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Santa Isabel Vacation Rentals

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Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for Santa Isabel vacation rentals

A bedroom with a bed, a ceiling fan, a window with curtains, and a view of greenery outside.

1. Mi Verde Horizonte "Panoramic view in Utuado | Nearby river + Nature + WiFi".

Mi Verde Horizonte "Panoramic view in Utuado | Nearby river + Nature + WiFi".
Utuado
10.0 out of 10, Exceptional, (3 reviews)
"Beautiful, clean and the proprietor was extremely helpful in directions to get there; great stay, hope to go back soon."
United States
Santiago C.
$140 nightly
The price is $148
Oct 24 - Oct 25
Total with taxes and fees
Mi Verde Horizonte "Panoramic view in Utuado | Nearby river + Nature + WiFi".
A kitchen with white cabinets, a wooden ceiling, a dining table with a tray of cookies, and a potted plant.

2. Cozy 2BR, Terrace, AC & WiFi near Tanama River

Cozy 2BR, Terrace, AC & WiFi near Tanama River
Utuado
10.0 out of 10, Exceptional, (2 reviews)
"Definitely would stay again! Casa maya has all you need & in such a beautiful area. We loved it!!!"
United States
Kamryn C.
$287 nightly
The price is $304
Oct 13 - Oct 14
Total with taxes and fees
Cozy 2BR, Terrace, AC & WiFi near Tanama River
A spacious living area with a high wooden ceiling, a balcony with a railing, and a modern kitchen in the background.

3. The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico
Adjuntas
9.6 out of 10, Exceptional, (16 reviews)
"Homie place great for relaxing"
United States
Yesenia
$266 nightly
The price is $282
Oct 14 - Oct 15
Total with taxes and fees
The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico
A modern infinity pool with a clear view of the ocean and palm trees.

4. Ventana al Atlantico at Arecibo 681 Ocean Drive

Ventana al Atlantico at Arecibo 681 Ocean Drive
2.5 star property
Arecibo
7.0 out of 10, Good, (296 reviews)
"Everything ok just need some update around the property and more parking and lots of activity around the area Nice view"
United States
Janine
$144 nightly
The price is $154
Oct 13 - Oct 14
Total with taxes and fees
Ventana al Atlantico at Arecibo 681 Ocean Drive
A kitchen counter with a woven basket labeled 'MAKING S'MORE memories,' containing snacks, a bottle, and a glass.

5. Private Romantic Cabin -Heated pool -Nature Escape

Private Romantic Cabin -Heated pool -Nature Escape
San Sebastián
10.0 out of 10, Exceptional, (1 review)
"Peaceful retreat. Felt like I stepped into a book. Just as described. Pictures do not do it justice. Beautiful and tranquil and just what I needed."
United States
Yarissa R.
$351 nightly
The price is $373
Oct 13 - Oct 14
Total with taxes and fees
Private Romantic Cabin -Heated pool -Nature Escape
A modern living room with a white table, blue sofa, ceiling fan, and a small potted plant.

6. Arecibo Hotel 2105

Arecibo Hotel 2105
2.0 star property
Arecibo
7.8 out of 10, Good, (23 reviews)
"The place was clean and the area was quiet most of the time."
United States
Carlos De La
$148 nightly
The price is $161
Oct 19 - Oct 20
Total with taxes and fees
Arecibo Hotel 2105
A compact kitchen with a built-in microwave, a dishwasher, and a sink.

7. Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach

Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach
Quebradillas
10.0 out of 10, Exceptional, (1 review)
$70 nightly
The price is $73
Oct 20 - Oct 21
Total with taxes and fees
Caleno Boricua apartment. Modern luxury apartment 5 minutes from the beach
A wooden table with a bottle of wine and two glasses on it, set against a white wall with green shutters.

8. Nature's Lodge Escape

Nature's Lodge Escape
Sabana Grande
8.0 out of 10, Very good, (7 reviews)
"Clean and organized, love the mountain view."
United States
Maria V.
$114 nightly
The price is $120
Oct 13 - Oct 14
Total with taxes and fees
Nature's Lodge Escape
A hotel room with a large bed, a desk with a computer, a TV, and a window with curtains.

9. Casita Linda

Casita Linda
2.5 star property
Arecibo
7.6 out of 10, Good, (18 reviews)
"Staff was very responsive and helpful"
United States
John
$179 nightly
The price is $200
Nov 10 - Nov 11
Total with taxes and fees
Casita Linda
A coastal property with a wooden deck, white lounge chairs, and a staircase leading to a balcony overlooking the ocean.

10. Casa Colibrí

Casa Colibrí
2.5 star property
Arecibo
4.4 out of 10, (18 reviews)
"The property worked for my stay—I was in town for a funeral and needed something affordable. It has good potential, but several issues made the experience less than ideal: no mirror, no hot water, no Wi‑Fi, and some needed handyman repairs. If these are fixed, it could be a solid place."
United States
Jose
$128 nightly
The price is $146
Oct 13 - Oct 14
Total with taxes and fees
Casa Colibrí
A modern house with a pathway leading to the entrance, surrounded by greenery and illuminated by ground lights.

11. Utopia Luxury Villa -Private Pool,Hydromassage Jacuzzi & Near Amazing Beaches

Utopia Luxury Villa -Private Pool,Hydromassage Jacuzzi & Near Amazing Beaches
Hatillo
9.0 out of 10, Wonderful, (64 reviews)
"The house was just as pictured! Very clean and spacious. The host was very attentive and accommodating. We had 14 ppl on our family vaca. The host also does various tours around the island which makes it convenient. We had a great time! Will stay again."
United States
Jennilee R.
$737 nightly
The price is $782
Oct 13 - Oct 14
Total with taxes and fees
Utopia Luxury Villa -Private Pool,Hydromassage Jacuzzi & Near Amazing Beaches
A neatly arranged bedroom with a bed, a bedside table with a lamp, and a chair.

