    Roundtrip • Houston (HOU) - Samos (SMI)
    IAH - ATH • 1 stop ATH - IAH • 2 stops
    $1,007
    $954
    per traveler
    found 23 hours ago
    Anthemis Hotel

Discover the most popular places to visit in Samos Prefecture

A coastal village with colorful buildings, boats docked in the water, and mountains in the background.

Kokkari Beach

8.8/10 (5 reviews)
Why not spend a lazy afternoon at Kokkari Beach during your trip to Kokkari? While you're in the area, stroll along the beaches.
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Samos Prefecture Hotel Deals

A table with a smartphone, two glasses of water, and a bottle with a lime slice.

Erato by Samian Mare

Erato by Samian Mare
4.0 star property
8 mi from Samos Prefecture
9.0 out of 10, Wonderful, (20 reviews)
"Everything was perfect, Katerina at reception was spot on and wonderful :-) "
$73 nightly
The price is $83
Dec 6 - Dec 7
Total with taxes and fees
Erato by Samian Mare
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in Samos Prefecture
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.