Find 5 Star Hotels in Prenestino-Labicano from $132

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Check availability on Prenestino-Labicano 5 Star Hotels

Our top choices for Prenestino-Labicano 5-star hotels

Sauna, steam room, Turkish bath, body treatments, aromatherapy
The Westin Excelsior, Rome

The Westin Excelsior, Rome

The Westin Excelsior, Rome
5.0 star property
Rome City Centre
8.2 out of 10, Very Good, (744)
"Spacious rooms!!!"
United States
Milana
$363 nightly
The price is $423
Jan 7 - Jan 8, 2026
Total with taxes and fees
The Westin Excelsior, Rome
Exterior
NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento

NH Collection Roma Palazzo Cinquecento
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1000)
"The hotel was the best location to be at. Amazing stay and so convenient."
United States
Jalin
$280 nightly
The price is $331
Jan 9 - Jan 10, 2026
Total with taxes and fees
NH Collection Roma Palazzo Cinquecento
Sports facility
Rome Cavalieri, A Waldorf Astoria Hotel

Rome Cavalieri, A Waldorf Astoria Hotel

Rome Cavalieri, A Waldorf Astoria Hotel
5.0 star property
Trionfale
9.2 out of 10, Wonderful, (1002)
"I loved this place, the food and the staff!!"
United States
Arenthia
$339 nightly
The price is $396
Jan 8 - Jan 9, 2026
Total with taxes and fees
Rome Cavalieri, A Waldorf Astoria Hotel
Restaurant
Sofitel Rome Villa Borghese

Sofitel Rome Villa Borghese

Sofitel Rome Villa Borghese
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (968)
"Professional staff, luxurious surroundings, excellent location, very nice accommodations - all in all a great experience. "
Sweden
Daniel
$393 nightly
The price is $455
Dec 14 - Dec 15
Total with taxes and fees
Sofitel Rome Villa Borghese
Outdoor spa tub
QC Grand Hotel Roma

QC Grand Hotel Roma

QC Grand Hotel Roma
5.0 star property
Fiumicino
9.0 out of 10, Wonderful, (1005)
"Amazing stay!!!"
United States
Kathryn
$208 nightly
The price is $240
Jan 7 - Jan 8, 2026
Total with taxes and fees
QC Grand Hotel Roma
2 restaurants, Italian cuisine
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World

Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1000)
"Excelente hotel "
Mexico
Miguel
$611 nightly
The price is $696
Jan 9 - Jan 10, 2026
Total with taxes and fees
Anantara Palazzo Naiadi Rome Hotel - A Leading Hotel of the World
Exterior
InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG

InterContinental Rome Ambasciatori Palace by IHG
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (156)
"Great Staff Great Location"
Canada
cristina
$510 nightly
The price is $584
Jan 5 - Jan 6, 2026
Total with taxes and fees
InterContinental Rome Ambasciatori Palace by IHG
Property amenity
W Rome

W Rome

W Rome
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (204)
"Amazing hotel, wonderful staff, convenience "
Canada
Anna
$426 nightly
The price is $491
Jan 5 - Jan 6, 2026
Total with taxes and fees
W Rome
Exterior
Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World

Baglioni Hotel Regina - The Leading Hotels of the World
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (500)
"Excellent hotel with great sraff"
United Kingdom
Gary
$482 nightly
The price is $554
Jan 9 - Jan 10, 2026
Total with taxes and fees
Baglioni Hotel Regina - The Leading Hotels of the World
2 bars/lounges
Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica

Radisson Collection Hotel, Roma Antica
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (147)
"Clean, good breakfast, walkable to major historical ruins"
Canada
Pam
$260 nightly
The price is $309
Jan 11 - Jan 12, 2026
Total with taxes and fees
Radisson Collection Hotel, Roma Antica
Restaurant
Six Senses Rome

Six Senses Rome

Six Senses Rome
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (58)
"Amazing staff, beautifully decorated hotel, super amenities. Truly wonderful find in the heart of Rome."
United States
Sergio Alfonso
$1,095 nightly
The price is $1,228
Dec 18 - Dec 19
Total with taxes and fees
Six Senses Rome
Garden
Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World

Villa Agrippina Gran Meliá - The Leading Hotels of the World
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (935)
"Beautiful hotel, very clean, staff so friendly and helpful Would definitely stay again!"
United Kingdom
debra jane
$467 nightly
The price is $537
Jan 8 - Jan 9, 2026
Total with taxes and fees
Villa Agrippina Gran Meliá - The Leading Hotels of the World
View from property
Sina Bernini Bristol, Autograph Collection

Sina Bernini Bristol, Autograph Collection

Sina Bernini Bristol, Autograph Collection
5.0 star property
Rome City Centre
8.2 out of 10, Very Good, (542)
"Amazing staff service and beautiful room "
United States
Samantha
$356 nightly
The price is $415
Dec 15 - Dec 16
Total with taxes and fees
Sina Bernini Bristol, Autograph Collection
Property entrance
Grand Hotel Palace

