Title: Visit Santa María Mixtequilla: 2026 Travel Guide for Santa María Mixtequilla, Oaxaca | Expedia.com [Hotels in Santa María Mixtequilla](https://expedia.com/Santa-Maria-Mixtequilla-Hotels.d553248635640631214.Travel-Guide-Hotels)[Vacation Rentals in Santa María Mixtequilla](https://expedia.com/Santa-Maria-Mixtequilla-Vacation-Rentals.d553248635640631214.Travel-Guide-VacationRentals)[Car Rentals in Santa María Mixtequilla](https://expedia.com/Car-Rentals-In-Santa-Maria-Mixtequilla.d553248635640631214.Car-Rental-Guide)[Santa María Mixtequilla Vacation Packages](https://expedia.com/Santa-Maria-Mixtequilla.d553248635640631214.Destination-Travel-Guides) # Santa María Mixtequilla ## Travel Guide ## Visit Santa María Mixtequilla ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=DX_SPRING_PROMO_553248635640631214) - Santa María Mixtequilla Hotel Deals - Vacation Rentals in Santa María Mixtequilla ![One Salina Cruz](https://images.trvl-media.com/lodging/7000000/6840000/6831600/6831542/df2bb342_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### One Salina Cruz Carretera Transistmica No. 10 Km. 5 Salina Cruz OAX $48 nightly $58 total Feb 27 - Feb 28 Total with taxes and fees Book a stay at this business-friendly hotel in Salina Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Zocalo of Salina Cruz and ... [](https://expedia.com/Hotel-Search?startDate=2%2F27%2F2026&endDate=2%2F28%2F2026&selected=6831542&PinnedHotelID=6831542&HadPinnedHotel=true®ionId=553248635640631214) ![Hotel Santa Cruz Juchitan](https://images.trvl-media.com/lodging/33000000/32860000/32858700/32858642/300fd40c_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hotel Santa Cruz Juchitan Carretera Transistmica KM 818 Juchitan de Zaragoza OAX Stay at this hotel in Juchitan de Zaragoza. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attraction Jardín Juárez is located nearby. [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F7%2F2026&endDate=3%2F8%2F2026&selected=32858642&PinnedHotelID=32858642&HadPinnedHotel=true®ionId=553248635640631214) [](https://expedia.com/Hotel-Search?startDate=3%2F7%2F2026&endDate=3%2F8%2F2026&selected=32858642&PinnedHotelID=32858642&HadPinnedHotel=true®ionId=553248635640631214) ![City Express by Marriott Salina Cruz](https://images.trvl-media.com/lodging/7000000/6930000/6924400/6924397/5fe44611_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### City Express by Marriott Salina Cruz Carretera Transísmica Km. 293.9 Salina Cruz OAX $55 nightly $66 total Feb 24 - Feb 25 Total with taxes and fees Book a stay at this business-friendly hotel in Salina Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Zocalo of Salina Cruz and ... 8.4/10 Very Good! (314 reviews) Nice Reviewed on Jul 3, 2025 [](https://expedia.com/Hotel-Search?startDate=2%2F24%2F2026&endDate=2%2F25%2F2026&selected=6924397&PinnedHotelID=6924397&HadPinnedHotel=true®ionId=553248635640631214) [See all 23 properties in Santa María Mixtequilla](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=2%2F22%2F2026&endDate=2%2F23%2F2026®ionId=553248635640631214) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![LAS PALMERAS ](https://images.trvl-media.com/lodging/108000000/107390000/107384700/107384697/c03acbc5_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### LAS PALMERAS AVENIDA PUNTA CONEJO, PLAYA BRASIL Salina Cruz MEX Book a stay at this beach cabin in Salina Cruz. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Las Escolleras Beach and Salina Cruz Lighthouse ... [](https://expedia.com/Salina-Cruz-Hotels-LAS-PALMERAS.h107384697.Hotel-Information) ![House with pool a few meters from the beach come and rest!!!](https://images.trvl-media.com/lodging/77000000/76260000/76255600/76255533/0563ece2_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### House with pool a few meters from the beach come and rest!!! Guelaguechi OAX Stay at this vacation home in Tehuantepec. Enjoy air conditioning and an outdoor pool. Popular attractions Playa Azul and Playa Brasil are located nearby. [](https://expedia.com/Tehuantepec-Hotels-House-With-Pool-A-Few-Meters-From-The-Beach-Come-And-Rest.h76255533.Hotel-Information) [See all properties in Santa María Mixtequilla](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience®ionId=553248635640631214&sort=VACATION_RENTAL) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Check Santa María Mixtequilla hotel availability [Tonight ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640631214&startDate=2026-02-21&endDate=2026-02-22)[Feb 21 - Feb 22](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640631214&startDate=2026-02-21&endDate=2026-02-22) [Tomorrow night ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640631214&startDate=2026-02-22&endDate=2026-02-23)[Feb 22 - Feb 23](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640631214&startDate=2026-02-22&endDate=2026-02-23) [Next weekend ](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640631214&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026)[Feb 27 - Mar 1](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true®ionId=553248635640631214&startDate=2%2F27%2F2026&endDate=3%2F1%2F2026) ## Cities near Santa María Mixtequilla ![Mujeres tehuanas](https://images.trvl-media.com/place/6305155/d7d82b10-26e4-4c13-809a-93b72fe4a7ba.jpg?impolicy=fcrop&w=512&h=288&q=medium) ### Tehuantepec - Cities near Santa María Mixtequilla - Places of interest [Tehuantepec](https://expedia.com/Tehuantepec.dx6305155)[San Blas Atempa](https://expedia.com/San-Blas-Atempa.dx553248635640638731)[San Pedro Comitancillo](https://expedia.com/San-Pedro-Comitancillo.dx553248635640640038) - [Las Escolleras Beach ](https://expedia.com/Las-Escolleras-Beach-Mexico.d6298581.Vacation-Attraction) - [Tehuantepec House of Culture ](https://expedia.com/Tehuantepec-House-Of-Culture-Tehuantepec.d6302956.Vacation-Attraction) - [Playa Azul ](https://expedia.com/Playa-Azul-Mexico.d6298579.Vacation-Attraction) - [Salina Cruz Lighthouse ](https://expedia.com/Salina-Cruz-Lighthouse-Salina-Cruz.d6298576.Vacation-Attraction) - [Church of Asunción Ixtaltepec ](https://expedia.com/Church-Of-Asuncion-Ixtaltepec-Asuncion-Ixtaltepec.d553248621566661416.Vacation-Attraction) - [Jardín Juárez ](https://expedia.com/Jardin-Juarez-Juchitan-de-Zaragoza.d553248621532976980.Vacation-Attraction) - [Guiengola ](https://expedia.com/Guiengola-Tehuantepec.d553248621532976979.Vacation-Attraction) - [Guiengola Archaeological Site ](https://expedia.com/Guiengola-Archaeological-Site-Tehuantepec.d6302936.Vacation-Attraction)