San Luis Vacation Rentals

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Check prices for these dates

In two weeks
Dec 26 - Dec 28
In two months
Feb 6 - Feb 8
In three months
Mar 6 - Mar 8
In four months
Apr 3 - Apr 5

Our top choices for San Luis vacation rentals

Fridge, microwave, oven, stovetop
Charming 2-bedroom townhome with WiFi, AC in East San Luis, AZ.

Vacation Home in San Luis

Charming 2-bedroom townhome with WiFi, AC in East San Luis, AZ.
10.0 out of 10, Exceptional, (3)
"I had a great stay! The home was very nice, clean, and quiet—just what I was looking for. Everything was well-kept and comfortable, making it easy to relax. The neighborhood felt peaceful and safe, and I really appreciated how tidy the space was. I would definitely stay here again and recommend it to anyone looking for a calm and pleasant place to stay."
United States
Alexandra C.
$160 nightly
The price is $175
Dec 31 - Jan 1, 2026
Total with taxes and fees
Charming 2-bedroom townhome with WiFi, AC in East San Luis, AZ.
Terrace/patio
One-bedroom casita.

Apartment in Yuma

One-bedroom casita.
$28 nightly
The price is $29
Jan 3 - Jan 4, 2026
Total with taxes and fees
One-bedroom casita.
Pool
The Yellow Bench at Yuma

Cottage in Yuma

The Yellow Bench at Yuma
2.0 star property
10.0 out of 10, Exceptional, (1)
"Nice space. Clean and convenient to MCAS and shopping. Very easy to book and access. "
United States
Marshall P.
$143 nightly
The price is $156
Dec 14 - Dec 15
Total with taxes and fees
The Yellow Bench at Yuma
Interior
Yuma Townhouse - Centrally Located!

Vacation Home in Yuma

Yuma Townhouse - Centrally Located!
10.0 out of 10, Exceptional, (77)
"This is a great place to stay in Yuma AZ. The house is clean and comfortable in a great location. Check-in was easy and I highly recommend!"
United States
Marisol F.
$214 nightly
The price is $234
Dec 13 - Dec 14
Total with taxes and fees
Yuma Townhouse - Centrally Located!
Terrace/patio
private entrance bedroom with own bathroom

Apartment in Yuma

private entrance bedroom with own bathroom
$80 nightly
The price is $86
Jan 1 - Jan 2, 2026
Total with taxes and fees
private entrance bedroom with own bathroom
Property grounds
Stylish Downtown Yuma Retreat with River Vibes

Apartment in Downtown Yuma

Stylish Downtown Yuma Retreat with River Vibes
2.0 star property
10.0 out of 10, Exceptional, (2)
"For our age (80) the stairs were some what of an issue. However everything else was great."
United States
Larry Glen A.
$149 nightly
The price is $163
Dec 15 - Dec 16
Total with taxes and fees
Stylish Downtown Yuma Retreat with River Vibes
Property grounds
One story fully furnished townhouse

Vacation Home in Yuma

One story fully furnished townhouse
9.4 out of 10, Exceptional, (53)
"We enjoyed our stay in Yuma very much! Great house and location. "
Canada
Angela N.
$197 nightly
The price is $215
Dec 13 - Dec 14
Total with taxes and fees
One story fully furnished townhouse
Fridge, microwave, oven, stovetop
Cozy studio in Yuma's Century Heights historic district!

Apartment in Yuma Townsite

Cozy studio in Yuma's Century Heights historic district!
10.0 out of 10, Exceptional, (5)
"Great location to old town Yuma, shopping and restaurants. We enjoyed our stay and were very comfortable."
United States
jayne H.
$130 nightly
The price is $141
Dec 13 - Dec 14
Total with taxes and fees
Cozy studio in Yuma's Century Heights historic district!
Fridge, microwave, oven, stovetop
Guest House in the outskirts, Ranch living

Apartment in Somerton

Guest House in the outskirts, Ranch living
9.0 out of 10, Wonderful, (2)
"Great stay for a single night. Very responsive host. Would stay again."
United States
Sharla M.
$92 nightly
The price is $97
Dec 14 - Dec 15
Total with taxes and fees
Guest House in the outskirts, Ranch living
Property grounds
Pet-Friendly, Charming bungalow with WiFi and AC in sunny Yuma

Vacation Home in Yuma Townsite

Pet-Friendly, Charming bungalow with WiFi and AC in sunny Yuma
10.0 out of 10, Exceptional, (2)
"I was in town for an assembly, and this bungalow felt like home! So much space to chill out! And they left snacks! And cool cool water! Thank you so much!"
United States
Jessica H.
$142 nightly
The price is $155
Dec 28 - Dec 29
Total with taxes and fees
Pet-Friendly, Charming bungalow with WiFi and AC in sunny Yuma
Interior
Centrally located older 4-bedroom house in lovely Yuma

Vacation Home in Yuma

Centrally located older 4-bedroom house in lovely Yuma
8.8 out of 10, Excellent, (8)
"Nice property and the host was very nice and communicated well. "
United States
Shannon O.
$165 nightly
The price is $180
Dec 13 - Dec 14
Total with taxes and fees
Centrally located older 4-bedroom house in lovely Yuma
Terrace/patio
Cozy 2BDx2BA townhome in Yuma, close to I-8

Vacation Home in Yuma

Cozy 2BDx2BA townhome in Yuma, close to I-8
2.0 star property
$187 nightly
The price is $204
Dec 13 - Dec 14
Total with taxes and fees
Cozy 2BDx2BA townhome in Yuma, close to I-8
Fridge, microwave, oven, stovetop
Vista del Valle

Vacation Home in Vista Del Valle

Vista del Valle
10.0 out of 10, Exceptional, (140)
"Smooth lodging with no hassle. "
United States
BoEldridge M.
$214 nightly
The price is $234
Dec 20 - Dec 21
Total with taxes and fees
Vista del Valle
Fridge, microwave, oven, stovetop
Cozy condo in Yuma!

