Title: Sister Islands Vacation Rentals : Search Short-Term Rentals | Expedia.com [Sister Islands Travel Guide](https://expedia.com/Sister-Islands.dx553248633946460050)[Hotels in Sister Islands](https://expedia.com/Sister-Islands-Hotels.d553248633946460050.Travel-Guide-Hotels)[Flights to Sister Islands](https://expedia.com/Cheap-Flights-To-Sister-Islands.d553248633946460050.Travel-Guide-Flights)[Car Rentals in Sister Islands](https://expedia.com/Car-Rentals-In-Sister-Islands.d553248633946460050.Car-Rental-Guide)[Sister Islands Vacation Packages](https://expedia.com/Sister-Islands.d553248633946460050.Destination-Travel-Guides) ![#Endlesssummer Great wall diving on Little Cayman. Colorful sponges, lots of fish and beautiful tropical waters.](https://images.trvl-media.com/place/6307499/8505b9ac-5e4b-4d71-9462-2667bf474e3e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Bob Bowdey ![](https://images.trvl-media.com/place/6307499/8505b9ac-5e4b-4d71-9462-2667bf474e3e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_bundle_and_save.svg) ### Bundle & Save Get more, spend less whenever you see Bundle & Save deals - ![](https://a.travel-assets.com/travel-assets-manager/pictograms-expedia/light__onekey.svg) ### OneKeyCash Earn OneKeyCash on all your eligible bookings - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light_ftc.svg) ### Upfront pricing We are not like the others - we include taxes and fees ## Check prices for these dates In two weeks [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=553248633946460050&startDate=2026-03-13&endDate=2026-03-15&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [Apr 24 - Apr 26](https://www.expedia.com/Hotel-Search?regionId=553248633946460050&startDate=2026-04-24&endDate=2026-04-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In three months [May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=553248633946460050&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In four months [Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=553248633946460050&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.com/deals?rfrr=VR_SPRING_PROMO_553248633946460050) ## Find vacation rentals that suit your style Apartments [](https://www.expedia.com/Hotel-Search?destination=Sister+Islands%2C+Cayman+Islands®ionId=553248633946460050&latLong=19.699941%2C-79.911975&adults=2&startDate=2026-05-27&d1=2026-05-27&endDate=2026-05-30&d2=2026-05-30&lodging=APARTMENT) Villas [](https://www.expedia.com/Hotel-Search?destination=Sister+Islands%2C+Cayman+Islands®ionId=553248633946460050&latLong=19.699941%2C-79.911975&adults=2&startDate=2026-05-27&d1=2026-05-27&endDate=2026-05-30&d2=2026-05-30&lodging=VILLA) Private vacation homes [](https://www.expedia.com/Hotel-Search?destination=Sister+Islands%2C+Cayman+Islands®ionId=553248633946460050&latLong=19.699941%2C-79.911975&adults=2&startDate=2026-05-27&d1=2026-05-27&endDate=2026-05-30&d2=2026-05-30&lodging=VACATION_HOME) Condos [](https://www.expedia.com/Hotel-Search?destination=Sister+Islands%2C+Cayman+Islands®ionId=553248633946460050&latLong=19.699941%2C-79.911975&adults=2&startDate=2026-05-27&d1=2026-05-27&endDate=2026-05-30&d2=2026-05-30&lodging=CONDO) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSister-Islands-Vacation-Rentals.d553248633946460050.Travel-Guide-VacationRentals)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSister-Islands-Vacation-Rentals.d553248633946460050.Travel-Guide-VacationRentals) ## Top Sister Islands Hotel Reviews ![Incredible Views, Waterfront Luxury Private Villa with Central AC](https://images.trvl-media.com/lodging/32000000/31730000/31721600/31721553/5fefea2b_y.jpg) ### Incredible Views, Waterfront Luxury Private Villa with Central AC 10/10 Excellent "Everything was perfect. Would definitely stay here again if come back to the Brac." [](https://expedia.com/Tibbetts-Turn-Hotels-Everything-About-This-Place-Is-First-Class.h31721553.Hotel-Information) ![Luxury Oceanfront Villa, 2 Primary Suites + 3rd bdrm, Pool ](https://images.trvl-media.com/lodging/45000000/44070000/44065300/44065259/471436e6_y.jpg) ### Luxury Oceanfront Villa, 2 Primary Suites + 3rd bdrm, Pool 10/10 Excellent "Amazing property! It has everything we needed. Master suites were very comfortable. Added bonus was being able to see and hear the ocean from bed. Very private location. We enjoyed hours on the beach! Hosts were very responsive! " [](https://expedia.com/West-End-Hotels-Luxury-Oceanfront-Villa.h44065259.Hotel-Information) ![Le Soleil d'Or CaymanBrac](https://images.trvl-media.com/lodging/75000000/74430000/74421900/74421869/72668cc8_y.jpg) ### Le Soleil d'Or CaymanBrac 10/10 Excellent "The room and amenities were spotless. The food was excellent as well as the service. Beautiful and quiet" [](https://expedia.com/George-Town-Hotels-Le-Soleil-DOr-CaymanBrac.h74421869.Hotel-Information) ![Blossom Village Cottage – Charming Beachfront Cottage by Cayman Villas.](https://images.trvl-media.com/lodging/22000000/21670000/21660900/21660830/be3fd792_y.jpg) ### Blossom Village Cottage – Charming Beachfront Cottage by Cayman Villas. 