12. Boricua 3 | Cozy Eco-Stay w/ WiFi + A/C

Boricua 3 | Cozy Eco-Stay w/ WiFi + A/C
Rio Pietro
$199 nightly
The price is $219
Oct 13 - Oct 14
Total with taxes and fees
Boricua 3 | Cozy Eco-Stay w/ WiFi + A/C
Spa

13. Tropical Studio Boutique - Cerca de Gozalandia

Tropical Studio Boutique - Cerca de Gozalandia
Hato Arriba
10.0 out of 10, Exceptional, (1 review)
"Ok"
United States
Wilfredo
$102 nightly
The price is $102
Oct 13 - Oct 14
Total with taxes and fees
Tropical Studio Boutique - Cerca de Gozalandia
A modern two-story house with a covered porch, two chairs, and a small garden with plants and rocks.

14. Isabela, Tiny House 2.

Isabela, Tiny House 2.
Isabela
10.0 out of 10, Exceptional, (18 reviews)
"Nice place, quite location beautiful "
United States
Carmen
$145 nightly
The price is $154
Oct 13 - Oct 14
Total with taxes and fees
Isabela, Tiny House 2.
A living room with a sofa, a coffee table, a chair, and a potted plant.

15. The Eden Oasis - A Private Getaway

The Eden Oasis - A Private Getaway
Bajadero
10.0 out of 10, Exceptional, (1 review)
"The home was beautiful and it was close to the beaches and restaurants. We had a wonderful stay and there were several pleasant surprises. The host was very responsive and welcoming!"
United States
Gladys G.
$216 nightly
The price is $230
Oct 21 - Oct 22
Total with taxes and fees
The Eden Oasis - A Private Getaway
A neatly made bed with white bedding, a dark headboard, and a bedside table with a lamp and a digital clock.

16. Cozy Yauco Studio | A/C + WiFi · Boricua 2

Cozy Yauco Studio | A/C + WiFi · Boricua 2
Yauco
$204 nightly
The price is $224
Oct 13 - Oct 14
Total with taxes and fees
Cozy Yauco Studio | A/C + WiFi · Boricua 2
A kitchen with dark cabinets, a stainless steel refrigerator, a stove, and a sink.

17. Marie Guest House w A/C

Marie Guest House w A/C
Camuy
10.0 out of 10, Exceptional, (1 review)
"好"
China
善安
$239 nightly
The price is $254
Oct 13 - Oct 14
Total with taxes and fees
Marie Guest House w A/C
A compact living space with a kitchenette, a flat-screen TV mounted on the wall, a black leather sofa, and a wooden floor.

18. Colombian Boricua Apartment 5 minutes from the beach luxury

Colombian Boricua Apartment 5 minutes from the beach luxury
Quebradillas
10.0 out of 10, Exceptional, (3 reviews)
"Great place to stay! It was clean, comfortable, and exactly as expected. The host was kind and responsive, and everything went smoothly. I would definitely stay here again and highly recommend it!"
United States
Joshua M.
$66 nightly
The price is $69
Oct 17 - Oct 18
Total with taxes and fees
Colombian Boricua Apartment 5 minutes from the beach luxury
A bedroom with a bed, bedside lamps, a sofa, a coffee table, and a door leading to a balcony.

19. Elegant 1-bedroom suite with pool and hot tub in historical Sabana Grande

Elegant 1-bedroom suite with pool and hot tub in historical Sabana Grande
Sabana Grande
$265 nightly
The price is $282
Oct 20 - Oct 21
Total with taxes and fees
Elegant 1-bedroom suite with pool and hot tub in historical Sabana Grande
A bathroom with a shower, a window, and a shelf with toiletries.

20. Casa vacacional en Arenales Isabela

Casa vacacional en Arenales Isabela
3.5 star property
Isabela
9.0 out of 10, Wonderful, (50 reviews)
"The property was nice and clean quiet area had everything included inside the house sent you air and the bedrooms were nice"
United States
Jaime
$184 nightly
The price is $201
Oct 13 - Oct 14
Total with taxes and fees
Casa vacacional en Arenales Isabela
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Isabel Hotel Reviews

Arecibo Inn

Arecibo Inn

8/10 Good
"Excelente"
Johanna 1-night trip
Posted less than an hour ago
Arecibo Inn

Find out more about Santa Isabel

Everything you need to know about Santa Isabel vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Isabel vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Isabel vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa Isabel vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Isabel. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa Isabel in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $120 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa Isabel rentals

At Expedia, we put the best Santa Isabel vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa Isabel rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Isabel vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Isabel. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santa Isabel?

Yes, we have vacation rentals near top attractions in Santa Isabel, or you can choose a secluded option if you'd like a relaxing place to stay.

What's the top vacation rental that Santa Isabel has to offer?

3-Bedroom House in Quebradillas: You might want to consider this vacation home rental near Santa Isabel, which is located near the airport and has a terrace, a garden, and free WiFi to put you at ease in your new surroundings. This vacation rental also comes with free parking to give you added peace of mind.

What can I see and do in Santa Isabel?

Explore the area and family-friendly sights such as Maricao Fish Hatchery, or get out into nature at a spot like Tanamá River. Camuy River Cave Park and Lago Garzas are a couple of places you'll find in the larger area.

What are vacation rentals like in Santa Isabel?

Vacation rentals are privately owned accommodations you can book for a short or long stay in Santa Isabel. Vacation rentals feature extras such as patios, hot tubs, and fire pits so you'll feel right at home. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from shared hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a traditional hotel, which makes a vacation rental a popular option for small groups.