Vacation Home in Yuma

Cozy condo in Yuma!
9.0 out of 10, Wonderful, (6)
"This house was clean, very comfortable, close to everything. We really enjoyed staying there. Only regret we didn’t get to stay long enough. My grandson says it’s a 500 out of 100."
United States
Alton K.
$182 nightly
The price is $199
Dec 14 - Dec 15
Total with taxes and fees
Cozy condo in Yuma!
Outdoor pool
Home away from home-Quiet cozy casita

Vacation Home in Palo Verde

Home away from home-Quiet cozy casita
9.6 out of 10, Exceptional, (10)
"Our family enjoyed our time at this property. Very cozy and had everything we needed. Host even ensured we had enough towels and was very accommodating. Neighborhood was great and felt very safe to take a run."
United States
Christopher H.
$395 nightly
The price is $431
Dec 20 - Dec 21
Total with taxes and fees
Home away from home-Quiet cozy casita
Apartment (3 Bedrooms) | Interior
Close to Golf! Snowbird Retreat w/ Pool in Yuma

Apartment in Yuma Corona

Close to Golf! Snowbird Retreat w/ Pool in Yuma
3.0 star property
$394 nightly
The price is $435
Dec 13 - Dec 14
Total with taxes and fees
Close to Golf! Snowbird Retreat w/ Pool in Yuma
Private kitchen
Entire home in Yuma, Arizona

Vacation Home in Yuma

Entire home in Yuma, Arizona
2.0 star property
$297 nightly
The price is $324
Dec 27 - Dec 28
Total with taxes and fees
Entire home in Yuma, Arizona
Property grounds
Modern Desert Oasis Studio in Historic Downtown Yuma

Apartment in Downtown Yuma

Modern Desert Oasis Studio in Historic Downtown Yuma
2.0 star property
10.0 out of 10, Exceptional, (9)
"The property was exactly what I was looking for. Small, but felt spacious and had all of the amenities I needed when spending a week in Yuma for work. It’s quiet, parking is easy and the host Casey was very responsive!"
United States
John
$149 nightly
The price is $163
Dec 15 - Dec 16
Total with taxes and fees
Modern Desert Oasis Studio in Historic Downtown Yuma
Fridge, microwave, oven, stovetop
Casa Laissez-Faire: A 2800+ SqFt Private Desert Oasis with Private Pool.

Vacation Home in Yuma

Casa Laissez-Faire: A 2800+ SqFt Private Desert Oasis with Private Pool.
2.0 star property
10.0 out of 10, Exceptional, (1)
"Nice place"
United States
Kent W.
$366 nightly
The price is $399
Dec 15 - Dec 16
Total with taxes and fees
Casa Laissez-Faire: A 2800+ SqFt Private Desert Oasis with Private Pool.
Fridge, microwave, stovetop, toaster
Close to Golf! Snowbird Retreat w/ Pool in Yuma

Vacation Home in Yuma Corona

Close to Golf! Snowbird Retreat w/ Pool in Yuma
2.0 star property
$395 nightly
The price is $429
Dec 13 - Dec 14
Total with taxes and fees
Close to Golf! Snowbird Retreat w/ Pool in Yuma
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Luis Hotel Reviews

Super 8 by Wyndham Yuma

Super 8 by Wyndham Yuma

10/10 Excellent
"All good"
Tony 1-night trip
Posted 2 days ago
Super 8 by Wyndham Yuma

Find out more about San Luis

Everything you need to know about San Luis vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the San Luis vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect San Luis vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

San Luis vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in San Luis. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit San Luis in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $29 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on San Luis rentals

At Expedia, we put the best San Luis vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top San Luis rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream San Luis vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around San Luis. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in San Luis?

Yes, we give you a choice of vacation rentals near popular local attractions in San Luis, or you can select a more secluded option if you're looking for relaxation. San Luis is known for its parks.

What's the top vacation rental in San Luis?

One story fully furnished townhouse : Visitors like this San Luis vacation home rental. It is located on a river and has an outdoor pool, a patio, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge, and a stovetop. Kick off your shoes and enjoy yourself with a private yard and a hot tub.

What can I see and do in San Luis?

Explore the area and family-friendly sights such as Z Fun Factory, or get out into nature at a spot like Colorado River. In the larger area, you’ll find San Luis Lakes State Park and Garita Entrance to Mexico.

What are vacation rentals like in San Luis?

Vacation rentals are privately owned properties you can book for a couple days or more in San Luis. Vacation rentals provide amenities like kitchens and laundry facilities so you'll feel right at home. If you're concerned about a clean environment, a vacation rental can provide a sense of seclusion away from public hotel elevators and busy concierge desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great option for family gatherings.