$381 Cheap Flights from Johannesburg (JNB) to São Tomé Island (TMS)

View $381 flight on Fri, Feb 27, 2026Opens in a new window

Popular airlines from O.R. Tambo Intl. Airport (JNB) to São Tomé Island (TMS-São Tomé Intl.)

Cheap Flights from Johannesburg to São Tomé Island (JNB-TMS)

Prices were available within the past 7 days and start at $381 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from O.R. Tambo Intl. Airport (JNB) to Sao Tome Intl. Airport (TMS) cost?
Get a cheap one-way flight from $381 or cheap return flight from O.R. Tambo Intl. Airport (JNB) to Sao Tome Intl. Airport (TMS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from O.R. Tambo Intl. Airport (JNB) to Sao Tome Intl. Airport (TMS)?
is the most affordable month to fly from JNB to TMS. Timing your trip outside of the busy season is often the key to finding better deals on flights.
What is the cheapest airline that flies from O.R. Tambo Intl. Airport (JNB) to Sao Tome Intl. Airport (TMS)?
Use the filter tool on Expedia to compare different airlines and find the most affordable carrier that'll fly you from JNB to TMS. Then, sort your results by "Price (lowest to highest)" to pick up a great deal.
How many flights per day from O.R. Tambo Intl. Airport (JNB) to Sao Tome Intl. Airport (TMS)?
Direct flights from O.R. Tambo Intl. Airport (JNB) to Sao Tome Intl. Airport (TMS) aren't available daily, so you'll have to take a flight with a layover. Explore your options with our filter tool. Enter your travel dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from JNB to TMS?
Usually you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary based on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from O.R. Tambo Intl. Airport (JNB) to Sao Tome Intl. Airport (TMS)?
Opt for a flight from O.R. Tambo Intl. Airport (JNB) to Sao Tome Intl. Airport (TMS) that leaves before 3 PM to reduce the risk of cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from O.R. Tambo Intl. Airport (JNB) to Sao Tome Intl. Airport (TMS) last-minute?
Holding off until right before your break to book a flight from JNB to TMS often results in higher prices. Although you may find some last-minute discounts, they aren't always guaranteed. Allow some flexibility in your schedule to boost your chances of landing a bargain.
Is it cheaper to book a JNB to TMS flight and hotel package?
Securing a JNB to TMS flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your trip all in one place. Choose from our impressive range of hotels and then add car rentals, flights and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from O.R. Tambo Intl. Airport (JNB) to Sao Tome Intl. Airport (TMS)?
Typically, you can reschedule or cancel your JNB to TMS flight. However, additional fees may apply, especially if you booked more than 24 hours ago. Check your itinerary for the airline's fees and guidelines on flight changes, or if you want further information, go to our Customer Service portal.

Travel information

Origin airport
O.R. Tambo Intl.
Destination airport
São Tomé Intl.
Distance
2325 mi

Book with confidence

Johannesburg to São Tomé Island Flights

The cheapest times to fly from Johannesburg to São Tomé Island

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Johannesburg to São Tomé Island are during the month of . You can find some of the cheapest flights from Johannesburg to São Tomé Island with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Johannesburg to São Tomé Island

Sunday is one of the best days to book for cheap flights from Johannesburg to São Tomé Island: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Johannesburg to São Tomé Island

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Johannesburg to São Tomé Island in 2025. You can also book with separate airlines for your outbound and return journeys, from $381 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Johannesburg to São Tomé Island flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Johannesburg to São Tomé Island airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Johannesburg to São Tomé Island Flights
*Available to One Key members.