10/10 Excellent "The house, the location and all the people were awesome! We had 4 teenagers traveling with us and I cannot tell you how happy everyone was that they had their own little cottage. The water, the property was absolutely amazing! The kitchen was well stocked and everything was spotless. I am a very picky traveler and I cannot say enough good things about this property." [](https://expedia.com/Little-Cayman-Hotels-Blossom-Village-Cottage-Charming-Cottage-By-Cayman-Villas.h21660830.Hotel-Information) ![Snorkelers & Divers Paradise-Cayman Brac-2 Bedroom On Beach With Deck ](https://images.trvl-media.com/lodging/33000000/32170000/32168400/32168337/de346a61_y.jpg) ### Snorkelers & Divers Paradise-Cayman Brac-2 Bedroom On Beach With Deck 10/10 Excellent "Perfect location, lovely property. " [](https://expedia.com/West-End-Hotels-Snorkelers-Divers-Paradise-Cayman-Brac-2-Bedroom-On-Beach-With-Deck.h32168337.Hotel-Information) ![Ocean view from every room ,quiet neighborhood family friendly.Bluff view ](https://images.trvl-media.com/lodging/100000000/99520000/99517100/99517026/87e54322_y.jpg) ### Ocean view from every room ,quiet neighborhood family friendly.Bluff view 6/10 Okay "Condo was rundown and not very clean - it reeked (possibly due to unresolved water leaks?), only one shower had warm water, the freezer couldn’t be opened, the fridge sounded like it was about to blow, etc. Dishes had to be washed Before use, kitchen floor had sticky patches (?). Not great for families who like to cook/eat at home. Grounds were well kept, location was quiet and peaceful and the snorkeling off the beach was awesome!" [](https://expedia.com/East-End-Hotels-Ocean-View-From-Every-Room.h99517026.Hotel-Information) ![Private 2-b beachfront cottage w/ hammocks, screened-in veranda, sunsets & more!](https://images.trvl-media.com/lodging/34000000/33490000/33486700/33486647/58b05173_y.jpg) ### Private 2-b beachfront cottage w/ hammocks, screened-in veranda, sunsets & more! 10/10 Excellent "Place is super clean, location was perfect. Peaceful and very relaxing. Gorgeous sunsets. We definitely want to come back. " [](https://expedia.com/West-End-Hotels-Sunsets.h33486647.Hotel-Information) ![Serenity On The Bay2 - Two Bed Apt Close to Supermarkets, Shops and Restaurants!](https://images.trvl-media.com/lodging/45000000/44680000/44670500/44670448/17f65372_y.jpg) ### Serenity On The Bay2 - Two Bed Apt Close to Supermarkets, Shops and Restaurants! 10/10 Excellent "Host was very helpful arranging taxis, great, private spot. Great snorkeling right out front of the house. Hermit crabs everywhere. Not a soul on the beach, no noise from neighbors. This is the perfect spot if you’re looking for solitude (which I usually am). You definitely want to rent a car. There are only 2 taxis on the island, and the shoulders on the road aren’t ideal for walking. " [](https://expedia.com/West-End-Hotels-Serenity-On-The-Bay2-Two-Bed-Apt-Close-To-Supermarkets.h44670448.Hotel-Information) ![PLEASE COME AND RELAX ON OUR PRIVATE BEACH!](https://images.trvl-media.com/lodging/34000000/33740000/33736200/33736125/7ac30eff_y.jpg) ### PLEASE COME AND RELAX ON OUR PRIVATE BEACH! 10/10 Excellent "A great weekend get away" [](https://expedia.com/Spot-Bay-Hotels-PLEASE-COME-AND-RELAX-ON-OUR-PRIVATE-BEACH.h33736125.Hotel-Information) ## Find out more about Sister Islands **Everything you need to know about Sister Islands vacation rentals** Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Sister Islands vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on. There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Sister Islands vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. **Sister Islands vacation rentals: An excellent choice for every season** Whenever you want to travel, a warm welcome awaits you in Sister Islands. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Sister Islands in high season. Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals! **How to find incredible deals on Sister Islands rentals** At Expedia, we put the best Sister Islands vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. To find some top Sister Islands rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Sister Islands vacation. If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Sister Islands. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. ## Explore a world of travel with Expedia - Trending destinations on Expedia.com - All accommodation types in Sister Islands ### Trending destinations on Expedia.com - [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals) - [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals) - [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals) - [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals) - [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals) - [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals) - 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