Grand Hotel Palace

Grand Hotel Palace
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1003)
"The location was amazing and the staff was really friendly. The restaurant in the hotel was really good too. "
United States
Anuj
$215 nightly
The price is $260
Dec 13 - Dec 14
Total with taxes and fees
Grand Hotel Palace
View from property
Palazzo Manfredi – Small Luxury Hotels of the World

Palazzo Manfredi – Small Luxury Hotels of the World

Palazzo Manfredi – Small Luxury Hotels of the World
5.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (638)
"The rooftop restaurant for breakfast was amazing.. eat and enjoy the view of the coliseum, and archeological dig… Amazing food selection "
United States
Leslie
$399 nightly
The price is $463
Dec 16 - Dec 17
Total with taxes and fees
Palazzo Manfredi – Small Luxury Hotels of the World
Terrace/patio
Hotel Raphaël – Relais & Châteaux

Hotel Raphaël – Relais & Châteaux

Hotel Raphaël – Relais & Châteaux
5.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1000)
"The staff, room, and amenities were all excellent."
United States
Jason
$242 nightly
The price is $289
Dec 16 - Dec 17
Total with taxes and fees
Hotel Raphaël – Relais & Châteaux
Terrace/patio
Hotel Locarno

Hotel Locarno

Hotel Locarno
5.0 star property
Rome City Centre
9.8 out of 10, Exceptional, (520)
"Great location and a beautiful hotel. Great service. "
United States
Mark
$468 nightly
The price is $538
Dec 15 - Dec 16
Total with taxes and fees
Hotel Locarno
Property amenity
Aleph Rome Hotel Curio Collection by Hilton

Aleph Rome Hotel Curio Collection by Hilton

Aleph Rome Hotel Curio Collection by Hilton
5.0 star property
Rome City Centre
9.4 out of 10, Exceptional, (463)
"Stunning property! "
United States
Kaitlin
$362 nightly
The price is $421
Dec 14 - Dec 15
Total with taxes and fees
Aleph Rome Hotel Curio Collection by Hilton
Restaurant
Palazzo Roma - The Leading Hotels of the World

Palazzo Roma - The Leading Hotels of the World

Palazzo Roma - The Leading Hotels of the World
5.0 star property
Rome City Centre
10.0 out of 10, Exceptional, (106)
"Great location, beautiful property, very well run and managed. "
United Kingdom
John
$431 nightly
The price is $497
Dec 18 - Dec 19
Total with taxes and fees
Palazzo Roma - The Leading Hotels of the World
Banquet hall
Hassler Roma

Hassler Roma

Hassler Roma
5.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (154)
"We travel a lot one of the best hotels we’ve ever stayed in"
United States
Joel
$1,416 nightly
The price is $1,581
Dec 16 - Dec 17
Total with taxes and fees
Hassler Roma
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Prenestino-Labicano.
Bettoja Hotel Mediterraneo

Bettoja Hotel Mediterraneo

Via Cavour 15 Rome RM
$194 nightly
The price is $231 total per night from Dec 13 to Dec 14
$231 total
Dec 13 - Dec 14
Total with taxes and fees
8.6/10 Excellent! (995 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Prenestino-Labicano Hotel Reviews

Find out more about Prenestino-Labicano

Ready to experience the next standard in luxury? We know you're thinking about it. Add further pleasure on your next trip to Prenestino-Labicano by treating yourself to the best of the best when it comes to lodging. It's an ideal fusion. There's no reason to delay a getaway to Prenestino-Labicano any longer. You'll join the multitudes of vacationers who have made Prenestino-Labicano so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. You deserve an outstanding getaway. Our 5-star hotels in Prenestino-Labicano are the perfect places to relax in when you really need to escape.

Get a Great Deal on 5-Star Hotels in Prenestino-Labicano

You'll have a wonderful time at one of these 5-star hotels. Exceptional service, delicious meals, and attentive guest service are all waiting for you. You're sure to find exactly the accommodation you need. You can also look forward to an outstanding experience and fantastic customer care, so get ready to kick back and indulge. What kind of amenities will make your stay a wonderful one? A full-body massage to help your cares fall away? A concierge to help you plan every detail of your day? High thread-count sheets, piping hot coffees, and even space for your family pet in some cases...these hotels have it all.

You won't sleep and order room service the entire time, though. Don't worry. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Prenestino-Labicano are the perfect place to relax after a busy day. Ready to learn more? Then check out our listings and pick the perfect accommodation for your needs.

Your Getaway Starts Today

The results are in, and Prenestino-Labicano 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. It's time to indulge yourself -- Expedia can help you land a great deal on accommodation. Pick out one of Expedia's Prenestino-Labicano 5-star hotels today and dive into in total tranquility at your convenience.