Santa María Vacation Rentals

Check prices for these dates

In two weeks
Nov 20 - Nov 22
In two months
Jan 1 - Jan 3
In three months
Jan 29 - Jan 31
In four months
Feb 26 - Feb 28

Our top choices for Santa María vacation rentals

A wooden deck with a pool, lounge chairs, and umbrellas overlooking the ocean.

1. Karibao Resort Town

Karibao Resort Town
4.0 star property
Playas
8.2 out of 10, Very good, (23 reviews)
"Food was amazing"
United States
Walter
$101 nightly
The price is $112
Nov 27 - Nov 28
Karibao Resort Town
A coastal hotel with a beach view, a tennis court, and a parking area.

2. Departamento 1304 Ocean Club Playas

Departamento 1304 Ocean Club Playas
3.0 star property
Playas
8.0 out of 10, Very good, (4 reviews)
"excelente departamento, muy bien ubicado, limpio y acogedor y con una vista muy bonita "
Ecuador
Cesar
$115 nightly
The price is $115
Dec 3 - Dec 4
Departamento 1304 Ocean Club Playas
A modern living room with a sofa, a glass coffee table, and a dining area with chairs. A large window offers a view of the ocean.

3. Modern Ocean Footage Pool/Hot Tub

Modern Ocean Footage Pool/Hot Tub
Guayaquil
10.0 out of 10, Exceptional, (1 review)
"This apartment is located right by the beach. You can hear the ocean as you fall asleep and all day long. The sunset views are spectacular. There is a hammock on the balcony to lay in to read a book or watch the sunset while enjoying the ocean breeze. You can see the ocean from the living room and bedroom. The bed is comfortable with nice linens. The kitchen is stocked with all the items you would need. I recommend shopping for groceries beforehand. You’ll need a taxi to reach stores or...
United States
Claudia M.
$128 nightly
The price is $128
Nov 8 - Nov 9
Modern Ocean Footage Pool/Hot Tub
A swimming pool area with tiled walls and a clear view of the pool.

4. Wake Up to an Ocean View from Your Private Balcony

Wake Up to an Ocean View from Your Private Balcony
General Villamil
$119 nightly
The price is $133
Nov 8 - Nov 9
Wake Up to an Ocean View from Your Private Balcony
A balcony with two chairs facing a beach view.

5. Oceanfront apartment, swimming pool, automatic check-in

Oceanfront apartment, swimming pool, automatic check-in
Guayaquil
$142 nightly
The price is $142
Nov 8 - Nov 9
Oceanfront apartment, swimming pool, automatic check-in
A modern living room with a flat-screen TV, a sofa with patterned cushions, a balcony with a view of the ocean, and a painting on the wall.

6. Beachfront apartment in the Altamar II complex

Beachfront apartment in the Altamar II complex
Posorja
$98 nightly
The price is $98
Nov 9 - Nov 10
Beachfront apartment in the Altamar II complex
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Find vacation rentals that suit your style

Apartment image
Apartments
Apartments
Condo image
Condos
Condos

Top Santa María Hotel Reviews

A beachside resort with a swimming pool, thatched umbrellas, and a view of the ocean.
Hotel Presidente Beach Playas

Hotel Presidente Beach Playas

Hotel Presidente Beach Playas
Playas

10/10 Excellent

Tener más opciones de piqueo para disfrutar en la Pisina
United States
Nathalia
Reviewed September 11, 2026
Hotel Presidente Beach Playas

Find out more about Santa María

Everything you need to know about Santa María vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa María vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa María vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa María vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa María. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa María in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $97 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa María rentals

At Expedia, we put the best Santa María vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa María rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa María vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa María. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently Asked Questions

Can I find a vacation rental in Santa María?

Yes, you can find vacation rentals close to top local attractions in Santa María, or you can go with a secluded option if you're looking for a relaxing stay.

What are some of the best vacation home rentals in Santa María?

Casa Playas 1: You might want to consider this Santa María vacation home rental for your stay. It is located on the waterfront and has an outdoor pool, a terrace, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

How many vacation rentals will I find in Santa María?

Expedia has 10 vacation rentals for your stay in Santa María.

What can I see and do in Santa María?

While you're exploring the area, General Villamil Beach and Varadero Beach are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Paseo Shopping Playas and Estero Lagarto.

What are vacation rentals like in Santa María?

Vacation rentals are privately owned accommodations you can stay in for a few days or a quick weekend in Santa María. Vacation rentals provide amenities such as WiFi and washers and dryers so your stay will be comfortable. If you're concerned about a clean environment, vacation rentals can offer a sense of security away from shared hotel elevators and bustling concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental a great option for small groups.